Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF275 Gene

Aliases for ZNF275 Gene

  • Zinc Finger Protein 275 2 3 5

External Ids for ZNF275 Gene

Previous GeneCards Identifiers for ZNF275 Gene

  • GC0XP146763
  • GC0XP149081
  • GC0XP150161
  • GC0XP151040
  • GC0XP151031
  • GC0XP152093
  • GC0XP152252
  • GC0XP152599
  • GC0XP141258

Summaries for ZNF275 Gene

Entrez Gene Summary for ZNF275 Gene

  • This gene encodes a zinc finger protein that appears to be conserved in eutheria. Its function has not yet been established. [provided by RefSeq, Jul 2010]

GeneCards Summary for ZNF275 Gene

ZNF275 (Zinc Finger Protein 275) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF275 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF275 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF275 Gene

Genomics for ZNF275 Gene

Regulatory Elements for ZNF275 Gene

Enhancers for ZNF275 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH153335 0.8 Ensembl ENCODE 19.6 +2.0 2002 1.2 SRF FOSL1 ZNF341 FOS ETV6 ZNF275 LOC105373378
GH0XH153334 0.9 ENCODE 16.6 +0.3 348 1.8 HDAC1 TBP RB1 ARNT ARID4B ZNF76 KLF17 SIN3A GLI4 GLIS2 ZNF275 LOC105373378
GH0XH153381 0.9 FANTOM5 11 +46.0 46004 0.3 HDAC1 PKNOX1 ATF1 NFIB NFRKB ZNF766 GATA2 ELK1 CREM CEBPB ZNF275 GC0XP153357 PNMA6E
GH0XH153380 1.2 Ensembl ENCODE 8.2 +47.7 47675 1.8 HDAC1 PKNOX1 ATF1 FOXA2 RB1 BMI1 ZNF48 RAD21 GLIS2 ZNF302 ZNF275 PNMA6E GC0XP153357
GH0XH153369 0.5 ENCODE 16.6 +36.9 36924 2.5 ZNF589 ZNF175 ATF2 NR2F2 ZNF275 GC0XP153357 PNMA6E
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF275 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF275 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000249534 345 1801 HDAC1 TBP RB1 ARNT KLF17 SIN3A GLI4 GLIS2 EGR1 ZNF366

Genomic Locations for ZNF275 Gene

Genomic Locations for ZNF275 Gene
chrX:153,334,155-153,360,110
(GRCh38/hg38)
Size:
25,956 bases
Orientation:
Plus strand
chrX:152,599,613-152,625,568
(GRCh37/hg19)

Genomic View for ZNF275 Gene

Genes around ZNF275 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF275 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF275 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF275 Gene

Proteins for ZNF275 Gene

  • Protein details for ZNF275 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NSD4-ZN275_HUMAN
    Recommended name:
    Zinc finger protein 275
    Protein Accession:
    Q9NSD4
    Secondary Accessions:
    • A6NE92

    Protein attributes for ZNF275 Gene

    Size:
    429 amino acids
    Molecular mass:
    48443 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF275 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF275 Gene

Post-translational modifications for ZNF275 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF275 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF275 Gene

Domains & Families for ZNF275 Gene

Gene Families for ZNF275 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF275 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9NSD4

UniProtKB/Swiss-Prot:

ZN275_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF275: view

Function for ZNF275 Gene

Molecular function for ZNF275 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF275 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF275: view
genes like me logo Genes that share phenotypes with ZNF275: view

Animal Models for ZNF275 Gene

MGI Knock Outs for ZNF275:

Animal Model Products

miRNA for ZNF275 Gene

miRTarBase miRNAs that target ZNF275

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ZNF275 Gene

Localization for ZNF275 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF275 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF275 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF275 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF275: view

Pathways & Interactions for ZNF275 Gene

SuperPathways for ZNF275 Gene

No Data Available

Interacting Proteins for ZNF275 Gene

Gene Ontology (GO) - Biological Process for ZNF275 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF275: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF275 Gene

Drugs & Compounds for ZNF275 Gene

No Compound Related Data Available

Transcripts for ZNF275 Gene

mRNA/cDNA for ZNF275 Gene

Unigene Clusters for ZNF275 Gene

Zinc finger protein 275:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF275 Gene

ExUns: 1 ^ 2 ^ 3a · 3b
SP1:
SP2:

Relevant External Links for ZNF275 Gene

GeneLoc Exon Structure for
ZNF275
ECgene alternative splicing isoforms for
ZNF275

Expression for ZNF275 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF275 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF275 Gene

This gene is overexpressed in Adrenal Gland (x8.3).

