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Aliases for ZNF286B Gene

Aliases for ZNF286B Gene

  • Zinc Finger Protein 286B 2 3 5
  • Zinc Finger 286C Pseudogene 2 3
  • Zinc Finger Protein 590 2 3
  • ZNF286C 3 4
  • ZNF286L 3 4
  • Zinc Finger Protein 286-Like 2
  • ZNF590 3

External Ids for ZNF286B Gene

Previous HGNC Symbols for ZNF286B Gene

  • ZNF286L
  • ZNF286C

Previous GeneCards Identifiers for ZNF286B Gene

  • GC17U900825
  • GC17M018511
  • GC17M018561

Summaries for ZNF286B Gene

GeneCards Summary for ZNF286B Gene

ZNF286B (Zinc Finger Protein 286B) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF501.

UniProtKB/Swiss-Prot for ZNF286B Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF286B Gene

Genomics for ZNF286B Gene

Regulatory Elements for ZNF286B Gene

Promoters for ZNF286B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF286B on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF286B Gene

Chromosome:
17
Start:
18,658,429 bp from pter
End:
18,682,262 bp from pter
Size:
23,834 bases
Orientation:
Minus strand

Genomic View for ZNF286B Gene

Genes around ZNF286B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF286B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF286B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF286B Gene

Proteins for ZNF286B Gene

  • Protein details for ZNF286B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG31-Z286B_HUMAN
    Recommended name:
    Putative zinc finger protein 286B
    Protein Accession:
    P0CG31

    Protein attributes for ZNF286B Gene

    Size:
    522 amino acids
    Molecular mass:
    59572 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF286B Gene

Proteomics data for ZNF286B Gene at MOPED

Post-translational modifications for ZNF286B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF286B Gene

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for ZNF286B

No data available for DME Specific Peptides for ZNF286B Gene

Domains & Families for ZNF286B Gene

Gene Families for ZNF286B Gene

Protein Domains for ZNF286B Gene

Suggested Antigen Peptide Sequences for ZNF286B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CG31

UniProtKB/Swiss-Prot:

Z286B_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF286B: view

Function for ZNF286B Gene

Molecular function for ZNF286B Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF286B Gene

GenomeRNAi human phenotypes for ZNF286B:
genes like me logo Genes that share phenotypes with ZNF286B: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF286B Gene

Localization for ZNF286B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF286B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF286B Gene COMPARTMENTS Subcellular localization image for ZNF286B gene
Compartment Confidence
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF286B Gene

Pathways & Interactions for ZNF286B Gene

SuperPathways for ZNF286B Gene

No Data Available

Interacting Proteins for ZNF286B Gene

Gene Ontology (GO) - Biological Process for ZNF286B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF286B Gene

Drugs & Compounds for ZNF286B Gene

No Compound Related Data Available

Transcripts for ZNF286B Gene

mRNA/cDNA for ZNF286B Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF286B Gene

Zinc finger protein 286B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF286B Gene

No ASD Table

Relevant External Links for ZNF286B Gene

GeneLoc Exon Structure for
ZNF286B
ECgene alternative splicing isoforms for
ZNF286B

Expression for ZNF286B Gene

mRNA expression in normal human tissues for ZNF286B Gene

mRNA differential expression in normal tissues according to GTEx for ZNF286B Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x4.1).

SOURCE GeneReport for Unigene cluster for ZNF286B Gene Hs.534279

genes like me logo Genes that share expression patterns with ZNF286B: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF286B Gene

Orthologs for ZNF286B Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF286B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF286A 36
  • 86 (a)
OneToMany
cow
(Bos Taurus)
Mammalia ZNF286A 36
  • 77 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 79 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp286 36
  • 72 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 59 (a)
OneToMany
Species with no ortholog for ZNF286B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF286B Gene

ENSEMBL:
Gene Tree for ZNF286B (if available)
TreeFam:
Gene Tree for ZNF286B (if available)

Paralogs for ZNF286B Gene

Paralogs for ZNF286B Gene

(513) SIMAP similar genes for ZNF286B Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF286B Gene

genes like me logo Genes that share paralogs with ZNF286B: view

Variants for ZNF286B Gene

Sequence variations from dbSNP and Humsavar for ZNF286B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1058987 -- 18,677,892(-) ATTTA(A/G)AAAAA intron-variant
rs2055333 -- 18,657,947(+) cagcc(A/G)tgcat downstream-variant-500B
rs2240600 -- 18,682,382(+) TGAGG(C/T)TGGGA upstream-variant-2KB
rs2601941 -- 18,682,761(-) AACTC(A/G)TTTTA upstream-variant-2KB
rs2601945 -- 18,680,429(-) TGTGG(C/T)ACATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF286B Gene

Variant ID Type Subtype PubMed ID
nsv827913 CNV Gain 20364138
nsv9504 CNV Gain+Loss 18304495
nsv907782 CNV Gain 21882294
nsv499818 OTHER Inversion 21111241
nsv833389 CNV Gain 17160897
nsv523721 CNV Gain 19592680

Variation tolerance for ZNF286B Gene

Residual Variation Intolerance Score: 92.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 17.28; 98.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF286B Gene

HapMap Linkage Disequilibrium report
ZNF286B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF286B Gene

Disorders for ZNF286B Gene

Relevant External Links for ZNF286B

Genetic Association Database (GAD)
ZNF286B
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF286B

No disorders were found for ZNF286B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF286B Gene

Publications for ZNF286B Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF286B Gene

Sources for ZNF286B Gene

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