Aliases for ZNF268 Gene
External Ids for ZNF268 Gene
Previous GeneCards Identifiers for ZNF268 Gene
GeneCards Summary for ZNF268 Gene
ZNF268 (Zinc Finger Protein 268) is a Protein Coding gene. Diseases associated with ZNF268 include Ovarian Cancer and Chronic Lymphocytic Leukemia. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF182.
UniProtKB/Swiss-Prot for ZNF268 Gene
Isoform 1: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression.
Isoform 2: Contributes to cervical carcinogenesis in part through the TNF-alpha-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.