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Aliases for ZNF276 Gene

Aliases for ZNF276 Gene

  • Zinc Finger Protein 276 2 3 5
  • Zinc Finger Protein 477 3 4
  • Centromere Protein Z 2 3
  • Zfp-276 3 4
  • ZFP276 3 4
  • ZNF477 3 4
  • Zinc Finger Protein 276 Homolog (Mouse) 2
  • Zinc Finger Protein 276 Homolog 3
  • Zinc Finger, AD-Type 3
  • Zinc Finger 2
  • AD-Type 2
  • CENP-Z 3
  • CENPZ 3
  • ZADT 3

External Ids for ZNF276 Gene

Previous HGNC Symbols for ZNF276 Gene

  • ZFP276

Previous GeneCards Identifiers for ZNF276 Gene

  • GC16P088315
  • GC16P089788
  • GC16P075482

Summaries for ZNF276 Gene

GeneCards Summary for ZNF276 Gene

ZNF276 (Zinc Finger Protein 276) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZFP91.

UniProtKB/Swiss-Prot for ZNF276 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF276 Gene

Genomics for ZNF276 Gene

Regulatory Elements for ZNF276 Gene

Enhancers for ZNF276 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF276 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF276 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF276 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF276 Gene

89,720,195 bp from pter
89,740,925 bp from pter
20,731 bases
Plus strand

Genomic View for ZNF276 Gene

Genes around ZNF276 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF276 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF276 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF276 Gene

Proteins for ZNF276 Gene

  • Protein details for ZNF276 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 276
    Protein Accession:
    Secondary Accessions:
    • Q0VGA1
    • Q2TBE8
    • Q3B7H7

    Protein attributes for ZNF276 Gene

    614 amino acids
    Molecular mass:
    67219 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH32781.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAI10349.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF276 Gene


neXtProt entry for ZNF276 Gene

Proteomics data for ZNF276 Gene at MOPED

Post-translational modifications for ZNF276 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF276 Gene

No data available for DME Specific Peptides for ZNF276 Gene

Domains & Families for ZNF276 Gene

Gene Families for ZNF276 Gene

Suggested Antigen Peptide Sequences for ZNF276 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 ZAD (zinc-finger associated) domain.
  • Contains 5 C2H2-type zinc fingers.
  • Contains 1 ZAD (zinc-finger associated) domain.
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF276: view

Function for ZNF276 Gene

Molecular function for ZNF276 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF276 Gene

GenomeRNAi human phenotypes for ZNF276:
genes like me logo Genes that share phenotypes with ZNF276: view

Animal Model Products

CRISPR Products

miRNA for ZNF276 Gene

miRTarBase miRNAs that target ZNF276

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF276 Gene

Localization for ZNF276 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF276 Gene

Subcellular locations from

Jensen Localization Image for ZNF276 Gene COMPARTMENTS Subcellular localization image for ZNF276 gene
Compartment Confidence
nucleus 5
cytosol 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF276 Gene

Pathways & Interactions for ZNF276 Gene

SuperPathways for ZNF276 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF276 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF276 Gene

Drugs & Compounds for ZNF276 Gene

No Compound Related Data Available

Transcripts for ZNF276 Gene

Unigene Clusters for ZNF276 Gene

Zinc finger protein 276:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF276 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16
SP1: -
SP2: - - - -
SP3: - -
SP4: -
SP6: - -
SP8: -

Relevant External Links for ZNF276 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF276 Gene

mRNA expression in normal human tissues for ZNF276 Gene

Protein differential expression in normal tissues from HIPED for ZNF276 Gene

This gene is overexpressed in Colon muscle (22.5), Peripheral blood mononuclear cells (16.0), Pancreatic juice (10.6), and Bone (10.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF276 Gene

SOURCE GeneReport for Unigene cluster for ZNF276 Gene Hs.290154

genes like me logo Genes that share expression patterns with ZNF276: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF276 Gene

Orthologs for ZNF276 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF276 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF276 35
  • 82.61 (n)
  • 79.77 (a)
ZNF276 36
  • 81 (a)
(Canis familiaris)
Mammalia ZNF276 35
  • 85.66 (n)
  • 85.38 (a)
ZNF276 36
  • 84 (a)
(Mus musculus)
Mammalia Zfp276 35
  • 81.75 (n)
  • 80.88 (a)
Zfp276 16
Zfp276 36
  • 80 (a)
(Pan troglodytes)
Mammalia ZNF276 35
  • 99.46 (n)
  • 99.51 (a)
ZNF276 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Zfp276 35
  • 82.56 (n)
  • 82.34 (a)
(Monodelphis domestica)
Mammalia ZNF276 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF276 36
  • 73 (a)
(Gallus gallus)
Aves ZNF276 35
  • 70.15 (n)
  • 67.5 (a)
ZNF276 36
  • 64 (a)
(Anolis carolinensis)
Reptilia ZNF276 36
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia znf276 35
  • 59.65 (n)
  • 58.25 (a)
(Danio rerio)
Actinopterygii Dr.19956 35
im:7141269 36
  • 19 (a)
zgc:171673 36
  • 19 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 15 (a)
Species with no ortholog for ZNF276:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF276 Gene

Gene Tree for ZNF276 (if available)
Gene Tree for ZNF276 (if available)

Paralogs for ZNF276 Gene

Paralogs for ZNF276 Gene

genes like me logo Genes that share paralogs with ZNF276: view

Variants for ZNF276 Gene

Sequence variations from dbSNP and Humsavar for ZNF276 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
VAR_019125 -
VAR_019126 -
rs6500437 - 89,723,490(+) GGCCA(C/T)GGGAC nc-transcript-variant, reference, synonymous-codon, missense
rs17719249 - 89,727,323(+) ATGAT(C/T)GGGTA nc-transcript-variant, reference, synonymous-codon, missense
rs4293383 -- 89,732,259(+) ccaga(C/G)ttttg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF276 Gene

Variant ID Type Subtype PubMed ID
nsv428331 CNV Gain+Loss 18775914
dgv3008n71 CNV Loss 21882294
dgv3009n71 CNV Loss 21882294
nsv509639 CNV Insertion 20534489
nsv907420 CNV Loss 21882294
nsv457623 CNV Gain 19166990
nsv907424 CNV Loss 21882294
nsv907425 CNV Loss 21882294
nsv833330 CNV Loss 17160897
dgv3012n71 CNV Loss 21882294
nsv516241 CNV Loss 19592680
nsv907429 CNV Loss 21882294
nsv1931 CNV Insertion 18451855
esv1995159 CNV Deletion 18987734
esv1401930 CNV Insertion 17803354
nsv833331 CNV Gain+Loss 17160897
esv2715199 CNV Deletion 23290073
esv25585 CNV Loss 19812545
dgv424e201 CNV Deletion 23290073
dgv517e199 CNV Deletion 23128226
esv2672413 CNV Deletion 23128226
nsv907430 CNV Gain 21882294
nsv457624 CNV Loss 19166990

Variation tolerance for ZNF276 Gene

Residual Variation Intolerance Score: 68.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.20; 52.12% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF276 Gene

Disorders for ZNF276 Gene

Relevant External Links for ZNF276

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF276 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF276 Gene

Publications for ZNF276 Gene

  1. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. (PMID: 20813266) Ohta S. … Rappsilber J. (Cell 2010) 2 3 67
  2. Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA. (PMID: 10936049) Wong J.C. … Buchwald M. (Genomics 2000) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF276 Gene

Sources for ZNF276 Gene