Aliases for ZNF236 Gene
External Ids for ZNF236 Gene
- HGNC: 13028
- Entrez Gene: 7776
- Ensembl: ENSG00000130856
- OMIM: 604760
- UniProtKB: Q9UL36
Previous GeneCards Identifiers for ZNF236 Gene
- GC18P074159
- GC18P074689
- GC18P074299
- GC18P072663
- GC18P074536
- GC18P071217
Summaries for ZNF236 Gene
GeneCards Summary for ZNF236 Gene
ZNF236 (Zinc Finger Protein 236) is a Protein Coding gene. Diseases associated with ZNF236 include Type 1 Diabetes Mellitus 6. Gene Ontology (GO) annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZFAT.
UniProtKB/Swiss-Prot for ZNF236 Gene
-
May be involved in transcriptional regulation.
Additional gene information for ZNF236 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF236 Gene
Genomics for ZNF236 Gene
GeneHancer (GH) Regulatory Elements for ZNF236 Gene
Regulatory Element Products
Genomic Locations for ZNF236 Gene
- chr18:76,822,561-76,970,732
- (GRCh38/hg38)
- Size:
- 148,172 bases
- Orientation:
- Plus strand
- chr18:74,534,563-74,682,683
- (GRCh37/hg19)
Genomic View for ZNF236 Gene
- Cytogenetic band:
-
- 18q23 by Ensembl
- 18q23 by Entrez Gene
- 18q22-q23 by HGNC


RefSeq DNA sequence for ZNF236 Gene
Proteins for ZNF236 Gene
-
Protein details for ZNF236 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UL36-ZN236_HUMAN
- Recommended name:
- Zinc finger protein 236
- Protein Accession:
- Q9UL36
- B2RTX9
- Q9UL37
Protein attributes for ZNF236 Gene
- Size:
- 1845 amino acids
- Molecular mass:
- 203704 Da
- Quaternary structure:
- No Data Available
Protein Expression for ZNF236 Gene
Post-translational modifications for ZNF236 Gene
Other Protein References for ZNF236 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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Assay Products
No data available for DME Specific Peptides for ZNF236 Gene
Domains & Families for ZNF236 Gene
Gene Families for ZNF236 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Transcription factors
Protein Domains for ZNF236 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF236 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UL36- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
Function for ZNF236 Gene
Molecular function for ZNF236 Gene
- GENATLAS Biochemistry:
- zinc finger protein 236,(glucose regulated Kruppel-like),ubiquitously expressed
- UniProtKB/Swiss-Prot Function:
- May be involved in transcriptional regulation.
Phenotypes From GWAS Catalog for ZNF236 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003677 | DNA binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ZNF236 Gene
- GenomeRNAi human phenotypes for ZNF236:
Animal Model Products
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-
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miRNA for ZNF236 Gene
- miRTarBase miRNAs that target ZNF236
-
- hsa-mir-155-5p (MIRT005091)
- hsa-mir-142-3p (MIRT021570)
- hsa-mir-132-3p (MIRT021847)
- hsa-mir-128-3p (MIRT021965)
- hsa-let-7e-5p (MIRT051497)
- hsa-mir-4732-5p (MIRT450522)
- hsa-mir-4668-5p (MIRT450523)
- hsa-mir-3148 (MIRT450524)
- hsa-mir-6783-5p (MIRT450525)
- hsa-mir-548n (MIRT450526)
- hsa-mir-6872-3p (MIRT719764)
- hsa-mir-670-3p (MIRT719765)
- hsa-mir-6836-3p (MIRT719766)
- hsa-mir-7162-5p (MIRT719767)
- hsa-mir-516b-3p (MIRT719768)
- hsa-mir-516a-3p (MIRT719769)
- hsa-mir-2115-5p (MIRT719770)
- hsa-mir-222-3p (MIRT719771)
- hsa-mir-221-3p (MIRT719772)
- hsa-mir-6829-3p (MIRT719773)
- hsa-mir-6791-3p (MIRT719774)
- hsa-mir-6778-3p (MIRT719775)
- hsa-mir-1976 (MIRT719776)
- hsa-mir-4797-3p (MIRT719777)
- hsa-mir-6893-3p (MIRT719778)
- hsa-mir-370-3p (MIRT719779)
- hsa-mir-660-3p (MIRT719780)
miRNA Products
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF236 Gene
Localization for ZNF236 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF236 Gene
- Nucleus.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for ZNF236 Gene
Pathways & Interactions for ZNF236 Gene
Interacting Proteins for ZNF236 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006351 | transcription, DNA-templated | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
GO:0071333 | cellular response to glucose stimulus | IEP | 9299475 |
No data available for Pathways by source and SIGNOR curated interactions for ZNF236 Gene
Transcripts for ZNF236 Gene
mRNA/cDNA for ZNF236 Gene
- (7) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (66) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZNF236 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZNF236
