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Aliases for ZNF225 Gene

Aliases for ZNF225 Gene

  • Zinc Finger Protein 225 2 3

External Ids for ZNF225 Gene

Summaries for ZNF225 Gene

GeneCards Summary for ZNF225 Gene

ZNF225 (Zinc Finger Protein 225) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF155.

UniProtKB/Swiss-Prot for ZNF225 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF225 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF225 Gene

Genomics for ZNF225 Gene

Genomic Location for ZNF225 Gene

Start:
44,112,181 bp from pter
End:
44,134,816 bp from pter
Size:
22,636 bases
Orientation:
Plus strand

Genomic View for ZNF225 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF225 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF225 Gene

No data available for Regulatory Elements for ZNF225 Gene

Proteins for ZNF225 Gene

  • Protein details for ZNF225 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UK10-ZN225_HUMAN
    Recommended name:
    Zinc finger protein 225
    Protein Accession:
    Q9UK10
    Secondary Accessions:
    • A8K8S2
    • Q53F12
    • Q9NS46
    • Q9UID8

    Protein attributes for ZNF225 Gene

    Size:
    706 amino acids
    Molecular mass:
    82471 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF225 Gene

Proteomics data for ZNF225 Gene at MOPED

Post-translational modifications for ZNF225 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF225 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF225 Gene

Domains for ZNF225 Gene

Gene Families for ZNF225 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF225 Gene

UniProtKB/Swiss-Prot:

ZN225_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q9UK10
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9UK10
Similarity:
  • Contains 18 C2H2-type zinc fingers.:
    • Q9UK10
genes like me logo Genes that share domains with ZNF225: view

Function for ZNF225 Gene

Molecular function for ZNF225 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF225 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF225: view
genes like me logo Genes that share phenotypes with ZNF225: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF225 Gene

Localization for ZNF225 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF225 Gene

Gene Ontology (GO) - Cellular Components for ZNF225 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF225: view

Pathways for ZNF225 Gene

SuperPathways for ZNF225 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF225: view

Pathways by source for ZNF225 Gene

2 Reactome pathways for ZNF225 Gene

Interacting Proteins for ZNF225 Gene

Gene Ontology (GO) - Biological Process for ZNF225 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF225: view

Transcripts for ZNF225 Gene

Unigene Clusters for ZNF225 Gene

Zinc finger protein 225:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF225 Gene

No ASD Table

Relevant External Links for ZNF225 Gene

GeneLoc Exon Structure for
ZNF225
ECgene alternative splicing isoforms for
ZNF225

Expression for ZNF225 Gene

mRNA expression in normal human tissues for ZNF225 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF225 Gene

SOURCE GeneReport for Unigene cluster for ZNF225 Gene Hs.279567

genes like me logo Genes that share expressions with ZNF225: view

Orthologs for ZNF225 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF225 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF225 36
  • 99.48 (n)
  • 99.15 (a)
ZNF225 37
  • 99 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG10669 38
  • 28 (a)
EG:95B7.7 38
  • 33 (a)
Kr 38
  • 48 (a)
CG17568 38
  • 35 (a)
Species with no ortholog for ZNF225:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF225 Gene

ENSEMBL:
Gene Tree for ZNF225 (if available)
TreeFam:
Gene Tree for ZNF225 (if available)

Paralogs for ZNF225 Gene

Selected SIMAP similar genes for ZNF225 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF225: view

Variants for ZNF225 Gene

Sequence variations from dbSNP and Humsavar for ZNF225 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2168778 -- 44,127,066(+) TTGCC(C/T)GGTTC intron-variant, upstream-variant-2KB
rs2284980 -- 44,129,321(+) AATTA(C/T)TTTCA intron-variant
rs2284981 -- 44,129,405(+) AGACA(C/G)AGTCC intron-variant
rs2300962 -- 44,116,050(+) AGAGA(C/T)GGGGT intron-variant
rs2356750 -- 44,121,756(+) tttga(A/G)ctttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF225 Gene

Variant ID Type Subtype PubMed ID
nsv833840 CNV Gain 17160897

Relevant External Links for ZNF225 Gene

HapMap Linkage Disequilibrium report
ZNF225

Disorders for ZNF225 Gene

No disorders were found for ZNF225 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF225 Gene

Publications for ZNF225 Gene

  1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PMID: 12743021) Shannon M. … Stubbs L. (Genome Res. 2003) 3 4
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for ZNF225 Gene

  • antibodies-online peptides for ZNF225
  • antibodies-online antibodies for ZNF225
  • antibodies-online kits for ZNF225

Sources for ZNF225 Gene

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