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Aliases for ZNF229 Gene

Aliases for ZNF229 Gene

  • Zinc Finger Protein 229 2 3 5

External Ids for ZNF229 Gene

Previous GeneCards Identifiers for ZNF229 Gene

  • GC19M045578
  • GC19M045325
  • GC19M049609
  • GC19M049625
  • GC19M049626
  • GC19U900567
  • GC19M044930
  • GC19M041362

Summaries for ZNF229 Gene

GeneCards Summary for ZNF229 Gene

ZNF229 (Zinc Finger Protein 229) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF155.

UniProtKB/Swiss-Prot for ZNF229 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF229 Gene

Genomics for ZNF229 Gene

Regulatory Elements for ZNF229 Gene

Enhancers for ZNF229 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF229 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF229 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF229 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF229 gene promoter:

Genomic Location for ZNF229 Gene

44,417,519 bp from pter
44,448,725 bp from pter
31,207 bases
Minus strand

Genomic View for ZNF229 Gene

Genes around ZNF229 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF229 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF229 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF229 Gene

Proteins for ZNF229 Gene

  • Protein details for ZNF229 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 229
    Protein Accession:
    Secondary Accessions:
    • B2RWN3
    • Q59FV2
    • Q86WL9

    Protein attributes for ZNF229 Gene

    825 amino acids
    Molecular mass:
    93707 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAG23970.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF229 Gene


neXtProt entry for ZNF229 Gene

Proteomics data for ZNF229 Gene at MOPED

Post-translational modifications for ZNF229 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF229 Gene

No data available for DME Specific Peptides for ZNF229 Gene

Domains & Families for ZNF229 Gene

Gene Families for ZNF229 Gene

Protein Domains for ZNF229 Gene

Suggested Antigen Peptide Sequences for ZNF229 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 18 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 18 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF229: view

Function for ZNF229 Gene

Molecular function for ZNF229 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes for ZNF229 Gene

genes like me logo Genes that share phenotypes with ZNF229: view

Animal Model Products

CRISPR Products

miRNA for ZNF229 Gene

miRTarBase miRNAs that target ZNF229

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF229 Gene

Localization for ZNF229 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF229 Gene

Subcellular locations from

Jensen Localization Image for ZNF229 Gene COMPARTMENTS Subcellular localization image for ZNF229 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF229 Gene

Pathways & Interactions for ZNF229 Gene

SuperPathways for ZNF229 Gene

No Data Available

Interacting Proteins for ZNF229 Gene

Gene Ontology (GO) - Biological Process for ZNF229 Gene


No data available for Pathways by source and SIGNOR curated interactions for ZNF229 Gene

Drugs & Compounds for ZNF229 Gene

No Compound Related Data Available

Transcripts for ZNF229 Gene

mRNA/cDNA for ZNF229 Gene

(4) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF229 Gene

Zinc finger protein 229:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF229 Gene

No ASD Table

Relevant External Links for ZNF229 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF229 Gene

mRNA expression in normal human tissues for ZNF229 Gene

Protein differential expression in normal tissues from HIPED for ZNF229 Gene

This gene is overexpressed in Liver (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ZNF229 Gene

SOURCE GeneReport for Unigene cluster for ZNF229 Gene Hs.709348

genes like me logo Genes that share expression patterns with ZNF229: view

Protein tissue co-expression partners for ZNF229 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF229 Gene

Orthologs for ZNF229 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF229 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF229 35
  • 80.71 (n)
  • 77.09 (a)
(Pan troglodytes)
Mammalia ZNF229 35
  • 90.41 (n)
  • 86.99 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10274 37
  • 40 (a)
CG7963 37
  • 32 (a)
Species with no ortholog for ZNF229:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF229 Gene

Gene Tree for ZNF229 (if available)
Gene Tree for ZNF229 (if available)

Paralogs for ZNF229 Gene

(494) SIMAP similar genes for ZNF229 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF229: view

Variants for ZNF229 Gene

Sequence variations from dbSNP and Humsavar for ZNF229 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs2571174 - 44,430,314(-) GAATT(C/T)CCTGG nc-transcript-variant, reference, missense
rs12151338 - 44,429,772(+) GTTAC(A/G)TATGT nc-transcript-variant, reference, missense
rs1434579 - 44,428,797(-) AGTGC(A/G/T)GAAAG nc-transcript-variant, reference, missense
rs10409807 - 44,428,371(+) GAAGC(C/G)TTTCC nc-transcript-variant, reference, missense
rs57014690 - 44,429,531(+) CTGAG(C/T)TGTAA nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZNF229 Gene

Variant ID Type Subtype PubMed ID
nsv515911 CNV Loss 19592680
dgv3944n71 CNV Loss 21882294
esv2663330 CNV Deletion 23128226
nsv9734 CNV Gain+Loss 18304495
dgv1106e1 CNV Complex 17122850
esv2421963 CNV Deletion 20811451
nsv442465 CNV CNV 18776908
nsv817849 CNV Loss 17921354
esv6503 OTHER Inversion 19470904
esv26773 CNV Loss 19812545

Variation tolerance for ZNF229 Gene

Residual Variation Intolerance Score: 86.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.71; 91.52% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF229 Gene

Disorders for ZNF229 Gene

Relevant External Links for ZNF229

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF229 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF229 Gene

Publications for ZNF229 Gene

  1. Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2. (PMID: 20694014) Thye T. … Hill A.V. (Nat. Genet. 2010) 3 48 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3
  5. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 3

Products for ZNF229 Gene

Sources for ZNF229 Gene