Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF24 Gene

protein-coding   GIFtS: 59
GCID: GC18M032912

Zinc Finger Protein 24

(Previous name: zinc finger protein 24 (KOX 17))
(Previous symbol: ZNF191)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 241 2     Zinc Finger Protein KOX172 3
ZNF1911 2 3     KOX172 3
Zinc Finger Protein 24 (KOX 17)1 2     RSG-A2 3
Retinoic Acid Suppression Protein A2 3     ZSCAN32 3
Zinc Finger And SCAN Domain-Containing Protein 32 3     Zfp1912
Zinc Finger Protein 1912 3     Lacks Zinc Finger Domain2

External Ids:    HGNC: 130321   Entrez Gene: 75722   Ensembl: ENSG000001724667   OMIM: 1945345   UniProtKB: P170283   

Export aliases for ZNF24 gene to outside databases

Previous GC identifers: GC18M032950 GC18M032735 GC18M032722 GC18M031167 GC18M031169 GC18M029771


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZNF24 Gene: 
ZNF24 (zinc finger protein 24) is a protein-coding gene. Diseases associated with ZNF24 include esophageal adenocarcinoma, and fanconi's anemia. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF446.

UniProtKB/Swiss-Prot: ZNF24_HUMAN, P17028
Function: Transcription factor required for myelination of differentiated oligodendrocytes. Required for the
conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central
nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle.
Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro

Gene Wiki entry for ZNF24 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NT_010966.14  NC_018929.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF24 gene promoter:
         GATA-3   AML1a   ATF-2   Pax-6   Olf-1   GATA-2   GATA-1   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF24 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF24

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q12   Ensembl cytogenetic band:  18q12.2   HGNC cytogenetic band: 18q12

ZNF24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF24 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18M032912:  view genomic region     (about GC identifiers)

Start:
32,912,176 bp from pter      End:
32,925,446 bp from pter
Size:
13,271 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZNF24_HUMAN, P17028 (See protein sequence)
Recommended Name: Zinc finger protein 24  
Size: 368 amino acids; 42155 Da
Subcellular location: Nucleus
2 PDB 3D structures from and Proteopedia for ZNF24:
1X6E (3D)        3LHR (3D)    
Secondary accessions: O14754 Q53YE4 Q6ICR5 Q8IZN4
Alternative splicing: 2 isoforms:  P17028-1   P17028-2   

Explore the universe of human proteins at neXtProt for ZNF24: NX_P17028

Explore proteomics data for ZNF24 at MOPED 

Post-translational modifications:

  • UniProtKB: Sumoylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P17028

  • ZNF24 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZNF24 Protein Expression
    REFSEQ proteins: NP_008896.2  
    ENSEMBL proteins: 
     ENSP00000261332   ENSP00000467655   ENSP00000382015   ENSP00000467432   ENSP00000467608  
     ENSP00000467924  

    Human Recombinant Protein Products for ZNF24: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ZNF24
    OriGene Protein Over-expression Lysate for ZNF24
    OriGene MassSpec for ZNF24 
    OriGene Custom Protein Services for ZNF24
    GenScript Custom Purified and Recombinant Proteins Services for ZNF24
    Novus Biologicals ZNF24 Protein
    Novus Biologicals ZNF24 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF24 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    ZNF24 for ontologies           About GeneDecksing



    ZNF24 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for ZNF24
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZNF24
    GenScript Custom Superior Antibodies Services for ZNF24
    Novus Biologicals ZNF24 Antibodies
    Abcam antibodies for ZNF24
    Cloud-Clone Corp. Antibodies for ZNF24 
    Search ThermoFisher Antibodies for ZNF24
    LSBio Antibodies in human, mouse, rat for ZNF24 

    Assay Products for ZNF24: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ZNF24
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZNF24
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ZNF24 
    Cloud-Clone Corp. CLIAs for ZNF24


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    5 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR008916 Retrov_capsid_C
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2
     IPR003309 Tscrpt_reg_SCAN

    Graphical View of Domain Structure for InterPro Entry P17028

    ProtoNet protein and cluster: P17028

    2 Blocks protein domains:
    IPB003309 Transcriptional regulator SCAN
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZNF24_HUMAN, P17028
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 4 C2H2-type zinc fingers
    Similarity: Contains 1 SCAN box domain


