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Aliases for ZNF23 Gene

Aliases for ZNF23 Gene

  • Zinc Finger Protein 23 2 3 5
  • Zinc Finger Protein 359 2 3 4
  • Zinc Finger Protein 612 3 4
  • ZNF359 3 4
  • ZNF612 3 4
  • KOX16 3 4
  • Kruppel-Like Zinc Finger Factor X31 3
  • Zinc Finger Protein 23 (KOX 16) 3
  • Zinc Finger Protein KOX16 4
  • Zinc Finger Protein 32 3
  • Zfp612 3

External Ids for ZNF23 Gene

Previous HGNC Symbols for ZNF23 Gene

  • ZNF359

Previous GeneCards Identifiers for ZNF23 Gene

  • GC16U990062
  • GC16M072204
  • GC16M071216
  • GC16M071257
  • GC16M070039
  • GC16M071481
  • GC16M057249
  • GC16M071449
  • GC16M071450

Summaries for ZNF23 Gene

GeneCards Summary for ZNF23 Gene

ZNF23 (Zinc Finger Protein 23) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF70.

UniProtKB/Swiss-Prot for ZNF23 Gene

  • May be involved in transcriptional regulation. May have a role in embryonic development.

Gene Wiki entry for ZNF23 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF23 Gene

Genomics for ZNF23 Gene

Regulatory Elements for ZNF23 Gene

Enhancers for ZNF23 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF23 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF23 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF23 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF23 Gene

71,447,597 bp from pter
71,463,095 bp from pter
15,499 bases
Minus strand

Genomic View for ZNF23 Gene

Genes around ZNF23 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF23 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF23 Gene

Proteins for ZNF23 Gene

  • Protein details for ZNF23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 23
    Protein Accession:
    Secondary Accessions:
    • Q8NDP5
    • Q96IT3
    • Q9UG42

    Protein attributes for ZNF23 Gene

    643 amino acids
    Molecular mass:
    73059 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF23 Gene


neXtProt entry for ZNF23 Gene

Proteomics data for ZNF23 Gene at MOPED

Post-translational modifications for ZNF23 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZNF23 Gene

Domains & Families for ZNF23 Gene

Gene Families for ZNF23 Gene

Protein Domains for ZNF23 Gene

Suggested Antigen Peptide Sequences for ZNF23 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF23: view

Function for ZNF23 Gene

Molecular function for ZNF23 Gene

GENATLAS Biochemistry:
zinc finger protein 23 (KOX16) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation. May have a role in embryonic development.
genes like me logo Genes that share phenotypes with ZNF23: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF23 Gene

Localization for ZNF23 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF23 Gene

Subcellular locations from

Jensen Localization Image for ZNF23 Gene COMPARTMENTS Subcellular localization image for ZNF23 gene
Compartment Confidence
nucleus 5
cytosol 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF23 Gene

Pathways & Interactions for ZNF23 Gene

SuperPathways for ZNF23 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF23: view

Pathways by source for ZNF23 Gene

2 Reactome pathways for ZNF23 Gene

Gene Ontology (GO) - Biological Process for ZNF23 Gene


No data available for SIGNOR curated interactions for ZNF23 Gene

Drugs & Compounds for ZNF23 Gene

No Compound Related Data Available

Transcripts for ZNF23 Gene

Unigene Clusters for ZNF23 Gene

Zinc finger protein 23:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF23 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9a · 9b · 9c · 9d
SP1: - - - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - - - - - -
SP5: - - - - - - -
SP6: - - - - - -
SP7: - - - - -
SP9: - - - -
SP10: - -
SP11: -

Relevant External Links for ZNF23 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF23 Gene

mRNA expression in normal human tissues for ZNF23 Gene

Protein differential expression in normal tissues from HIPED for ZNF23 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF23 Gene

SOURCE GeneReport for Unigene cluster for ZNF23 Gene Hs.656643

genes like me logo Genes that share expression patterns with ZNF23: view

Protein tissue co-expression partners for ZNF23 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF23 Gene

Orthologs for ZNF23 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF23 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF23 35
  • 88.85 (n)
  • 85.85 (a)
ZNF19 36
  • 54 (a)
(Canis familiaris)
Mammalia ZNF23 35
  • 89.74 (n)
  • 89.06 (a)
ZNF23 36
  • 88 (a)
(Mus musculus)
Mammalia Zfp612 35
  • 79.65 (n)
  • 77.27 (a)
Zfp612 16
Zfp612 36
  • 72 (a)
(Pan troglodytes)
Mammalia ZNF23 35
  • 99.64 (n)
  • 99.07 (a)
ZNF23 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zfp612 35
  • 81.88 (n)
  • 77.58 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 55 (a)
-- 36
  • 53 (a)
-- 36
  • 52 (a)
-- 36
  • 54 (a)
-- 36
  • 50 (a)
-- 36
  • 52 (a)
Species with no ortholog for ZNF23:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF23 Gene

Gene Tree for ZNF23 (if available)
Gene Tree for ZNF23 (if available)

Paralogs for ZNF23 Gene

(502) SIMAP similar genes for ZNF23 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF23: view

Variants for ZNF23 Gene

Sequence variations from dbSNP and Humsavar for ZNF23 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs2070832 - 71,453,303(+) CTCAC(C/T)TCCTC intron-variant, reference, missense, utr-variant-5-prime
rs3886947 -- 71,450,055(+) AACTA(C/G)TAAAA intron-variant
rs3887712 -- 71,450,104(-) TGTAT(C/T)TTGGA intron-variant
rs8063547 -- 71,447,609(+) TTTTT(C/T)AAATA utr-variant-3-prime
rs4503795 -- 71,462,496(+) ACCCA(A/G)TGCCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF23 Gene

Variant ID Type Subtype PubMed ID
nsv7285 OTHER Inversion 18451855

Variation tolerance for ZNF23 Gene

Residual Variation Intolerance Score: 43.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.36; 26.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF23 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF23 Gene

Disorders for ZNF23 Gene

Relevant External Links for ZNF23

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF23 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF23 Gene

Publications for ZNF23 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Human zinc finger gene ZNF23 (Kox16) maps to a zinc finger gene cluster on chromosome 16q22, and ZNF32 (Kox30) to chromosome region 10q23-q24. (PMID: 8500793) Cannizzaro L.A. … Thiesen H.J. (Hum. Genet. 1993) 3 23
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3

Products for ZNF23 Gene

Sources for ZNF23 Gene