Aliases for ZNF280B Gene
External Ids for ZNF280B Gene
Previous HGNC Symbols for ZNF280B Gene
Previous GeneCards Identifiers for ZNF280B Gene
The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]
GeneCards Summary for ZNF280B Gene
ZNF280B (Zinc Finger Protein 280B) is a Protein Coding gene. An important paralog of this gene is POGZ.
UniProtKB/Swiss-Prot for ZNF280B Gene
May function as a transcription factor.