ZNF283 Gene
protein-coding GIFtS: 39
GCID: GC19P044272
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|
zinc finger protein 283
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Aliases
for ZNF283 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 2831 2 | | Zinc Finger Protein HZF192 3 | | HZF192 | | HZF412 | | Zinc Finger Protein 412 |
Export aliases for ZNF283 gene to outside databasesPrevious GC identifers: GC00U990662 GC19P049007 GC19P049023 GC19P049016 |
Summaries
for ZNF283 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN283_HUMAN, Q8N7M2Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF283 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF283 gene promoter:
POU2F1 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF283
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF283 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.31 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.31ZNF283 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P044272: view genomic region
(about GC identifiers)
Start:
|
44,331,444 bp from pter |
End:
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44,353,307 bp from pter |
Size:
|
21,864 bases |
Orientation:
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plus strand |
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Proteins
for ZNF283 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN283_HUMAN, Q8N7M2 (See
protein sequence)Recommended Name: Zinc finger protein 283 Size: 679 amino acids; 77942 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAC05251.1; Type=Miscellaneous discrepancy; Note=Compared to the genome, the sequence lacks6 bp for unexplained reasons;
Secondary accessions: B4DGZ5 B7WP04 Q6RFR9 Q86WM6Explore the universe of human proteins at neXtProt for ZNF283: NX_Q8N7M2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N7M2
ZNF283 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_862828.1
ENSEMBL proteins: ENSP00000327314 ENSP00000468708 ENSP00000465054 ENSP00000468508 ENSP00000465942 ENSP00000467328 ENSP00000312519
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF283 for ontologies About GeneDecksing
ZNF283 Antibody Products:
Assay Products for ZNF283: |
Protein
Domains /
Families
for ZNF283 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF283 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N7M2ProtoNet protein and cluster: Q8N7M2 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN283_HUMAN, Q8N7M2Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 15 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF283 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN283_HUMAN, Q8N7M2Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF283
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF283
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ZNF283 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF283 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF283 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF283 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF283 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF283
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF283 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF283 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF283
Search CenterWatch for drugs/clinical trials and news about ZNF283 / ZN283
|
Transcripts
for ZNF283 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF283 gene: NM_181845.1 Unigene Cluster for ZNF283: Zinc finger protein 283 Hs.652513 [show with all ESTs]Unigene Representative Sequence: AK2948529 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000324461(uc002oxr.4 uc002oxp.4) ENST00000591203 ENST00000588797
ENST00000586976 ENST00000590950 ENST00000593268 ENST00000588967 ENST00000593164
ENST00000310738
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF283
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF283
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF283 (NM_181845) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF283 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF283 |
Additional cDNA sequence: AK098175.1 AK294852.1 AY166784.1 AY500359.1 AY500364.1 BC045755.2 5 DOTS entries: DT.100689708 DT.92416361 DT.438972 DT.91926158 DT.121499332 24/27 AceView cDNA sequences (see all 27): AY166784 AA351493 BU101805 BF840630 BE261849 AY500364 BX473427 AI753038 N57666 BC045755 AA351492 BP872606 AY500359 AK098175 BG715255 AV752188 BV208044 BV208043 AA081943 BM688312 AA082636 AW080602 BG980994 BF959034
GeneLoc Exon Structure
|
Expression
for ZNF283 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF283 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAGAACTCA
About this image
Genevestigator expression for ZNF283
SOURCE GeneReport for Unigene cluster: Hs.652513
UniProtKB/Swiss-Prot: ZN283_HUMAN, Q8N7M2Tissue specificity: Detected in prostate, testis, and pancreas
SABiosciences Custom PCR Arrays for ZNF283
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF283
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF283 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF283 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF283 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF283 |
Orthologs
for ZNF283 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF283 (if available)
TreeFam Gene Tree for ZNF283 (if available) |
Paralogs
for ZNF283 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF283 gene
- ZNF4202 ZNF5292 ZFP302 ZNF1402 ZNF780A2 ZNF3832 ZNF7902 ZNF5822
- ZFP822 ZNF302 ZNF5732 ZNF5402 ZNF5712 ZNF3312 ZFP142 ZNF4612
- ZNF4042 ZNF8292 ZNF6072 ZNF5652 ZNF5662 ENSG000002675522
18/597 SIMAP similar genes for ZNF283 using alignment to 7 protein entries: ZN283_HUMAN (see all proteins)
(see all similar genes):HZF41 APOPT1 NRAMP1 ZNF78L1 ZNF721 ZNF571
ZFP90 ZNF707 ZNF519 ZNF850 ZNF140 AVGR4
AVGR5 ZNF818P ZNF595 ZNF331 ZNF793 ZNF527
ZNF283 for paralogs About GeneDecksing
5/12 Pseudogenes.org Pseudogenes for ZNF283 (see all 12)
PGOHUM00000258671 PGOHUM00000259211 PGOHUM00000259326 PGOHUM00000259327 PGOHUM00000259404
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Genomic Variants
for ZNF283 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF283 (44331444 - 44353307 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF283: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF283 |
|
Disorders
/ Diseases
for ZNF283 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF283 for disorders About GeneDecksing
1  disease for ZNF283: About MalaCardsprostatitis
Export disorders for ZNF283 gene to outside databases
|
Publications
for ZNF283 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF283 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF283) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PubMed id 12743021)1, 2, 3 Shannon M.... Stubbs L. (2003)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PubMed id 7865130)1, 2 Abrink M.... Hellman L. (1995)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF283 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF283 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF283 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF283 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF283 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF283 gene:
Search GeneIP for patents involving ZNF283
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF283 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF283 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF283 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF283 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF283 | | OriGene 3'-UTR Clone for ZNF283 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF283 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF283 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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 | | | ZNF283 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF283 |
|  |  |  | | | | ThermoFisher Antibodies for ZNF283 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF283 |
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