ZNF286B Gene
protein-coding GIFtS: 31
GCID: GC17M018561
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zinc finger protein 286B(Previous names: zinc finger protein 286-like, zinc finger 286C pseudogene...)
(Previous symbols: ZNF286L, ZNF286C)
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Aliases
for ZNF286B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 286B1 2 | | Zinc Finger 286C Pseudogene1 2 | | ZNF286C1 2 3 | | Zinc Finger Protein 286-Like1 | | ZNF286L1 2 3 | | Putative Zinc Finger Protein 286B2 | | ZNF5901 2 | | Zinc Finger Protein 5902 |
Export aliases for ZNF286B gene to outside databasesPrevious GC identifers: GC17U900825 GC17M018511 |
Summaries
for ZNF286B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: Z286B_HUMAN, P0CG31Function: May be involved in transcriptional regulation (By similarity)
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Genomic Views
for ZNF286B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF286B gene promoter:
Spz1 Olf-1 Evi-1 MEF-2A POU2F1 POU2F1a SEF-1 (1) STAT3 aMEF-2 MRF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF286B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF286B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.2ZNF286B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M018561: view genomic region
(about GC identifiers)
Start:
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18,561,742 bp from pter |
End:
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18,585,575 bp from pter |
Size:
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23,834 bases |
Orientation:
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minus strand |
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Proteins
for ZNF286B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: Z286B_HUMAN, P0CG31 (See
protein sequence)Recommended Name: Putative zinc finger protein 286B Size: 522 amino acids; 59572 Da
Subcellular location: Nucleus (Probable)
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for ZNF286B: NX_P0CG31
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0CG31
ZNF286B Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001138517.1
ENSEMBL proteins: ENSP00000460210 ENSP00000462368 ENSP00000463300 ENSP00000460736 ENSP00000461413
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF286B for ontologies About GeneDecksing
ZNF286B Antibody Products:
Assay Products for ZNF286B: |
Protein
Domains /
Families
for ZNF286B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF286B for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P0CG31ProtoNet protein and cluster: P0CG31 UniProtKB/Swiss-Prot: Z286B_HUMAN, P0CG31Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 10 C2H2-type zinc fingers |
Function
for ZNF286B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: Z286B_HUMAN, P0CG31Function: May be involved in transcriptional regulation (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF286B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF286B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF286B |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF286B for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF286B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF286B
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF286B for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF286B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF286B
Search CenterWatch for drugs/clinical trials and news about ZNF286B / Z286B
|
Transcripts
for ZNF286B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF286B gene: NM_001145045.1 Unigene Cluster for ZNF286B: Zinc finger protein 286B Hs.534279 [show with all ESTs]Unigene Representative Sequence: NM_0011450457 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000285274 ENST00000580145 ENST00000583002 ENST00000443457 ENST00000442380
ENST00000454745 ENST00000545289(uc010vyd.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF286B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF286B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF286B (NM_001145045) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF286B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF286B |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF286B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF286B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF286B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF286B |
7 DOTS entries: DT.121012357 DT.92017894 DT.97835074 DT.95325248 DT.120974353 DT.120922656 DT.75137230
GeneLoc Exon Structure
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Expression
for ZNF286B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF286B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for ZNF286B
SOURCE GeneReport for Unigene cluster: Hs.534279
SABiosciences Custom PCR Arrays for ZNF286B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF286B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF286B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF286B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF286B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF286B |
Orthologs
for ZNF286B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF286B (if available)
TreeFam Gene Tree for ZNF286B (if available) |
Paralogs
for ZNF286B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF286B gene
- ZNF7132 ZFP69B2 ZNF286A2 ZFP692 ZNF792 ZNF3912 ZNF5142
18/505 SIMAP similar genes for ZNF286B using alignment to 5 protein entries: Z286B_HUMAN (see all proteins)
(see all similar genes):ZNF286A ZNF78L1 ZNF818P kr-znf3 ZNF22 ZNF808
ZFP41 ZNF24 ZFS-4 ZNF211 ZNF56 ZNF883
ZSCAN22 DKFZp686M04222 HZF30 HZF36 ZNF662 ZNF787
ZNF286B for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF286B
PGOHUM00000241229
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Genomic Variants
for ZNF286B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF286B (18561742 - 18585575 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ZNF286B
3 CNVs: 4993 30808 88369 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ZNF286B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF286B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF286B gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF286B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)1, 2 Zody M.C.... Nusbaum C. (2006)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF286B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ZNF286B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing ZNF286B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF286B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF286B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZNF286B gene:
Search GeneIP for patents involving ZNF286B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF286B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
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 | | | ZNF286B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF286B |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF286B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF286B |
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