Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF26 Gene

Aliases for ZNF26 Gene

  • Zinc Finger Protein 26 2 3 5
  • Zinc Finger Protein KOX20 3 4
  • KOX20 3 4
  • Zinc Finger Protein 26 (KOX 20) 2
  • Epididymis Luminal Protein 179 3
  • HEL-179 3

External Ids for ZNF26 Gene

Previous GeneCards Identifiers for ZNF26 Gene

  • GC12P131066
  • GC12P133116
  • GC12P131825
  • GC12P131393
  • GC12P132173
  • GC12P132073
  • GC12P133563
  • GC12P130343

Summaries for ZNF26 Gene

GeneCards Summary for ZNF26 Gene

ZNF26 (Zinc Finger Protein 26) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF605.

UniProtKB/Swiss-Prot for ZNF26 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF26 Gene

Genomics for ZNF26 Gene

Regulatory Elements for ZNF26 Gene

Enhancers for ZNF26 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F132487 1.6 FANTOM5 Ensembl ENCODE 42.2 -487.0 -486999 23.9 HDGF PKNOX1 ARNT CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZNF26 EP400NL ZNF891 FBRSL1 EP400 ZNF10 GOLGA3 NOC4L ENSG00000256875 ZNF84
GH12F132597 1 Ensembl ENCODE 32 -388.0 -388034 1.8 HDGF ARNT ZNF493 ZNF133 YBX1 GLI4 ZNF48 ZNF2 ZNF121 GLIS2 ZNF140 ZNF84 ENSG00000255933 EP400 ZNF26 ENSG00000250790 ZNF605 DDX51 GOLGA3 SFSWAP
GH12F132827 0.5 ENCODE 24.6 -157.9 -157866 2.6 PKNOX1 ARNT CREB3L1 MLX WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ANKLE2 ZNF26 ZNF891 ZNF140 EP400 ZNF10 ENSG00000255919 PUS1 ZNF84 NOC4L
GH12F132600 0.8 FANTOM5 Ensembl ENCODE 12.8 -383.9 -383909 4.8 MLX CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 CBX5 ZNF143 POLE ZNF140 GOLGA3 EP400 ZNF10 P2RX2 ZNF26 PXMP2 ENSG00000256632 DDX51
GH12F132954 1 ENCODE 10.7 -30.6 -30612 2.4 ATF1 ARID4B SIN3A DMAP1 ZNF2 YY1 ETS1 GLIS2 CBX5 ZNF143 ZNF84 ZNF891 ENSG00000250790 ZNF140 DDX51 LOC101928597 ENSG00000256825 ZNF10 ZNF268 ZNF26
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF26 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF26 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000092095 453 2399 HDGF CREB3L1 MLX ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF143

Transcription factor binding sites by QIAGEN in the ZNF26 gene promoter:

Genomic Location for ZNF26 Gene

Chromosome:
12
Start:
132,986,348 bp from pter
End:
133,032,952 bp from pter
Size:
46,605 bases
Orientation:
Plus strand

Genomic View for ZNF26 Gene

Genes around ZNF26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF26 Gene

Proteins for ZNF26 Gene

  • Protein details for ZNF26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17031-ZNF26_HUMAN
    Recommended name:
    Zinc finger protein 26
    Protein Accession:
    P17031
    Secondary Accessions:
    • Q86X57
    • Q9NWL3

    Protein attributes for ZNF26 Gene

    Size:
    533 amino acids
    Molecular mass:
    61282 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH08211.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA91367.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF26 Gene

Post-translational modifications for ZNF26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF26 Gene

Domains & Families for ZNF26 Gene

Gene Families for ZNF26 Gene

Protein Domains for ZNF26 Gene

Suggested Antigen Peptide Sequences for ZNF26 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17031

UniProtKB/Swiss-Prot:

ZNF26_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF26: view

Function for ZNF26 Gene

Molecular function for ZNF26 Gene

GENATLAS Biochemistry:
zinc finger protein 26 (KOX20) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF26: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF26 Gene

Localization for ZNF26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF26 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF26 Gene COMPARTMENTS Subcellular localization image for ZNF26 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF26: view

Pathways & Interactions for ZNF26 Gene

SuperPathways for ZNF26 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF26: view

Pathways by source for ZNF26 Gene

2 Reactome pathways for ZNF26 Gene

Gene Ontology (GO) - Biological Process for ZNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF26: view

No data available for SIGNOR curated interactions for ZNF26 Gene

Transcripts for ZNF26 Gene

Unigene Clusters for ZNF26 Gene

Zinc finger protein 26:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF26 Gene

No ASD Table

Relevant External Links for ZNF26 Gene

GeneLoc Exon Structure for
ZNF26
ECgene alternative splicing isoforms for
ZNF26

Expression for ZNF26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF26 Gene

Protein differential expression in normal tissues from HIPED for ZNF26 Gene

This gene is overexpressed in Skin (59.3) and Heart (9.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF26 Gene



Protein tissue co-expression partners for ZNF26 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF26 Gene:

ZNF26

SOURCE GeneReport for Unigene cluster for ZNF26 Gene:

Hs.489608
genes like me logo Genes that share expression patterns with ZNF26: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF26 Gene

Orthologs for ZNF26 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF26 34 35
  • 99.65 (n)
cow
(Bos Taurus)
Mammalia ZNF26 34
  • 87.51 (n)
dog
(Canis familiaris)
Mammalia -- 35
  • 29 (a)
ManyToMany
Species where no ortholog for ZNF26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF26 Gene

ENSEMBL:
Gene Tree for ZNF26 (if available)
TreeFam:
Gene Tree for ZNF26 (if available)

Paralogs for ZNF26 Gene

(541) SIMAP similar genes for ZNF26 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF26: view

Variants for ZNF26 Gene

Sequence variations from dbSNP and Humsavar for ZNF26 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10632849 -- 133,022,477(+) TACAC(-/ACAT/ATAT)ACATA intron-variant
rs10667689 -- 133,022,484(+) ATACA(-/TACA)AAGTA intron-variant
rs10735673 -- 132,999,121(+) CTGTC(A/G)AATCC intron-variant
rs10747092 -- 132,984,991(+) CAAGA(A/G)TGTAC upstream-variant-2KB
rs10747093 -- 133,004,675(+) AGATG(A/G)GGTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF26 Gene

Variant ID Type Subtype PubMed ID
dgv1590n100 CNV gain 25217958
dgv1591n100 CNV gain 25217958
dgv219n27 CNV gain 19166990
dgv3059n54 CNV gain 21841781
dgv330e199 CNV deletion 23128226
dgv917n106 CNV deletion 24896259
esv2759923 CNV loss 17122850
esv2763013 CNV gain 21179565
nsv1054709 CNV loss 25217958
nsv1054933 CNV gain 25217958
nsv1071081 CNV deletion 25765185
nsv438246 CNV loss 16468122
nsv455813 CNV gain 19166990
nsv470336 CNV gain 18288195
nsv525745 CNV gain 19592680
nsv561142 CNV gain 21841781

Relevant External Links for ZNF26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF26

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ZNF26 Gene

Disorders for ZNF26 Gene

Relevant External Links for ZNF26

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF26

No disorders were found for ZNF26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF26 Gene

Publications for ZNF26 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4 64
  4. Microtubule-associated proteins 1 (MAP1) promote human immunodeficiency virus type I (HIV-1) intracytoplasmic routing to the nucleus. (PMID: 25505242) Fernandez J. … Arhel N.J. (J. Biol. Chem. 2015) 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for ZNF26 Gene

Sources for ZNF26 Gene

Content
Loading form....