ZNF234 Gene
protein-coding GIFtS: 45
GCID: GC19P044645
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zinc finger protein 234
(Previous symbol: ZNF269)
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Aliases
for ZNF234 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 2341 2 | | C2-H2 Type Zinc Finger Protein2 | | ZNF2691 2 3 | | Homo Sapiens Zinc Finger 2342 | | HZF41 2 | | Zinc Finger Protein 234, Partial Sequence2 | | Zinc Finger Protein 2692 3 | | Zinc Finger Protein 42 | | Zinc Finger Protein HZF42 3 | | |
Export aliases for ZNF234 gene to outside databasesPrevious GC identifers: GC19P045291 GC19P045037 GC19P049321 GC19P049337 GC19P041077 |
Summaries
for ZNF234 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN234_HUMAN, Q14588Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF234 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF234 gene promoter:
C/EBPbeta LCR-F1 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF234
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF234 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.31 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13ZNF234 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P044645: view genomic region
(about GC identifiers)
Start:
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44,645,710 bp from pter |
End:
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44,664,462 bp from pter |
Size:
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18,753 bases |
Orientation:
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plus strand |
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Proteins
for ZNF234 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN234_HUMAN, Q14588 (See
protein sequence)Recommended Name: Zinc finger protein 234 Size: 700 amino acids; 80560 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: A8K1C8 Q96IR4 Q9NS45 Q9NYT7Explore the universe of human proteins at neXtProt for ZNF234: NX_Q14588
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14588
ZNF234 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001138296.1 NP_006621.1
ENSEMBL proteins: ENSP00000465011 ENSP00000400878 ENSP00000466129 Reactome Protein details: Q14588
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IDA | -- |
ZNF234 for ontologies About GeneDecksing
ZNF234 Antibody Products:
Assay Products for ZNF234: |
Protein
Domains /
Families
for ZNF234 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF234 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q14588ProtoNet protein and cluster: Q14588 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN234_HUMAN, Q14588Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 19 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF234 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN234_HUMAN, Q14588Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF234 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF234 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ZNF234 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF234 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF234 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF234 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF234:
|
Pathways & Interactions
for ZNF234 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF234
ZNF234 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF234
1 Interacting protein for ZNF234 (Q145883) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF234 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF234 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF234
Search CenterWatch for drugs/clinical trials and news about ZNF234 / ZN234
|
Transcripts
for ZNF234 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF234 gene (2 alternative transcripts): NM_001144824.1 NM_006630.2 Unigene Cluster for ZNF234: Zinc finger protein 234 Hs.235992 [show with all ESTs]Unigene Representative Sequence: NM_0066304 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000592437 ENST00000426739(uc002oym.3 uc002oyl.4) ENST00000590795
ENST00000590748
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF234 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF234 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF234 (NM_006630) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF234 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF234 |
Additional cDNA sequence: AF027141.1 AF027142.1 AF027143.1 AF228417.1 AK289843.1 AK314064.1 BC007303.1 X78927.1 6 DOTS entries: DT.40203954 DT.75155377 DT.97791333 DT.86836999 DT.100686551 DT.101970046 24/170 AceView cDNA sequences (see all 170): CK903516 AW005759 NM_006630 BC024197 BE299132 AA234283 M78106 AA053288 CF619307 BX091242 BC007303 AY166788 AI186403 BU949912 AK023091 AH012544 CA942750 BQ680058 AI698737 BU608030 X78927 AI151209 AY166787 C21274
GeneLoc Exon Structure
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Expression
for ZNF234 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF234 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF234 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF234
SOURCE GeneReport for Unigene cluster: Hs.235992
SABiosciences Custom PCR Arrays for ZNF234
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF234
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF234 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF234 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF234 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF234 |
Orthologs
for ZNF234 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF234 (if available)
TreeFam Gene Tree for ZNF234 (if available) |
Paralogs
for ZNF234 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF234 gene
- ZNF2292 ZNF2232 ZNF2302 ENSG000000623702 ZNF1552 ZNF6642 ZNF2272 ZNF2392
- ZNF2242 ZNF2252 ZNF2262 ZNF2142 ZNF2222 ZNF2842 ENSG000002671732 ZNF452
- ZNF2352 ZNF2212 ENSG000002670222 ZNF2852 ZNF2332
18/577 SIMAP similar genes for ZNF234 using alignment to 4 protein entries: ZN234_HUMAN (see all proteins)
(see all similar genes):ZNF226 ZNF224 ZNF225 ZNF230 ZNF235 ZNF155
ZNF221 ZNF233 ZNF818P ZNF789 ZNF222 ZFP90
ZNF595 MGC12518 ZSCAN16 ZNF658 ZNF658B ZNF589
ZNF234 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF234 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF234 (44645710 - 44664462 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF234: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF234 |
|
Disorders
/ Diseases
for ZNF234 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF234 for disorders About MalaCards
ZNF234 for disorders About GeneDecksing
OMIM gene information: 604750
OMIM disorders: --
Export disorders for ZNF234 gene to outside databases
|
Publications
for ZNF234 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF234 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF234) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PubMed id 7865130)1, 2, 3 Abrink M.... Hellman L. (1995)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PubMed id 12743021)1, 2 Shannon M.... Stubbs L. (2003)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. (PubMed id 18624398)1 Wang J....He F. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ZNF234 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF234 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF234 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF234 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF234 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF234 gene:
Search GeneIP for patents involving ZNF234
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF234 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF234 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF234 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF234 | | | OriGene Protein Over-expression Lysate for ZNF234 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF234 | | OriGene 3'-UTR Clone for ZNF234 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF234 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF234 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | ZNF234 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF234 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF234 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF234 |
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