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Aliases for ZNF232 Gene

Aliases for ZNF232 Gene

  • Zinc Finger Protein 232 2 3 5
  • Zinc Finger And SCAN Domain-Containing Protein 11 3 4
  • ZSCAN11 3 4

External Ids for ZNF232 Gene

Previous GeneCards Identifiers for ZNF232 Gene

  • GC17M005428
  • GC17M004953
  • GC17M005209
  • GC17M004949
  • GC17M004899
  • GC17M005008

Summaries for ZNF232 Gene

GeneCards Summary for ZNF232 Gene

ZNF232 (Zinc Finger Protein 232) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF397.

UniProtKB/Swiss-Prot for ZNF232 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF232 Gene

Genomics for ZNF232 Gene

Regulatory Elements for ZNF232 Gene

Enhancers for ZNF232 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G004965 1.4 ENCODE dbSUPER 35.6 +154.5 154500 5.4 CREB3L1 AGO1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 SPAG7 ZNF232 INCA1 CHRNE LOC100130950 LOC101927979 KIF1C DHX33 CAMTA2 RNF167
GH17G004262 1.1 ENCODE 31.4 +859.4 859419 2.3 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF143 ZNF207 ZNF232 LOC101927979 LOC100130950 ZNF594 LOC105371492 ENSG00000263164 ENSG00000235085 CYB5D2 ANKFY1 RYKP1
GH17G004407 0.8 ENCODE 42.4 +715.1 715088 0.9 PKNOX1 FOXA2 ZFP64 ZNF354C FOS CREM ZNF202 ZNF680 ZNF426 REST LOC101927979 ZNF232 ZNF594 LOC100130950 LOC105371492 ENSG00000263220 INCA1 CYB5D2 SPNS3 GC17P004368
GH17G004502 1.4 Ensembl ENCODE dbSUPER 23.5 +618.5 618474 4.5 HDGF PKNOX1 FOXA2 ZFP64 BMI1 TCF12 ZNF121 FOS EGR2 ZNF680 LOC101927979 ZNF594 ZNF232 LOC100130950 LOC105371492 INCA1 DHX33 MYBBP1A PIR54894 GC17M004505
GH17G004359 1.1 dbSUPER 29 +763.1 763146 1.9 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 SP3 ZNF232 LOC100130950 ZNF594 ENSG00000263164 ENSG00000262678 LOC101927979 RN7SL774P GC17M004334
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF232 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF232 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000090587 116 801 PKNOX1 POLR2A SCRT2 FOS EZH2 FOXA1

Genomic Location for ZNF232 Gene

Chromosome:
17
Start:
5,105,541 bp from pter
End:
5,123,116 bp from pter
Size:
17,576 bases
Orientation:
Minus strand

Genomic View for ZNF232 Gene

Genes around ZNF232 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF232 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF232 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF232 Gene

Proteins for ZNF232 Gene

  • Protein details for ZNF232 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UNY5-ZN232_HUMAN
    Recommended name:
    Zinc finger protein 232
    Protein Accession:
    Q9UNY5

    Protein attributes for ZNF232 Gene

    Size:
    417 amino acids
    Molecular mass:
    47688 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH16039.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF232 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF232 Gene

Post-translational modifications for ZNF232 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF232 Gene

Domains & Families for ZNF232 Gene

Gene Families for ZNF232 Gene

Protein Domains for ZNF232 Gene

Suggested Antigen Peptide Sequences for ZNF232 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UNY5

UniProtKB/Swiss-Prot:

ZN232_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF232: view

Function for ZNF232 Gene

Molecular function for ZNF232 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF232: view
genes like me logo Genes that share phenotypes with ZNF232: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF232 Gene

Localization for ZNF232 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF232 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF232 gene
Compartment Confidence
nucleus 5
cytosol 4

Gene Ontology (GO) - Cellular Components for ZNF232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005829 cytosol IDA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with ZNF232: view

Pathways & Interactions for ZNF232 Gene

SuperPathways for ZNF232 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF232 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF232: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF232 Gene

Transcripts for ZNF232 Gene

Unigene Clusters for ZNF232 Gene

Zinc finger protein 232:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF232 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c
SP1: - - -
SP2: - - - -
SP3: - - -
SP4:
SP5: -
SP6: -
SP7:
SP8: - -
SP9: -

Relevant External Links for ZNF232 Gene

GeneLoc Exon Structure for
ZNF232
ECgene alternative splicing isoforms for
ZNF232

Expression for ZNF232 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF232 Gene

Protein differential expression in normal tissues from HIPED for ZNF232 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF232 Gene



Protein tissue co-expression partners for ZNF232 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF232 Gene:

ZNF232

SOURCE GeneReport for Unigene cluster for ZNF232 Gene:

Hs.279914

mRNA Expression by UniProt/SwissProt for ZNF232 Gene:

Q9UNY5-ZN232_HUMAN
Tissue specificity: Ubiquitous. Higher expression seen in the liver, testis and ovary.

Evidence on tissue expression from TISSUES for ZNF232 Gene

  • Eye(4)
genes like me logo Genes that share expression patterns with ZNF232: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF232 Gene

Orthologs for ZNF232 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF232 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF232 34 35
  • 99.62 (n)
dog
(Canis familiaris)
Mammalia -- 35
  • 51 (a)
OneToMany
-- 35
  • 29 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 36 (a)
ManyToMany
Species where no ortholog for ZNF232 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF232 Gene

ENSEMBL:
Gene Tree for ZNF232 (if available)
TreeFam:
Gene Tree for ZNF232 (if available)

Paralogs for ZNF232 Gene

(502) SIMAP similar genes for ZNF232 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF232: view

Variants for ZNF232 Gene

Sequence variations from dbSNP and Humsavar for ZNF232 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
VAR_035573 A colorectal cancer sample
rs1000102971 -- 5,115,688(+) AAATT(C/T)CGTTT intron-variant, upstream-variant-2KB
rs1000107274 -- 5,120,735(+) AGGAC(A/C)AGAAA intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000164948 -- 5,118,270(+) GCTCA(A/G)CCTCT intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000177183 -- 5,114,524(+) TCTCT(A/G)ATGTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF232 Gene

Variant ID Type Subtype PubMed ID
esv25210 CNV gain 19812545
nsv574273 CNV gain 21841781

Variation tolerance for ZNF232 Gene

Residual Variation Intolerance Score: 15.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.07; 37.96% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF232 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF232

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF232 Gene

Disorders for ZNF232 Gene

Relevant External Links for ZNF232

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF232

No disorders were found for ZNF232 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF232 Gene

Publications for ZNF232 Gene

  1. ZNF232: structure and expression analysis of a novel human C(2)H(2) zinc finger gene, member of the SCAN/LeR domain subfamily. (PMID: 11311944) Mavrogiannis L.A. … Moschonas N.K. (Biochim. Biophys. Acta 2001) 2 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3 64

Products for ZNF232 Gene

Sources for ZNF232 Gene

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