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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF274 Gene

protein-coding   GIFtS: 57
GCID: GC19P058695

Zinc Finger Protein 274

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 2741 2 3     ZF22
Zinc Finger Protein HFB1012 3     ZSCAN512
Zinc Finger Protein With KRAB And SCAN Domains 192 3     KRAB Zinc Finger Protein HFB1012
Zinc Finger Protein Zfp22 3     Neurotrophin Receptor-Interacting Factor Homolog2
ZKSCAN192 3     Zf23
HFB1012     

External Ids:    HGNC: 130681   Entrez Gene: 107822   Ensembl: ENSG000001716067   OMIM: 6054675   UniProtKB: Q96GC63   

Export aliases for ZNF274 gene to outside databases

Previous GC identifers: GC19P059592 GC19P059148 GC19P063370 GC19P063386 GC19P055004


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ZNF274 Gene:
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two
Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to
be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript
variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. (provided
by RefSeq, Jul 2008)

GeneCards Summary for ZNF274 Gene: 
ZNF274 (zinc finger protein 274) is a protein-coding gene. Diseases associated with ZNF274 include frasier syndrome, and denys-drash syndrome, and among its related super-pathways are Gene Expression and Development Neurotrophin family signaling. GO annotations related to this gene include transcription corepressor activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZSCAN18.

UniProtKB/Swiss-Prot: ZN274_HUMAN, Q96GC6
Function: Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and
recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression

Gene Wiki entry for ZNF274 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF274 gene promoter:
         Egr-3   Spz1   NRF-2   Egr-1   IRF-7A   Hand1   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF274 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF274

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF274


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19qter   Ensembl cytogenetic band:  19q13.43   HGNC cytogenetic band: 19q13.43

ZNF274 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF274 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P058695:  view genomic region     (about GC identifiers)

Start:
58,694,396 bp from pter      End:
58,724,928 bp from pter
Size:
30,533 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZN274_HUMAN, Q96GC6 (See protein sequence)
Recommended Name: Neurotrophin receptor-interacting factor homolog  
Size: 653 amino acids; 74177 Da
Subunit: Interacts with SETDB1 and TRIM28/KAP1
Subcellular location: Cytoplasm (By similarity). Nucleus, nucleolus
Secondary accessions: Q53XU4 Q6MZG1 Q8WY37 Q8WY38 Q92969 Q9UII0 Q9UII1
Alternative splicing: 4 isoforms:  Q96GC6-1   Q96GC6-2   Q96GC6-3   Q96GC6-4   

Explore the universe of human proteins at neXtProt for ZNF274: NX_Q96GC6

Explore proteomics data for ZNF274 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96GC6

  • ZNF274 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZNF274 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001265663.1  NP_001265664.1  NP_057408.2  NP_057409.1  NP_598009.1  

    ENSEMBL proteins: 
     ENSP00000469546   ENSP00000469427   ENSP00000321209   ENSP00000321187   ENSP00000409872  
    Reactome Protein details: Q96GC6
    Human Recombinant Protein Products for ZNF274: 
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    Cloud-Clone Corp. Proteins for ZNF274 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--

    ZNF274 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    5/6 InterPro protein domains (see all 6):
     IPR015880 Znf_C2H2-like
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q96GC6

    ProtoNet protein and cluster: Q96GC6

    3 Blocks protein domains:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN274_HUMAN, Q96GC6
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 5 C2H2-type zinc fingers
    Similarity: Contains 2 KRAB domains
    Similarity: Contains 1 SCAN box domain


    ZNF274 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN274_HUMAN, Q96GC6
    Function: Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and
    recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0003714transcription corepressor activity TAS10777669
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding ----
         
    ZNF274 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ZNF274:
     Increased G2M DNA content  Increased number of mitotic ce 

         8 MGI mutant phenotypes (inferred from 1 allele(MGI details for Zfp110):
     cellular  embryogenesis  endocrine/exocrine gland  growth/size  mortality/aging 
     normal  reproductive system  vision/eye 

