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ZNF292 Gene

protein-coding   GIFtS: 51
GCID: GC06P087920

Zinc Finger Protein 292

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 2921 2     Zn-152
16 Zinc-Finger Domain Protein2     bA393I2.32
Nbla003652     Putative Protein Product Of Nbla003652
ZFP2922     KIAA05303
ZN-162     

External Ids:    HGNC: 184101   Entrez Gene: 230362   Ensembl: ENSG000001889947   UniProtKB: O602813   

Export aliases for ZNF292 gene to outside databases

Previous GC identifers: GC06P087913 GC06P087932 GC06P087857 GC06P087859 GC06P085081


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF292 Gene:
ZNF292 (zinc finger protein 292) is a protein-coding gene. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription. An important paralog of this gene is ZNF654.

UniProtKB/Swiss-Prot: ZN292_HUMAN, O60281
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF292 gene promoter:
         AML1a   Gfi-1   Evi-1   CREB   N-Myc   AREB6   deltaCREB   HFH-1   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ZNF292

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF292


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14.3   Ensembl cytogenetic band:  6q14.3   HGNC cytogenetic band: 6q15

ZNF292 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF292 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P087920:  view genomic region     (about GC identifiers)

Start:
87,862,551 bp from pter      End:
87,973,914 bp from pter
Size:
111,364 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZN292_HUMAN, O60281 (See protein sequence)
Recommended Name: Zinc finger protein 292  
Size: 2723 amino acids; 304816 Da
Sequence caution: Sequence=BAB14622.1; Type=Erroneous initiation; Sequence=BAB14654.1; Type=Erroneous initiation;
Sequence=CAD97823.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD97823.1;
Type=Frameshift; Positions=637; Sequence=CAD97823.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence.
Potential poly-A sequence;
1 PDB 3D structure from and Proteopedia for ZNF292:
1X3C (3D)    
Secondary accessions: Q5W0B2 Q7Z3L7 Q9H8G3 Q9H8J4
Alternative splicing: 2 isoforms:  O60281-1   O60281-2   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for ZNF292: NX_O60281

Explore proteomics data for ZNF292 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF292 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055836.1  
    ENSEMBL proteins: 
     ENSP00000430569   ENSP00000358590   ENSP00000428925   ENSP00000342847   ENSP00000428857  
     ENSP00000428073  

    ZNF292 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZNF292

     
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    antibodies-online peptides for ZNF292

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    antibodies-online antibodies for ZNF292 (10 products) 

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    antibodies-online kits for ZNF292 (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry O60281

    ProtoNet protein and cluster: O60281

    UniProtKB/Swiss-Prot: ZN292_HUMAN, O60281
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 15 C2H2-type zinc fingers


    Find genes that share domains with ZNF292           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN292_HUMAN, O60281
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription IEA--
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF292           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZNF292

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZNF292:
    hsa-mir-335-5p (MIRT018531), hsa-mir-21-5p (MIRT030961)

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    Selected qRT-PCR Assays for microRNAs that regulate ZNF292 (see all 88):
    hsa-miR-194* hsa-miR-323-3p hsa-miR-520e hsa-miR-300 hsa-miR-631 hsa-miR-1304 hsa-miR-3613-3p hsa-miR-200b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN292_HUMAN, O60281: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZNF292           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF292
    Interactions:

        Search GeneGlobe Interaction Network for ZNF292

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for ZNF292 (O602813 ENSP000003585904) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALBP027683, ENSP000002958974I2D: score=1 STRING: ENSP00000295897
    CDX2Q996263I2D: score=1 
    EWSR1Q018443I2D: score=1 
    GATA5Q9BWX53I2D: score=1 
    HOXA11P312703I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045944positive regulation of transcription from RNA polymerase II promoter ----

    Find genes that share ontologies with ZNF292           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF292 (ZN292)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF292 gene: 
    NM_015021.1  

    Unigene Clusters for ZNF292:

    Zinc finger protein 292
    Hs.485892  [show with all ESTs], Hs.656621  [show with all ESTs]
    Unigene Representative Sequences: NM_015021, BC040712
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392985(uc003plk.3) ENST00000369577(uc003plm.4) ENST00000369578(uc003pll.1)
    ENST00000518845 ENST00000339907 ENST00000496806 ENST00000524067 ENST00000485016
    ENST00000466062
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ZNF292 (see all 88):
    hsa-miR-194* hsa-miR-323-3p hsa-miR-520e hsa-miR-300 hsa-miR-631 hsa-miR-1304 hsa-miR-3613-3p hsa-miR-200b
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    Additional mRNA sequence: BC040712.1 

    12 DOTS entries:

    DT.99940040  DT.446298  DT.101983249  DT.97822882  DT.99942551  DT.91857141  DT.95338499  DT.121381963 
    DT.40292408  DT.91753429  DT.92006109  DT.92067573 

    Selected AceView cDNA sequences (see all 199):