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-
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-
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miRNA Products
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Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for ZNF236
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for ZNF236 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF236 Gene
NURSA nuclear receptor signaling pathways regulating expression of ZNF236 Gene:
ZNF236SOURCE GeneReport for Unigene cluster for ZNF236 Gene:
Hs.719137mRNA Expression by UniProt/SwissProt for ZNF236 Gene:
Q9UL36-ZN236_HUMANEvidence on tissue expression from TISSUES for ZNF236 Gene
- Kidney(4.1)
Primer Products
-
OriGene qPCR primer pairs for ZNF236
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF236 Gene
Orthologs for ZNF236 Gene
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | ZNF236 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | ZNF236 33 |
|
||
-- 34 |
|
ManyToMany | |||
rat (Rattus norvegicus) |
Mammalia | Zfp236 33 |
|
||
mouse (Mus musculus) |
Mammalia | Zfp236 33 16 34 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | ZNF236 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | ZNF236 34 |
|
OneToOne | |
cow (Bos Taurus) |
Mammalia | ZNF236 33 34 |
|
||
chicken (Gallus gallus) |
Aves | ZNF236 33 34 |
|
||
lizard (Anolis carolinensis) |
Reptilia | ZNF236 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | znf236 33 |
|
||
Str.17000 33 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.5283 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | znf236 34 |
|
OneToOne | |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | FZF1 34 |
|
OneToMany |
- Species where no ortholog for ZNF236 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ZNF236 Gene
(98) SIMAP similar genes for ZNF236 Gene using alignment to 3 proteins:
- ZNF826P
- kr-znf3
- ZNF808
- ZNF78L1
- ZNF55
- ZFS-4
- ZFS-5
- HZF16
- ZNF
- DKFZp686N0199
- ZNF468
- DKFZp434J0650
- ZNF430
- ZFS-6
- ZNF785
- ZFS-2
- ZNF22
- ZNF737
- ZNFN1A2
- ZNF263
- KLF1
- ZNF516
- ZNF72
- ZFX
- ZNF410
- ZNF702P
- ZNF219
- KLF4
- KLF13
- BCL6B
- DKFZp547H249
- ZNF818P
- RREB1
- ZNF600
- A-328A3.4
- ZNF696
- ZNF692
- ZNF844
- ZNF585A
- ZKSCAN1
- ZNF697
- ZNF521
- DKFZp686O1631
- ZNF770
- PLZF
- ZNF25
- ZNF146
- ZFP64
- DKFZp666C237
- MAZ
- GTF3A
- GZF1
- ZNF79
- ZNF672
- ZNF558
- ZNF154
- ZFP1
- WT1
- ZNF883
- ZNF391
- ZNF286A
- ZNF35
- ZNF83
- ZNF557
- ZSCAN31
- ZNF773
- ZNF684
- ZNF664
- ZNF581
- ZNF570
- ZNF564
- ZNF56
- ZNF449
- ZNF436
- ZNF324
- ZNF323
- PLAGL1
- DKFZp434G1930
- DKFZp313M0722
- ZFP41
- DKFZp686G16228
- ZNF485
- smap-7
- ZNF578
- ZSCAN21
- ZNF586
- ZNF547
- ZNF708
- ZNF2
- ZNF137P
- REST
- OVOL1
- Nbla00121
- HZF41
- HZF40
- HZF30
- DKFZp686O111
- DKFZp686D2168
Variants for ZNF236 Gene
SNP ID | Clin | Chr 18 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000048008 | -- | 76,862,900(+) | A/G | intron_variant | |
rs1000054036 | -- | 76,958,673(+) | T/C | genic_downstream_transcript_variant, intron_variant | |
rs1000060421 | -- | 76,936,476(+) | T/C | genic_downstream_transcript_variant, intron_variant | |
rs1000078624 | -- | 76,862,699(+) | A/G | intron_variant | |
rs1000121419 | -- | 76,949,701(+) | C/A | genic_downstream_transcript_variant, intron_variant |
Additional Variant Information for ZNF236 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF236 Gene
Disorders for ZNF236 Gene
Disorder | Aliases | PubMed IDs |
---|---|---|
type 1 diabetes mellitus 6 |
|
|
Additional Disease Information for ZNF236
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF236 Gene
Publications for ZNF236 Gene
- Cloning and characterization of ZNF236, a glucose-regulated Kruppel-like zinc-finger gene mapping to human chromosome 18q22-q23. (PMID: 10458916) Holmes DI … Mason RM (Genomics 1999) 2 3 4 58
- Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G … Wijmenga C (Gut 2009) 3 44 58
- Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping. (PMID: 19690890) McDonough CW … Bowden DW (Human genetics 2009) 3 44 58
- A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein MY … Mann M (Cell 2015) 3 58
- Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. (PMID: 23648065) Low SK … Nakamura Y (Cancer science 2013) 3 58
Products for ZNF236 Gene
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Sources for ZNF236 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew