Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF230 Gene

Aliases for ZNF230 Gene

  • Zinc Finger Protein 230 2 3
  • Zinc Finger Protein FDZF2 3 4
  • FDZF2 3 4

External Ids for ZNF230 Gene

Previous GeneCards Identifiers for ZNF230 Gene

  • GC19P045152
  • GC19P044898
  • GC19P049183
  • GC19P049198
  • GC19P049181
  • GC19P044270
  • GC19P044507

Summaries for ZNF230 Gene

GeneCards Summary for ZNF230 Gene

ZNF230 (Zinc Finger Protein 230) is a Protein Coding gene. Diseases associated with ZNF230 include lung cancer. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF155.

UniProtKB/Swiss-Prot for ZNF230 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF230 Gene

Genomics for ZNF230 Gene

Genomic Location for ZNF230 Gene

44,002,925 bp from pter
44,013,926 bp from pter
11,002 bases
Plus strand

Genomic View for ZNF230 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF230 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF230 Gene

No data available for Regulatory Elements for ZNF230 Gene

Proteins for ZNF230 Gene

  • Protein details for ZNF230 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 230
    Protein Accession:
    Secondary Accessions:
    • O15322
    • Q504X7
    • Q86W84
    • Q9P1U6

    Protein attributes for ZNF230 Gene

    474 amino acids
    Molecular mass:
    54542 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF230 Gene

Proteomics data for ZNF230 Gene at MOPED

Post-translational modifications for ZNF230 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF230 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF230 Gene

Domains for ZNF230 Gene

Gene Families for ZNF230 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF230 Gene

Suggested Antigen Peptide Sequences for ZNF230 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9UIE0
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF230: view

Function for ZNF230 Gene

Molecular function for ZNF230 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF230 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF230: view

miRNA for ZNF230 Gene

miRTarBase miRNAs that target ZNF230

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF230 Gene

Localization for ZNF230 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF230 Gene

Gene Ontology (GO) - Cellular Components for ZNF230 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF230: view

No data available for Subcellular locations from COMPARTMENTS for ZNF230 Gene

Pathways for ZNF230 Gene

SuperPathways for ZNF230 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF230: view

Pathways by source for ZNF230 Gene

2 Reactome pathways for ZNF230 Gene

Gene Ontology (GO) - Biological Process for ZNF230 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF230: view

Transcripts for ZNF230 Gene

Unigene Clusters for ZNF230 Gene

Zinc finger protein 230:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF230 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7
SP1: -
SP3: -

Relevant External Links for ZNF230 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF230 Gene

mRNA expression in normal human tissues for ZNF230 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF230 Gene

This gene is overexpressed in Whole Blood (4.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF230 Gene

SOURCE GeneReport for Unigene cluster for ZNF230 Gene Hs.193583

genes like me logo Genes that share expressions with ZNF230: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF230 Gene

Orthologs for ZNF230 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF230 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF230 35
  • 99.37 (n)
  • 98.95 (a)
ZNF230 36
  • 99 (a)
Species with no ortholog for ZNF230:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF230 Gene

Gene Tree for ZNF230 (if available)
Gene Tree for ZNF230 (if available)

Paralogs for ZNF230 Gene

Selected SIMAP similar genes for ZNF230 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF230: view

Variants for ZNF230 Gene

Sequence variations from dbSNP and Humsavar for ZNF230 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs12753 - 44,011,362(+) GGAGA(A/C)CACAA missense, reference
rs382197 -- 44,004,945(-) agaga(C/T)ggggt intron-variant
rs427608 -- 44,008,472(-) ATGAG(C/G)AATTC intron-variant
rs430107 -- 44,006,546(-) actcc(A/G)cttta intron-variant
rs454904 -- 44,007,437(+) ATGTC(A/G)AGAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF230 Gene

Variant ID Type Subtype PubMed ID
nsv469650 CNV Gain 16826518
nsv819782 CNV Loss 19587683

Relevant External Links for ZNF230 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF230 Gene

Disorders for ZNF230 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for ZNF230 Gene including...

Search for ZNF230 Gene in MalaCards »

Relevant External Links for ZNF230

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with ZNF230: view

No data available for UniProtKB/Swiss-Prot for ZNF230 Gene

Publications for ZNF230 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Screening for ZNF230 gene mutation and analysis of its correlation with azoospermia. (PMID: 15952109) Dong J.T. … Peng Y. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2005) 3 48
  4. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PMID: 18676680) Hosgood H.D. … Lan Q. (Carcinogenesis 2008) 3 48
  5. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M. … Lan Q. (Environ. Mol. Mutagen. 2009) 3 48

Products for ZNF230 Gene

Sources for ZNF230 Gene

Back to Top