Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF224 Gene

protein-coding   GIFtS: 53
GCID: GC19P044598

zinc finger protein 224

(Previous names: zinc finger protein 255, zinc finger protein 27 )
(Previous symbols: ZNF255, ZNF27)
 Explore 2 diseases affiliated with
ZNF224 via our new
 Human Malady Compendium 
Biological research products
for ZNF224
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Zinc Finger Protein 2241 2     Bone Marrow Zinc Finger 22 3
KOX221 2 3 5     Zinc Finger Protein 2332 3
ZNF2551 2 3 5     Zinc Finger Protein KOX222 3
ZNF271 2 3 5     Zinc Finger 2, Bone Marrow2
Zinc Finger Protein 2551 2 3     Zinc Finger Protein 27 (KOX 22)2
BMZF-21 2 3     Zinc Finger Protein ZNF2552
BMZF22 3 5     ZNF2333
Zinc Finger Protein 271 3     

External Ids:    HGNC: 130171   Entrez Gene: 77672   Ensembl: ENSG000002676807   OMIM: 1945555   UniProtKB: Q9NZL33   

Export aliases for ZNF224 gene to outside databases

Previous GC identifers: GC19P045244 GC19P044990 GC19P049232 GC19P049290 GC19P049182 GC19P049278 GC19P041030


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ZN224_HUMAN, Q9NZL3
Function: May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may
play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport
of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells

Gene Wiki entry for ZNF224


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF224 gene promoter:
         C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF224 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF224

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF224


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.31   HGNC cytogenetic band: 19q13.2

ZNF224 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF224 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P044598:  view genomic region     (about GC identifiers)

Start:
44,598,482 bp from pter      End:
44,612,479 bp from pter
Size:
13,998 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ZN224_HUMAN, Q9NZL3 (See protein sequence)
Recommended Name: Zinc finger protein 224  
Size: 707 amino acids; 82280 Da
Subunit: Interacts with WT1. Interacts with DEPDC1A
Subcellular location: Nucleus. Note=Co-localizes with DEPDC1A at the nucleus
6/16 PDB 3D structures from and Proteopedia for ZNF224 (see all 16):
2ELY (3D)        2ELZ (3D)        2EM0 (3D)        2EM6 (3D)        2EM7 (3D)        2EM8 (3D)    
Secondary accessions: A6NFW9 P17033 Q86V10 Q8IZC8 Q9UID9 Q9Y2P6

Explore the universe of human proteins at neXtProt for ZNF224: NX_Q9NZL3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NZL3

  • ZNF224 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_037530.2  
    ENSEMBL proteins: 
     ENSP00000465000   ENSP00000337368   ENSP00000465886   ENSP00000466961  
    Reactome Protein details: Q9NZL3
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for ZNF224 
    GenScript Custom Purified and Recombinant Proteins Services for ZNF224
    Novus Biologicals ZNF224 Protein
    Novus Biologicals ZNF224 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ZNF224

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0017053transcriptional repressor complex IDA--


    ZNF224 for ontologies           About GeneDecksing



    ZNF224 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ZNF224 
    GenScript Custom Superior Antibodies Services for ZNF224
    Novus Biologicals ZNF224 Antibodies
    Search for Antibodies for ZNF224 at Abcam  
    Uscn Antibodies for ZNF224
    Search ThermoFisher Antibodies for ZNF224

    Assay Products for ZNF224: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ZNF224
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ZNF224


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ZNF224 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR001909 Krueppel-associated_box
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q9NZL3

    ProtoNet protein and cluster: Q9NZL3

    1 Blocks protein family: IPB001909 KRAB box

    UniProtKB/Swiss-Prot: ZN224_HUMAN, Q9NZL3
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 18 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ZN224_HUMAN, Q9NZL3
    Function: May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may
    play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport
    of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells

    miRNA
    Products:
        
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF224
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZNF224
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF224
    OriGene shRNA RFP: ZNF224
    OriGene siRNA: ZNF224
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF224

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ZNF224

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF224
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF224 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ZNF224 (NM_013398)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF224
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF224 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ZNF224
    Search LifeMap BioReagents cell lines for ZNF224

