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Aliases for ZNF25 Gene

Aliases for ZNF25 Gene

  • Zinc Finger Protein 25 2 3
  • KOX19 3 4 6
  • Zinc Finger Protein 25 (KOX 19) 2 3
  • Zinc Finger Protein KOX19 3 4
  • Zfp9 3

External Ids for ZNF25 Gene

Summaries for ZNF25 Gene

GeneCards Summary for ZNF25 Gene

ZNF25 (Zinc Finger Protein 25) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF182.

UniProtKB/Swiss-Prot for ZNF25 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF25 Gene

Genomics for ZNF25 Gene

Genomic Location for ZNF25 Gene

37,949,572 bp from pter
37,976,656 bp from pter
27,085 bases
Minus strand

Genomic View for ZNF25 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF25 Gene

Regulatory Elements for ZNF25 Gene

Proteins for ZNF25 Gene

  • Protein details for ZNF25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 25
    Protein Accession:
    Secondary Accessions:
    • A9Z1X5
    • Q8IYE3
    • Q8NDD6
    • Q96MU2

    Protein attributes for ZNF25 Gene

    456 amino acids
    Molecular mass:
    53545 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH36038.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF25 Gene


neXtProt entry for ZNF25 Gene

Proteomics data for ZNF25 Gene at MOPED

Post-translational modifications for ZNF25 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF25 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF25 Gene

Domains for ZNF25 Gene

Gene Families for ZNF25 Gene

  • ZNF :Zinc fingers, C2H2-type


  • Contains 1 KRAB domain.:
    • P17030
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • P17030
  • Contains 12 C2H2-type zinc fingers.:
    • P17030
genes like me logo Genes that share domains with ZNF25: view

Function for ZNF25 Gene

Molecular function for ZNF25 Gene

GENATLAS Biochemistry: zinc finger protein 25 (KOX19) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF25: view

miRNA for ZNF25 Gene

miRTarBase miRNAs that target ZNF25

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF25 Gene

Localization for ZNF25 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF25 Gene

Subcellular locations from

Jensen Localization Image for ZNF25 Gene COMPARTMENTS Subcellular localization image for ZNF25 gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ZNF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF25: view

Pathways for ZNF25 Gene

SuperPathways for ZNF25 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF25: view

Pathways by source for ZNF25 Gene

2 Reactome pathways for ZNF25 Gene

Gene Ontology (GO) - Biological Process for ZNF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF25: view

Transcripts for ZNF25 Gene

Unigene Clusters for ZNF25 Gene

Zinc finger protein 25:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF25 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b
SP1: - - - - -
SP2: - - - - - -
SP3: - - - -
SP4: - - -
SP6: - - -

Relevant External Links for ZNF25 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF25 Gene

mRNA expression in normal human tissues for ZNF25 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF25 Gene Hs.499429

genes like me logo Genes that share expressions with ZNF25: view

Orthologs for ZNF25 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF25 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF25 36
  • 99.27 (n)
  • 98.9 (a)
ZNF25 37
  • 99 (a)
(Bos Taurus)
Mammalia ZNF25 36
  • 87.93 (n)
  • 84 (a)
ZNF25 37
  • 83 (a)
(Canis familiaris)
Mammalia ZNF25 36
  • 87.48 (n)
  • 85.78 (a)
ZNF25 37
  • 73 (a)
(Mus musculus)
Mammalia Zfp9 36
  • 81.64 (n)
  • 78.85 (a)
Zfp9 16
Zfp9 37
  • 79 (a)
(Monodelphis domestica)
Mammalia -- 37
  • 41 (a)
-- 37
  • 45 (a)
-- 37
  • 44 (a)
-- 37
  • 42 (a)
-- 37
  • 45 (a)
-- 37
  • 42 (a)
-- 37
  • 35 (a)
-- 37
  • 36 (a)
-- 37
  • 42 (a)
-- 37
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 35 (a)
(Rattus norvegicus)
Mammalia Zfp9 36
  • 82.56 (n)
  • 78.46 (a)
Species with no ortholog for ZNF25:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF25 Gene

Gene Tree for ZNF25 (if available)
Gene Tree for ZNF25 (if available)

Paralogs for ZNF25 Gene

Selected SIMAP similar genes for ZNF25 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF25: view

Variants for ZNF25 Gene

Sequence variations from dbSNP and Humsavar for ZNF25 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs13503 -- 37,950,915(+) CCCTG(A/C)TCACA utr-variant-3-prime
rs766362 -- 37,961,278(+) TTAAA(C/G)CAACA intron-variant
rs1022448 -- 37,971,516(+) CTGCA(A/G)ACCAC intron-variant
rs1208601 -- 37,949,406(+) ATTAG(A/C)CAGGT downstream-variant-500B
rs1208602 -- 37,949,808(+) TGGCC(A/G)TTGAT downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF25 Gene

Variant ID Type Subtype PubMed ID
nsv895030 CNV Loss 21882294

Relevant External Links for ZNF25 Gene

HapMap Linkage Disequilibrium report

Disorders for ZNF25 Gene

(1) University of Copenhagen DISEASES for ZNF25 Gene

Relevant External Links for ZNF25

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with ZNF25: view

No data available for UniProtKB/Swiss-Prot for ZNF25 Gene

Publications for ZNF25 Gene

  1. Duplicated KOX zinc finger gene clusters flank the centromere of human chromosome 10: evidence for a pericentric inversion during primate evolution. (PMID: 8464732) Tunnacliffe A. … Ponder B.A. (Nucleic Acids Res. 1993) 2 3 23
  2. A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10. (PMID: 1639412) Rousseau-Merck M.F. … Thiesen H.J. (Genomics 1992) 2 3
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for ZNF25 Gene

Sources for ZNF25 Gene

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