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ZNF248 Gene

protein-coding   GIFtS: 52
GCID: GC10M038091

Zinc Finger Protein 248

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 2481 2
bA162G10.32
BA162G10.3 (Zinc Finger Protein)2
KRAB Protein Domain2
Kruppel-Type Zinc Finger Protein2

External Ids:    HGNC: 130411   Entrez Gene: 572092   Ensembl: ENSG000001981057   UniProtKB: Q8NDW43   

Export aliases for ZNF248 gene to outside databases

Previous GC identifers: GC00U990515 GC10M038121 GC10M038157 GC10M038131 GC10M037825


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF248 Gene:
ZNF248 (zinc finger protein 248) is a protein-coding gene. An important paralog of this gene is ZNF175.

UniProtKB/Swiss-Prot: ZN248_HUMAN, Q8NDW4
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_008705.17  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF248 gene promoter:
         GR   GR-beta   c-Myb   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF248 promoter sequence
   Search Chromatin IP Primers for ZNF248

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF248


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p11.2   Ensembl cytogenetic band:  10p11.1   HGNC cytogenetic band: 10p11.21

ZNF248 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF248 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M038091:  view genomic region     (about GC identifiers)

Start:
38,091,751 bp from pter      End:
38,147,034 bp from pter
Size:
55,284 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZN248_HUMAN, Q8NDW4 (See protein sequence)
Recommended Name: Zinc finger protein 248  
Size: 579 amino acids; 67087 Da
Secondary accessions: Q8NDV8 Q9UMP3
Alternative splicing: 2 isoforms:  Q8NDW4-1   Q8NDW4-2   

Explore the universe of human proteins at neXtProt for ZNF248: NX_Q8NDW4

Explore proteomics data for ZNF248 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF248 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001254526.1  NP_001254534.1  NP_001254535.1  NP_001254536.1  NP_066383.1  

    ENSEMBL proteins: 
     ENSP00000473904   ENSP00000379208   ENSP00000363778   ENSP00000379214   ENSP00000379215  
     ENSP00000349882  
    Reactome Protein details: Q8NDW4

    ZNF248 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZNF248

     
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    antibodies-online proteins for ZNF248 

     
    antibodies-online peptides for ZNF248

    ZNF248 Antibody Products:

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    antibodies-online antibodies for ZNF248 (21 products) 

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    Cloud-Clone Corp. ELISAs for ZNF248
    Cloud-Clone Corp. CLIAs for ZNF248
    Search eBioscience for ELISAs for ZNF248 
    antibodies-online kits for ZNF248 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR001909 Krueppel-associated_box
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q8NDW4

    ProtoNet protein and cluster: Q8NDW4

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN248_HUMAN, Q8NDW4
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 8 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with ZNF248           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN248_HUMAN, Q8NDW4
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF248           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZNF248

    miRNA
    Products:
        
    miRTarBase miRNAs that target ZNF248:
    hsa-mir-155-5p (MIRT020559), hsa-mir-215-5p (MIRT024704), hsa-mir-192-5p (MIRT026187)

    Block miRNA regulation of human, mouse, rat ZNF248 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZNF248 (see all 16):
    hsa-miR-124* hsa-miR-193a-3p hsa-miR-548d-3p hsa-miR-496 hsa-miR-181a-2* hsa-miR-3921 hsa-miR-3680 hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidZNF248 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZNF248
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF248

    Gene Editing
    Products:
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    Clone
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    GenScript: all cDNA clones in your preferred vector: ZNF248 (NM_021045)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF248
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF248

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF248


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN248_HUMAN, Q8NDW4: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZNF248           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF248 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF248           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF248
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF248
    Interactions:

        Search GeneGlobe Interaction Network for ZNF248

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with ZNF248           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF248 (ZN248)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF248 gene (5 alternative transcripts): 
    NM_001267597.1  NM_001267605.1  NM_001267606.1  NM_001267607.1  NM_021045.2  

    Unigene Cluster for ZNF248:

    Zinc finger protein 248
    Hs.528423  [show with all ESTs]
    Unigene Representative Sequence: NM_021045
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000485560(uc009xmc.2 uc001izb.3) ENST00000395867(uc001izc.3 uc001izd.1 uc010qeu.1)
    ENST00000494133 ENST00000374648 ENST00000395873 ENST00000395874 ENST00000357328

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZNF248 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZNF248 (see all 16):
    hsa-miR-124* hsa-miR-193a-3p hsa-miR-548d-3p hsa-miR-496 hsa-miR-181a-2* hsa-miR-3921 hsa-miR-3680 hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidZNF248 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZNF248
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF248
    Clone
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    OriGene clones in human, mouse for ZNF248 (see all 5)
    OriGene ORF clones in mouse, rat for ZNF248
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF248 (NM_021045)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF248
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF248
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF248
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF248
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF248
      QuantiFast Probe-based Assays in human, mouse, rat ZNF248

    Additional mRNA sequence: 

    AJ491695.1 AJ492196.1 AK293936.1 AK293971.1 AK299357.1 AL049341.1 BC021819.1 BC063550.1 
    BC110869.1 BC132915.1 BC132917.1 BC146820.1 

