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Aliases for ZNF230 Gene

Aliases for ZNF230 Gene

  • Zinc Finger Protein 230 2 3 5
  • Zinc Finger Protein FDZF2 3 4
  • FDZF2 3 4

External Ids for ZNF230 Gene

Previous GeneCards Identifiers for ZNF230 Gene

  • GC19P045152
  • GC19P044898
  • GC19P049183
  • GC19P049198
  • GC19P049181
  • GC19P044270
  • GC19P044507

Summaries for ZNF230 Gene

GeneCards Summary for ZNF230 Gene

ZNF230 (Zinc Finger Protein 230) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF229.

UniProtKB/Swiss-Prot for ZNF230 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF230 Gene

Genomics for ZNF230 Gene

Regulatory Elements for ZNF230 Gene

Enhancers for ZNF230 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF230 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF230 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF230 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF230 Gene

44,002,925 bp from pter
44,013,926 bp from pter
11,002 bases
Plus strand

Genomic View for ZNF230 Gene

Genes around ZNF230 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF230 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF230 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF230 Gene

Proteins for ZNF230 Gene

  • Protein details for ZNF230 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 230
    Protein Accession:
    Secondary Accessions:
    • O15322
    • Q504X7
    • Q86W84
    • Q9P1U6

    Protein attributes for ZNF230 Gene

    474 amino acids
    Molecular mass:
    54542 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF230 Gene

Proteomics data for ZNF230 Gene at MOPED

Post-translational modifications for ZNF230 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF230 Gene

No data available for DME Specific Peptides for ZNF230 Gene

Domains & Families for ZNF230 Gene

Gene Families for ZNF230 Gene

Protein Domains for ZNF230 Gene

Suggested Antigen Peptide Sequences for ZNF230 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF230: view

Function for ZNF230 Gene

Molecular function for ZNF230 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF230: view

Animal Model Products

CRISPR Products

miRNA for ZNF230 Gene

miRTarBase miRNAs that target ZNF230

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF230 Gene

Localization for ZNF230 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF230 Gene

Subcellular locations from

Jensen Localization Image for ZNF230 Gene COMPARTMENTS Subcellular localization image for ZNF230 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF230 Gene

Pathways & Interactions for ZNF230 Gene

SuperPathways for ZNF230 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF230: view

Pathways by source for ZNF230 Gene

2 Reactome pathways for ZNF230 Gene

Gene Ontology (GO) - Biological Process for ZNF230 Gene


No data available for SIGNOR curated interactions for ZNF230 Gene

Drugs & Compounds for ZNF230 Gene

No Compound Related Data Available

Transcripts for ZNF230 Gene

Unigene Clusters for ZNF230 Gene

Zinc finger protein 230:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF230 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7
SP1: -
SP3: -

Relevant External Links for ZNF230 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF230 Gene

mRNA expression in normal human tissues for ZNF230 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF230 Gene

This gene is overexpressed in Whole Blood (x4.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF230 Gene

SOURCE GeneReport for Unigene cluster for ZNF230 Gene Hs.193583

genes like me logo Genes that share expression patterns with ZNF230: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF230 Gene

Orthologs for ZNF230 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF230 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF230 35
  • 99.37 (n)
  • 98.95 (a)
ZNF230 36
  • 99 (a)
Species with no ortholog for ZNF230:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF230 Gene

Gene Tree for ZNF230 (if available)
Gene Tree for ZNF230 (if available)

Paralogs for ZNF230 Gene

(459) SIMAP similar genes for ZNF230 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF230: view

Variants for ZNF230 Gene

Sequence variations from dbSNP and Humsavar for ZNF230 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs12753 - 44,011,362(+) GGAGA(A/C)CACAA reference, missense
rs1060877 - 44,010,968(+) CAAAT(C/G)TGAGG reference, missense
rs6413542 - 44,011,340(+) GTCTT(A/T)CTGTA reference, missense
rs7256345 -- 44,006,753(+) TCTTA(G/T)GATGT intron-variant
rs13345807 -- 44,010,723(+) GAGCA(A/G)TGTGG reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZNF230 Gene

Variant ID Type Subtype PubMed ID
nsv469650 CNV Gain 16826518
nsv819782 CNV Loss 19587683

Variation tolerance for ZNF230 Gene

Residual Variation Intolerance Score: 88.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.86; 67.31% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF230 Gene

Disorders for ZNF230 Gene

Relevant External Links for ZNF230

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF230 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF230 Gene

Publications for ZNF230 Gene

  1. Genetic susceptibility to distinct bladder cancer subphenotypes. (PMID: 19692168) Guey L.T. … Malats N. (Eur. Urol. 2010) 3 48 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Spermatogenesis-related ring finger gene ZNF230 promoter: identification and functional analysis. (PMID: 18584306) Xu W. … Zhang W. (Mol. Biol. Rep. 2009) 3
  5. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PMID: 19170196) Shen M. … Lan Q. (Environ. Mol. Mutagen. 2009) 3

Products for ZNF230 Gene

Sources for ZNF230 Gene