Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF284 Gene

Aliases for ZNF284 Gene

  • Zinc Finger Protein 284 2 3
  • ZNF284L 3 4

External Ids for ZNF284 Gene

Previous GeneCards Identifiers for ZNF284 Gene

  • GC00U990661
  • GC19P049252
  • GC19P049268
  • GC19U900427
  • GC19P044578
  • GC19P041008
  • GC19P044580

Summaries for ZNF284 Gene

GeneCards Summary for ZNF284 Gene

ZNF284 (Zinc Finger Protein 284) is a Protein Coding gene. An important paralog of this gene is ZNF155.

UniProtKB/Swiss-Prot for ZNF284 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF284 Gene

Genomics for ZNF284 Gene

Regulatory Elements for ZNF284 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF284 Gene

Start:
44,072,144 bp from pter
End:
44,089,613 bp from pter
Size:
17,470 bases
Orientation:
Plus strand

Genomic View for ZNF284 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF284 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF284 Gene

Proteins for ZNF284 Gene

  • Protein details for ZNF284 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2VY69-ZN284_HUMAN
    Recommended name:
    Zinc finger protein 284
    Protein Accession:
    Q2VY69
    Secondary Accessions:
    • Q86WM1

    Protein attributes for ZNF284 Gene

    Size:
    593 amino acids
    Molecular mass:
    69019 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF284 Gene

Proteomics data for ZNF284 Gene at MOPED

Post-translational modifications for ZNF284 Gene

  • Ubiquitination at Lys509 and Lys512
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF284 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF284 Gene

Domains for ZNF284 Gene

Gene Families for ZNF284 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF284 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q2VY69

UniProtKB/Swiss-Prot:

ZN284_HUMAN :
  • Q2VY69
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF284: view

Function for ZNF284 Gene

Molecular function for ZNF284 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF284 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF284: view

Animal Model Products

CRISPR Products

miRNA for ZNF284 Gene

miRTarBase miRNAs that target ZNF284

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF284

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF284 Gene

Localization for ZNF284 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF284 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF284 Gene COMPARTMENTS Subcellular localization image for ZNF284 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF284 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF284: view

Pathways for ZNF284 Gene

SuperPathways for ZNF284 Gene

No Data Available

Interacting Proteins for ZNF284 Gene

Gene Ontology (GO) - Biological Process for ZNF284 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF284: view

No data available for Pathways by source for ZNF284 Gene

Transcripts for ZNF284 Gene

mRNA/cDNA for ZNF284 Gene

(11) Selected AceView cDNA sequences:
(5) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF284 Gene

Zinc finger protein 284:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF284

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF284
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF284 Gene

No ASD Table

Relevant External Links for ZNF284 Gene

GeneLoc Exon Structure for
ZNF284
ECgene alternative splicing isoforms for
ZNF284

Expression for ZNF284 Gene

mRNA expression in normal human tissues for ZNF284 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF284 Gene

SOURCE GeneReport for Unigene cluster for ZNF284 Gene Hs.445395

mRNA Expression by UniProt/SwissProt for ZNF284 Gene

Q2VY69-ZN284_HUMAN
Tissue specificity: Expressed in lung, liver, pancreas and thymus. Lower expression in heart, placenta, spleen, prostate, ovary, small intestine and colon. No expression seen in brain, skeletal muscle, kidney, testis and peripheral blood leukocyte.
genes like me logo Genes that share expressions with ZNF284: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF284 Gene

Orthologs for ZNF284 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF284 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF284 35
  • 99.46 (n)
  • 99.28 (a)
ZNF284 36
  • 99 (a)
OneToOne
Species with no ortholog for ZNF284:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF284 Gene

ENSEMBL:
Gene Tree for ZNF284 (if available)
TreeFam:
Gene Tree for ZNF284 (if available)

Paralogs for ZNF284 Gene

Selected SIMAP similar genes for ZNF284 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF284: view

Variants for ZNF284 Gene

Sequence variations from dbSNP and Humsavar for ZNF284 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs4410194 -- 44,072,927(+) TTGGC(C/T)ACTGA intron-variant, upstream-variant-2KB
rs4550576 -- 44,074,294(+) gttgc(A/G)gtgag intron-variant, upstream-variant-2KB
rs4553729 -- 44,081,923(+) atcaG(C/T)GTTCA intron-variant
rs4803673 -- 44,080,403(+) ACCAG(C/T)CTGGC intron-variant
rs4803674 -- 44,081,006(+) GTTTG(A/T)TGTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF284 Gene

Variant ID Type Subtype PubMed ID
nsv833840 CNV Gain 17160897

Relevant External Links for ZNF284 Gene

HapMap Linkage Disequilibrium report
ZNF284

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF284 Gene

Disorders for ZNF284 Gene

No disorders were found for ZNF284 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF284 Gene

Publications for ZNF284 Gene

  1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 2 3 4
  2. Cloning and characterization of a novel KRAB-domain-containing zinc finger gene (ZNF284L). (PMID: 16817023) Yin G. … Mao Y. (Mol. Biol. Rep. 2006) 3 4
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF284 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF284
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF284
    • Block miRNA regulation of ZNF284 using miScript Target Protectors

    Sources for ZNF284 Gene

    Back to Top

    Content