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Aliases for ZNF234 Gene

Aliases for ZNF234 Gene

  • Zinc Finger Protein 234 2 3
  • Zinc Finger Protein HZF4 3 4
  • Zinc Finger Protein 269 3 4
  • ZNF269 3 4
  • Zinc Finger Protein 234, Partial Sequence 3
  • C2-H2 Type Zinc Finger Protein 3
  • Homo Sapiens Zinc Finger 234 3
  • Zinc Finger Protein 4 3
  • HZF4 3

External Ids for ZNF234 Gene

Previous Symbols for ZNF234 Gene

  • ZNF269

Summaries for ZNF234 Gene

GeneCards Summary for ZNF234 Gene

ZNF234 (Zinc Finger Protein 234) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF155.

UniProtKB/Swiss-Prot for ZNF234 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF234 Gene

Genomics for ZNF234 Gene

Genomic Location for ZNF234 Gene

Start:
44,141,557 bp from pter
End:
44,160,309 bp from pter
Size:
18,753 bases
Orientation:
Plus strand

Genomic View for ZNF234 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF234 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF234 Gene

Regulatory Elements for ZNF234 Gene

Proteins for ZNF234 Gene

  • Protein details for ZNF234 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14588-ZN234_HUMAN
    Recommended name:
    Zinc finger protein 234
    Protein Accession:
    Q14588
    Secondary Accessions:
    • A8K1C8
    • Q96IR4
    • Q9NS45
    • Q9NYT7

    Protein attributes for ZNF234 Gene

    Size:
    700 amino acids
    Molecular mass:
    80560 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF234 Gene

Proteomics data for ZNF234 Gene at MOPED

Post-translational modifications for ZNF234 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys482 and Lys485

Other Protein References for ZNF234 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF234 Gene

Domains for ZNF234 Gene

Gene Families for ZNF234 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF234 Gene

UniProtKB/Swiss-Prot:

ZN234_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q14588
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q14588
Similarity:
  • Contains 19 C2H2-type zinc fingers.:
    • Q14588
genes like me logo Genes that share domains with ZNF234: view

Function for ZNF234 Gene

Molecular function for ZNF234 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF234 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF234: view

Phenotypes for ZNF234 Gene

GenomeRNAi human phenotypes for ZNF234:
genes like me logo Genes that share phenotypes with ZNF234: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF234 Gene

Localization for ZNF234 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF234 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF234 Gene COMPARTMENTS Subcellular localization image for ZNF234 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF234 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with ZNF234: view

Pathways for ZNF234 Gene

SuperPathways for ZNF234 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF234: view

Pathways by source for ZNF234 Gene

2 Reactome pathways for ZNF234 Gene

Gene Ontology (GO) - Biological Process for ZNF234 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF234: view

Transcripts for ZNF234 Gene

Unigene Clusters for ZNF234 Gene

Zinc finger protein 234:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF234 Gene

No ASD Table

Relevant External Links for ZNF234 Gene

GeneLoc Exon Structure for
ZNF234
ECgene alternative splicing isoforms for
ZNF234

Expression for ZNF234 Gene

mRNA expression in normal human tissues for ZNF234 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF234 Gene

SOURCE GeneReport for Unigene cluster for ZNF234 Gene Hs.235992

genes like me logo Genes that share expressions with ZNF234: view

Orthologs for ZNF234 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF234 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF234 36
  • 99.48 (n)
  • 99.43 (a)
ZNF234 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF234 36
  • 86.84 (n)
  • 83.95 (a)
dog
(Canis familiaris)
Mammalia ZNF234 36
  • 83.07 (n)
  • 77.47 (a)
ZNF234 37
  • 78 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG10147 38
  • 32 (a)
CG7963 38
  • 34 (a)
CG10669 38
  • 25 (a)
CG2120 38
  • 36 (a)
EG:95B7.7 38
  • 35 (a)
CG17803 38
  • 33 (a)
CG8301 38
  • 29 (a)
CG9215 38
  • 43 (a)
CG5245 38
  • 42 (a)
CG6254 38
  • 33 (a)
CG17568 38
  • 36 (a)
CG6689 38
  • 36 (a)
CG7386 38
  • 31 (a)
Species with no ortholog for ZNF234:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF234 Gene

ENSEMBL:
Gene Tree for ZNF234 (if available)
TreeFam:
Gene Tree for ZNF234 (if available)

Paralogs for ZNF234 Gene

Selected SIMAP similar genes for ZNF234 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF234: view

Variants for ZNF234 Gene

Sequence variations from dbSNP and Humsavar for ZNF234 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1106562 -- 44,151,980(+) ggggg(A/T)tgatt intron-variant
rs1113557 -- 44,156,444(+) TCACA(C/G)AGGAC reference, missense
rs2141524 -- 44,160,613(+) TTTTC(C/T)ATTTT downstream-variant-500B
rs2293587 - 44,148,801(+) CTGTG(A/G)TCTTC missense, reference
rs2356751 -- 44,145,437(+) ATCAA(C/T)TCTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF234 Gene

Variant ID Type Subtype PubMed ID
nsv833840 CNV Gain 17160897
esv2718616 CNV Deletion 23290073
dgv567e201 CNV Deletion 23290073
esv2718617 CNV Deletion 23290073

Relevant External Links for ZNF234 Gene

HapMap Linkage Disequilibrium report
ZNF234

Disorders for ZNF234 Gene

No disorders were found for ZNF234 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF234 Gene

Publications for ZNF234 Gene

  1. Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PMID: 7865130) Abrink M. … Hellman L. (DNA Cell Biol. 1995) 2 3 4
  2. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. (PMID: 18624398) Wang J. … He F. (J. Proteome Res. 2008) 3

Products for ZNF234 Gene

  • antibodies-online peptides for ZNF234
  • antibodies-online antibodies for ZNF234
  • antibodies-online kits for ZNF234

Sources for ZNF234 Gene

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