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Aliases for ZNF26 Gene

Aliases for ZNF26 Gene

  • Zinc Finger Protein 26 2 3
  • Zinc Finger Protein KOX20 3 4
  • KOX20 3 4
  • Zinc Finger Protein 26 (KOX 20) 2
  • Epididymis Luminal Protein 179 3
  • HEL-179 3

External Ids for ZNF26 Gene

Summaries for ZNF26 Gene

GeneCards Summary for ZNF26 Gene

ZNF26 (Zinc Finger Protein 26) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF182.

UniProtKB/Swiss-Prot for ZNF26 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF26 Gene

Genomics for ZNF26 Gene

Genomic Location for ZNF26 Gene

Start:
132,986,348 bp from pter
End:
133,027,103 bp from pter
Size:
40,756 bases
Orientation:
Plus strand

Genomic View for ZNF26 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF26 Gene

Regulatory Elements for ZNF26 Gene

Transcription factor binding sites by QIAGEN in the ZNF26 gene promoter:

Proteins for ZNF26 Gene

  • Protein details for ZNF26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17031-ZNF26_HUMAN
    Recommended name:
    Zinc finger protein 26
    Protein Accession:
    P17031
    Secondary Accessions:
    • Q86X57
    • Q9NWL3

    Protein attributes for ZNF26 Gene

    Size:
    533 amino acids
    Molecular mass:
    61282 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH08211.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA91367.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF26 Gene

Proteomics data for ZNF26 Gene at MOPED

Post-translational modifications for ZNF26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF26 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF26 Gene

Domains for ZNF26 Gene

Gene Families for ZNF26 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF26 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17031

UniProtKB/Swiss-Prot:

ZNF26_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • P17031
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • P17031
Similarity:
  • Contains 13 C2H2-type zinc fingers.:
    • P17031
genes like me logo Genes that share domains with ZNF26: view

Function for ZNF26 Gene

Molecular function for ZNF26 Gene

GENATLAS Biochemistry: zinc finger protein 26 (KOX20) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF26: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF26 Gene

Localization for ZNF26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF26 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF26 Gene COMPARTMENTS Subcellular localization image for ZNF26 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF26: view

Pathways for ZNF26 Gene

SuperPathways for ZNF26 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF26: view

Pathways by source for ZNF26 Gene

2 Reactome pathways for ZNF26 Gene

Gene Ontology (GO) - Biological Process for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF26: view

Transcripts for ZNF26 Gene

Unigene Clusters for ZNF26 Gene

Zinc finger protein 26:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF26 Gene

No ASD Table

Relevant External Links for ZNF26 Gene

GeneLoc Exon Structure for
ZNF26
ECgene alternative splicing isoforms for
ZNF26

Expression for ZNF26 Gene

mRNA expression in normal human tissues for ZNF26 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF26 Gene

SOURCE GeneReport for Unigene cluster for ZNF26 Gene Hs.489608

genes like me logo Genes that share expressions with ZNF26: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF26 Gene

Orthologs for ZNF26 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF26 35
  • 99.65 (n)
  • 99.65 (a)
ZNF26 36
  • 100 (a)
OneToMany
cow
(Bos Taurus)
Mammalia ZNF26 35
  • 87.51 (n)
  • 88.5 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 29 (a)
ManyToMany
Species with no ortholog for ZNF26:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF26 Gene

ENSEMBL:
Gene Tree for ZNF26 (if available)
TreeFam:
Gene Tree for ZNF26 (if available)

Paralogs for ZNF26 Gene

Selected SIMAP similar genes for ZNF26 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF26: view

Variants for ZNF26 Gene

Sequence variations from dbSNP and Humsavar for ZNF26 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs4758930 -- 133,001,573(+) ACTGC(A/G)TGCAG intron-variant
rs7136219 -- 133,014,312(+) ggagg(C/T)tgagg downstream-variant-500B
rs7971178 -- 133,005,818(+) atgct(C/T)atgga intron-variant
rs9888354 -- 132,988,409(+) taaaa(A/T)ttttt intron-variant
rs10735673 -- 132,999,121(+) CTGTC(A/G)AATCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF26 Gene

Variant ID Type Subtype PubMed ID
dgv538e1 CNV Complex 17122850
dgv330e199 CNV Deletion 23128226
nsv899834 CNV Gain 21882294
nsv470336 CNV Gain 18288195
nsv455813 CNV Gain 19166990
dgv219n27 CNV Gain 19166990
nsv525745 CNV Gain 19592680
nsv438246 CNV Loss 16468122

Relevant External Links for ZNF26 Gene

HapMap Linkage Disequilibrium report
ZNF26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF26 Gene

Disorders for ZNF26 Gene

No disorders were found for ZNF26 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF26 Gene

Publications for ZNF26 Gene

  1. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Two human genes encoding zinc finger proteins, ZNF 12 (KOX 3) and ZNF 26 (KOX 20), map to chromosome 7p22-p21 and 12q24.33, respectively. (PMID: 2026422) Seite P. … Thiesen H.J. (Hum. Genet. 1991) 3

Products for ZNF26 Gene

Sources for ZNF26 Gene

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