    ZNF24 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZNF24_HUMAN, P17028
    Function: Transcription factor required for myelination of differentiated oligodendrocytes. Required for the
    conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central
    nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle.
    Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro

         Genatlas biochemistry entry for ZNF24:
    zinc finger protein 24 (KOX17) (C2H2 type,Kruppel-like)

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding TAS2288909
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding IPI16169070
    GO:0008270zinc ion binding NAS10585455
    GO:0043565sequence-specific DNA binding ISS--
         
    ZNF24 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF24:
     Decreased viability 

         5 MGI mutant phenotypes (inferred from 4 alleles(MGI details for Zfp191):
     behavior/neurological  cellular  embryogenesis  mortality/aging  nervous system 

    ZNF24 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for ZNF24: Zfp191tm1Jifu Zfp191tm1.2Pop

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZNF24 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZNF24

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF24 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF24 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF24
    8/127 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF24 (see all 127):
    hsa-miR-323-3p hsa-miR-579 hsa-miR-361-5p hsa-miR-640 hsa-miR-3152-3p hsa-miR-4272 hsa-miR-128 hsa-miR-578
    SwitchGear 3'UTR luciferase reporter plasmidZNF24 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZNF24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF24

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZNF24
    Sirion Biotech Customized adenovirus for overexpression of ZNF24

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ZNF24 (see all 8)
    OriGene ORF clones in mouse, rat for ZNF24
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF24 (NM_006965)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF24
    Sirion Biotech Customized lentivirus for stable overexpression of ZNF24 
                         Customized lentivirus expression plasmids for stable overexpression of ZNF24 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZNF24
    Search LifeMap BioReagents cell lines for ZNF24
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF24


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF24

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    5/67 Interacting proteins for ZNF24 (P170281, 2, 3 ENSP000002613324) via UniProtKB, MINT, STRING, and/or I2D (see all 67)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APLP1P516931, 2, 3EBI-707773,EBI-74648 MINT-63499 I2D: score=5 
    CCDC130P139942, 3, ENSP000002215544MINT-66902 I2D: score=5 STRING: ENSP00000221554
    SCAND1P570862, 3, ENSP000003019954MINT-68125 I2D: score=4 STRING: ENSP00000301995
    KAT5Q929932, 3MINT-63507 I2D: score=6 
    C14orf1Q9UKR52, 3MINT-63512 I2D: score=5 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0016032viral process ----
    GO:0042552myelination ISS--
    GO:0045892negative regulation of transcription, DNA-dependent IDA10585455

    ZNF24 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF24

    1 HMDB Compound for ZNF24    About this table
    CompoundSynonyms CAS #PubMed Ids
    ZincZinc (see all 2)7440-66-6--

    Search CenterWatch for drugs/clinical trials and news about ZNF24

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF24 gene: 
    NM_006965.2  

    Unigene Cluster for ZNF24:

    Zinc finger protein 24
    Hs.514802  [show with all ESTs]
    Unigene Representative Sequence: NM_006965
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000261332(uc002kyt.2 uc002kys.2) ENST00000589881 ENST00000399061(uc002kyu.1)
    ENST00000590140 ENST00000589539 ENST00000593130
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF24
    8/127 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF24 (see all 127):
    hsa-miR-323-3p hsa-miR-579 hsa-miR-361-5p hsa-miR-640 hsa-miR-3152-3p hsa-miR-4272 hsa-miR-128 hsa-miR-578
    SwitchGear 3'UTR luciferase reporter plasmidZNF24 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZNF24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF24
    Clone
    Products:
         
    OriGene clones in human, mouse for ZNF24 (see all 8)
    OriGene ORF clones in mouse, rat for ZNF24
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF24 (NM_006965)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF24
    Sirion Biotech Customized lentivirus for stable overexpression of ZNF24 
                         Customized lentivirus expression plasmids for stable overexpression of ZNF24 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ZNF24
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF24
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF24
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF24
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF24

    Additional mRNA sequence: 

