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Aliases for ZNF23 Gene

Aliases for ZNF23 Gene

  • Zinc Finger Protein 23 2 3
  • Zinc Finger Protein 359 2 3 4
  • KOX16 3 4 6
  • Zinc Finger Protein 612 3 4
  • ZNF359 3 4
  • ZNF612 3 4
  • Kruppel-Like Zinc Finger Factor X31 3
  • Zinc Finger Protein 23 (KOX 16) 3
  • Zinc Finger Protein KOX16 4
  • Zinc Finger Protein 32 3
  • Zfp612 3

External Ids for ZNF23 Gene

Previous HGNC Symbols for ZNF23 Gene

  • ZNF359

Previous GeneCards Identifiers for ZNF23 Gene

  • GC16U990062
  • GC16M072204
  • GC16M071216
  • GC16M071257
  • GC16M070039
  • GC16M071481
  • GC16M057249

Summaries for ZNF23 Gene

GeneCards Summary for ZNF23 Gene

ZNF23 (Zinc Finger Protein 23) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF23 Gene

  • May be involved in transcriptional regulation. May have a role in embryonic development

Gene Wiki entry for ZNF23 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF23 Gene

Genomics for ZNF23 Gene

Regulatory Elements for ZNF23 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF23 Gene

Start:
71,447,597 bp from pter
End:
71,463,095 bp from pter
Size:
15,499 bases
Orientation:
Minus strand

Genomic View for ZNF23 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF23 Gene

Proteins for ZNF23 Gene

  • Protein details for ZNF23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17027-ZNF23_HUMAN
    Recommended name:
    Zinc finger protein 23
    Protein Accession:
    P17027
    Secondary Accessions:
    • Q8NDP5
    • Q96IT3
    • Q9UG42

    Protein attributes for ZNF23 Gene

    Size:
    643 amino acids
    Molecular mass:
    73059 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF23 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF23 Gene

Proteomics data for ZNF23 Gene at MOPED

Post-translational modifications for ZNF23 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF23 Gene

No data available for DME Specific Peptides for ZNF23 Gene

Domains for ZNF23 Gene

Gene Families for ZNF23 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF23 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17027

UniProtKB/Swiss-Prot:

ZNF23_HUMAN :
  • P17027
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF23: view

Function for ZNF23 Gene

Molecular function for ZNF23 Gene

GENATLAS Biochemistry: zinc finger protein 23 (KOX16) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation. May have a role in embryonic development

Gene Ontology (GO) - Molecular Function for ZNF23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF23: view

Phenotypes for ZNF23 Gene

GenomeRNAi human phenotypes for ZNF23:
genes like me logo Genes that share phenotypes with ZNF23: view

Animal Model Products

CRISPR Products

miRNA for ZNF23 Gene

miRTarBase miRNAs that target ZNF23

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF23

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF23 Gene

Localization for ZNF23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF23 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF23 Gene COMPARTMENTS Subcellular localization image for ZNF23 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for ZNF23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF23: view

Pathways for ZNF23 Gene

SuperPathways for ZNF23 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF23: view

Pathways by source for ZNF23 Gene

2 Reactome pathways for ZNF23 Gene

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for ZNF23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF23: view

Transcripts for ZNF23 Gene

Unigene Clusters for ZNF23 Gene

Zinc finger protein 23:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF23

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF23 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9a · 9b · 9c · 9d
SP1: - - - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - - - - - -
SP5: - - - - - - -
SP6: - - - - - -
SP7: - - - - -
SP8:
SP9: - - - -
SP10: - -
SP11: -

Relevant External Links for ZNF23 Gene

GeneLoc Exon Structure for
ZNF23
ECgene alternative splicing isoforms for
ZNF23

Expression for ZNF23 Gene

mRNA expression in normal human tissues for ZNF23 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF23 Gene

SOURCE GeneReport for Unigene cluster for ZNF23 Gene Hs.656643

genes like me logo Genes that share expressions with ZNF23: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF23 Gene

Orthologs for ZNF23 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF23 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF23 35
  • 99.64 (n)
  • 99.07 (a)
ZNF23 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF19 36
  • 54 (a)
OneToOne
ZNF23 35
  • 88.85 (n)
  • 85.85 (a)
dog
(Canis familiaris)
Mammalia ZNF23 35
  • 89.74 (n)
  • 89.06 (a)
ZNF23 36
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp612 35
  • 79.65 (n)
  • 77.27 (a)
Zfp612 16
Zfp612 36
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 55 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp612 35
  • 81.88 (n)
  • 77.58 (a)
Species with no ortholog for ZNF23:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF23 Gene

ENSEMBL:
Gene Tree for ZNF23 (if available)
TreeFam:
Gene Tree for ZNF23 (if available)

Paralogs for ZNF23 Gene

Selected SIMAP similar genes for ZNF23 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF23: view

Variants for ZNF23 Gene

Sequence variations from dbSNP and Humsavar for ZNF23 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs730470 -- 71,450,028(-) TCCCA(A/C/T)CTTAT intron-variant
rs919372 -- 71,462,177(+) CAGGG(C/G)ACGGC utr-variant-5-prime
rs1045797 -- 71,448,357(-) ACAGG(A/G)GAGAA reference, synonymous-codon
rs1609868 -- 71,456,390(-) ATGTA(C/G)AGAAG intron-variant
rs1609869 -- 71,456,313(-) AGGGA(G/T)TGGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF23 Gene

Variant ID Type Subtype PubMed ID
nsv7285 OTHER Inversion 18451855

Relevant External Links for ZNF23 Gene

HapMap Linkage Disequilibrium report
ZNF23

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF23 Gene

Disorders for ZNF23 Gene

(1) University of Copenhagen DISEASES for ZNF23 Gene

Relevant External Links for ZNF23

Genetic Association Database (GAD)
ZNF23
genes like me logo Genes that share disorders with ZNF23: view

No data available for UniProtKB/Swiss-Prot for ZNF23 Gene

Publications for ZNF23 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24. (PMID: 8500793) Cannizzaro L.A. … Thiesen H.J. (Hum. Genet. 1993) 3 23
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  4. Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development. (PMID: 12127974) Zhou L. … Wu X. (Biochem. Biophys. Res. Commun. 2002) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF23 Gene

Sources for ZNF23 Gene

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