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Aliases for ZNF251 Gene

Aliases for ZNF251 Gene

  • Zinc Finger Protein 251 2 3

External Ids for ZNF251 Gene

Previous GeneCards Identifiers for ZNF251 Gene

  • GC00U990512
  • GC08M145951
  • GC08M145561
  • GC08M145917
  • GC08M141061
  • GC08M145946

Summaries for ZNF251 Gene

GeneCards Summary for ZNF251 Gene

ZNF251 (Zinc Finger Protein 251) is a Protein Coding gene. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF251 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF251 Gene

Genomics for ZNF251 Gene

Regulatory Elements for ZNF251 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF251 Gene

144,720,907 bp from pter
144,760,817 bp from pter
39,911 bases
Minus strand

Genomic View for ZNF251 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF251 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF251 Gene

Proteins for ZNF251 Gene

  • Protein details for ZNF251 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 251
    Protein Accession:
    Secondary Accessions:
    • Q2M219

    Protein attributes for ZNF251 Gene

    671 amino acids
    Molecular mass:
    75763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF251 Gene

Proteomics data for ZNF251 Gene at MOPED

Post-translational modifications for ZNF251 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF251 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF251 Gene

Domains for ZNF251 Gene

Gene Families for ZNF251 Gene

Protein Domains for ZNF251 Gene

Suggested Antigen Peptide Sequences for ZNF251 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF251: view

Function for ZNF251 Gene

Molecular function for ZNF251 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF251 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF251: view

Animal Model Products

CRISPR Products

miRNA for ZNF251 Gene

miRTarBase miRNAs that target ZNF251

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF251 Gene

Localization for ZNF251 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF251 Gene

Subcellular locations from

Jensen Localization Image for ZNF251 Gene COMPARTMENTS Subcellular localization image for ZNF251 gene
Compartment Confidence
nucleus 4
cytosol 1

Gene Ontology (GO) - Cellular Components for ZNF251 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF251: view

Pathways for ZNF251 Gene

SuperPathways for ZNF251 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF251 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF251: view

No data available for Pathways by source for ZNF251 Gene

Transcripts for ZNF251 Gene

Unigene Clusters for ZNF251 Gene

Zinc finger protein 251:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF251

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF251 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7
SP1: - - - -
SP2: - -
SP4: -

Relevant External Links for ZNF251 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF251 Gene

mRNA expression in normal human tissues for ZNF251 Gene

Protein differential expression in normal tissues for ZNF251 Gene

This gene is overexpressed in Urine (35.6) and Adrenal (30.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF251 Gene

SOURCE GeneReport for Unigene cluster for ZNF251 Gene Hs.534516

genes like me logo Genes that share expressions with ZNF251: view

Expression partners for ZNF251 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF251 Gene

Orthologs for ZNF251 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF251 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Zfp251 35
  • 76.85 (n)
  • 74.37 (a)
Zfp251 16
Zfp251 36
  • 74 (a)
(Pan troglodytes)
Mammalia ZNF251 35
  • 99.21 (n)
  • 98.81 (a)
ZNF251 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zfp251 35
  • 77.71 (n)
  • 75.24 (a)
(Bos Taurus)
Mammalia -- 36
  • 47 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 31 (a)
Species with no ortholog for ZNF251:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF251 Gene

Gene Tree for ZNF251 (if available)
Gene Tree for ZNF251 (if available)

Paralogs for ZNF251 Gene

(512) SIMAP similar genes for ZNF251 Gene using alignment to 3 proteins: Pseudogenes for ZNF251 Gene

genes like me logo Genes that share paralogs with ZNF251: view

Variants for ZNF251 Gene

Sequence variations from dbSNP and Humsavar for ZNF251 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs11676 -- 144,721,060(-) TACAG(G/T)TTAAC utr-variant-3-prime
rs2258589 -- 144,721,402(-) ATCCG(C/G)ATACT utr-variant-3-prime
rs2466400 -- 144,723,970(+) CAGGC(A/G)CGGTG intron-variant
rs2466953 -- 144,750,918(+) aatct(C/T)ggctc intron-variant
rs2466954 -- 144,725,291(+) attac(A/G)ggcgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF251 Gene

Variant ID Type Subtype PubMed ID
nsv891807 CNV Loss 21882294
nsv428208 CNV Gain 18775914
nsv891897 CNV Loss 21882294
nsv522459 CNV Loss 19592680
nsv891925 CNV Loss 21882294
nsv891926 CNV Gain 21882294
dgv7985n71 CNV Loss 21882294

Relevant External Links for ZNF251 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF251 Gene

Disorders for ZNF251 Gene

Relevant External Links for ZNF251

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for ZNF251 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZNF251 Gene

Publications for ZNF251 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PMID: 22990118) Woods N.T. … Monteiro A.N. (Sci Signal 2012) 3
  5. DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 4

Products for ZNF251 Gene

Sources for ZNF251 Gene

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