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF224

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--


    ZNF224 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for ZNF224:
     Decreased homologous recombina  Decreased influenza A virus in 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Generic Transcription Pathway
    Generic Transcription Pathway1.00
    Gene Expression0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    2        Reactome Pathways for ZNF224
        Generic Transcription Pathway
    Gene Expression



    ZNF224 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ZNF224

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for ZNF224 (Q9NZL33 ENSP000003373684) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRMT5O147443, ENSP000003191694I2D: score=1 STRING: ENSP00000319169
    TRIM28Q132633, ENSP000002530244I2D: score=1 STRING: ENSP00000253024
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0045892negative regulation of transcription, DNA-dependent IDA--


    ZNF224 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF224

    1 HMDB Compound for ZNF224    About this table
    CompoundSynonyms CAS #PubMed Ids
    ZincZinc (see all 2)7440-66-6--
    Search CenterWatch for drugs/clinical trials and news about ZNF224 / ZN224 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF224 gene: 
    NM_013398.2  

    Unigene Clusters for ZNF224:

    Zinc finger protein 224
    Hs.585869  [show with all ESTs], Hs.744152  [show with all ESTs]
    Unigene Representative Sequences: NR_033341, AK292500
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000589680 ENST00000590614 ENST00000589060 ENST00000336976(uc002oyh.2)
    ENST00000586978 ENST00000589870 ENST00000591511 ENST00000591551

    miRNA
    Products:
         
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF224
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ZNF224
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF224
    OriGene shRNA RFP: ZNF224
    OriGene siRNA: ZNF224
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF224
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF224
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF224 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ZNF224 (NM_013398)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF224
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF224 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF224
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF224
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF224
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF224

    Additional cDNA sequence: 

    AF187990.2 AK025777.1 AK292500.1 BC051902.1 

    7 DOTS entries:

    DT.100777983  DT.106576  DT.105246  DT.100019594  DT.40123435  DT.121451866  DT.97837730 

    24/63 AceView cDNA sequences (see all 63):

    AA554187 H38307 AL135725 AA329390 BX099636 BX486591 AA836399 BU633983 
    NM_013398 BM829337 BG211495 AY148489 BM769217 AA830099 CD000500 BM718961 
    AI811616 AL705386 AW768366 BM804721 BC051902 AA323602 T31046 BM818277 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF224 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTGGAGAAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ZNF224 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF224

    SOURCE GeneReport for Unigene clusters: Hs.585869 Hs.744152

    UniProtKB/Swiss-Prot: ZN224_HUMAN, Q9NZL3
    Tissue specificity: Ubiquitous. Mainly expressed in fetal tissues

        SABiosciences Custom PCR Arrays for ZNF224
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF224
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF224
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF224
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF224
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF224

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for ZNF224 (if available)
    TreeFam Gene Tree for ZNF224 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF224 gene
    ZNF2292  ZNF2232  ZNF2302  ENSG000000623702  ZNF1552  ZNF6642  ZNF2272  ZNF2342  
    ZNF2392  ZNF2252  ZNF2262  ZNF2142  ZNF2222  ZNF2842  ENSG000002671732  ZNF452  
    ZNF2352  ZNF2212  ENSG000002670222  ZNF2852  ZNF2332  
    18/522 SIMAP similar genes for ZNF224 using alignment to 6 protein entries:     ZN224_HUMAN (see all proteins) (see all similar genes):
    ZNF225    ZNF155    ZNF221    ZNF234    AVGR4    ZNF230
    ZNF223    WT1    ZNF763    ZNF222    ZNF705G    ZNF233
    ZNF226    ZNF124    ZNF705F    ZNF229    ZNF559    ZNF596

