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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF259 Gene

protein-coding   GIFtS: 61
GCID: GC11M116648

Zinc Finger Protein 259

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 2591 2 3
ZPR12 3
Zinc Finger Protein ZPR12

External Ids:    HGNC: 130511   Entrez Gene: 88822   Ensembl: ENSG000001099177   OMIM: 6039015   UniProtKB: O753123   

Export aliases for ZNF259 gene to outside databases

Previous GC identifers: GC11M119002 GC11M118161 GC11M116682 GC11M116186 GC11M116154 GC11M112581


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZNF259 Gene: 
ZNF259 (zinc finger protein 259) is a protein-coding gene. Diseases associated with ZNF259 include gigantism, and spinal muscular atrophy. GO annotations related to this gene include zinc ion binding.

UniProtKB/Swiss-Prot: ZPR1_HUMAN, O75312
Function: May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus

Gene Wiki entry for ZNF259 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_033899.8  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF259 gene promoter:
         PPAR-alpha   PPAR-gamma1   HNF-4alpha2   PPAR-gamma2   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF259 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF259

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF259


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q23.3

ZNF259 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF259 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M116648:  view genomic region     (about GC identifiers)

Start:
116,648,436 bp from pter      End:
116,658,766 bp from pter
Size:
10,331 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZPR1_HUMAN, O75312 (See protein sequence)
Recommended Name: Zinc finger protein ZPR1  
Size: 459 amino acids; 50925 Da
Subunit: Binds to the EGF and PDGF receptors. Binds to the elongation factor 1-alpha EF1A (By similarity).
Component of an import snRNP complex composed of KPNB1, SNUPN, SMN1 and ZNF259
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Translocates to the nucleolus after treatment with
mitogens
Secondary accessions: Q2TAA0

Explore the universe of human proteins at neXtProt for ZNF259: NX_O75312

Explore proteomics data for ZNF259 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75312

  • ZNF259 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZNF259 Protein Expression
    REFSEQ proteins: NP_003895.1  
    ENSEMBL proteins: 
     ENSP00000394495   ENSP00000390391   ENSP00000227322   ENSP00000415505   ENSP00000391077  
     ENSP00000410141  

    Human Recombinant Protein Products for ZNF259: 
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    Novus Biologicals ZNF259 Proteins
    Novus Biologicals ZNF259 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF259 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS8650580
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IEA--

    ZNF259 for ontologies           About GeneDecksing



    ZNF259 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for ZNF259 
    Cloud-Clone Corp. CLIAs for ZNF259


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    1 InterPro protein domain:
     IPR004457 Znf_ZPR1

    Graphical View of Domain Structure for InterPro Entry O75312

    ProtoNet protein and cluster: O75312

    1 Blocks protein domain: IPB004457 Zn-finger

    UniProtKB/Swiss-Prot: ZPR1_HUMAN, O75312
    Similarity: Belongs to the ZPR1 family


    ZNF259 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZPR1_HUMAN, O75312
    Function: May be a signaling molecule that communicates mitogenic signals from the cytoplasm to the nucleus

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    ZNF259 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF259:
     Synthetic lethal with Ras 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Zfp259):
     cellular  embryogenesis  mortality/aging 

    ZNF259 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Zfp259tm1Rjd for ZNF259

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZNF259 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZNF259

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF259 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF259 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidZNF259 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Clone
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    GenScript: all cDNA clones in your preferred vector: ZNF259 (NM_003904)
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF259


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ZNF259 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1EGFR1 Signaling Pathway
    EGFR1 Signaling Pathway
    2Translational Control
    Translational Control

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ZNF259
        Translational Control

    1 BioSystems Pathway for ZNF259
        EGFR1 Signaling Pathway



    ZNF259 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZNF259

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/36 Interacting proteins for ZNF259 (O753122, 3 ENSP000002273224) via UniProtKB, MINT, STRING, and/or I2D (see all 36)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CDK5RAP2Q96SN82, 3MINT-65250 I2D: score=5 
    SMARCB1Q128243, ENSP000002631214I2D: score=4 STRING: ENSP00000263121
    EEF1A1P681043, ENSP000003300544I2D: score=11 STRING: ENSP00000330054
    RBX1P628773, ENSP000002162254I2D: score=10 STRING: ENSP00000216225
    SNUPNO951493, ENSP000003098314I2D: score=1 STRING: ENSP00000309831
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS8650580
    GO:0008283cell proliferation TAS9763455

