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Aliases for ZNF287 Gene

Aliases for ZNF287 Gene

  • Zinc Finger Protein 287 2 3
  • Zinc Finger Protein With KRAB And SCAN Domains 13 3 4
  • ZKSCAN13 3 4
  • ZSCAN45 3

External Ids for ZNF287 Gene

Previous GeneCards Identifiers for ZNF287 Gene

  • GC17M016816
  • GC17M017565
  • GC17M016397
  • GC17M016655
  • GC17M016395
  • GC17M016320
  • GC17M016453

Summaries for ZNF287 Gene

Entrez Gene Summary for ZNF287 Gene

  • This gene encodes a member of the krueppel family of zinc finger proteins, suggesting a role as a transcription factor. Its specific function has not been determined. This gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF287 Gene

ZNF287 (Zinc Finger Protein 287) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF529.

UniProtKB/Swiss-Prot for ZNF287 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF287 Gene

Genomics for ZNF287 Gene

Regulatory Elements for ZNF287 Gene

Genomic Location for ZNF287 Gene

Start:
16,550,312 bp from pter
End:
16,569,206 bp from pter
Size:
18,895 bases
Orientation:
Minus strand

Genomic View for ZNF287 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF287 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF287 Gene

Proteins for ZNF287 Gene

  • Protein details for ZNF287 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HBT7-ZN287_HUMAN
    Recommended name:
    Zinc finger protein 287
    Protein Accession:
    Q9HBT7
    Secondary Accessions:
    • Q6IAG1

    Protein attributes for ZNF287 Gene

    Size:
    754 amino acids
    Molecular mass:
    87565 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF287 Gene

Proteomics data for ZNF287 Gene at MOPED

Post-translational modifications for ZNF287 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF287 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF287 Gene

Domains for ZNF287 Gene

Gene Families for ZNF287 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF287 Gene

Graphical View of Domain Structure for InterPro Entry

Q9HBT7

UniProtKB/Swiss-Prot:

ZN287_HUMAN :
  • Q9HBT7
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF287: view

Function for ZNF287 Gene

Molecular function for ZNF287 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF287 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF287: view

Phenotypes for ZNF287 Gene

GenomeRNAi human phenotypes for ZNF287:
genes like me logo Genes that share phenotypes with ZNF287: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF287 Gene

Localization for ZNF287 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF287 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF287 Gene COMPARTMENTS Subcellular localization image for ZNF287 gene
Compartment Confidence
nucleus 4
cytosol 2
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ZNF287 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF287: view

Pathways for ZNF287 Gene

SuperPathways for ZNF287 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF287: view

Pathways by source for ZNF287 Gene

2 Reactome pathways for ZNF287 Gene

Interacting Proteins for ZNF287 Gene

Gene Ontology (GO) - Biological Process for ZNF287 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter --
GO:0006366 transcription from RNA polymerase II promoter --
GO:0014003 oligodendrocyte development --
genes like me logo Genes that share ontologies with ZNF287: view

Transcripts for ZNF287 Gene

Unigene Clusters for ZNF287 Gene

Zinc finger protein 287:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF287

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF287

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF287 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8
SP1: - - -
SP2: - -
SP3: - -
SP4: - -
SP5: - - - - -
SP6: -

Relevant External Links for ZNF287 Gene

GeneLoc Exon Structure for
ZNF287
ECgene alternative splicing isoforms for
ZNF287

Expression for ZNF287 Gene

mRNA expression in normal human tissues for ZNF287 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF287 Gene Hs.99724

genes like me logo Genes that share expressions with ZNF287: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF287 Gene

Orthologs for ZNF287 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF287 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF287 35
  • 99.74 (n)
  • 99.74 (a)
ZNF287 36
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF135 36
  • 43 (a)
OneToOne
ZNF287 35
  • 85.34 (n)
  • 87.81 (a)
dog
(Canis familiaris)
Mammalia ZNF287 35
  • 91.75 (n)
  • 90.92 (a)
ZNF287 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp287 35
  • 83.27 (n)
  • 84.06 (a)
Zfp287 16
Zfp287 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 45 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
-- 36
  • 41 (a)
OneToMany
-- 36
  • 41 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
-- 36
  • 41 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
-- 36
  • 41 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp287 35
  • 85.97 (n)
  • 86.81 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG2120 37
  • 36 (a)
CG8301 37
  • 32 (a)
CG10543 37
  • 30 (a)
CG6654 37
  • 40 (a)
worm
(Caenorhabditis elegans)
Secernentea Y55F3AM.14 37
  • 36 (a)
Species with no ortholog for ZNF287:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZNF287 Gene

ENSEMBL:
Gene Tree for ZNF287 (if available)
TreeFam:
Gene Tree for ZNF287 (if available)

Paralogs for ZNF287 Gene

Selected SIMAP similar genes for ZNF287 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF287: view

Variants for ZNF287 Gene

Sequence variations from dbSNP and Humsavar for ZNF287 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs546844 -- 16,569,963(-) attgt(C/T)cttca upstream-variant-2KB
rs553665 -- 16,550,437(-) TTTTA(A/G)TGGAG utr-variant-3-prime
rs2970068 -- 16,554,506(+) CTTCT(C/G)TAGAT intron-variant
rs6502511 -- 16,561,253(+) aggtt(G/T)cagtg intron-variant
rs6502512 -- 16,570,293(+) aatta(A/T)aacat upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF287 Gene

Variant ID Type Subtype PubMed ID
esv2715702 CNV Deletion 23290073

Relevant External Links for ZNF287 Gene

HapMap Linkage Disequilibrium report
ZNF287

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF287 Gene

Disorders for ZNF287 Gene

No disorders were found for ZNF287 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF287 Gene

Publications for ZNF287 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for ZNF287 Gene

Sources for ZNF287 Gene

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