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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF274 Gene

protein-coding   GIFtS: 56
GCID: GC19P058695

zinc finger protein 274
 Explore 2 diseases affiliated with
ZNF274 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ZNF274    

Aliases
for ZNF274 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Zinc Finger Protein 2741 2 3     HFB1012
ZKSCAN191 2 3     ZF22
ZSCAN511 2     KRAB Zinc Finger Protein HFB1012
Zinc Finger Protein HFB1012 3     Neurotrophin Receptor-Interacting Factor Homolog2
Zinc Finger Protein With KRAB And SCAN Domains 192 3     Zf23
Zinc Finger Protein Zfp22 3     

External Ids:    HGNC: 130681   Entrez Gene: 107822   Ensembl: ENSG000001716067   OMIM: 6054675   UniProtKB: Q96GC63   

Export aliases for ZNF274 gene to outside databases

Previous GC identifers: GC19P059592 GC19P059148 GC19P063370 GC19P063386 GC19P055004


Summaries
for ZNF274 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ZNF274:
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated
box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional
repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different
isoforms exist. These variants utilize alternative polyadenylation signals. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ZN274_HUMAN, Q96GC6
Function: Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting
chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression

Gene Wiki entry for ZNF274


Genomic Views
for ZNF274 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF274 gene promoter:
         Egr-3   Spz1   NRF-2   Egr-1   IRF-7A   Hand1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF274 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF274

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF274


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19qter   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.43

ZNF274 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF274 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P058695:  view genomic region     (about GC identifiers)

Start:
 58,694,396 bp from pter      End:
 58,724,927 bp from pter
Size:
 30,532 bases      Orientation:
 plus strand

Proteins
for ZNF274 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ZN274_HUMAN, Q96GC6 (See protein sequence)
Recommended Name: Neurotrophin receptor-interacting factor homolog  
Size: 653 amino acids; 74177 Da
Subunit: Interacts with SETDB1 and TRIM28/KAP1
Subcellular location: Cytoplasm (By similarity). Nucleus, nucleolus
Secondary accessions: Q53XU4 Q6MZG1 Q8WY37 Q8WY38 Q92969 Q9UII0 Q9UII1
Alternative splicing: 4 isoforms:  Q96GC6-1   Q96GC6-2   Q96GC6-3   Q96GC6-4   

Explore the universe of human proteins at neXtProt for ZNF274: NX_Q96GC6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96GC6

    • ZNF274 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_057408.2  NP_057409.1  NP_598009.1  

    ENSEMBL proteins: 
     ENSP00000321209   ENSP00000321187   ENSP00000409872  
    Reactome Protein details: Q96GC6
    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: ZNF274
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    Novus Biologicals ZNF274 Proteins
    Novus Biologicals ZNF274 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ZNF274

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--


    ZNF274 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ZNF274

    Protein Domains /
    Families
    for ZNF274 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ZNF274 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR015880 Znf_C2H2-like
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q96GC6

    ProtoNet protein and cluster: Q96GC6

    3 Blocks protein families:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN274_HUMAN, Q96GC6
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 5 C2H2-type zinc fingers
    Similarity: Contains 2 KRAB domains
    Similarity: Contains 1 SCAN box domain


    Function
    for ZNF274 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ZN274_HUMAN, Q96GC6
    Function: Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting
    chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF274
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF274:
    hsa-miR-152 hsa-miR-148b hsa-miR-23b hsa-miR-2355-3p hsa-miR-130a* hsa-miR-23a hsa-miR-23c hsa-miR-148a
    SwitchGear 3'UTR luciferase reporter plasmid: ZNF274 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF274 (see all 7)
    OriGene shRNA RFP: ZNF274
    OriGene siRNA: ZNF274
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF274

    Gene Editing
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF274 (see all 5)
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    Search LifeMap BioReagents cell lines for ZNF274

    In Situ Assay
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0003714transcription corepressor activity TAS10777669
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0043565sequence-specific DNA binding IDA--


