ZNF275 Gene
protein-coding GIFtS: 40
GCID: GC0XP152599
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|
zinc finger protein 275
| |
Aliases
for ZNF275 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 2751 2 |
Export aliases for ZNF275 gene to outside databasesPrevious GC identifers: GC0XP146763 GC0XP149081 GC0XP150161 GC0XP151040 GC0XP151031 GC0XP152093 GC0XP152252 GC0XP141258 |
Summaries
for ZNF275 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZNF275:
This gene encodes a zinc finger protein that appears to be conserved in eutheria. Its function has not yet beenestablished. (provided by RefSeq, Jul 2010)
UniProtKB/Swiss-Prot: ZN275_HUMAN, Q9NSD4Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF275 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167198.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF275 gene promoter:
LHX3b/Lhx3b STAT1 STAT1beta HSF1 (long) FOXD1 E4BP4 STAT1alpha E47 c-Ets-1 HSF1short
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF275
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF275 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28ZNF275 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP152599: view genomic region
(about GC identifiers)
Start:
|
152,599,613 bp from pter |
End:
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152,618,384 bp from pter |
Size:
|
18,772 bases |
Orientation:
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plus strand |
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Proteins
for ZNF275 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN275_HUMAN, Q9NSD4 (See
protein sequence)Recommended Name: Zinc finger protein 275 Size: 429 amino acids; 48443 Da
Subcellular location: Nucleus (Probable)Explore the universe of human proteins at neXtProt for ZNF275: NX_Q9NSD4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NSD4
ZNF275 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001073954.3
ENSEMBL proteins: ENSP00000359271 ENSP00000359269 ENSP00000398977 ENSP00000411097
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF275 for ontologies About GeneDecksing
ZNF275 Antibody Products:
Assay Products for ZNF275: |
Protein
Domains /
Families
for ZNF275 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF275 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NSD4ProtoNet protein and cluster: Q9NSD4 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN275_HUMAN, Q9NSD4Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 11 C2H2-type zinc fingers |
Function
for ZNF275 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN275_HUMAN, Q9NSD4Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF275 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF275
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ZNF275 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF275 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF275 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF275 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF275 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF275
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF275 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF275 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF275
Search CenterWatch for drugs/clinical trials and news about ZNF275 / ZN275
|
Transcripts
for ZNF275 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF275 gene (2 alternative transcripts): NM_020636.2 NM_001080485.3 Unigene Cluster for ZNF275: Zinc finger protein 275 Hs.348963 [show with all ESTs]Unigene Representative Sequence: NM_0010804854 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000370251 ENST00000370249(uc011myn.2) ENST00000421401(uc004fhg.2)
ENST00000440091(uc022cht.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF275 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF275
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF275 (NM_001080485) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF275 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF275 |
Additional cDNA sequence: AK122976.1 AK127133.1 AK172795.1 AL833683.1 BC001545.1 BC018767.1 BC041602.1 BC136634.1 5 DOTS entries: DT.447402 DT.100745697 DT.86855250 DT.40208354 DT.95341403 24/148 AceView cDNA sequences (see all 148): AW513558 T54762 BM453266 AI081787 BP431994 AA287968 BC018767 AI127094 AA074589 BF970444 AI435588 AK122976 BF513252 BF793625 BU845685 BU727493 H82982 AI084640 AA625845 AL833683 F11046 BM543848 BV177478 BM998290
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF275 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b |
|---|
|
| SP1: | | | | | | | | | |
| SP2: | | | | | | | | |
ECgene alternative splicing isoforms for ZNF275
|
Expression
for ZNF275 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF275 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTGATCCCC
About this image
See ZNF275 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF275
SOURCE GeneReport for Unigene cluster: Hs.348963
SABiosciences Custom PCR Arrays for ZNF275
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF275
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF275 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF275 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF275 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF275 |
Orthologs
for ZNF275 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF275 gene from 2/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Zfp2751 , 5 |
zinc finger protein 2751, 5 |
85.7(n)1
88.01(a)1 |
|
X (37.29 cM)5
270811 NM_031494.21 NP_113682.21
733426215 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG109593 |
-- |
37(a) |
|
7D16 -- |
ENSEMBL Gene Tree for ZNF275 (if available)
TreeFam Gene Tree for ZNF275 (if available) |
Paralogs
for ZNF275 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZNF275 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF275 (152599613 - 152618384 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF275: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF275 |
|
Disorders
/ Diseases
for ZNF275 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF275 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF275 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF275) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Comparative genome sequence analysis of the Bpa/Str region in mouse and man. (PubMed id 10854409)1, 2 Mallon A.-M....Brown S.D.M. (2000)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF275 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF275 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF275 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF275 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF275 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF275 gene:
Search GeneIP for patents involving ZNF275
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF275 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF275 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF275 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF275 | | | OriGene Protein Over-expression Lysate for ZNF275 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF275 | | OriGene 3'-UTR Clone for ZNF275 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF275 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF275 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | ZNF275 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF275 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF275 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF275 |
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