ZNF271 Gene
pseudogene GIFtS: 43
GCID: GC18P032871
|
|
zinc finger protein 271
| |
Aliases
for ZNF271 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Zinc Finger Protein 2711 2 | | EBV-Induced Zinc Finger Protein3 | | ZNFEB1 2 3 5 | | Epstein-Barr Virus-Induced Zinc Finger Protein3 | | HZF71 2 | | Zinc Finger Protein Dp3 | | CT-ZFP483 | | Zinc Finger Protein HZF73 | | ZNF-EB3 | | Zinc Finger Protein ZNFphex1333 | | ZNF-Dp1 | | |
| External Ids: | HGNC: 130651 | Entrez Gene: 107782 | Ensembl: ENSG000002572677 | OMIM: 6047545 | UniProtKB: Q145913 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n407071 | |
Export aliases for ZNF271 gene to outside databasesPrevious GC identifers: GC18P032904 GC18P032689 GC18P031123 GC18P031124 GC18P029729
Summaries
for ZNF271 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZNF271:
Zinc finger proteins interact with nucleic acids and have diverse functions. The zinc finger domain is a conservedamino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved incoordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) foradditional information on zinc finger proteins.(supplied by OMIM, Apr 2004)
UniProtKB/Swiss-Prot: ZN271_HUMAN, Q14591Function: May be involved in transcriptional regulation. Plays a role in the EBV-mediated transformation process
|
Genomic Views
for ZNF271 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000018.9 NC_018929.1 NT_010966.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF271 gene promoter:
POU2F1 POU2F1b POU2F1a POU2F1c Pax-4a Zic3
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF271
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF271 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 18q12 Ensembl cytogenetic band: 18q12.2 HGNC cytogenetic band: 18q12.2ZNF271 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 18 GeneLoc Exon Structure GeneLoc location for GC18P032871: view genomic region
(about GC identifiers)
Start:
|
32,870,236 bp from pter |
End:
|
32,890,730 bp from pter |
Size:
|
20,495 bases |
Orientation:
|
plus strand |
|
Proteins
for ZNF271 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN271_HUMAN, Q14591 (See
protein sequence)Recommended Name: Zinc finger protein 271 Size: 655 amino acids; 75535 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=AAK52068.1; Type=Frameshift; Positions=481;
Secondary accessions: B3KN34 Q96T29 Q9BSX2 Q9UN33 Q9Y5B7Alternative splicing: 2 isoforms: Q14591-1 Q14591-2 Explore the universe of human proteins at neXtProt for ZNF271: NX_Q14591
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14591
ZNF271 Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products:
ZNF271 Antibody Products:
Assay Products for ZNF271: |
Protein
Domains /
Families
for ZNF271 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF271 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q14591ProtoNet protein and cluster: Q14591 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN271_HUMAN, Q14591Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 19 C2H2-type zinc fingers |
Function
for ZNF271 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN271_HUMAN, Q14591Function: May be involved in transcriptional regulation. Plays a role in the EBV-mediated transformation processInduction: By Epstein-Barr virus (EBV)
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF271 |
1 GenomeRNAi human phenotype for ZNF271:
|
Pathways & Interactions
for ZNF271 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF271
1 Interacting protein for ZNF271 (Q145912) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ZNF271 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF271
Search CenterWatch for drugs/clinical trials and news about ZNF271 
|
Transcripts
for ZNF271 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF271 gene: NM_006629.4 Unigene Cluster for ZNF271: Zinc finger protein 271 Hs.314246 [show with all ESTs]Unigene Representative Sequence: NR_0245653 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000399070(uc002kyq.4 uc002kyp.4 uc002kyr.4) ENST00000465539
ENST00000540308
Additional cDNA sequence: AF159567.1 AK023456.1 BC004510.2 BC017710.1 NR_024565.1 NR_024566.1 X78930.1 10 DOTS entries: DT.100745242 DT.100745243 DT.211237 DT.308394 DT.95148423 DT.99927883 DT.100711296 DT.102830817 DT.100773958 DT.99936362 24/94 AceView cDNA sequences (see all 94): AA383181 BX118808 BC017710 CA447662 AI370593 Z39393 F07427 CB128123 AA464946 BC004510 AU135134 BF196039 AU116866 F08646 AK094216 BE747828 BG027202 BU622521 F02743 CK003080 AK023456 F03658 AA833516 CD701172
GeneLoc Exon Structure
|
Expression
for ZNF271 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF271 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGATGAGTGT
About this image
Genevestigator expression for ZNF271
SOURCE GeneReport for Unigene cluster: Hs.314246
UniProtKB/Swiss-Prot: ZN271_HUMAN, Q14591Tissue specificity: Expressed in T-cell lines, thymocytes, thyroid and pancreatic islet cells
SABiosciences Custom PCR Arrays for ZNF271
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF271
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF271 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF271 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF271 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF271 |
Orthologs
for ZNF271 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF271 gene from 1/2 species (see all 2) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
BX763356.12 |
-- |
68.93(n) |
|
BX763356.1 |
Species with no ortholog for ZNF271
ENSEMBL Gene Tree for ZNF271 (if available)
TreeFam Gene Tree for ZNF271 (if available) |
Paralogs
for ZNF271 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ZNF271 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 18 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF271 (32870236 - 32890730 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF271: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ZNF271 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF271 for disorders About GeneDecksing
OMIM gene information: 604754
OMIM disorders: --
2  diseases for ZNF271: About MalaCardsthyroiditis pancreatitis
Export disorders for ZNF271 gene to outside databases
|
Publications
for ZNF271 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF271 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF271) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Sustained expression of the novel EBV-induced zinc finger gene, ZNF- EB, is critical for the transition of B lymphocyte activation to oncogenic growth transformation. (PubMed id 11777961)1, 2, 3, 9 Tune C.E.... Dosch H.-M. (2002)
- Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PubMed id 7865130)1, 2, 3 Abrink M.... Hellman L. (1995)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for ZNF271 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF271 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF271 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF271 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ZNF271 gene:
Search GeneIP for patents involving ZNF271
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF271 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF271 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF271 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF271 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF271 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF271 | | Browse OriGene Myc/DDK tagged cDNA clones in CMV expression vector | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF271 | | OriGene Custom Protein Services for ZNF271 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF271 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF271 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF271 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF271 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF271 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF271 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF271 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF271 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF271 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF271 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF271 |
|
|
|
|
GeneCards Homepage -
Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
View Random Gene
|
Category
|
|
|
von Willebrand factor
|
| GIFtS Group |
|
Developed at the Crown Human Genome Center,
Department of Molecular Genetics,
the Weizmann Institute of Science
Copyright © 1996-2013
, Weizmann Institute of Science. All Rights Reserved.
hostname: 356977-web1.xennexinc.com
index build: 100 solr: 1.4
|
