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Aliases for ZNF233 Gene

Aliases for ZNF233 Gene

  • Zinc Finger Protein 233 2 3 5

External Ids for ZNF233 Gene

Previous GeneCards Identifiers for ZNF233 Gene

  • GC19U900205
  • GC19P049446
  • GC19P044754
  • GC19P041196

Summaries for ZNF233 Gene

GeneCards Summary for ZNF233 Gene

ZNF233 (Zinc Finger Protein 233) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF112.

UniProtKB/Swiss-Prot for ZNF233 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF233 Gene

Genomics for ZNF233 Gene

Regulatory Elements for ZNF233 Gene

Enhancers for ZNF233 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F044259 0.9 ENCODE 24.9 +0.2 153 1.4 HDGF PKNOX1 ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2 ZNF302 ZNF416 ZNF180 ZNF45 ZNF234 ZNF224 ZNF284 ZNF225 ZNF230 EXOC3L2 XRCC1 ZNF233
GH19F044316 0.3 FANTOM5 18.8 +57.3 57254 0.3 KLF1 KLF17 ZNF233 ZNF229 ZNF112 ZNF221 ZNF285 ZNF223 ZNF284 ZNF180 ZNF227 PIR37551
GH19F044356 0.5 ENCODE 15 +96.9 96933 1.6 ATF1 CREB3L1 ARID4B SIN3A DMAP1 ZNF48 ETS1 YY1 SLC30A9 ELK1 ZNF233 BCAM ZNF234 EXOC3L2 NECTIN2 ZNF112 GC19M044340 PIR37551
GH19F044211 1 ENCODE 14.9 -47.2 -47182 1.7 CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF302 ZNF416 ZNF180 ZNF45 ZNF234 ZNF155 ZNF224 ZNF284 XRCC1 ENSG00000266958 NECTIN2 ZNF225
GH19F044206 0.4 ENCODE 14.6 -52.3 -52298 1.4 PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 ZNF2 YY1 ZNF302 CBX5 ZNF416 ZNF45 ZNF180 ZNF234 ZNF225 ZNF224 ZNF284 XRCC1 ZNF223 ZNF230 NECTIN2
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF233 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF233 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000347157 121 1200 HDGF PKNOX1 ARID4B SIN3A YBX1 FEZF1 DMAP1 ZNF2 ZNF302 ZNF416

Genomic Location for ZNF233 Gene

Chromosome:
19
Start:
44,259,880 bp from pter
End:
44,275,317 bp from pter
Size:
15,438 bases
Orientation:
Plus strand

Genomic View for ZNF233 Gene

Genes around ZNF233 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF233 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF233 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF233 Gene

Proteins for ZNF233 Gene

  • Protein details for ZNF233 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NK53-ZN233_HUMAN
    Recommended name:
    Zinc finger protein 233
    Protein Accession:
    A6NK53
    Secondary Accessions:
    • B2RN78
    • B2RN79
    • Q86WL8

    Protein attributes for ZNF233 Gene

    Size:
    670 amino acids
    Molecular mass:
    76861 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF233 Gene

Post-translational modifications for ZNF233 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF233 Gene

Domains & Families for ZNF233 Gene

Gene Families for ZNF233 Gene

Protein Domains for ZNF233 Gene

Suggested Antigen Peptide Sequences for ZNF233 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NK53

UniProtKB/Swiss-Prot:

ZN233_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF233: view

Function for ZNF233 Gene

Molecular function for ZNF233 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF233: view
genes like me logo Genes that share phenotypes with ZNF233: view

Animal Model Products

miRNA for ZNF233 Gene

miRTarBase miRNAs that target ZNF233

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF233 Gene

Localization for ZNF233 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF233 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF233 Gene COMPARTMENTS Subcellular localization image for ZNF233 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF233: view

Pathways & Interactions for ZNF233 Gene

SuperPathways for ZNF233 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF233: view

Pathways by source for ZNF233 Gene

2 Reactome pathways for ZNF233 Gene

Gene Ontology (GO) - Biological Process for ZNF233 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF233: view

No data available for SIGNOR curated interactions for ZNF233 Gene

Transcripts for ZNF233 Gene

Unigene Clusters for ZNF233 Gene

Zinc finger protein 233:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF233 Gene

No ASD Table

Relevant External Links for ZNF233 Gene

GeneLoc Exon Structure for
ZNF233
ECgene alternative splicing isoforms for
ZNF233

Expression for ZNF233 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF233 Gene

Protein differential expression in normal tissues from HIPED for ZNF233 Gene

This gene is overexpressed in Plasma (68.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF233 Gene



Protein tissue co-expression partners for ZNF233 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF233 Gene:

ZNF233

SOURCE GeneReport for Unigene cluster for ZNF233 Gene:

Hs.466891
genes like me logo Genes that share expression patterns with ZNF233: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF233 Gene

Orthologs for ZNF233 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF233 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF233 35
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 41 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp111 35
  • 41 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 35
  • 41 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 44 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii zgc:162972 35
  • 35 (a)
ManyToMany
fruit fly
(Drosophila melanogaster)
Insecta CG4360 35
  • 23 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea tag-146 35
  • 19 (a)
ManyToMany
C27A12.2 35
  • 16 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 36 (a)
ManyToMany
Species where no ortholog for ZNF233 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF233 Gene

ENSEMBL:
Gene Tree for ZNF233 (if available)
TreeFam:
Gene Tree for ZNF233 (if available)

Paralogs for ZNF233 Gene

(499) SIMAP similar genes for ZNF233 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF233: view

Variants for ZNF233 Gene

Sequence variations from dbSNP and Humsavar for ZNF233 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10418754 -- 44,262,182(+) CTAGG(C/T)GCTTG intron-variant
rs10542946 -- 44,268,148(+) CAAAA(-/ATAC)ATACA intron-variant, utr-variant-3-prime
rs10585082 -- 44,264,780(+) ATGTT(-/GTT)ACTAG intron-variant
rs10775542 -- 44,275,493(+) TTGGG(A/T)GCTAG downstream-variant-500B
rs111412627 -- 44,272,602(+) TGGTG(C/G)CAGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF233 Gene

Variant ID Type Subtype PubMed ID
nsv521923 CNV loss 19592680

Variation tolerance for ZNF233 Gene

Residual Variation Intolerance Score: 88.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 13.76; 95.80% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF233 Gene

Human Gene Mutation Database (HGMD)
ZNF233
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF233

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF233 Gene

Disorders for ZNF233 Gene

Relevant External Links for ZNF233

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF233

No disorders were found for ZNF233 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF233 Gene

Publications for ZNF233 Gene

  1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia. (PMID: 21078624) Kahle J.J. … Zoghbi H.Y. (Hum. Mol. Genet. 2011) 3 64
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for ZNF233 Gene

Sources for ZNF233 Gene

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