    ZNF274 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for ZNF274:
     Increased G2M DNA content  Increased number of mitotic ce 

    Animal Models:
         Mouse knock-out Zfp110tm1Mpin for ZNF274
         8 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Zfp110):
     cellular  embryogenesis  endocrine/exocrine gland  growth/size  mortality/aging 
     normal  reproductive system  vision/eye 

    ZNF274 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ZNF274 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Generic Transcription Pathway
    		Generic Transcription Pathway1.00
    		Gene Expression0.46
    2p75(NTR)-mediated signaling
    		p75(NTR)-mediated signaling1.00
    3Development HGF signaling pathway
    		Neurotrophin signaling pathway0.20

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for ZNF274 
        p75(NTR)-mediated signaling

    2        Reactome Pathways for ZNF274
        Generic Transcription Pathway
    Gene Expression


    1         Kegg Pathway  (Kegg details for ZNF274):
        Neurotrophin signaling pathway


    ZNF274 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF274

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/21 Interacting proteins for ZNF274 (Q96GC63 ENSP000004098724) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NGFRP081383, ENSP000001722294I2D: score=2 STRING: ENSP00000172229
    SETDB1Q150473, ENSP000003579654I2D: score=1 STRING: ENSP00000357965
    TRIM28Q132633, ENSP000002530244I2D: score=1 STRING: ENSP00000253024
    GRB2P629933, ENSP000003390074I2D: score=1 STRING: ENSP00000339007
    PCBD1P614573I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent TAS10520746
    GO:0016032viral reproduction IEA--


    ZNF274 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ZNF274 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF274
    Search CenterWatch for drugs/clinical trials and news about ZNF274 / ZN274 

    Transcripts
    for ZNF274 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ZNF274 gene (3 alternative transcripts): 
    NM_016324.2  NM_016325.2  NM_133502.1  

    Unigene Cluster for ZNF274:

    Zinc finger protein 274
    Hs.83761  [show with all ESTs]
    Unigene Representative Sequence: AK095162
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000326804(uc010yhu.1 uc002qrq.1 uc010eum.1) ENST00000345813(uc002qrr.1)
    ENST00000424679(uc010yhv.1 uc002qrs.1)

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF274:
    hsa-miR-152 hsa-miR-148b hsa-miR-23b hsa-miR-2355-3p hsa-miR-130a* hsa-miR-23a hsa-miR-23c hsa-miR-148a
    SwitchGear 3'UTR luciferase reporter plasmid: ZNF274 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF274 (see all 7)
    OriGene shRNA RFP: ZNF274
    OriGene siRNA: ZNF274
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF274
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 3): ZNF274 (NM_016324)
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF274

    Additional cDNA sequence: 

    AB029149.1 AB029150.1 AF275680.1 AF275681.1 AK095162.1 AK222855.1 AK222878.1 AK295036.1 
    AK296929.1 AK297466.1 AK307906.1 AK316429.1 BC009763.2 BT007304.1 U71598.1 

    8 DOTS entries:

    DT.97819509  DT.97840915  DT.100757673  DT.97762423  DT.91646384  DT.102829037  DT.121505617  DT.121505616 

    24/110 AceView cDNA sequences (see all 110):

    CA867240 AL547967 CB136752 BM972736 BM998445 AB029150 BM725165 BQ896639 
    CA419663 CA867052 AA001944 BC009763 CB145499 CK822710 BI916897 NM_016325 
    NM_133502 AL545003 NM_016324 BQ016359 CA867161 BQ574715 BU683158 AA662917 

    GeneLoc Exon Structure


    Expression
    for ZNF274 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF274 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACAGGCCTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ZNF274 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbLimb BudLimb Bud Mesenchyme CellsMesoderm
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ZNF274 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF274

    SOURCE GeneReport for Unigene cluster: Hs.83761
        SABiosciences Custom PCR Arrays for ZNF274
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF274

