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Aliases for ZNF287 Gene

Aliases for ZNF287 Gene

  • Zinc Finger Protein 287 2 3 5
  • Zinc Finger Protein With KRAB And SCAN Domains 13 3 4
  • ZKSCAN13 3 4
  • ZSCAN45 3

External Ids for ZNF287 Gene

Previous GeneCards Identifiers for ZNF287 Gene

  • GC17M016816
  • GC17M017565
  • GC17M016397
  • GC17M016655
  • GC17M016395
  • GC17M016320
  • GC17M016453

Summaries for ZNF287 Gene

Entrez Gene Summary for ZNF287 Gene

  • This gene encodes a member of the krueppel family of zinc finger proteins, suggesting a role as a transcription factor. Its specific function has not been determined. This gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF287 Gene

ZNF287 (Zinc Finger Protein 287) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA polymerase II transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF274.

UniProtKB/Swiss-Prot for ZNF287 Gene

  • May be involved in transcriptional regulation.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF287 Gene

Genomics for ZNF287 Gene

Regulatory Elements for ZNF287 Gene

Enhancers for ZNF287 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF287 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF287 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF287 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF287 Gene

16,549,913 bp from pter
16,569,206 bp from pter
19,294 bases
Minus strand

Genomic View for ZNF287 Gene

Genes around ZNF287 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF287 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF287 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF287 Gene

Proteins for ZNF287 Gene

  • Protein details for ZNF287 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 287
    Protein Accession:
    Secondary Accessions:
    • Q6IAG1

    Protein attributes for ZNF287 Gene

    754 amino acids
    Molecular mass:
    87565 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF287 Gene

Proteomics data for ZNF287 Gene at MOPED

Post-translational modifications for ZNF287 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF287 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF287 Gene

Domains & Families for ZNF287 Gene

Gene Families for ZNF287 Gene

Suggested Antigen Peptide Sequences for ZNF287 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF287: view

Function for ZNF287 Gene

Molecular function for ZNF287 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF287: view

Animal Models for ZNF287 Gene

MGI Knock Outs for ZNF287:

Animal Model Products

CRISPR Products

miRNA for ZNF287 Gene

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ZNF287 Gene

Localization for ZNF287 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF287 Gene

Subcellular locations from

Jensen Localization Image for ZNF287 Gene COMPARTMENTS Subcellular localization image for ZNF287 gene
Compartment Confidence
nucleus 5
golgi apparatus 3
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF287 Gene

Pathways & Interactions for ZNF287 Gene

SuperPathways for ZNF287 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF287: view

Pathways by source for ZNF287 Gene

2 Reactome pathways for ZNF287 Gene

Interacting Proteins for ZNF287 Gene

Gene Ontology (GO) - Biological Process for ZNF287 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042035 regulation of cytokine biosynthetic process IEA --
GO:0045893 positive regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF287: view

No data available for SIGNOR curated interactions for ZNF287 Gene

Drugs & Compounds for ZNF287 Gene

No Compound Related Data Available

Transcripts for ZNF287 Gene

Unigene Clusters for ZNF287 Gene

Zinc finger protein 287:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF287 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8
SP1: - - -
SP2: - -
SP3: - -
SP4: - -
SP5: - - - - -
SP6: -

Relevant External Links for ZNF287 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF287 Gene

mRNA expression in normal human tissues for ZNF287 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF287 Gene Hs.99724

genes like me logo Genes that share expression patterns with ZNF287: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF287 Gene

Orthologs for ZNF287 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF287 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF287 35
  • 85.34 (n)
  • 87.81 (a)
ZNF135 36
  • 43 (a)
(Canis familiaris)
Mammalia ZNF287 35
  • 91.75 (n)
  • 90.92 (a)
ZNF287 36
  • 88 (a)
(Mus musculus)
Mammalia Zfp287 35
  • 83.27 (n)
  • 84.06 (a)
Zfp287 16
Zfp287 36
  • 80 (a)
(Pan troglodytes)
Mammalia ZNF287 35
  • 99.74 (n)
  • 99.74 (a)
ZNF287 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Zfp287 35
  • 85.97 (n)
  • 86.81 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 45 (a)
-- 36
  • 45 (a)
-- 36
  • 43 (a)
-- 36
  • 39 (a)
-- 36
  • 39 (a)
-- 36
  • 41 (a)
-- 36
  • 41 (a)
-- 36
  • 49 (a)
-- 36
  • 46 (a)
-- 36
  • 50 (a)
-- 36
  • 42 (a)
-- 36
  • 41 (a)
-- 36
  • 42 (a)
-- 36
  • 41 (a)
-- 36
  • 48 (a)
-- 36
  • 39 (a)
-- 36
  • 45 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10543 37
  • 30 (a)
CG2120 37
  • 36 (a)
CG6654 37
  • 40 (a)
CG8301 37
  • 32 (a)
(Caenorhabditis elegans)
Secernentea Y55F3AM.14 37
  • 36 (a)
Species with no ortholog for ZNF287:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZNF287 Gene

Gene Tree for ZNF287 (if available)
Gene Tree for ZNF287 (if available)

Paralogs for ZNF287 Gene

Paralogs for ZNF287 Gene

(426) SIMAP similar genes for ZNF287 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF287: view

Variants for ZNF287 Gene

Sequence variations from dbSNP and Humsavar for ZNF287 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs7224723 - 16,553,300(+) CACCT(G/T)TTCCT reference, missense
rs546844 -- 16,569,963(-) attgt(C/T)cttca upstream-variant-2KB
rs553665 -- 16,550,437(-) TTTTA(A/G)TGGAG utr-variant-3-prime
rs2970068 -- 16,554,506(+) CTTCT(C/G)TAGAT intron-variant
rs6502511 -- 16,561,253(+) aggtt(G/T)cagtg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF287 Gene

Variant ID Type Subtype PubMed ID
esv2715702 CNV Deletion 23290073

Variation tolerance for ZNF287 Gene

Residual Variation Intolerance Score: 14.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.46; 43.24% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF287 Gene

Disorders for ZNF287 Gene

Relevant External Links for ZNF287

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF287 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF287 Gene

Publications for ZNF287 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Zinc fingers: DNA binding and protein-protein interactions. (PMID: 11021307) Leon O. … Roth M. (Biol. Res. 2000) 3
  5. The biology of the mammalian KrA1ppel-like family of transcription factors. (PMID: 11137451) Dang D.T. … Yang V.W. (Int. J. Biochem. Cell Biol. 2000) 3

Products for ZNF287 Gene

Sources for ZNF287 Gene