ZNF264 Gene
protein-coding GIFtS: 52
GCID: GC19P057702
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|
zinc finger protein 264
| |
Aliases
for ZNF264 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 2641 2 | | KIAA04121 3 |
Export aliases for ZNF264 gene to outside databasesPrevious GC identifers: GC19P058601 GC19P058156 GC19P062378 GC19P062394 GC19P054015 |
Summaries
for ZNF264 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZNF264:
This gene encodes a zinc finger protein and belongs to the krueppel C2H2-type zinc-finger protein family. Zinc fingerproteins are often localized in the nucleus, bind nucleic acids, and regulate transcription. (provided by RefSeq, Jan2010)
UniProtKB/Swiss-Prot: ZN264_HUMAN, O43296Function: May be involved in transcriptional regulation
Gene Wiki entry for ZNF264
|
Genomic Views
for ZNF264 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF264 gene promoter:
GATA-3 POU3F2 (N-Oct-5b) POU3F2 (N-Oct-5a) POU3F2 Meis-1b GATA-1 GATA-2 FAC1 Meis-1a Hlf
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF264
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF264 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.4 Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19q13.4ZNF264 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P057702: view genomic region
(about GC identifiers)
Start:
|
57,702,868 bp from pter |
End:
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57,734,214 bp from pter |
Size:
|
31,347 bases |
Orientation:
|
plus strand |
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Proteins
for ZNF264 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN264_HUMAN, O43296 (See
protein sequence)Recommended Name: Zinc finger protein 264 Size: 627 amino acids; 70587 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAA24842.2; Type=Erroneous initiation;
Secondary accessions: A8K8Y9 Q9P1V0Explore the universe of human proteins at neXtProt for ZNF264: NX_O43296
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O43296
ZNF264 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003408.1
ENSEMBL proteins: ENSP00000263095 ENSP00000440376 Reactome Protein details: O43296
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF264 for ontologies About GeneDecksing
ZNF264 Antibody Products:
Assay Products for ZNF264: |
Protein
Domains /
Families
for ZNF264 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF264 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O43296ProtoNet protein and cluster: O43296 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN264_HUMAN, O43296Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 13 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF264 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN264_HUMAN, O43296Function: May be involved in transcriptional regulation Genatlas biochemistry entry for ZNF264:Kruppel-related zinc finger protein 264 ,Kruppel related
Clone
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF264 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF264 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF264 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF264
ZNF264 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF264
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for ZNF264 (ENSP000002630954) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF264 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF264 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF264
Search CenterWatch for drugs/clinical trials and news about ZNF264 / ZN264
|
Transcripts
for ZNF264 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF264 gene: NM_003417.4 Unigene Cluster for ZNF264: Zinc finger protein 264 Hs.515634 [show with all ESTs]Unigene Representative Sequence: NM_0034172 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000263095(uc002qob.3) ENST00000536056
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF264
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF264
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF264 (NM_003417) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF264 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF264 |
Additional cDNA sequence: AB007872.1 AK097167.1 AK292504.1 BC115410.2 BC115411.1 7 DOTS entries: DT.114318 DT.121500227 DT.92419769 DT.121500241 DT.102824483 DT.95139047 DT.95134105 24/105 AceView cDNA sequences (see all 105): BM693525 F02246 N50396 BQ020432 BU619664 BQ575361 AW976429 BM821845 BP354221 Z42777 AA761789 AL047747 BG288543 BF431294 BX953745 AA057422 AK097167 AI912679 BG250485 H86268 CA314253 AL699268 CK825398 BM989779
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF264 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
|---|
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| SP1: | | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | - | | - | | - | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF264
|
Expression
for ZNF264 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF264 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTTCAGTGG
About this image
See ZNF264 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF264
SOURCE GeneReport for Unigene cluster: Hs.515634
UniProtKB/Swiss-Prot: ZN264_HUMAN, O43296Tissue specificity: Relatively highly expressed in kidney, thymus, testis, ovary, brain, lung, placenta, and prostate,and relatively low expression in heart, liver, skeletal muscle, pancreas, spleen, and small intestine
SABiosciences Custom PCR Arrays for ZNF264
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF264
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF264 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF264 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF264 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF264 |
Orthologs
for ZNF264 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF264 (if available)
TreeFam Gene Tree for ZNF264 (if available) |
Paralogs
for ZNF264 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF264 gene
- ENSG000002513692 ZNF802 ZNF4602 ZNF5432 ZNF8052 ZNF5992
18/490 SIMAP similar genes for ZNF264 using alignment to 6 protein entries: ZN264_HUMAN (see all proteins)
(see all similar genes):ZNF805 ZNF543 ZNF818P kr-znf3 ZNF78L1 ZFS-4
DKFZp666C237 HZF30 zf30 DKFZp313M0722 HZF16 ZNF323
ZNF550 ZNF578 DKFZp686H10254 HZF36 ZFP41 ZNF146
ZNF264 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF264 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF264 (57702868 - 57734214 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for ZNF264
4 CNVs: 89349 89351 78301 78300
2 Indels: 89350 78302 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF264 |
|
Disorders
/ Diseases
for ZNF264 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF264 for disorders About GeneDecksing
OMIM gene information: 604668
OMIM disorders: --
1  disease for ZNF264: About MalaCardsprostatitis
Export disorders for ZNF264 gene to outside databases
|
Publications
for ZNF264 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF264 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with ZNF264) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9455477)1, 2, 3 Ishikawa K....Ohara O. (1997)
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Wnt signaling and Dupuytren's disease. (PubMed id 21732829)1 Dolmans G.H.... . (2011)
- Human POGZ modulates dissociation of HP1alpha from mi totic chromosome arms through Aurora B activation. (PubMed id 20562864)1 Nozawa R.S....Obuse C. (2010)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)2 Matsuoka S.... Elledge S.J. (2007)
|
External Searches for ZNF264 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF264 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF264 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF264 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF264 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF264 gene:
Search GeneIP for patents involving ZNF264
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF264 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF264 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF264 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF264 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF264 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF264 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF264 |
| |
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| |  |  |  |  | | | | |
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 | | | ZNF264 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF264 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF264 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF264 |
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