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Aliases for ZNF226 Gene

Aliases for ZNF226 Gene

  • Zinc Finger Protein 226 2 3

External Ids for ZNF226 Gene

Previous GeneCards Identifiers for ZNF226 Gene

  • GC19P045314
  • GC19P045060
  • GC19P049345
  • GC19P049361
  • GC19P049355
  • GC19P044669
  • GC19P041101
  • GC19P044647

Summaries for ZNF226 Gene

GeneCards Summary for ZNF226 Gene

ZNF226 (Zinc Finger Protein 226) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF155.

UniProtKB/Swiss-Prot for ZNF226 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF226 Gene

Genomics for ZNF226 Gene

Genomic Location for ZNF226 Gene

Start:
44,165,062 bp from pter
End:
44,178,381 bp from pter
Size:
13,320 bases
Orientation:
Plus strand

Genomic View for ZNF226 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF226 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF226 Gene

No data available for Regulatory Elements for ZNF226 Gene

Proteins for ZNF226 Gene

  • Protein details for ZNF226 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NYT6-ZN226_HUMAN
    Recommended name:
    Zinc finger protein 226
    Protein Accession:
    Q9NYT6
    Secondary Accessions:
    • Q8WWE6
    • Q96TE6
    • Q9NS44

    Protein attributes for ZNF226 Gene

    Size:
    803 amino acids
    Molecular mass:
    91921 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF226 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF226 Gene

Proteomics data for ZNF226 Gene at MOPED

Post-translational modifications for ZNF226 Gene

  • Ubiquitination at Lys53, Lys585, and Lys588
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF226 Gene

Domains for ZNF226 Gene

Gene Families for ZNF226 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF226 Gene

Suggested Antigen Peptide Sequences for ZNF226 Gene

Graphical View of Domain Structure for InterPro Entry

Q9NYT6

UniProtKB/Swiss-Prot:

ZN226_HUMAN :
  • Q9NYT6
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF226: view

Function for ZNF226 Gene

Molecular function for ZNF226 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF226 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF226: view
genes like me logo Genes that share phenotypes with ZNF226: view

Animal Model Products

CRISPR Products

miRNA for ZNF226 Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF226 Gene

Localization for ZNF226 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF226 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF226 Gene COMPARTMENTS Subcellular localization image for ZNF226 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF226 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF226: view

Pathways for ZNF226 Gene

SuperPathways for ZNF226 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF226: view

Pathways by source for ZNF226 Gene

2 Reactome pathways for ZNF226 Gene

Gene Ontology (GO) - Biological Process for ZNF226 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF226: view

Transcripts for ZNF226 Gene

Unigene Clusters for ZNF226 Gene

Zinc finger protein 226:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF226

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF226
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF226 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e
SP1: - - - - - - - - -
SP2: - - - - - - - -
SP3: - - - -
SP4: - - - - - - -
SP5: - - - - - -
SP6: - - - - - - - -
SP7: -
SP8: - - - - - -
SP9: - - - - - - - - -
SP10: - - - -
SP11: - - - - -
SP12: - - -

Relevant External Links for ZNF226 Gene

GeneLoc Exon Structure for
ZNF226
ECgene alternative splicing isoforms for
ZNF226

Expression for ZNF226 Gene

mRNA expression in normal human tissues for ZNF226 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF226 Gene Hs.145956

genes like me logo Genes that share expressions with ZNF226: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF226 Gene

Orthologs for ZNF226 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF226 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF226 35
  • 99.42 (n)
  • 98.88 (a)
ZNF226 36
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 67 (a)
ManyToMany
ZNF226 35
  • 86.16 (n)
  • 83.29 (a)
mouse
(Mus musculus)
Mammalia Zfp111 35
  • 64.07 (n)
  • 59.28 (a)
Zfp111 16
Zfp61 36
  • 57 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp111 35
  • 62.48 (n)
  • 55.23 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5245 35
  • 47.77 (n)
  • 42.63 (a)
Species with no ortholog for ZNF226:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF226 Gene

ENSEMBL:
Gene Tree for ZNF226 (if available)
TreeFam:
Gene Tree for ZNF226 (if available)

Paralogs for ZNF226 Gene

Selected SIMAP similar genes for ZNF226 Gene using alignment to 11 proteins:

genes like me logo Genes that share paralogs with ZNF226: view

Variants for ZNF226 Gene

Sequence variations from dbSNP and Humsavar for ZNF226 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1105561 -- 44,165,807(-) CTCAC(A/G)TGGGG utr-variant-5-prime
rs1107064 -- 44,165,166(+) TTTCA(A/G)ACTTC utr-variant-5-prime, intron-variant
rs1881748 -- 44,165,536(+) CAAAA(A/C)GTGTA intron-variant
rs2178342 -- 44,176,336(+) CACAC(A/G)GCAGA synonymous-codon, reference
rs2232800 -- 44,164,937(+) CTCAG(C/T)TGCAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF226 Gene

Variant ID Type Subtype PubMed ID
nsv833840 CNV Gain 17160897

Relevant External Links for ZNF226 Gene

HapMap Linkage Disequilibrium report
ZNF226

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF226 Gene

Disorders for ZNF226 Gene

No disorders were found for ZNF226 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF226 Gene

Publications for ZNF226 Gene

  1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF226 Gene

Sources for ZNF226 Gene

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