    AF038964.1 AF542097.1 AK021966.1 AK291246.1 BC003566.1 BC016801.1 BT006658.1 CR450328.1 
    U68536.1 X52348.1 

    11 DOTS entries:

    DT.451808  DT.97840332  DT.434655  DT.100786941  DT.100786936  DT.85104811  DT.97864168  DT.121086002 
    DT.87018226  DT.95148951  DT.92434783 

    24/388 AceView cDNA sequences (see all 388):

    BQ425487 AU137984 AA336987 BI832574 BF513845 BX096673 BP351039 AA223585 
    BX090150 BQ269370 CA392930 BU150089 CD722986 N28492 AA363340 BC003566 
    AU117164 BM711446 AI627867 BP355207 AA447098 CB241173 H30495 AK021966 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF24    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b
    SP1:              -     -     -                                       
    SP2:                    -     -                                       
    SP3:                          -                                       
    SP4:                                                                  


    ECgene alternative splicing isoforms for ZNF24

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF24 expression in normal human tissues (normalized intensities)      ZNF24 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGTTCCTGG
    ZNF24 Expression
    About this image


    ZNF24 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Kidney (Urinary System)
             renal vesicle e12.5   
     
     Bone (Muscoskeletal System)
             mandibular prominence tissue e10.0   
     
     Head Mesenchyme (Muscoskeletal System)
             mandibular prominence tissue e10.0   
     
     Neural Tube (Nervous System)
             Primitive Spinal Cord

    See ZNF24 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF24

    SOURCE GeneReport for Unigene cluster: Hs.514802

    UniProtKB/Swiss-Prot: ZNF24_HUMAN, P17028
    Tissue specificity: Expressed in many tissues except in heart

        SABiosciences Custom PCR Arrays for ZNF24
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ZNF24
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF24
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF24
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF24
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF24
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF24

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZNF24 gene from 1/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp1911 , 5 zinc finger protein 1911, 5 89.04(n)1
    95.11(a)1
      18 (12.55 cM)5
    590571  NM_021559.21  NP_067534.21 
     240097025 


    ENSEMBL Gene Tree for ZNF24 (if available)
    TreeFam Gene Tree for ZNF24 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF24 gene
    ZNF4462  ZSCAN92  ZKSCAN12  ZNF3972  ZNF2322  ZSCAN302  ZNF1742  ZNF32  
    ZKSCAN42  ZNF3962  ZSCAN122  ZNF3942  ZSCAN232  ZSCAN212  ZNF1652  ZSCAN162  
    ZKSCAN82  ZSCAN222  ZSCAN312  ZKSCAN32  ZNF182  
    18/281 SIMAP similar genes for ZNF24 using alignment to 4 protein entries:     ZNF24_HUMAN (see all proteins) (see all similar genes):
    ZNF818P    ZNF78L1    DKFZp666C237    ZNF470    ZSCAN20    ZNF167
    ZFS-4    ZNF286B    ZNF300    ZNF329    ZNF551    ZNF79
    DKFZp761O1618    ZFP41    ZIK1    ZNF271    ZNF34    ZNF572

    ZNF24 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/283 SNPs in ZNF24 are shown (see all 283)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs175605351,2
    C,F--32911760(+) TGACAT/CAGAGC 1 -- ds500111Minor allele frequency- C:0.23NA WA CSA EA 507
    rs1888900121,2
    --32911789(+) ATAGAA/GAAGAG 1 -- ds50010--------
    rs1167728651,2
    C--32911837(+) TTCACA/GTCTTG 1 -- ds50010--------
    rs129644901,2
    C,F,H--32912034(+) AAGAAT/GAAGAA 1 -- ds50018Minor allele frequency- G:0.27NS NA WA EA 472
    rs1930829391,2
    --32912349(+) ACTTTA/CTTGGC 1 -- ut310--------
    rs1831348001,2
    --32912457(+) TTCTGA/CTAGCA 1 -- ut310--------
    rs1874684971,2
    --32912726(+) GTTGTG/TTTACC 1 -- ut310--------
    rs749190421,2
    C--32912814(+) ACAAAA/CAATCC 1 -- ut310--------
    rs1441755801,2
    C--32912855(+) AAAAT-/AACCCC 1 -- ut310--------
    rs1918386081,2
    --32912898(+) TGCAAA/GATAAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for ZNF24 (32912176 - 32925446 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZNF24: --

