ZNF232 Gene
protein-coding GIFtS: 46
GCID: GC17M005008
|
|
zinc finger protein 232
| |
Aliases
for ZNF232 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 2321 2 | | ZSCAN111 2 3 | | Zinc Finger And SCAN Domain-Containing Protein 112 3 |
Export aliases for ZNF232 gene to outside databasesPrevious GC identifers: GC17M005428 GC17M004953 GC17M005209 GC17M004949 GC17M004899 |
Summaries
for ZNF232 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN232_HUMAN, Q9UNY5Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF232 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF232 gene promoter:
GR PPAR-alpha AP-2alpha isoform 3 GR-beta AP-2alpha isoform 2 GR-alpha AP-2alpha YY1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF232
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF232 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p13.2 Ensembl cytogenetic band: 17p13.2 HGNC cytogenetic band: 17p13.2ZNF232 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M005008: view genomic region
(about GC identifiers)
Start:
|
5,008,836 bp from pter |
End:
|
5,026,411 bp from pter |
Size:
|
17,576 bases |
Orientation:
|
minus strand |
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Proteins
for ZNF232 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN232_HUMAN, Q9UNY5 (See
protein sequence)Recommended Name: Zinc finger protein 232 Size: 417 amino acids; 47688 Da
Subcellular location: Nucleus
Sequence caution: Sequence=AAH16039.2; Type=Erroneous initiation;Alternative splicing: 2 isoforms: Q9UNY5-1 Q9UNY5-2 Explore the universe of human proteins at neXtProt for ZNF232: NX_Q9UNY5
ZNF232 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055334.2
ENSEMBL proteins: ENSP00000461305 ENSP00000250076 ENSP00000461267 ENSP00000458387 ENSP00000458589 ENSP00000416430
Human Recombinant Protein Products for ZNF232:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF232 for ontologies About GeneDecksing
ZNF232 Antibody Products:
Assay Products for ZNF232: |
Protein
Domains /
Families
for ZNF232 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF232 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UNY5ProtoNet protein and cluster: Q9UNY5 1 Blocks protein family: IPB003309 Transcriptional regulator SCAN
UniProtKB/Swiss-Prot: ZN232_HUMAN, Q9UNY5Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 5 C2H2-type zinc fingersSimilarity: Contains 1 SCAN box domain |
Function
for ZNF232 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN232_HUMAN, Q9UNY5Function: May be involved in transcriptional regulation Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
-- | -- | | GO:0003677 | DNA binding |
IEA | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
ZNF232 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF232
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF232
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF232 (NM_014519) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF232 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF232 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF232 |
|
Pathways & Interactions
for ZNF232 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF232
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/9 Interacting proteins for ZNF232 (Q9UNY52, 3 ENSP000002500764) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0016032 | viral reproduction |
IEA | -- |
ZNF232 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF232 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF232
Search CenterWatch for drugs/clinical trials and news about ZNF232 / ZN232
|
Transcripts
for ZNF232 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF232 gene: NM_014519.2 Unigene Cluster for ZNF232: Zinc finger protein 232 Hs.279914 [show with all ESTs]Unigene Representative Sequence: NM_0145199 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000575898 ENST00000250076(uc002gar.1 uc002gat.3) ENST00000574735
ENST00000573015 ENST00000570486(uc010vsv.1) ENST00000572468 ENST00000575538
ENST00000571076 ENST00000416429
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF232
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF232
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF232 (NM_014519) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF232 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF232 |
Additional cDNA sequence: AK057506.1 AK225622.1 AK297835.1 AK298190.1 AK316369.1 BC016039.1 Y15067.1 11 DOTS entries: DT.110386 DT.100020080 DT.100017498 DT.95370872 DT.40295634 DT.110387 DT.97775979 DT.100814299 DT.95312150 DT.86852103 DT.92422320 24/82 AceView cDNA sequences (see all 82): M77876 T87696 BC016039 Y15067 AI565571 NM_014519 AI400917 BE138901 AW469985 F03577 BE513403 AA974380 AA315122 AV718209 BQ184519 BQ641476 Z44500 AK057506 CA415387 BQ071478 CA307358 BQ187614 AI972858 CA307374
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF232 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8 | ^ | 9a | · | 9b | · | 9c |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | - | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF232
|
Expression
for ZNF232 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF232 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAGAAAAGA
About this image
See ZNF232 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF232
SOURCE GeneReport for Unigene cluster: Hs.279914
UniProtKB/Swiss-Prot: ZN232_HUMAN, Q9UNY5Tissue specificity: Ubiquitous. Higher expression seen in the liver, testis and ovary
SABiosciences Custom PCR Arrays for ZNF232
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF232
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF232 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF232 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF232 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF232 |
Orthologs
for ZNF232 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF232 (if available)
TreeFam Gene Tree for ZNF232 (if available) |
Paralogs
for ZNF232 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF232 gene
- ZNF4962 ZNF4492 ZNF4462 ZSCAN92 ZKSCAN12 ZNF3972 ZNF5002 ZNF2132
- ZSCAN302 ZNF2022 ZNF2632 ZKSCAN42 ZNF1742 ZSCAN252 ZNF3962 ZSCAN122
- ZNF3942 ZSCAN212 ZSCAN232 ZNF1652 ZSCAN162 ZKSCAN82 ZSCAN312 ZSCAN222
- ZKSCAN32 ZNF242 ZNF182
18/502 SIMAP similar genes for ZNF232 using alignment to 4 protein entries: ZN232_HUMAN (see all proteins)
(see all similar genes):ZNF78L1 kr-znf3 ZNF107 ZNF383 ZNF519 ZNF682
ZFP90 ZNF28 ZNF283 ZNF347 ZNF429 ZNF790
ZNF813 ZNF93 ZNF83 DKFZp686L0787 LOC100128510 ZNF132
ZNF232 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZNF232
PGOHUM00000259355 PGOHUM00000260156
|
Genomic Variants
for ZNF232 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF232 (5008836 - 5026411 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF232
1 CNV: 72779 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF232 |
|
Disorders
/ Diseases
for ZNF232 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF232 for disorders About MalaCards
ZNF232 for disorders About GeneDecksing
1 disease from the University of Copenhagen DISEASES database for ZNF232:Asperger syndrome Export disorders for ZNF232 gene to outside databases
|
Publications
for ZNF232 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF232 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF232) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- ZNF232: structure and expression analysis of a novel human C(2)H(2) zinc finger gene, member of the SCAN/LeR domain subfamily. (PubMed id 11311944)1, 2, 3 Mavrogiannis L.A.... Moschonas N.K. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
- The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (1994)
|
External Searches for ZNF232 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF232 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF232 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF232 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF232 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF232 gene:
Search GeneIP for patents involving ZNF232
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF232 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF232 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF232 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF232 | | | OriGene Protein Over-expression Lysate for ZNF232 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF232 | | OriGene 3'-UTR Clone for ZNF232 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF232 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF232 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| |  |  |  |  | | | | |
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 | | | ZNF232 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF232 |
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