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Aliases for ZNF263 Gene

Aliases for ZNF263 Gene

  • Zinc Finger Protein 263 2 3
  • Zinc Finger Protein With KRAB And SCAN Domains 12 3 4
  • Zinc Finger Protein FPM315 3 4
  • ZKSCAN12 3 4
  • FPM315 3 4
  • ZSCAN44 3

External Ids for ZNF263 Gene

Previous GeneCards Identifiers for ZNF263 Gene

  • GC16P003354
  • GC16P003333
  • GC16P003273
  • GC16P003319

Summaries for ZNF263 Gene

GeneCards Summary for ZNF263 Gene

ZNF263 (Zinc Finger Protein 263) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF202.

UniProtKB/Swiss-Prot for ZNF263 Gene

  • Might play an important role in basic cellular processes as a transcriptional repressor

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF263 Gene

Genomics for ZNF263 Gene

Regulatory Elements for ZNF263 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF263 Gene

Start:
3,263,743 bp from pter
End:
3,301,401 bp from pter
Size:
37,659 bases
Orientation:
Plus strand

Genomic View for ZNF263 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF263 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF263 Gene

Proteins for ZNF263 Gene

  • Protein details for ZNF263 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O14978-ZN263_HUMAN
    Recommended name:
    Zinc finger protein 263
    Protein Accession:
    O14978
    Secondary Accessions:
    • B2R634
    • O43387
    • Q96H95

    Protein attributes for ZNF263 Gene

    Size:
    683 amino acids
    Molecular mass:
    77299 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF263 Gene

Proteomics data for ZNF263 Gene at MOPED

Post-translational modifications for ZNF263 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF263 Gene

No data available for DME Specific Peptides for ZNF263 Gene

Domains for ZNF263 Gene

Gene Families for ZNF263 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry

O14978

UniProtKB/Swiss-Prot:

ZN263_HUMAN :
  • O14978
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF263: view

Function for ZNF263 Gene

Molecular function for ZNF263 Gene

GENATLAS Biochemistry: zinc finger protein 263
UniProtKB/Swiss-Prot Function: Might play an important role in basic cellular processes as a transcriptional repressor

Gene Ontology (GO) - Molecular Function for ZNF263 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF263: view

Phenotypes for ZNF263 Gene

GenomeRNAi human phenotypes for ZNF263:
genes like me logo Genes that share phenotypes with ZNF263: view

Animal Model Products

CRISPR Products

miRNA for ZNF263 Gene

miRTarBase miRNAs that target ZNF263
Targeting motifs for ZNF263 Gene
HOMER Transcription Factor Regulatory Elements motif ZNF263
  • Consensus sequence: CNGTCCTCCC Submotif: canonical Cell Type: K562 GeoId: GSE31477

No data available for Enzyme Numbers (IUBMB) , Animal Models and Transcription Factor Targeting for ZNF263 Gene

Localization for ZNF263 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF263 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF263 Gene COMPARTMENTS Subcellular localization image for ZNF263 gene
Compartment Confidence
cytoskeleton 4
cytosol 4
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF263 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
GO:0015630 microtubule cytoskeleton IDA --
genes like me logo Genes that share ontologies with ZNF263: view

Pathways for ZNF263 Gene

SuperPathways for ZNF263 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF263: view

Pathways by source for ZNF263 Gene

2 Reactome pathways for ZNF263 Gene

Gene Ontology (GO) - Biological Process for ZNF263 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated TAS 9256059
GO:0045892 negative regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF263: view

Transcripts for ZNF263 Gene

Unigene Clusters for ZNF263 Gene

Zinc finger protein 263:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF263

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF263 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1:
SP2: - - - -
SP3: - -
SP4: - - - - -

Relevant External Links for ZNF263 Gene

GeneLoc Exon Structure for
ZNF263
ECgene alternative splicing isoforms for
ZNF263

Expression for ZNF263 Gene

mRNA expression in normal human tissues for ZNF263 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF263 Gene

SOURCE GeneReport for Unigene cluster for ZNF263 Gene Hs.611475

mRNA Expression by UniProt/SwissProt for ZNF263 Gene

O14978-ZN263_HUMAN
Tissue specificity: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte
genes like me logo Genes that share expressions with ZNF263: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF263 Gene

Orthologs for ZNF263 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF263 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF263 35
  • 99.61 (n)
  • 99.27 (a)
ZNF263 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF263 35
  • 89.51 (n)
  • 89.31 (a)
ZNF263 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF263 35
  • 90.53 (n)
  • 92.24 (a)
ZNF263 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp263 35
  • 84.74 (n)
  • 84.79 (a)
Zfp263 16
Zfp263 36
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF263 36
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 31 (a)
OneToMany
-- 36
  • 32 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp263 35
  • 83.33 (n)
  • 82.69 (a)
Species with no ortholog for ZNF263:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF263 Gene

ENSEMBL:
Gene Tree for ZNF263 (if available)
TreeFam:
Gene Tree for ZNF263 (if available)

Paralogs for ZNF263 Gene

Paralogs for ZNF263 Gene

Selected SIMAP similar genes for ZNF263 Gene using alignment to 9 proteins:

Pseudogenes.org Pseudogenes for ZNF263 Gene

genes like me logo Genes that share paralogs with ZNF263: view

Variants for ZNF263 Gene

Sequence variations from dbSNP and Humsavar for ZNF263 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs183388 -- 3,297,367(+) TGGAC(A/C)CCAGT intron-variant
rs183389 -- 3,297,376(+) GTAGT(A/T)CTGTA intron-variant
rs186371 -- 3,283,391(+) GTAGG(C/T)GGTGA upstream-variant-2KB, utr-variant-5-prime
rs188760 -- 3,286,561(+) TCGTC(C/T)CCAAA intron-variant
rs188761 -- 3,288,343(+) TGTCA(C/G)ATTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF263 Gene

Variant ID Type Subtype PubMed ID
dgv2583n71 CNV Loss 21882294

Relevant External Links for ZNF263 Gene

HapMap Linkage Disequilibrium report
ZNF263

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF263 Gene

Disorders for ZNF263 Gene

Relevant External Links for ZNF263

Human Genome Epidemiology (HuGE) Navigator
ZNF263
genes like me logo Genes that share disorders with ZNF263: view

No data available for UniProtKB/Swiss-Prot for ZNF263 Gene

Publications for ZNF263 Gene

  1. Isolation of a cDNA encoding a widely expressed novel zinc finger protein with the LeR and KRAB-A domains. (PMID: 9256059) Yokoyama M. … Fukushima A. (Biochim. Biophys. Acta 1997) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 3 4
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF263 Gene

Sources for ZNF263 Gene

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