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Aliases for ZNF292 Gene

Aliases for ZNF292 Gene

  • Zinc Finger Protein 292 2 3 5
  • Putative Protein Product Of Nbla00365 3
  • 16 Zinc-Finger Domain Protein 3
  • Nbla00365 3
  • BA393I2.3 3
  • KIAA0530 4
  • ZFP292 3
  • ZN-16 3
  • Zn-15 3

External Ids for ZNF292 Gene

Previous GeneCards Identifiers for ZNF292 Gene

  • GC06P087913
  • GC06P087932
  • GC06P087857
  • GC06P087859
  • GC06P087920
  • GC06P085081

Summaries for ZNF292 Gene

GeneCards Summary for ZNF292 Gene

ZNF292 (Zinc Finger Protein 292) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. An important paralog of this gene is RLF.

UniProtKB/Swiss-Prot for ZNF292 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF292 Gene

Genomics for ZNF292 Gene

Regulatory Elements for ZNF292 Gene

Enhancers for ZNF292 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF292 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF292 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF292 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF292 Gene

Chromosome:
6
Start:
87,152,833 bp from pter
End:
87,264,196 bp from pter
Size:
111,364 bases
Orientation:
Plus strand

Genomic View for ZNF292 Gene

Genes around ZNF292 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF292 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF292 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF292 Gene

Proteins for ZNF292 Gene

  • Protein details for ZNF292 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O60281-ZN292_HUMAN
    Recommended name:
    Zinc finger protein 292
    Protein Accession:
    O60281
    Secondary Accessions:
    • Q5W0B2
    • Q7Z3L7
    • Q9H8G3
    • Q9H8J4

    Protein attributes for ZNF292 Gene

    Size:
    2723 amino acids
    Molecular mass:
    304816 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14622.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB14654.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD97823.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD97823.1; Type=Frameshift; Positions=637; Evidence={ECO:0000305}; Sequence=CAD97823.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZNF292 Gene

    Alternative splice isoforms for ZNF292 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF292 Gene

Proteomics data for ZNF292 Gene at MOPED

Post-translational modifications for ZNF292 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF292 Gene

No data available for DME Specific Peptides for ZNF292 Gene

Domains & Families for ZNF292 Gene

Gene Families for ZNF292 Gene

Protein Domains for ZNF292 Gene

Suggested Antigen Peptide Sequences for ZNF292 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O60281

UniProtKB/Swiss-Prot:

ZN292_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF292: view

Function for ZNF292 Gene

Molecular function for ZNF292 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF292 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with ZNF292: view

Phenotypes for ZNF292 Gene

genes like me logo Genes that share phenotypes with ZNF292: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF292 Gene

Localization for ZNF292 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF292 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF292 Gene COMPARTMENTS Subcellular localization image for ZNF292 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF292 Gene

Pathways & Interactions for ZNF292 Gene

SuperPathways for ZNF292 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF292 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF292 Gene

Drugs & Compounds for ZNF292 Gene

No Compound Related Data Available

Transcripts for ZNF292 Gene

Unigene Clusters for ZNF292 Gene

Zinc finger protein 292:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF292 Gene

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13
SP1: - -
SP2: -
SP3:
SP4: - - - - - - - - - -
SP5: - - - - - - -

Relevant External Links for ZNF292 Gene

GeneLoc Exon Structure for
ZNF292
ECgene alternative splicing isoforms for
ZNF292

Expression for ZNF292 Gene

mRNA expression in normal human tissues for ZNF292 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF292 Gene

This gene is overexpressed in Retina (46.3), Liver, secretome (11.7), and Platelet (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF292 Gene



SOURCE GeneReport for Unigene cluster for ZNF292 Gene Hs.485892

genes like me logo Genes that share expression patterns with ZNF292: view

Protein tissue co-expression partners for ZNF292 Gene

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF292 Gene

Orthologs for ZNF292 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF292 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF292 35
  • 91.05 (n)
  • 91.42 (a)
ZNF292 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF292 35
  • 93.42 (n)
  • 93.57 (a)
ZNF292 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp292 35
  • 84.76 (n)
  • 81.87 (a)
Zfp292 16
Zfp292 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF292 35
  • 99.56 (n)
  • 99.63 (a)
ZNF292 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp292 35
  • 85.23 (n)
  • 82.52 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF292 36
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF292 36
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF292 35
  • 73.43 (n)
  • 70.64 (a)
ZNF292 36
  • 69 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF292 36
  • 63 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.7312 35
znf292 35
  • 59.47 (n)
  • 52.37 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.9913 35
zebrafish
(Danio rerio)
Actinopterygii znf292a 36
  • 31 (a)
OneToMany
znf292b 36
  • 32 (a)
OneToMany
Species with no ortholog for ZNF292:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF292 Gene

ENSEMBL:
Gene Tree for ZNF292 (if available)
TreeFam:
Gene Tree for ZNF292 (if available)

Paralogs for ZNF292 Gene

Paralogs for ZNF292 Gene

(3) SIMAP similar genes for ZNF292 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF292: view

Variants for ZNF292 Gene

Sequence variations from dbSNP and Humsavar for ZNF292 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs9362415 - 87,258,847(+) CTTCA(A/G)TAAAT reference, missense
rs6910541 - 87,259,762(+) AACTT(A/G)TAGAA reference, missense
rs1058665 -- 87,262,829(+) AAACT(G/T)TATAA utr-variant-3-prime
rs1065846 -- 87,184,866(-) ggata(C/T)gagaa intron-variant
rs1080522 -- 87,194,855(-) ACCAT(C/G)TGTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF292 Gene

Variant ID Type Subtype PubMed ID
dgv1991e1 CNV Complex 17122850
esv268184 CNV Insertion 20981092

Variation tolerance for ZNF292 Gene

Residual Variation Intolerance Score: 8.25% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.17; 69.61% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF292 Gene

Human Gene Mutation Database (HGMD)
ZNF292

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF292 Gene

Disorders for ZNF292 Gene

Relevant External Links for ZNF292

Genetic Association Database (GAD)
ZNF292
Human Genome Epidemiology (HuGE) Navigator
ZNF292
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF292

No disorders were found for ZNF292 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF292 Gene

Publications for ZNF292 Gene

  1. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PMID: 9628581) Nagase T. … Ohara O. (DNA Res. 1998) 2 3 4 67
  2. Transposon mutagenesis identifies genes and evolutionary forces driving gastrointestinal tract tumor progression. (PMID: 25559195) Takeda H. … Jenkins N.A. (Nat. Genet. 2015) 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. A catalogue of putative HIV-1 protease host cell substrates. (PMID: 22944692) Impens F. … Gevaert K. (Biol. Chem. 2012) 3

Products for ZNF292 Gene

Sources for ZNF292 Gene

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