ZNF285 Gene
protein-coding GIFtS: 43
GCID: GC19M044886
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zinc finger protein 285(Previous name: zinc finger protein 285A )
(Previous symbol: ZNF285A)
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Aliases
for ZNF285 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 2851 2 | | Zinc Finger Protein 285A1 2 3 | | ZNF285A1 2 3 |
Export aliases for ZNF285 gene to outside databasesPrevious GC identifers: GC00U990660 GC19U900206 GC19M049578 GC19M041321 |
Summaries
for ZNF285 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN285_HUMAN, Q96NJ3Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF285 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF285
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF285
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF285 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.32ZNF285 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M044886: view genomic region
(about GC identifiers)
Start:
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44,886,459 bp from pter |
End:
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44,905,777 bp from pter |
Size:
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19,319 bases |
Orientation:
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minus strand |
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Proteins
for ZNF285 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN285_HUMAN, Q96NJ3 (See
protein sequence)Recommended Name: Zinc finger protein 285 Size: 590 amino acids; 68261 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q17RJ3 Q6B0A8 Q6ISR5Alternative splicing: 2 isoforms: Q96NJ3-1 Q96NJ3-2 Explore the universe of human proteins at neXtProt for ZNF285: NX_Q96NJ3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96NJ3
ZNF285 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689567.3
ENSEMBL proteins: ENSP00000333595 ENSP00000439431 ENSP00000464788 ENSP00000468399 ENSP00000467795 Reactome Protein details: Q96NJ3
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF285 for ontologies About GeneDecksing
ZNF285 Antibody Products:
Assay Products for ZNF285: |
Protein
Domains /
Families
for ZNF285 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF285 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96NJ3ProtoNet protein and cluster: Q96NJ3 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN285_HUMAN, Q96NJ3Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 11 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF285 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN285_HUMAN, Q96NJ3Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF285
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF285 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF285 (NM_152354) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF285 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF285 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF285 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF285 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF285 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF285
ZNF285 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF285
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF285 for ontologies About GeneDecksing
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Drugs & Compounds
for ZNF285 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF285
Search CenterWatch for drugs/clinical trials and news about ZNF285 / ZN285
|
Transcripts
for ZNF285 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF285 gene: NM_152354.3 Unigene Cluster for ZNF285: Zinc finger protein 285 Hs.709428 [show with all ESTs]Unigene Representative Sequence: AL8334476 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000330997(uc010xxa.2 uc002ozd.4) ENST00000544719 ENST00000591679
ENST00000585868 ENST00000589738 ENST00000589885
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF285
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF285 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF285 (NM_152354) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF285 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF285 |
Additional cDNA sequence: AK055309.1 AL833447.1 AY166790.1 BC069384.1 BC074824.2 BC074875.2 BC117300.1 BC117302.1 BC143984.1 3 DOTS entries: DT.400938 DT.121459491 DT.121459486 24/25 AceView cDNA sequences (see all 25): NM_152354 BX282010 AA716578 AW513227 BF343511 AI208630 AW183184 BX643240 BM987858 BC069384 BC074824 AY166790 AI208631 AK055309 BM681972 BQ215606 BC074875 BM729030 AL833447 AA813778 BX488656 BF352512 AI369486 AW812382
GeneLoc Exon Structure
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Expression
for ZNF285 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF285 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAAAATTCA
About this image
See ZNF285 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF285
SOURCE GeneReport for Unigene cluster: Hs.709428
SABiosciences Custom PCR Arrays for ZNF285
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF285
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF285 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF285 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF285 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF285 |
Orthologs
for ZNF285 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF285 (if available)
TreeFam Gene Tree for ZNF285 (if available) |
Paralogs
for ZNF285 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF285 gene
- ZNF2292 ZNF2232 ZNF2302 ENSG000000623702 ZNF1552 ZNF6642 ZNF2272 ZNF2392
- ZNF2342 ZNF2242 ZNF2252 ZNF2262 ZNF2142 ZNF2222 ZNF2842 ENSG000002671732
- ZNF452 ZNF2352 ZNF2212 ENSG000002670222 ZNF2332
18/510 SIMAP similar genes for ZNF285 using alignment to 5 protein entries: ZN285_HUMAN (see all proteins)
(see all similar genes):ZNF285A ZNF806 ZFS-4 ZNF224 ZNF56 MGC12518
ZNF846 ZNF789 ZNF226 ZSCAN16 ZNF559 ZNF230
DKFZp686M04222 ZNF ZNF235 ZNF589 ZNF433 ZNF234
ZNF285 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF285 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF285 (44886459 - 44905777 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF285: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF285 |
|
Disorders
/ Diseases
for ZNF285 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF285 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF285 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF285) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PubMed id 12743021)1 Shannon M.... Stubbs L. (2003)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF285 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing ZNF285 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF285 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF285 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF285 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZNF285 gene:
Search GeneIP for patents involving ZNF285
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF285 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF285 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF285 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF285 | | | OriGene Protein Over-expression Lysate for ZNF285 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF285 | | OriGene 3'-UTR Clone for ZNF285 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF285 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF285 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF285 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF285 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF285 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF285 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF285 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF285 |
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| | | | Search Tocris compounds for ZNF285 |
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 | | | ZNF285 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF285 |
|  |  |  | | | | ThermoFisher Antibodies for ZNF285 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF285 |
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