    Orthologs
    for ZNF274 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF274 gene from 2/5 species (see all 5)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Zfp1105 zinc finger protein 110   --   7 (7.66 cM) 12834761 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 9)    		 --
    		 40(a)
    37(a)
    (see all 9)    		 many ↔ many
    many ↔ many
    (see all 9)    		 AAWZ02040759(388-6051)
    GL344256.1(48097-50057)


    ENSEMBL Gene Tree for ZNF274 (if available)
    TreeFam Gene Tree for ZNF274 (if available) 

    Paralogs
    for ZNF274 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF274 gene
    ZSCAN182  ZNF2152  ZSCAN12  ZNF4832  
    18/75 SIMAP similar genes for ZNF274 using alignment to 3 protein entries:     ZN274_HUMAN (see all proteins) (see all similar genes):
    ZNF433    ZNF697    ZNF250    ZNF    ZNF493    ZNF660
    ZNF71    ZNF844    GFI1B    GLI4    ZNF260    ZNF702P
    ZNF664    ZNF323    ZNF501    ZNF137P    ZNF578    ZNF589

    ZNF274 for paralogs           About GeneDecksing



    Genomic Variants
    for ZNF274 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/38 NCBI SNPs in ZNF274 are shown (see all 38)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs725251431,2
    		C--55005944(+) AGGTC-/TTTTG 
                TTTGT     		3 -- int10--------
    rs1503513311,2
    		--58695649(+) AGGTC-/TTTTG 
                TTTGT     		1 -- int10--------
    rs339298291,2
    		C--58697544(+) CTATT-/AAAAAA 1 -- int11Minor allele frequency- A:0.00NA 2
    rs2009821361,2
    		--58700025(+) ATAGA-/TGTGTGT 3 -- int10--------
    rs112870511,2
    		C,--58700252(+) AAAAA-/ATTAAA 1 -- int1 trp32Minor allele frequency- A:0.00NA CSA 4
    rs1503689471,2
    		--58706028(+) CAGGTA/GTGAGC 1 -- int10--------
    rs1998060121,2
    		--58706101(+) CGGGC-/GCGGTGGC 1 -- int10--------
    rs2019927601,2
    		--58706106(+) GCGGT-/GGCTGATG 1 -- int10--------
    rs72577721,2
    		H--58706161(+) cctgaG/Aaagtt 1 -- int14Minor allele frequency- A:0.00NS EA 412
    rs621259141,2
    		C,--58706186(+) CTAACA/TCGGAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for ZNF274 (58694396 - 58724927 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ZNF274: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF274
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF274

    Disorders / Diseases
    for ZNF274 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ZNF274 for disorders           About GeneDecksing

    OMIM gene information: 605467    OMIM disorders: --

    2 diseases for ZNF274:    About MalaCards
    denys-drash syndrome    frasier syndrome

    1 disease from the University of Copenhagen DISEASES database for ZNF274:
    Denys-Drash syndrome

    Export disorders for ZNF274 gene to outside databases

    Publications
    for ZNF274 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF274 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with ZNF274)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human ZNF274 cDNA, Which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting ability. (PubMed id 10777669)1, 2, 3, 9 Yano K.... Muramatsu M. (2000)
    2. ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. (PubMed id 21170338)1, 2 Frietze S.... Farnham P.J. (2010)
    3. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Computer sequence analysis of human highly conserved zinc finger modules. (PubMed id 10520746)1, 2 Petroni D.... Comi P. (1998)
    6. Human POGZ modulates dissociation of HP1alpha from mi totic chromosome arms through Aurora B activation. (PubMed id 20562864)1 Nozawa R.S....Obuse C. (2010)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain. (PubMed id 17512541)1 Peng H....Rauscher F.J. (2007)
    9. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    External Searches for ZNF274 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing ZNF274 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10782 HGNC: 13068 AceView: ZNF274 Ensembl:ENSG00000171606 euGenes: HUgn10782
    ECgene: ZNF274 Kegg: 10782 H-InvDB: ZNF274

    Other Databases showing ZNF274 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ZNF274 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF274 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ZNF274 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ZNF274 gene:
    Search GeneIP for patents involving ZNF274

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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