    ZNF274 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Zfp110tm1Mpin for ZNF274

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZNF274 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZNF274

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    SwitchGear 3'UTR luciferase reporter plasmidZNF274 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ZNF274 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Generic Transcription Pathway
    Gene Expression0.47
    Generic Transcription Pathway0.47
    2Development HGF signaling pathway
    Neurotrophin signaling pathway0.36
    3p75(NTR)-mediated signaling
    p75(NTR)-mediated signaling

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for ZNF274
        p75(NTR)-mediated signaling

    2        Reactome Pathways for ZNF274
        Generic Transcription Pathway
    Gene Expression


    1         Kegg Pathway  (Kegg details for ZNF274):
        Neurotrophin signaling pathway


    ZNF274 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF274

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/21 Interacting proteins for ZNF274 (Q96GC63 ENSP000004098724) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NGFRP081383, ENSP000001722294I2D: score=2 STRING: ENSP00000172229
    SETDB1Q150473, ENSP000003579654I2D: score=1 STRING: ENSP00000357965
    TRIM28Q132633, ENSP000002530244I2D: score=1 STRING: ENSP00000253024
    GRB2P629933, ENSP000003390074I2D: score=1 STRING: ENSP00000339007
    PCBD1P614573I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent TAS10520746
    GO:0016032viral process ----

    ZNF274 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF274 (ZN274)

    Search CenterWatch for drugs/clinical trials and news about ZNF274 / ZN274

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF274 gene (5 alternative transcripts): 
    NM_001278734.1  NM_001278735.1  NM_016324.3  NM_016325.3  NM_133502.2  

    Unigene Cluster for ZNF274:

    Zinc finger protein 274
    Hs.83761  [show with all ESTs]
    Unigene Representative Sequence: AK095162
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000599438 ENST00000599081 ENST00000600704 ENST00000601777 ENST00000601156
    ENST00000594248 ENST00000598143 ENST00000597818 ENST00000597528 ENST00000594839
    ENST00000595772 ENST00000601995 ENST00000595146 ENST00000326804(uc010yhu.1 uc002qrq.1 uc010eum.1)
    ENST00000345813(uc002qrr.1) ENST00000424679(uc010yhv.1 uc002qrs.1)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    hsa-miR-152 hsa-miR-148b hsa-miR-23b hsa-miR-2355-3p hsa-miR-130a* hsa-miR-23a hsa-miR-23c hsa-miR-148a
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    Additional mRNA sequence: 

    AB029149.1 AB029150.1 AF275680.1 AF275681.1 AK095162.1 AK222855.1 AK222878.1 AK295036.1 
    AK296929.1 AK297466.1 AK307906.1 AK316429.1 BC009763.2 BT007304.1 U71598.1 

    8 DOTS entries:

    DT.97819509  DT.97840915  DT.100757673  DT.97762423  DT.91646384  DT.102829037  DT.121505617  DT.121505616 

    24/110 AceView cDNA sequences (see all 110):

    CA867240 BM972736 AA001944 BQ574715 BU683158 CA419663 BM998445 BM144675 
    BC009763 CB145499 CA867161 BQ896639 CK822710 AB029150 CA867052 BQ016325 
    BM725165 AL545003 NM_016324 CA942455 NM_016325 BQ016359 AA662917 BI916897 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF274 expression in normal human tissues (normalized intensities)      ZNF274 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACAGGCCTG
    ZNF274 Expression
    About this image


    ZNF274 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Limb (Muscoskeletal System)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Liver (Hepatobiliary System)
             Periportal Hepatocytes Liver Lobule
     
     Mesoderm (Gastrulation Derivatives)
             Limb Bud Mesenchyme Cells Limb Bud
     
     Thymus (Hematopoietic System)