    Human Gene Mutation Database (HGMD): ZNF24
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF24
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF24

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 194534    OMIM disorders: --

    7 diseases for ZNF24:    About MalaCards
    esophageal adenocarcinoma    fanconi's anemia    anemia    esophagitis
    adenocarcinoma    hepatocellular carcinoma    leukemia


    ZNF24 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ZNF24
    Human Genome Epidemiology (HuGE) Navigator: ZNF24 (1 document)

    Export disorders for ZNF24 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF24 gene, integrated from 9 sources (see all 43):
    (articles sorted by number of sources associating them with ZNF24)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (2010)
    2. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (2005)
    3. Systematic identification and analysis of mammalian small ubiquitin- like modifier substrates. (PubMed id 15561718)1, 2 Gocke C.B.... Kang J. (2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Molecular cloning of six novel Kruppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB. (PubMed id 10585455)1, 2 Han Z.-G.... Chen Z. (1999)
    7. Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (1990)
    8. Chromosomal localization of two human zinc finger protein genes, ZNF24 (KOX17) and ZNF29 (KOX26), to 18q12 and 17p13-p12, respectively. (PubMed id 2004757)1, 9 Rousseau-Merck M.F....Thiesen H.J. (1991)
    9. Zinc finger protein 191 (ZNF191/Zfp191) is necessary to maintain neural cells as cycling progenitors. (PubMed id 19544452)1, 9 Khalfallah O....Nardelli J. (2009)
    10. A transcript profiling approach reveals the zinc fing er transcription factor ZNF191 is a pleiotropic factor. (PubMed id 19463170)1, 9 Li J....Zhang J. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7572 HGNC: 13032 AceView: ZNF24 Ensembl:ENSG00000172466 euGenes: HUgn7572
    ECgene: ZNF24 H-InvDB: ZNF24

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF24 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF24 gene:
    Search GeneIP for patents involving ZNF24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for ZNF24 (ZNF24)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ZNF24  
     OriGene qPCR primer pairs and template standards for ZNF24   OriGene Protein Over-expression Lysate for ZNF24  
     OriGene MassSpec something-or-other for ZNF24   OriGene clones in human, mouse for ZNF24  
     OriGene qSTAR qPCR primer pairs in human, mouse for ZNF24   OriGene Purified Protein for ZNF24  
     OriGene ORF clones in mouse, rat for ZNF24   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZNF24   OriGene Custom Protein Services for ZNF24  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF24
     QIAGEN SeqTarget long-range PCR primers for resequencing ZNF24
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF24
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF24
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF24
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF24
     GenScript Custom Purified and Recombinant Proteins Services for ZNF24 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF24
     GenScript Custom Assay Services for ZNF24 GenScript Custom Superior Antibodies Services for ZNF24
     GenScript Custom overexpressing Cell Line Services for ZNF24 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZNF24 promoter
     Search Chromatin IP Primers for ZNF24
     RT2 qPCR Primer Assay in human, mouse, rat ZNF24
     Search GNC Networks for ZNF24
     SABiosciences Custom PCR Arrays for ZNF24
     Search Tocris compounds for ZNF24
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZNF24 antibodies
     ZNF24 proteins
     ZNF24 lysates
     Antibodies for ZNF24
     See all of Abcam's Antibodies, Kits and Proteins for ZNF24
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ZNF24
     Antibodies for ZNF24
     ELISAs for ZNF24
     CLIAs for ZNF24
     Search LifeMap BioReagents cell lines for ZNF24
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF24
     SwitchGear 3'UTR luciferase reporter plasmids for ZNF24
     SwitchGear Promoter luciferase reporter plasmids for ZNF24
     Search ThermoFisher Antibodies for ZNF24
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF24
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ZNF24
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZNF24
    Customized:
     lentivirus for stable overexpression of ZNF24
     lentivirus expression plasmids for stable overexpression of ZNF24
     adenovirus for overexpression of ZNF24
     LSBio Antibodies in human, mouse, rat for ZNF24
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZNF24 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4