    ZNF224 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/360 NCBI SNPs in ZNF224 are shown (see all 360    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1158563731,2
    F,--44596534(+) CACAAC/TGCAGG 1 -- us2k11Minor allele frequency- T:0.02WA 118
    rs735582861,2
    C,--44596535(+) ACAACG/TCAGGG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1478577921,2
    --44596563(+) TATACA/GCACAC 1 -- us2k10--------
    rs764135521,2
    F,--44596585(+) TACATA/CTATAT 1 -- us2k11Minor allele frequency- C:0.09EA 120
    rs1879682601,2
    --44596613(+) ACAAAA/GTAAGT 1 -- us2k10--------
    rs778429351,2
    C,--44596690(+) TTGCTG/ATGGAA 1 -- us2k12Minor allele frequency- A:0.04WA 120
    rs133450601,2
    C,F,--44596704(+) tgtttC/Tgtggt 1 -- us2k15Minor allele frequency- T:0.21NA WA CSA 126
    rs1922138611,2
    --44596779(+) GAAAGG/TAGGTG 1 -- us2k10--------
    rs724807951,2
    C,F,--44596804(+) TGTACA/GCCACT 1 -- us2k12Minor allele frequency- G:0.12NA EA 240
    rs1153220721,2
    F,--44596867(+) CCCTCA/GATCAA 1 -- us2k11Minor allele frequency- G:0.02WA 118

    HapMap Linkage Disequilibrium report for ZNF224 (44598482 - 44612479 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ZNF224: --
    Human Gene Mutation Database (HGMD): ZNF224

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF224
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF224

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ZNF224 for disorders           About GeneDecksing

    OMIM gene information: 194555    OMIM disorders: --

    2 diseases for ZNF224:    About MalaCards
    wilms tumor    alzheimer's disease

    Human Genome Epidemiology (HuGE) Navigator: ZNF224 (3 documents)

    Export disorders for ZNF224 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF224 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with ZNF224)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cell-permeable peptide DEPDC1-ZNF224 interferes with transcriptional repression and oncogenicity in bladder cancer cells. (PubMed id 20587513)1, 2 Harada Y....Katagiri T. (2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. (PubMed id 12743021)1, 2 Shannon M.... Stubbs L. (2003)
    4. Inhibition of Wilms tumor 1 transactivation by bone marrow zinc finger 2, a novel transcriptional repressor. (PubMed id 12239212)1, 2 Lee T.H.... Pelletier J. (2002)
    5. Molecular cloning of six novel Kruppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB. (PubMed id 10585455)1, 2 Han Z.-G.... Chen Z. (1999)
    6. Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (1990)
    7. Differential expression and cellular localization of ZNF224 and ZNF255, two isoforms of the Kruppel-like zinc-finger protein family. (PubMed id 17900823)1, 9 Medugno L....Costanzo P. (2007)
    8. ZNF224: Structure and role of a multifunctional KRAB- ZFP protein. (PubMed id 21187159)1 Lupo A....Costanzo P. (2011)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Intermediate phenotypes identify divergent pathways t o Alzheimer's disease. (PubMed id 20574532)1 Shulman J.M....De Jager P.L. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7767 HGNC: 13017 AceView: ZNF224 Ensembl:ENSG00000267680 euGenes: HUgn7767
    ECgene: ZNF224 H-InvDB: ZNF224

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF224 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF224 gene:
    Search GeneIP for patents involving ZNF224

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for ZNF224  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF224   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF224  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for ZNF224   Browse 3'-UTR reporter clones for miRNA target validation  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF224   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF224  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ZNF224   OriGene Custom Protein Services for ZNF224  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF224
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF224
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF224
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF224
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF224
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF224
     GenScript Custom Purified and Recombinant Proteins Services for ZNF224 GenScript cDNA clones with any tag delivered in your preferred vector for ZNF224
     GenScript Custom Assay Services for ZNF224 GenScript Custom Superior Antibodies Services for ZNF224
     GenScript Custom overexpressing Cell Line Services for ZNF224 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ZNF224 promoter
     Search Chromatin IP Primers for ZNF224
     RT2 qPCR Primer Assay in human, mouse / rat ZNF224
     GNC Network for ZNF224
     SABiosciences Custom PCR Arrays for ZNF224
     Search Tocris compounds for ZNF224
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ZNF224 antibodies
     ZNF224 proteins
     ZNF224 lysates
     Search for Antibodies for ZNF224 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ZNF224
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     ZNF224 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ZNF224
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF224
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ZNF224
     SwitchGear Promoter luciferase reporter plasmids for ZNF224
     Search ThermoFisher Antibodies for ZNF224
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF224
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ZNF224 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4