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Aliases for ZNF283 Gene

Aliases for ZNF283 Gene

  • Zinc Finger Protein 283 2 3
  • Zinc Finger Protein HZF19 3 4
  • Zinc Finger Protein 41 3
  • HZF19 3
  • HZF41 3

External Ids for ZNF283 Gene

Summaries for ZNF283 Gene

GeneCards Summary for ZNF283 Gene

ZNF283 (Zinc Finger Protein 283) is a Protein Coding gene. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF283 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF283 Gene

Genomics for ZNF283 Gene

Genomic Location for ZNF283 Gene

Start:
43,827,292 bp from pter
End:
43,852,017 bp from pter
Size:
24,726 bases
Orientation:
Plus strand

Genomic View for ZNF283 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF283 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF283 Gene

Regulatory Elements for ZNF283 Gene

Transcription factor binding sites by QIAGEN in the ZNF283 gene promoter:

Proteins for ZNF283 Gene

  • Protein details for ZNF283 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7M2-ZN283_HUMAN
    Recommended name:
    Zinc finger protein 283
    Protein Accession:
    Q8N7M2
    Secondary Accessions:
    • B4DGZ5
    • B7WP04
    • Q6RFR9
    • Q86WM6

    Protein attributes for ZNF283 Gene

    Size:
    679 amino acids
    Molecular mass:
    77942 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05251.1; Type=Miscellaneous discrepancy; Note=Compared to the genome, the sequence lacks 6 bp for unexplained reasons.; Evidence={ECO:0000305};

neXtProt entry for ZNF283 Gene

Proteomics data for ZNF283 Gene at MOPED

Post-translational modifications for ZNF283 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF283 Gene

Domains for ZNF283 Gene

Gene Families for ZNF283 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN283_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q8N7M2
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8N7M2
Similarity:
  • Contains 15 C2H2-type zinc fingers.:
    • Q8N7M2
genes like me logo Genes that share domains with ZNF283: view

Function for ZNF283 Gene

Molecular function for ZNF283 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF283 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF283: view

miRNA for ZNF283 Gene

miRTarBase miRNAs that target ZNF283

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF283 Gene

Localization for ZNF283 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF283 Gene

Gene Ontology (GO) - Cellular Components for ZNF283 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF283: view

Pathways for ZNF283 Gene

SuperPathways for ZNF283 Gene

No Data Available

Interacting Proteins for ZNF283 Gene

Gene Ontology (GO) - Biological Process for ZNF283 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF283: view

No data available for Pathways by source for ZNF283 Gene

Transcripts for ZNF283 Gene

Unigene Clusters for ZNF283 Gene

Zinc finger protein 283:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF283 Gene

No ASD Table

Relevant External Links for ZNF283 Gene

GeneLoc Exon Structure for
ZNF283
ECgene alternative splicing isoforms for
ZNF283

Expression for ZNF283 Gene

mRNA expression in normal human tissues for ZNF283 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF283 Gene

SOURCE GeneReport for Unigene cluster for ZNF283 Gene Hs.652513

mRNA Expression by UniProt/SwissProt for ZNF283 Gene

Q8N7M2-ZN283_HUMAN
Tissue specificity: Detected in prostate, testis, and pancreas.
genes like me logo Genes that share expressions with ZNF283: view

Orthologs for ZNF283 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF283 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF283 36
  • 96.76 (n)
  • 94.26 (a)
ZNF283 37
  • 83 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF283 36
  • 90.06 (n)
  • 86.66 (a)
ZNF283 37
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF283 36
  • 86.11 (n)
  • 81.96 (a)
ZNF283 37
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 46 (a)
OneToMany
Species with no ortholog for ZNF283:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF283 Gene

ENSEMBL:
Gene Tree for ZNF283 (if available)
TreeFam:
Gene Tree for ZNF283 (if available)

Paralogs for ZNF283 Gene

Selected SIMAP similar genes for ZNF283 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF283: view

Variants for ZNF283 Gene

Sequence variations from dbSNP and Humsavar for ZNF283 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs173238 -- 43,840,320(+) GCAGT(C/T)ATCTG intron-variant
rs189445 -- 43,827,558(+) GGGGG(C/T)GCTGG intron-variant
rs349029 -- 43,828,364(+) TTCCT(A/T)GGCCT intron-variant
rs349030 -- 43,827,658(+) CAGAC(A/G)GCGTG intron-variant
rs349035 -- 43,839,530(+) tttct(C/G)tactt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF283 Gene

Variant ID Type Subtype PubMed ID
nsv458710 CNV Loss 19166990
nsv524460 CNV Loss 19592680

Relevant External Links for ZNF283 Gene

HapMap Linkage Disequilibrium report
ZNF283

Disorders for ZNF283 Gene

No disorders were found for ZNF283 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF283 Gene

Publications for ZNF283 Gene

  1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PMID: 7865130) Abrink M. … Hellman L. (DNA Cell Biol. 1995) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PMID: 23535729) Michailidou K. … Easton D.F. (Nat. Genet. 2013) 3

Products for ZNF283 Gene

Sources for ZNF283 Gene

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