Protein differential expression in normal tissues from HIPED for ZNF275 Gene

This gene is overexpressed in Bone (66.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF275 Gene



Protein tissue co-expression partners for ZNF275 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF275 Gene:

ZNF275

SOURCE GeneReport for Unigene cluster for ZNF275 Gene:

Hs.348963
genes like me logo Genes that share expression patterns with ZNF275: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF275 Gene

Orthologs for ZNF275 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF275 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF275 33 34
  • 99.59 (n)
mouse
(Mus musculus)
Mammalia Zfp275 33 16 34
  • 85.7 (n)
cow
(Bos Taurus)
Mammalia ZNF275 33
  • 85.36 (n)
rat
(Rattus norvegicus)
Mammalia Zfp275 33
  • 85.17 (n)
dog
(Canis familiaris)
Mammalia ZNF275 33 34
  • 82.53 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10959 35
  • 37 (a)
worm
(Caenorhabditis elegans)
Secernentea F35H8.3 35
  • 36 (a)
Species where no ortholog for ZNF275 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for ZNF275 Gene

ENSEMBL:
Gene Tree for ZNF275 (if available)
TreeFam:
Gene Tree for ZNF275 (if available)

Paralogs for ZNF275 Gene

(491) SIMAP similar genes for ZNF275 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF275: view

No data available for Paralogs for ZNF275 Gene

Variants for ZNF275 Gene

Sequence variations from dbSNP and Humsavar for ZNF275 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000474864 -- 153,343,204(+) TGGAA(C/G)TTTCT intron-variant
rs1000527425 -- 153,343,517(+) TTTCT(C/T)TGAGG intron-variant
rs1000687346 -- 153,334,423(+) TGCAG(A/G)ACTGT intron-variant
rs1000769373 -- 153,351,848(+) ACAGC(A/G)CCTGC upstream-variant-2KB, utr-variant-3-prime
rs1001568772 -- 153,352,649(+) ACAAT(A/G)GCTAT intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF275 Gene

Variant ID Type Subtype PubMed ID
nsv481629 CNV novel sequence insertion 20440878
nsv481604 CNV novel sequence insertion 20440878
nsv481055 CNV novel sequence insertion 20440878
nsv480571 CNV novel sequence insertion 20440878
nsv480323 CNV novel sequence insertion 20440878
nsv480110 CNV novel sequence insertion 20440878
nsv472361 CNV novel sequence insertion 20440878
esv3575021 CNV loss 25503493
esv33199 CNV gain+loss 17666407
esv2740627 CNV deletion 23290073
esv2740626 CNV deletion 23290073

Variation tolerance for ZNF275 Gene

Gene Damage Index Score: 0.43; 9.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF275 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF275

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF275 Gene

Disorders for ZNF275 Gene

Relevant External Links for ZNF275

Genetic Association Database (GAD)
ZNF275
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF275

No disorders were found for ZNF275 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF275 Gene

Publications for ZNF275 Gene

  1. Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. (PMID: 10854409) Mallon AM … Brown SD (Genome research 2000) 3 4 60
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  3. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H … Mohammed S (Journal of proteome research 2013) 4 60
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L … Andersson-Svahn H (Molecular & cellular proteomics : MCP 2008) 3 60
  5. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PMID: 17903292) Hwang SJ … Fox CS (BMC medical genetics 2007) 45 60

Products for ZNF275 Gene

Sources for ZNF275 Gene

Content
Loading form....