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Aliases for ZNF280A Gene

Aliases for ZNF280A Gene

  • Zinc Finger Protein 280A 2 3
  • Suppressor Of Hairy Wing Homolog 1 3 4
  • Zinc Finger Protein 280 2 3
  • Zinc Finger Protein 636 3 4
  • 3OY11.1 3 4
  • ZNF280 3 4
  • ZNF636 3 4
  • SUHW1 3 4
  • Suppressor Of Hairy Wing Homolog 1 (Drosophila) 2

External Ids for ZNF280A Gene

Previous HGNC Symbols for ZNF280A Gene

  • ZNF280
  • SUHW1

Previous GeneCards Identifiers for ZNF280A Gene

  • GC22M021198
  • GC22M022868
  • GC22M005826

Summaries for ZNF280A Gene

Entrez Gene Summary for ZNF280A Gene

  • This gene encodes a zinc finger protein. The encoded protein contains 4 C2H2-type zinc fingers, which are commonly found in transcription factors. A variety of functions may be performed by this type of zinc finger protein, including the binding of DNA or RNA. [provided by RefSeq, Apr 2014]

GeneCards Summary for ZNF280A Gene

ZNF280A (Zinc Finger Protein 280A) is a Protein Coding gene. An important paralog of this gene is POGZ.

UniProtKB/Swiss-Prot for ZNF280A Gene

  • May function as a transcription factor

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF280A Gene

Genomics for ZNF280A Gene

Regulatory Elements for ZNF280A Gene

Genomic Location for ZNF280A Gene

Start:
22,513,736 bp from pter
End:
22,520,270 bp from pter
Size:
6,535 bases
Orientation:
Minus strand

Genomic View for ZNF280A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF280A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF280A Gene

Proteins for ZNF280A Gene

  • Protein details for ZNF280A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P59817-Z280A_HUMAN
    Recommended name:
    Zinc finger protein 280A
    Protein Accession:
    P59817
    Secondary Accessions:

    Protein attributes for ZNF280A Gene

    Size:
    542 amino acids
    Molecular mass:
    60816 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF280A Gene

Proteomics data for ZNF280A Gene at MOPED

Post-translational modifications for ZNF280A Gene

No Post-translational modifications

Other Protein References for ZNF280A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF280A Gene

Domains for ZNF280A Gene

Protein Domains for ZNF280A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ZNF280A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P59817

UniProtKB/Swiss-Prot:

Z280A_HUMAN :
  • P59817
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF280A: view

No data available for Gene Families for ZNF280A Gene

Function for ZNF280A Gene

Molecular function for ZNF280A Gene

UniProtKB/Swiss-Prot Function: May function as a transcription factor

Gene Ontology (GO) - Molecular Function for ZNF280A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF280A: view

Phenotypes for ZNF280A Gene

genes like me logo Genes that share phenotypes with ZNF280A: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF280A Gene

Localization for ZNF280A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF280A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF280A Gene COMPARTMENTS Subcellular localization image for ZNF280A gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF280A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF280A: view

Pathways for ZNF280A Gene

SuperPathways for ZNF280A Gene

No Data Available

Interacting Proteins for ZNF280A Gene

Gene Ontology (GO) - Biological Process for ZNF280A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF280A: view

No data available for Pathways by source for ZNF280A Gene

Transcripts for ZNF280A Gene

mRNA/cDNA for ZNF280A Gene

(8) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF280A Gene

Zinc finger protein 280A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF280A Gene

No ASD Table

Relevant External Links for ZNF280A Gene

GeneLoc Exon Structure for
ZNF280A
ECgene alternative splicing isoforms for
ZNF280A

Expression for ZNF280A Gene

mRNA expression in normal human tissues for ZNF280A Gene

mRNA differential expression in normal tissues according to GTEx for ZNF280A Gene

This gene is overexpressed in Adrenal Gland (34.3) and Testis (5.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF280A Gene

