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Aliases for ZNF280C Gene

Aliases for ZNF280C Gene

  • Zinc Finger Protein 280C 2 3
  • Suppressor Of Hairy Wing Homolog 3 3 4
  • Zinc Finger Protein 633 3 4
  • ZNF633 3 4
  • SUHW3 3 4
  • Suppressor Of Hairy Wing Homolog 3 (Drosophila) 2

External Ids for ZNF280C Gene

Previous HGNC Symbols for ZNF280C Gene

  • SUHW3

Previous GeneCards Identifiers for ZNF280C Gene

  • GC0XM129166
  • GC0XM129336
  • GC0XM118731

Summaries for ZNF280C Gene

Entrez Gene Summary for ZNF280C Gene

  • This gene encodes a member of the zinc finger domain-containing protein family. This family member contains multiple Cys2-His2(C2H2)-type zinc finger domains, the most common type of zinc finger domain that self-folds to form a beta-beta-alpha structure that binds a zinc ion. [provided by RefSeq, Aug 2011]

GeneCards Summary for ZNF280C Gene

ZNF280C (Zinc Finger Protein 280C) is a Protein Coding gene. An important paralog of this gene is POGZ.

UniProtKB/Swiss-Prot for ZNF280C Gene

  • May function as a transcription factor

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF280C Gene

Genomics for ZNF280C Gene

Regulatory Elements for ZNF280C Gene

Genomic Location for ZNF280C Gene

Start:
130,202,699 bp from pter
End:
130,268,948 bp from pter
Size:
66,250 bases
Orientation:
Minus strand

Genomic View for ZNF280C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF280C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF280C Gene

Proteins for ZNF280C Gene

  • Protein details for ZNF280C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8ND82-Z280C_HUMAN
    Recommended name:
    Zinc finger protein 280C
    Protein Accession:
    Q8ND82
    Secondary Accessions:
    • A8K2V8
    • Q9NXR3

    Protein attributes for ZNF280C Gene

    Size:
    737 amino acids
    Molecular mass:
    83096 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA90947.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};

neXtProt entry for ZNF280C Gene

Proteomics data for ZNF280C Gene at MOPED

Post-translational modifications for ZNF280C Gene

  • Ubiquitination at Lys689
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF280C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF280C Gene

Domains for ZNF280C Gene

Protein Domains for ZNF280C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF280C Gene

Graphical View of Domain Structure for InterPro Entry

Q8ND82

UniProtKB/Swiss-Prot:

Z280C_HUMAN :
  • Q8ND82
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF280C: view

No data available for Gene Families for ZNF280C Gene

Function for ZNF280C Gene

Molecular function for ZNF280C Gene

UniProtKB/Swiss-Prot Function: May function as a transcription factor

Gene Ontology (GO) - Molecular Function for ZNF280C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF280C: view

Animal Model Products

CRISPR Products

miRNA for ZNF280C Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF280C

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF280C Gene

Localization for ZNF280C Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF280C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF280C Gene COMPARTMENTS Subcellular localization image for ZNF280C gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF280C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF280C: view

Pathways for ZNF280C Gene

SuperPathways for ZNF280C Gene

No Data Available

Interacting Proteins for ZNF280C Gene

Gene Ontology (GO) - Biological Process for ZNF280C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF280C: view

No data available for Pathways by source for ZNF280C Gene

Transcripts for ZNF280C Gene

mRNA/cDNA for ZNF280C Gene

Unigene Clusters for ZNF280C Gene

Zinc finger protein 280C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF280C

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF280C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF280C Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
SP1:
SP2: -

Relevant External Links for ZNF280C Gene

GeneLoc Exon Structure for
ZNF280C
ECgene alternative splicing isoforms for
ZNF280C

Expression for ZNF280C Gene

mRNA expression in normal human tissues for ZNF280C Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF280C Gene

SOURCE GeneReport for Unigene cluster for ZNF280C Gene Hs.308418

genes like me logo Genes that share expressions with ZNF280C: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF280C Gene

Orthologs for ZNF280C Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF280C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF280C 35
  • 98.58 (n)
  • 96.81 (a)
cow
(Bos Taurus)
Mammalia ZNF280C 35
  • 78.6 (n)
  • 66.72 (a)
ZNF280C 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF280C 35
  • 85.77 (n)
  • 77.82 (a)
ZNF280C 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp280c 35
  • 78.29 (n)
  • 68.47 (a)
Zfp280c 36
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 49 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 61 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp280c 35
  • 77.78 (n)
  • 68.21 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 43 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 36 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii znf280d 36
  • 35 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta row 36
  • 12 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F37D6.2 36
  • 18 (a)
OneToMany
Species with no ortholog for ZNF280C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF280C Gene

ENSEMBL:
Gene Tree for ZNF280C (if available)
TreeFam:
Gene Tree for ZNF280C (if available)

Paralogs for ZNF280C Gene

Paralogs for ZNF280C Gene

Selected SIMAP similar genes for ZNF280C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF280C: view

Variants for ZNF280C Gene

Sequence variations from dbSNP and Humsavar for ZNF280C Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs172332 -- 130,211,146(+) GAAAA(C/T)ATCCT intron-variant
rs182331 -- 130,251,408(-) atttt(C/T)tgcat intron-variant
rs209207 -- 130,263,991(+) ctgca(C/T)tccag intron-variant
rs209208 -- 130,264,530(+) GATTC(C/T)CTGGG intron-variant
rs209209 -- 130,264,553(+) TATAC(A/G)TAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF280C Gene

Variant ID Type Subtype PubMed ID
nsv528290 CNV Gain 19592680

Relevant External Links for ZNF280C Gene

HapMap Linkage Disequilibrium report
ZNF280C
Locus Specific Mutation Databases (LSDB)
ZNF280C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF280C Gene

Disorders for ZNF280C Gene

No disorders were found for ZNF280C Gene.

No data available for UniProtKB/Swiss-Prot for ZNF280C Gene

Publications for ZNF280C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF280C Gene

Sources for ZNF280C Gene

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