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Aliases for ZNF236 Gene

Aliases for ZNF236 Gene

  • Zinc Finger Protein 236 2 3
  • Regulated By Glucose 3
  • ZNF236A 3
  • ZNF236B 3

External Ids for ZNF236 Gene

Summaries for ZNF236 Gene

GeneCards Summary for ZNF236 Gene

ZNF236 (Zinc Finger Protein 236) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is SALL3.

UniProtKB/Swiss-Prot for ZNF236 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF236 Gene

Genomics for ZNF236 Gene

Genomic Location for ZNF236 Gene

Start:
76,822,582 bp from pter
End:
76,970,732 bp from pter
Size:
148,151 bases
Orientation:
Plus strand

Genomic View for ZNF236 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF236 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF236 Gene

No data available for Regulatory Elements for ZNF236 Gene

Proteins for ZNF236 Gene

  • Protein details for ZNF236 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UL36-ZN236_HUMAN
    Recommended name:
    Zinc finger protein 236
    Protein Accession:
    Q9UL36
    Secondary Accessions:
    • B2RTX9
    • Q9UL37

    Protein attributes for ZNF236 Gene

    Size:
    1845 amino acids
    Molecular mass:
    203704 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF236 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF236 Gene

Proteomics data for ZNF236 Gene at MOPED

Post-translational modifications for ZNF236 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF236 Gene

No data available for DME Specific Peptides for ZNF236 Gene

Domains for ZNF236 Gene

Gene Families for ZNF236 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF236 Gene

UniProtKB/Swiss-Prot:

ZN236_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9UL36
Similarity:
  • Contains 30 C2H2-type zinc fingers.:
    • Q9UL36
genes like me logo Genes that share domains with ZNF236: view

Function for ZNF236 Gene

Molecular function for ZNF236 Gene

GENATLAS Biochemistry: zinc finger protein 236,(glucose regulated Kruppel-like),ubiquitously expressed
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF236 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF236: view

miRNA for ZNF236 Gene

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF236 Gene

Localization for ZNF236 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF236 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF236 Gene COMPARTMENTS Subcellular localization image for ZNF236 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF236 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF236: view

Pathways for ZNF236 Gene

SuperPathways for ZNF236 Gene

No Data Available

Interacting Proteins for ZNF236 Gene

Gene Ontology (GO) - Biological Process for ZNF236 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0071333 cellular response to glucose stimulus IEP 9299475
genes like me logo Genes that share ontologies with ZNF236: view

No data available for Pathways by source for ZNF236 Gene

Transcripts for ZNF236 Gene

Unigene Clusters for ZNF236 Gene

Zinc finger protein 236:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF236 Gene

No ASD Table

Relevant External Links for ZNF236 Gene

GeneLoc Exon Structure for
ZNF236
ECgene alternative splicing isoforms for
ZNF236

Expression for ZNF236 Gene

mRNA expression in normal human tissues for ZNF236 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF236 Gene

SOURCE GeneReport for Unigene cluster for ZNF236 Gene Hs.719137

mRNA Expression by UniProt/SwissProt for ZNF236 Gene

Q9UL36-ZN236_HUMAN
Tissue specificity: Ubiquitous. Expression levels are highest in skeletal muscle and brain, intermediate in heart, pancreas, and placenta, and lowest in kidney, liver, and lung
genes like me logo Genes that share expressions with ZNF236: view

Orthologs for ZNF236 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZNF236 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF236 36
  • 99.29 (n)
  • 99.67 (a)
ZNF236 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF236 36
  • 79.92 (n)
  • 81.57 (a)
ZNF236 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 17 (a)
ManyToMany
ZNF236 36
  • 86.71 (n)
  • 90.86 (a)
mouse
(Mus musculus)
Mammalia Zfp236 36
  • 83.39 (n)
  • 88.66 (a)
Zfp236 16
Zfp236 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF236 37
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF236 37
  • 80 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp236 36
  • 83.79 (n)
  • 88.51 (a)
chicken
(Gallus gallus)
Aves ZNF236 36
  • 74.84 (n)
  • 84.02 (a)
ZNF236 37
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF236 37
  • 78 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.5283 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17000 36
znf236 36
  • 70.44 (n)
  • 73.8 (a)
zebrafish
(Danio rerio)
Actinopterygii znf236 37
  • 56 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FZF1 37
  • 23 (a)
OneToMany
Species with no ortholog for ZNF236:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF236 Gene

ENSEMBL:
Gene Tree for ZNF236 (if available)
TreeFam:
Gene Tree for ZNF236 (if available)

Paralogs for ZNF236 Gene

Paralogs for ZNF236 Gene

genes like me logo Genes that share paralogs with ZNF236: view

Variants for ZNF236 Gene

Sequence variations from dbSNP and Humsavar for ZNF236 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs470129 -- 76,951,725(+) taata(A/G)tttga intron-variant
rs470133 -- 76,955,270(+) GGGCA(C/T)GATGG intron-variant
rs470198 -- 76,944,447(+) TGAGT(A/T)TAGCT intron-variant
rs470216 -- 76,945,137(+) ttgct(A/G)tttca intron-variant
rs470220 -- 76,968,697(+) AACAT(G/T)GAAAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF236 Gene

Variant ID Type Subtype PubMed ID
esv2717388 CNV Deletion 23290073
esv268598 CNV Insertion 20981092
nsv909946 CNV Gain 21882294
esv2717421 CNV Deletion 23290073
esv2547601 CNV Insertion 19546169
esv2717422 CNV Deletion 23290073
nsv2363 CNV Insertion 18451855
esv2625456 CNV Insertion 19546169
esv2588513 CNV Deletion 19546169
esv2717423 CNV Deletion 23290073

Relevant External Links for ZNF236 Gene

HapMap Linkage Disequilibrium report
ZNF236
Human Gene Mutation Database (HGMD)
ZNF236

Disorders for ZNF236 Gene

Relevant External Links for ZNF236

Genetic Association Database (GAD)
ZNF236
Human Genome Epidemiology (HuGE) Navigator
ZNF236
genes like me logo Genes that share disorders with ZNF236: view

No data available for UniProtKB/Swiss-Prot for ZNF236 Gene

Publications for ZNF236 Gene

  1. Cloning and characterization of ZNF236, a glucose-regulated kruppel- like zinc-finger gene mapping to human chromosome 18q22-q23. (PMID: 10458916) Holmes D.I. … Mason R.M. (Genomics 1999) 2 3 4
  2. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PMID: 19240061) Trynka G. … Wijmenga C. (Gut 2009) 3 49
  3. Genetic analysis of diabetic nephropathy on chromosome 18 in African Americans: linkage analysis and dense SNP mapping. (PMID: 19690890) McDonough C.W. … Bowden D.W. (Hum. Genet. 2009) 3 49
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. (PMID: 23648065) Low S.K. … Nakamura Y. (Cancer Sci. 2013) 3

Products for ZNF236 Gene

Sources for ZNF236 Gene

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