    9 DOTS entries:

    DT.452037  DT.95263794  DT.95255984  DT.100021973  DT.40217894  DT.95070840  DT.121284141  DT.121284153 
    DT.75134299 

    Selected AceView cDNA sequences (see all 94):

    CA394990 AJ491695 AA937912 BX488418 BM504619 BF002733 BM510679 BU622132 
    D81737 BG112912 AA810090 BX281220 AI057465 BX506883 AW028849 CD677607 
    AA648406 BC063550 CA394833 AJ492196 NM_021045 BX091339 BI916817 AI769668 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZNF248 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10
    SP1:                          -     -     -                       -                       -     -                           
    SP2:                                      -                       -                       -     -                           
    SP3:              -     -     -     -     -                       -                                                         
    SP4:                                      -                       -                                                         
    SP5:                                                              -                       -     -                 -         


    ECgene alternative splicing isoforms for ZNF248

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF248 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGAGGGGC
    ZNF248 Expression
    About this image

    ZNF248 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF248 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.528423
        Custom PCR Arrays for ZNF248
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF248

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZNF248 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp2481 , 5 zinc finger protein 2481, 5 79.51(n)1
    75.17(a)1
      6 (55.86 cM)5
    727201  NM_028335.21  NP_082611.11 
     1184273195 


    ENSEMBL Gene Tree for ZNF248 (if available)
    TreeFam Gene Tree for ZNF248 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF248 gene
    ZNF1752  ZNF6742  ZNF4872  ZNF5102  ZIM32  ZNF6142  ZNF1572  ZNF262  
    ZNF6132  ZNF812  ZNF6492  ENSG000002673602  ZNF7822  ZNF7932  ZNF252  ZNF5682  
    ENSG000002365752  ENSG000002296312  ZNF5672  ZNF1822  ZNF37A2  ZNF3002  ZNF3822  RBAK-RBAKDN2  
    Selected SIMAP similar genes for ZNF248 using alignment to 6 protein entries:     ZN248_HUMAN (see all proteins) (see all similar genes):
    FIK    ZFP90    ZNF625-ZNF20    ZNF124    ZNF10    ZNF844
    ZNF232    ZNF707    ZNF250    ZNF615    ZNF705A    ZNF625
    ZNF577    DKFZp666C237    ZNF323    ZNF705D    ZNF83    ZNF649

    Find genes that share paralogs with ZNF248           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ZNF248
    PGOHUM00000245870


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF248 (see all 1578)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs680477531,2
    C--37823144(-) CCACT-/TATTTA
            
    TATGA
    1 -- int11Minor allele frequency- TATTTA:0.00NA 2
    rs1474229741,2
    --38064993(+) TAAGGC/TGGCAC 1 -- ds50010--------
    rs1381156331,2
    --38064994(+) AAGGCA/GGCACC 1 -- ds50010--------
    rs13618941,2
    C,F,O,H--38065016(-) GATATG/AGGCCC 1 -- ds500115Minor allele frequency- A:0.04NA NS EA 1212
    rs1435841281,2
    --38065106(+) CTGGAA/GATAGA 1 -- ds50010--------
    rs1431504951,2
    --38065236(+) GAGACA/GTGGTC 1 -- ds50010--------
    rs1471768031,2
    --38065399(+) CTGACA/GACGTT 1 -- ds50010--------
    rs17422421,2
    C,F,O,H--38065451(+) AGGGCG/CCCTTC 1 -- ds500110Minor allele frequency- C:0.04NA NS EA 676
    rs714912031,2
    C,F--38065463(+) TCTTAC/ATTCAC 1 -- ut314Minor allele frequency- A:0.12NA CSA WA 124
    rs169375831,2
    C,F,H--38065606(+) AGGTTG/CGATGG 1 -- int18Minor allele frequency- C:0.06NA NS EA 680

    HapMap Linkage Disequilibrium report for ZNF248 (38091751 - 38147034 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZNF248:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1183366CNV Insertion17803354
    nsv895030CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF248
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF248

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZNF248           About GenesLikeMe

    Genetic Association Database (GAD): ZNF248
    Human Genome Epidemiology (HuGE) Navigator: ZNF248 (1 document)

    Export disorders for ZNF248 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF248 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZNF248)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p. (PubMed id 12566394)1, 2, 3 Guy J....Jackson M.S. (Genome Res. 2003)
    2. Common body mass index-associated variants confer risk of extreme obesity. (PubMed id 19553259)1, 4 Cotsapas C....Daly M.J. (Hum. Mol. Genet. 2009)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (Nature 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein. (PubMed id 15469996)9 Oh H.J.... Lau Y.-F.C. (Biol. Reprod. 2005)
    10. Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery. (PubMed id 19850934)9 Peng H....Rauscher F.J. (J. Biol. Chem. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57209 HGNC: 13041 AceView: ZNF248 Ensembl:ENSG00000198105 euGenes: HUgn57209
    ECgene: ZNF248 H-InvDB: ZNF248

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF248 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF248 gene:
    Search GeneIP for patents involving ZNF248

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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