    ZNF259 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ZNF259 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF259 (ZPR1)

    1 Novoseek inferred chemical compound relationship for ZNF259 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 55.5 8 9763455 (2), 17068332 (2), 19966453 (2), 8650580 (1) (see all 5)

    Search CenterWatch for drugs/clinical trials and news about ZNF259 / ZPR1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF259 gene: 
    NM_003904.3  

    Unigene Cluster for ZNF259:

    Zinc finger protein 259
    Hs.7165  [show with all ESTs]
    Unigene Representative Sequence: BC111028
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000429220 ENST00000444935 ENST00000227322(uc001ppp.3) ENST00000449430
    ENST00000431973 ENST00000425791 ENST00000498065 ENST00000487030

    miRNA
    Products:
         
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZNF259
    SwitchGear 3'UTR luciferase reporter plasmidZNF259 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZNF259
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF259
    Clone
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    OriGene clones in human, mouse for ZNF259 (see all 8)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF259 (NM_003904)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF259
    Sirion Biotech Customized lentivirus for stable overexpression of ZNF259 
                         Customized lentivirus expression plasmids for stable overexpression of ZNF259 
    Primer
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    OriGene qPCR primer pairs and template standards for ZNF259
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF259
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF259

    Additional mRNA sequence: 

    AF019767.1 AK301227.1 BC004256.1 BC011929.2 BC012162.1 BC017349.2 BC017380.2 BC111028.1 
    BT006642.1 

    11 DOTS entries:

    DT.411006  DT.100757686  DT.95340942  DT.100818718  DT.120746555  DT.120746536  DT.75172205  DT.86852865 
    DT.95340939  DT.121328635  DT.97847038 

    24/288 AceView cDNA sequences (see all 288):

    BM910418 CR594434 BF056026 BU623976 BQ069170 CB148717 BM450633 AW006230 
    CR622469 BM724560 BU728594 BG575759 BC017380 BQ671401 AI198352 BQ641496 
    BM695880 BF514945 NM_052968 BC012162 BQ928228 CR626297 BU189482 BM982523 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF259    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:                                                                                                
    SP2:        -                                                                                       
    SP3:                                                                                                


    ECgene alternative splicing isoforms for ZNF259

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF259 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGGGGAGGA
    ZNF259 Expression
    About this image


    See ZNF259 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF259

    SOURCE GeneReport for Unigene cluster: Hs.7165
        SABiosciences Custom PCR Arrays for ZNF259
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF259

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ZNF259 gene from 10/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp2591 , 5 zinc finger protein 2591, 5 87.15(n)1
    90.41(a)1
      9 (25.38 cM)5
    226871  NM_011752.21  NP_035882.11 
     462730645 
    chicken
    (Gallus gallus)
    Aves ZNF2591 zinc finger protein 259 74.2(n)
    77.17(a)
      428256  XM_003642595.1  XP_003642643.1 
    lizard
    (Anolis carolinensis)
    Reptilia ZNF2596
    Uncharacterized protein
    70(a)
    1 ↔ 1
    GL343949.1(74516-83300)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.66332 Xenopus laevis transcribed sequence with weak similarity more 78.46(n)    48047047 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc17g092 Danio rerio mRNA similar to zinc finger protein 259 more 76.62(n)    BC052111.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Zpr11 , 3 transcription from Pol I promoter3
    CG9060-PA1
    48(a)3
    56.36(n)1
    50.7(a)1
      8D83
    318511  NM_132304.21  NP_572532.11 
    worm
    (Caenorhabditis elegans)
    Secernentea W03F9.13
    CELE_W03F9.11
    Protein W03F9.11 40(a)3
    50.51(n)1
    41.81(a)1
      V(124206-126477)3
    1891621  NM_070737.21  NP_503138.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ZPR1(YGR211W)4
    ZPR11
    Essential protein with two zinc fingers, present in more4
    Zpr1p1
    53.79(n)1
    50.61(a)1
      7(915241-916701)4
    8531251, 4  NP_011727.31  NP_011727.14 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G224801 ZPR1 zinc-finger domain protein 53.48(n)
    45.21(a)
      832309  NM_122153.4  NP_197640.1 
    rice
    (Oryza sativa)
    Liliopsida Os.271082 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 69.61(n)    AK069434.1 