SOURCE GeneReport for Unigene cluster for ZNF280A Gene Hs.178665

genes like me logo Genes that share expressions with ZNF280A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF280A Gene

Orthologs for ZNF280A Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF280A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF280A 35
  • 98.83 (n)
  • 97.41 (a)
ZNF280A 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF280A 35
  • 73.77 (n)
  • 58.49 (a)
ZNF280A 36
  • 57 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF280A 35
  • 74.71 (n)
  • 60.24 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 30 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 40 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 36
  • 25 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 22 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii znf280d 36
  • 22 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta row 36
  • 9 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F37D6.2 36
  • 16 (a)
OneToMany
Species with no ortholog for ZNF280A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF280A Gene

ENSEMBL:
Gene Tree for ZNF280A (if available)
TreeFam:
Gene Tree for ZNF280A (if available)

Paralogs for ZNF280A Gene

Paralogs for ZNF280A Gene

Selected SIMAP similar genes for ZNF280A Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF280A Gene

genes like me logo Genes that share paralogs with ZNF280A: view

Variants for ZNF280A Gene

Sequence variations from dbSNP and Humsavar for ZNF280A Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs361535 -- 22,521,898(+) TGGCT(C/T)GAGCC upstream-variant-2KB
rs361554 -- 22,519,390(+) atcgc(A/G)ccgtg intron-variant
rs361555 -- 22,518,563(+) tgggc(A/G)gatca intron-variant
rs361558 -- 22,513,887(+) ACTGT(A/G)AAAAA utr-variant-3-prime
rs361561 -- 22,518,680(+) ctact(A/C)gggag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF280A Gene

Variant ID Type Subtype PubMed ID
nsv7350 OTHER Inversion 18451855
nsv526328 CNV Gain 19592680
nsv459421 CNV Gain 19166990
nsv817937 CNV Loss 17921354
dgv548n27 CNV Loss 19166990
esv2422480 CNV Deletion 17116639
nsv828977 CNV Loss 20364138
nsv828979 CNV Gain+Loss 20364138
dgv731n67 CNV Loss 20364138
dgv550n27 CNV Loss 19166990
dgv38n64 CNV Loss 17921354
dgv551n27 CNV Loss 19166990
nsv438338 CNV Loss 16468122
nsv834149 CNV Loss 17160897
esv1007524 CNV Gain 20482838
nsv469735 CNV Loss 16826518
dgv39n64 CNV Loss 17921354
dgv23n14 CNV Loss 18776910
dgv555n27 CNV Loss 19166990
dgv556n27 CNV Loss 19166990
dgv557n27 CNV Loss 19166990
dgv558n27 CNV Loss 19166990
nsv819428 CNV Gain 19587683
nsv514963 CNV Complex 21397061
nsv834150 CNV Loss 17160897
nsv459539 CNV Loss 19166990
nsv821694 CNV Loss 15273396
nsv817957 CNV Gain 17921354
nsv915211 CNV Loss 21882294
nsv915212 CNV Gain 21882294
nsv508727 CNV Insertion 20534489
nsv511072 CNV Complex 20534489
nsv459548 CNV Loss 19166990
esv33016 CNV Gain 17666407
dgv4898n71 CNV Loss 21882294
nsv194 CNV Insertion 15895083
nsv3571 CNV Insertion 18451855
dgv560n27 CNV Loss 19166990
nsv433336 CNV Loss 18776910
dgv4899n71 CNV Loss 21882294

Relevant External Links for ZNF280A Gene

HapMap Linkage Disequilibrium report
ZNF280A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF280A Gene

Disorders for ZNF280A Gene

No disorders were found for ZNF280A Gene.

No data available for UniProtKB/Swiss-Prot for ZNF280A Gene

Publications for ZNF280A Gene

  1. One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PMID: 9074928) Kawasaki K. … Shimizu N. (Genome Res. 1997) 2 3 4
  2. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF280A Gene

Sources for ZNF280A Gene

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