    AW044400 D55742 BQ930485 AW295394 AA588646 BQ185421 AW473852 BM728355 
    AA826274 CB161174 BG573562 BF223237 BQ005431 AK127835 AW295953 BC063594 
    BM973467 AA426406 AA251587 AI474546 BM970468 BQ421523 AA808183 CB409911 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF292    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13
    SP1:                                -                             -                                       
    SP2:                                -                                                                     
    SP3:                                                                                                      
    SP4:                                -           -     -     -     -     -     -     -     -     -         
    SP5:                                -     -     -     -     -     -     -                                 


    ECgene alternative splicing isoforms for ZNF292

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF292 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTTAACCTA
    ZNF292 Expression
    About this image


    ZNF292 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             pre Conventional Dendritic Cells Peripheral Blood
     
     Eye (Sensory Organs)
             Retina
    ZNF292 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF292 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.485892 Hs.656621
        Custom PCR Arrays for ZNF292
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF292 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp2921 , 5 zinc finger protein 2921, 5 84.76(n)1
    81.87(a)1
      4 (16.86 cM)5
    300461  NM_013889.21  NP_038917.21 
     348031135 
    chicken
    (Gallus gallus)
    Aves ZNF2921 zinc finger protein 292 73.43(n)
    70.64(a)
      421828  XM_419852.4  XP_419852.3 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF2926
    zinc finger protein 292
    63(a)
    1 ↔ 1
    1(176447052-176472076)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.99132 Xenopus laevis transcribed sequence with weak similarity more 80.24(n)    48044654 
    zebrafish
    (Danio rerio)
    Actinopterygii znf292b6
    znf292a6
    zinc finger protein 292a
    32(a)
    31(a)
    1 ↔ many
    1 ↔ many
    20(217311-232690) ENSDARG00000043973
    17(49571295-49594814) ENSDARG00000016763


    ENSEMBL Gene Tree for ZNF292 (if available)
    TreeFam Gene Tree for ZNF292 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF292 gene
    ZNF6542  RLF2  ENSG000002297292  
    3 SIMAP similar genes for ZNF292 using alignment to 7 protein entries:     ZN292_HUMAN (see all proteins):
    Nbla00365    ZNF808    ZNF692

    Find genes that share paralogs with ZNF292           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF292 (see all 2411)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1428126471,2
    --87863294(+) ACCTAC/TATTAT 1 -- us2k10--------
    rs19256891,2
    C,F,A,H--87863351(+) CCCCTG/CAACCC 1 -- us2k114Minor allele frequency- C:0.46NS EA NA WA CSA 784
    rs1469986841,2
    --87863357(+) AACCCC/TCATTT 1 -- us2k10--------
    rs568477891,2
    C,F--87863387(+) TAGGTG/ATGGTG 1 -- us2k16Minor allele frequency- A:0.16WA CSA NA 246
    rs1923683561,2
    --87863533(+) TGAAAA/CCTGGT 1 -- us2k10--------
    rs1826267201,2
    --87863865(+) AGAACA/GCTTTC 1 -- us2k10--------
    rs1125959561,2
    F--87863940(+) TCCTTC/GTACTA 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1418113831,2
    --87863969(+) AGAGTA/GAATGA 1 -- us2k10--------
    rs1872559491,2
    --87864019(+) TCTGTA/GGACTA 1 -- us2k10--------
    rs792296761,2
    F--87864057(+) GTCTAA/GTGCTC 1 -- us2k11Minor allele frequency- G:0.01WA 118

    HapMap Linkage Disequilibrium report for ZNF292 (87862551 - 87973914 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZNF292:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv268184CNV Insertion20981092
    dgv1991e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): ZNF292
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF292
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF292

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZNF292           About GenesLikeMe

    Genetic Association Database (GAD): ZNF292
    Human Genome Epidemiology (HuGE) Navigator: ZNF292 (1 document)

    Export disorders for ZNF292 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF292 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with ZNF292)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)1, 2, 3 Nagase T....Ohara O. (DNA Res. 1998)
    2. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. (PubMed id 21116278)1, 4 Furney S.J.... . (Mol. Psychiatry 2011)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A catalogue of putative HIV-1 protease host cell substrates. (PubMed id 22944692)1 Impens F....Gevaert K. (Biol. Chem. 2012)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    7. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)
    8. Growth hormone transcription factor ZN-16 genomic coding regions are composed of a single exon and are evolutionarily conserved in mammals. (PubMed id 16303260)1 Flynn M.P. and Hurley D.L. (Gene 2006)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    10. Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. (PubMed id 16112646)1 Guinn B.-A.... Mufti G.J. (Biochem. Biophys. Res. Commun. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23036 HGNC: 18410 AceView: ZNF292 Ensembl:ENSG00000188994 euGenes: HUgn23036
    ECgene: ZNF292 H-InvDB: ZNF292

    (According to HUGE)
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    HUGE: KIAA0530

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZNF292 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF292 gene:
    Search GeneIP for patents involving ZNF292

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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