    ENSEMBL Gene Tree for ZNF259 (if available)
    TreeFam Gene Tree for ZNF259 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF259 gene

    ZNF259 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ZNF259
    PGOHUM00000243320


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/277 SNPs in ZNF259 are shown (see all 277)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs782965221,2
    C,F--116648776(+) TCCTCC/ATCAGC 1 -- int12Minor allele frequency- A:0.07NA EA 240
    rs1387330821,2
    C--116648802(+) AATTAC/TCACCT 1 -- int10--------
    rs1427319941,2
    --116648851(+) CACAAC/TCCAGC 1 -- int10--------
    rs6411691,2
    C,F,H--116648900(+) ccatcT/Cgatgt 1 -- int1 ese34Minor allele frequency- C:0.01NS EA 410
    rs1394294541,2
    --116648911(+) ACTGTC/TTTCCT 1 -- int10--------
    rs9641841,2
    C,F,O,H--116648917(+) TTCCTC/GATCTG 1 -- int1 ese331Minor allele frequency- G:0.24NS EA MN NA WA CSA 2742
    rs1117325541,2
    C,F--116649131(+) ACAAGG/CATAGG 1 -- int12Minor allele frequency- C:0.03NA 122
    rs118235431,2
    C,F,H--116649135(+) GGATAG/AGGTCA 1 -- int1 ese317Minor allele frequency- A:0.12NS EA NA WA CSA 1892
    rs1826905841,2
    --116649367(+) TGATAA/TGAAAA 1 -- ut310--------
    rs1868757491,2
    --116649436(+) CCAAAA/GTAAGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZNF259 (116648436 - 116658766 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ZNF259:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv507CNV Loss18451855

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF259
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF259

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603901    OMIM disorders: --

    7 diseases for ZNF259:    About MalaCards
    gigantism    spinal muscular atrophy    muscular atrophy    hypertriglyceridemia
    coronary heart disease    atherosclerosis    neuronitis

    2 diseases from the University of Copenhagen DISEASES database for ZNF259:
    Werdnig-Hoffmann disease     Muscular atrophy

    ZNF259 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): ZNF259
    Human Genome Epidemiology (HuGE) Navigator: ZNF259 (7 documents)

    Export disorders for ZNF259 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF259 gene, integrated from 9 sources (see all 47):
    (articles sorted by number of sources associating them with ZNF259)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells. (PubMed id 9763455)1, 2, 3, 9 Galcheva-Gargova Z.... Davis R.J. (1998)
    2. Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor. (PubMed id 8650580)1, 3, 9 Galcheva-Gargova Z....Davis R.J. (1996)
    3. Genome-wide screen for metabolic syndrome susceptibili ty Loci reveals strong lipid gene contribution but no evidence for common geneti c basis for clustering of metabolic syndrome traits. (PubMed id 22399527)1, 4 Kristiansson K....Salomaa V. (2012)
    4. Eight genetic loci associated with variation in lipopr otein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studi es. (PubMed id 22003152)1, 4 Grallert H....Ballantyne C.M. (2012)
    5. Genome-wide association study identifies novel loci as sociated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1, 4 Demirkan A....Schmitz G. (2012)
    6. Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men. (PubMed id 22437554)1, 4 Major J.M....Albanes D. (2012)
    7. A bivariate genome-wide approach to metabolic syndrom e: STAMPEED consortium. (PubMed id 21386085)1, 4 Kraja A.T....Borecki I.B. (2011)
    8. Genome-wide association study identifies common varian ts associated with circulating vitamin E levels. (PubMed id 21729881)1, 4 Major J.M....Albanes D. (2011)
    9. Large-scale genome-wide association studies in East As ians identify new genetic loci influencing metabolic traits. (PubMed id 21909109)1, 4 Kim Y.J....Cho Y.S. (2011)
    10. Large-scale association analysis identifies 13 new su sceptibility loci for coronary artery disease. (PubMed id 21378990)1, 4 Schunkert H....Samani N.J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8882 HGNC: 13051 AceView: ZNF259andAPOA5 Ensembl:ENSG00000109917 euGenes: HUgn8882
    ECgene: ZNF259 H-InvDB: ZNF259

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF259 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF259 gene:
    Search GeneIP for patents involving ZNF259

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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