    See ZNF274 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF274

    SOURCE GeneReport for Unigene cluster: Hs.83761
        SABiosciences Custom PCR Arrays for ZNF274
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZNF274 gene from 1/4 species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp1105 zinc finger protein 110   --   7 (7.66 cM) 12834761 


    ENSEMBL Gene Tree for ZNF274 (if available)
    TreeFam Gene Tree for ZNF274 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF274 gene
    ZSCAN182  ZNF2152  ZSCAN12  ZIM22  
    18/258 SIMAP similar genes for ZNF274 using alignment to 3 protein entries:     ZN274_HUMAN (see all proteins) (see all similar genes):
    ZNF788    ZNF763    ZNF418    ZNF700    ZNF791    ZNF878
    ZNF718    ZNF66    ZNF234    ZNF519    ZNF562    ZNF669
    ZNF28    ZNF320    ZNF525    ZNF776    ZNF845    ZNF888

    ZNF274 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/622 SNPs in ZNF274 are shown (see all 622)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs795997341,2
    C,F--55002807(+) AAAGAA/GATCAT 3 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1810854911,2
    --55002813(+) ATCATC/TAGAAG 3 -- us2k10--------
    rs1425363721,2
    --55002845(+) CATAGA/TGAGGT 3 -- us2k10--------
    rs1859248111,2
    --55002861(+) TCTCTA/TCAAAA 3 -- us2k10--------
    rs1509289701,2
    --55002887(+) CAGGCA/GGGGTG 3 -- us2k10--------
    rs1573551,2
    C,F--55002981(-) gtttcA/Tccatg 3 -- us2k14Minor allele frequency- T:0.12NA WA CSA 8
    rs1893063141,2
    --55002990(+) ACCCCA/GTCTCT 3 -- us2k10--------
    rs1448982091,2
    --55003210(+) TATTTC/GAGAGG 3 -- us2k10--------
    rs1162720221,2
    F--55003292(+) AGTCGG/AGGTGA 3 -- us2k11Minor allele frequency- A:0.01WA 118
    rs778573521,2
    C,F--55003545(+) TGGTGT/GTGTAT 3 -- us2k11Minor allele frequency- G:0.03WA 118

    HapMap Linkage Disequilibrium report for ZNF274 (58694396 - 58724928 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ZNF274:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv912537CNV Loss21882294
    nsv833886CNV Gain17160897
    nsv912536CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605467    OMIM disorders: --

    2 diseases for ZNF274:    About MalaCards
    frasier syndrome    denys-drash syndrome

    1 disease from the University of Copenhagen DISEASES database for ZNF274:
    Denys-Drash syndrome

    ZNF274 for disorders           About GeneDecksing


    Export disorders for ZNF274 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF274 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with ZNF274)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of human ZNF274 cDNA, Which encodes a novel kruppel-type zinc-finger protein having nucleolar targeting ability. (PubMed id 10777669)1, 2, 3, 9 Yano K.... Muramatsu M. (2000)
    2. ZNF274 recruits the histone methyltransferase SETDB1 to the 3' ends of ZNF genes. (PubMed id 21170338)1, 2 Frietze S.... Farnham P.J. (2010)
    3. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Computer sequence analysis of human highly conserved zinc finger modules. (PubMed id 10520746)1, 2 Petroni D.... Comi P. (1998)
    6. Human POGZ modulates dissociation of HP1alpha from mi totic chromosome arms through Aurora B activation. (PubMed id 20562864)1 Nozawa R.S....Obuse C. (2010)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. The structurally disordered KRAB repression domain is incorporated into a protease resistant core upon binding to KAP-1-RBCC domain. (PubMed id 17512541)1 Peng H....Rauscher F.J. (2007)
    9. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10782 HGNC: 13068 AceView: ZNF274 Ensembl:ENSG00000171606 euGenes: HUgn10782
    ECgene: ZNF274 Kegg: 10782 H-InvDB: ZNF274

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF274 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF274 gene:
    Search GeneIP for patents involving ZNF274

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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