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Aliases for ZNF232 Gene

Aliases for ZNF232 Gene

  • Zinc Finger Protein 232 2 3 5
  • Zinc Finger And SCAN Domain-Containing Protein 11 3 4
  • ZSCAN11 3 4

External Ids for ZNF232 Gene

Previous GeneCards Identifiers for ZNF232 Gene

  • GC17M005428
  • GC17M004953
  • GC17M005209
  • GC17M004949
  • GC17M004899
  • GC17M005008

Summaries for ZNF232 Gene

GeneCards Summary for ZNF232 Gene

ZNF232 (Zinc Finger Protein 232) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZSCAN16.

UniProtKB/Swiss-Prot for ZNF232 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF232 Gene

Genomics for ZNF232 Gene

Regulatory Elements for ZNF232 Gene

Promoters for ZNF232 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF232 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF232 Gene

Chromosome:
17
Start:
5,105,541 bp from pter
End:
5,123,116 bp from pter
Size:
17,576 bases
Orientation:
Minus strand

Genomic View for ZNF232 Gene

Genes around ZNF232 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF232 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF232 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF232 Gene

Proteins for ZNF232 Gene

  • Protein details for ZNF232 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UNY5-ZN232_HUMAN
    Recommended name:
    Zinc finger protein 232
    Protein Accession:
    Q9UNY5

    Protein attributes for ZNF232 Gene

    Size:
    417 amino acids
    Molecular mass:
    47688 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH16039.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF232 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF232 Gene

Proteomics data for ZNF232 Gene at MOPED

Post-translational modifications for ZNF232 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZNF232 Gene

Domains & Families for ZNF232 Gene

Gene Families for ZNF232 Gene

Suggested Antigen Peptide Sequences for ZNF232 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UNY5

UniProtKB/Swiss-Prot:

ZN232_HUMAN :
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 5 C2H2-type zinc fingers.
Domain:
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF232: view

Function for ZNF232 Gene

Molecular function for ZNF232 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with ZNF232: view
genes like me logo Genes that share phenotypes with ZNF232: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF232 Gene

Localization for ZNF232 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF232 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF232 Gene COMPARTMENTS Subcellular localization image for ZNF232 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF232 Gene

Pathways & Interactions for ZNF232 Gene

SuperPathways for ZNF232 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF232 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ZNF232 Gene

Drugs & Compounds for ZNF232 Gene

No Compound Related Data Available

Transcripts for ZNF232 Gene

Unigene Clusters for ZNF232 Gene

Zinc finger protein 232:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF232 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c
SP1: - - -
SP2: - - - -
SP3: - - -
SP4:
SP5: -
SP6: -
SP7:
SP8: - -
SP9: -

Relevant External Links for ZNF232 Gene

GeneLoc Exon Structure for
ZNF232
ECgene alternative splicing isoforms for
ZNF232

Expression for ZNF232 Gene

mRNA expression in normal human tissues for ZNF232 Gene

Protein differential expression in normal tissues from HIPED for ZNF232 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF232 Gene



SOURCE GeneReport for Unigene cluster for ZNF232 Gene Hs.279914

mRNA Expression by UniProt/SwissProt for ZNF232 Gene

Q9UNY5-ZN232_HUMAN
Tissue specificity: Ubiquitous. Higher expression seen in the liver, testis and ovary.
genes like me logo Genes that share expression patterns with ZNF232: view

Protein tissue co-expression partners for ZNF232 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF232 Gene

Orthologs for ZNF232 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF232 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF232 35
  • 99.62 (n)
  • 99.55 (a)
ZNF232 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 29 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 36 (a)
ManyToMany
Species with no ortholog for ZNF232:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF232 Gene

ENSEMBL:
Gene Tree for ZNF232 (if available)
TreeFam:
Gene Tree for ZNF232 (if available)

Paralogs for ZNF232 Gene

(502) SIMAP similar genes for ZNF232 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF232 Gene

genes like me logo Genes that share paralogs with ZNF232: view

Variants for ZNF232 Gene

Sequence variations from dbSNP and Humsavar for ZNF232 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
VAR_035573 A colorectal cancer sample

Structural Variations from Database of Genomic Variants (DGV) for ZNF232 Gene

Variant ID Type Subtype PubMed ID
nsv907620 CNV Loss 21882294
nsv907623 CNV Loss 21882294
nsv907624 CNV Loss 21882294
esv25210 CNV Gain 19812545

Variation tolerance for ZNF232 Gene

Residual Variation Intolerance Score: 15.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.07; 37.96% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF232 Gene

HapMap Linkage Disequilibrium report
ZNF232

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF232 Gene

Disorders for ZNF232 Gene

Relevant External Links for ZNF232

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF232

No disorders were found for ZNF232 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF232 Gene

Publications for ZNF232 Gene

  1. ZNF232: structure and expression analysis of a novel human C(2)H(2) zinc finger gene, member of the SCAN/LeR domain subfamily. (PMID: 11311944) Mavrogiannis L.A. … Moschonas N.K. (Biochim. Biophys. Acta 2001) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  5. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3

Products for ZNF232 Gene

Sources for ZNF232 Gene

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