ZNF26 Gene
protein-coding GIFtS: 46
GCID: GC12P133563
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zinc finger protein 26(Previous name: zinc finger protein 26 (KOX 20) )
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Aliases
for ZNF26 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 261 2 | | KOX201 2 3 | | Zinc Finger Protein KOX202 3 | | FLJ207551 | | Zinc Finger Protein 26 (KOX 20)1 |
Export aliases for ZNF26 gene to outside databasesPrevious GC identifers: GC12P131066 GC12P133116 GC12P131825 GC12P131393 GC12P132173 GC12P132073 GC12P130343 |
Summaries
for ZNF26 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZNF26_HUMAN, P17031Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF26 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_024477.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF26 gene promoter:
AhR Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF26
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF26 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.33 Ensembl cytogenetic band: 12q24.33 HGNC cytogenetic band: 12q24.33ZNF26 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P133563: view genomic region
(about GC identifiers)
Start:
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133,562,951 bp from pter |
End:
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133,589,154 bp from pter |
Size:
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26,204 bases |
Orientation:
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plus strand |
0 alternative location:
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Proteins
for ZNF26 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZNF26_HUMAN, P17031 (See
protein sequence)Recommended Name: Zinc finger protein 26 Size: 533 amino acids; 61282 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=AAH08211.1; Type=Erroneous initiation; Sequence=BAA91367.1; Type=Erroneous initiation;
Secondary accessions: Q86X57 Q9NWL3Explore the universe of human proteins at neXtProt for ZNF26: NX_P17031
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P17031
ZNF26 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001243208.1 NP_001243209.1 NP_062537.2
ENSEMBL proteins: ENSP00000443888 ENSP00000333725 ENSP00000445494 ENSP00000437420 Reactome Protein details: P17031
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF26 for ontologies About GeneDecksing
ZNF26 Antibody Products:
Assay Products for ZNF26: |
Protein
Domains /
Families
for ZNF26 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF26 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P17031ProtoNet protein and cluster: P17031 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZNF26_HUMAN, P17031Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 13 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF26 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZNF26_HUMAN, P17031Function: May be involved in transcriptional regulation Genatlas biochemistry entry for ZNF26:zinc finger protein 26 (KOX20) (C2H2 type,Kruppel-like)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF26
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF26 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: ZNF26 (NM_019591) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF26 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF26 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF26 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF26 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF26 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF26
ZNF26 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF26
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF26 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF26 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF26
Search CenterWatch for drugs/clinical trials and news about ZNF26
|
Transcripts
for ZNF26 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF26 gene (3 alternative transcripts): NM_001256279.1 NM_001256280.1 NM_019591.3 Unigene Cluster for ZNF26: Zinc finger protein 26 Hs.489608 [show with all ESTs]Unigene Representative Sequence: AK1229416 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000537956 ENST00000545101 ENST00000540238 ENST00000328654(uc001ull.1)
ENST00000544181 ENST00000534834
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF26
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF26 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF26 (NM_019591) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF26 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF26 |
Additional cDNA sequence: AK000762.1 AK122941.1 AK225296.1 AK291243.1 AL833057.1 BC008211.1 BC046206.2 BT006963.1 X52351.1 9 DOTS entries: DT.121213915 DT.99962016 DT.452910 DT.441787 DT.102824653 DT.99944664 DT.121213909 DT.121214192 DT.40283062 24/50 AceView cDNA sequences (see all 50): AI002259 R55614 NM_019591 BC008211 AI791872 AL833057 BX089966 AK122941 AW339163 AI636163 AW168597 AA310358 AK000762 BQ710688 BU194644 R97944 R55615 BE218108 BQ027811 AA906510 BI914253 BG400511 CB069076 AA604739
GeneLoc Exon Structure
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Expression
for ZNF26 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF26 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACCAGAAAA
About this image
See ZNF26 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF26
SOURCE GeneReport for Unigene cluster: Hs.489608
SABiosciences Custom PCR Arrays for ZNF26
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF26
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF26 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF26 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF26 |
Orthologs
for ZNF26 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF26 gene from 1/5 species (see all 5) About this table
ENSEMBL Gene Tree for ZNF26 (if available)
TreeFam Gene Tree for ZNF26 (if available) |
Paralogs
for ZNF26 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF26 gene
- ZNF1752 ZNF6742 LOC1002875152 ZNF6142 ZNF4322 ZNF6132 ZNF3502 ZNF812
- ZNF6492 ZNF6052 ZNF5772 ZNF842 ZNF6302 ZFP372 ZNF4842 ENSG000002296312
- ZNF1822 ZNF412 ZNF2682 LOC1009964642 ZNF6152 ZNF3002
18/534 SIMAP similar genes for ZNF26 using alignment to 4 protein entries: ZNF26_HUMAN (see all proteins)
(see all similar genes):DKFZp666M039 ZFS-4 ZNF818P DKFZp313M0722 ZNF323 ZNF717
ZNF229 ZNF282 ZNF55 ZNF66 ZNF624 ZNF506
ZNF420 ZNF573 ZNF569 HZF36 KRBOX4 ZNF271
ZNF26 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF26 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF26 (133562951 - 133589154 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ZNF26
3 CNVs: 1941 3903 53373 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF26 |
|
Disorders
/ Diseases
for ZNF26 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF26 for disorders About MalaCards
ZNF26 for disorders About GeneDecksing
OMIM gene information: 194537
OMIM disorders: --
Export disorders for ZNF26 gene to outside databases
|
Publications
for ZNF26 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF26 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF26) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (1990)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)
- Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
- Two human genes encoding zinc finger proteins, ZNF 12 (KOX 3) and ZNF 26 (KOX 20), map to chromosome 7p22-p21 and 12q24.33, respectively. (PubMed id 2026422)1 Seite P....Thiesen H.J. (1991)
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External Searches for ZNF26 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF26 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF26 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF26 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF26 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for ZNF26 gene:
Search GeneIP for patents involving ZNF26
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF26 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF26 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF26 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF26 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF26 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF26 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF26 |
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 | | | ZNF26 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF26 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF26 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF26 |
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