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Aliases for ZNF264 Gene

Aliases for ZNF264 Gene

  • Zinc Finger Protein 264 2 3
  • KIAA0412 4

External Ids for ZNF264 Gene

Summaries for ZNF264 Gene

Entrez Gene Summary for ZNF264 Gene

  • This gene encodes a zinc finger protein and belongs to the krueppel C2H2-type zinc-finger protein family. Zinc finger proteins are often localized in the nucleus, bind nucleic acids, and regulate transcription. [provided by RefSeq, Jan 2010]

GeneCards Summary for ZNF264 Gene

ZNF264 (Zinc Finger Protein 264) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF460.

UniProtKB/Swiss-Prot for ZNF264 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF264 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF264 Gene

Genomics for ZNF264 Gene

Genomic Location for ZNF264 Gene

Start:
57,191,480 bp from pter
End:
57,222,846 bp from pter
Size:
31,367 bases
Orientation:
Plus strand

Genomic View for ZNF264 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF264 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF264 Gene

Regulatory Elements for ZNF264 Gene

Proteins for ZNF264 Gene

  • Protein details for ZNF264 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O43296-ZN264_HUMAN
    Recommended name:
    Zinc finger protein 264
    Protein Accession:
    O43296
    Secondary Accessions:
    • A8K8Y9
    • Q9P1V0

    Protein attributes for ZNF264 Gene

    Size:
    627 amino acids
    Molecular mass:
    70587 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA24842.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF264 Gene

Proteomics data for ZNF264 Gene at MOPED

Post-translational modifications for ZNF264 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys481

Other Protein References for ZNF264 Gene

No data available for DME Specific Peptides for ZNF264 Gene

Domains for ZNF264 Gene

Gene Families for ZNF264 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN264_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • O43296
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • O43296
Similarity:
  • Contains 13 C2H2-type zinc fingers.:
    • O43296
genes like me logo Genes that share domains with ZNF264: view

Function for ZNF264 Gene

Molecular function for ZNF264 Gene

GENATLAS Biochemistry: Kruppel-related zinc finger protein 264 ,Kruppel related
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF264: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF264 Gene

Localization for ZNF264 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF264 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF264 Gene COMPARTMENTS Subcellular localization image for ZNF264 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF264: view

Pathways for ZNF264 Gene

SuperPathways for ZNF264 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF264: view

Pathways by source for ZNF264 Gene

2 Reactome pathways for ZNF264 Gene

Interacting Proteins for ZNF264 Gene

Gene Ontology (GO) - Biological Process for ZNF264 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF264: view

Transcripts for ZNF264 Gene

Unigene Clusters for ZNF264 Gene

Zinc finger protein 264:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF264 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b
SP1: -
SP2: - - -
SP3: - -
SP4:

Relevant External Links for ZNF264 Gene

GeneLoc Exon Structure for
ZNF264
ECgene alternative splicing isoforms for
ZNF264

Expression for ZNF264 Gene

mRNA expression in normal human tissues for ZNF264 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF264 Gene

SOURCE GeneReport for Unigene cluster for ZNF264 Gene Hs.515634

mRNA Expression by UniProt/SwissProt for ZNF264 Gene

O43296-ZN264_HUMAN
Tissue specificity: Relatively highly expressed in kidney, thymus, testis, ovary, brain, lung, placenta, and prostate, and relatively low expression in heart, liver, skeletal muscle, pancreas, spleen, and small intestine
genes like me logo Genes that share expressions with ZNF264: view

Orthologs for ZNF264 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF264 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF264 36
  • 99.2 (n)
  • 99.36 (a)
ZNF264 37
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF264 36
  • 85.62 (n)
  • 84.64 (a)
ZNF264 37
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp264 16
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 42 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CU138542.3 37
  • 43 (a)
ManyToMany
si:dkey-7j22.3 37
  • 52 (a)
ManyToMany
Species with no ortholog for ZNF264:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF264 Gene

ENSEMBL:
Gene Tree for ZNF264 (if available)
TreeFam:
Gene Tree for ZNF264 (if available)

Paralogs for ZNF264 Gene

Paralogs for ZNF264 Gene

Selected SIMAP similar genes for ZNF264 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF264: view

Variants for ZNF264 Gene

Sequence variations from dbSNP and Humsavar for ZNF264 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs758096 -- 57,221,817(+) GGGCA(C/G)TGAGC utr-variant-3-prime, nc-transcript-variant
rs917340 - 57,211,645(+) AGTCC(A/G)TAGCC missense, reference, nc-transcript-variant
rs924020 -- 57,193,665(+) TCTAA(C/T)GGCCG intron-variant
rs1129873 -- 57,222,528(+) TCTAT(A/G)TATAT utr-variant-3-prime, nc-transcript-variant
rs1558117 -- 57,202,490(+) CAGGG(A/T)CAGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF264 Gene

Variant ID Type Subtype PubMed ID
esv2662848 CNV Deletion 23128226
esv2663783 CNV Deletion 23128226

Relevant External Links for ZNF264 Gene

HapMap Linkage Disequilibrium report
ZNF264

Disorders for ZNF264 Gene

Relevant External Links for ZNF264

Genetic Association Database (GAD)
ZNF264
genes like me logo Genes that share disorders with ZNF264: view

No data available for UniProtKB/Swiss-Prot for ZNF264 Gene

Publications for ZNF264 Gene

  1. Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. (PMID: 9455477) Ishikawa K. … Ohara O. (DNA Res. 1997) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J. … Comb M.J. (Nat. Biotechnol. 2005) 3 4
  5. Transcriptome analysis of human gastric cancer. (PMID: 16341674) Oh J.H. … Kim N.S. (Mamm. Genome 2005) 3

Products for ZNF264 Gene

Sources for ZNF264 Gene

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