Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF215 Gene

Aliases for ZNF215 Gene

  • Zinc Finger Protein 215 2 3
  • Zinc Finger Protein With KRAB And SCAN Domains 11 3 4
  • BWSCR2-Associated Zinc Finger Protein 2 3 4
  • ZKSCAN11 3 4
  • BAZ-2 3 4
  • BAZ2 3 4
  • ZSCAN43 3
  • BAZ 2 3

External Ids for ZNF215 Gene

Previous GeneCards Identifiers for ZNF215 Gene

  • GC11P007690
  • GC11P007408
  • GC11P006906
  • GC11P006911
  • GC11P006904
  • GC11P006606

Summaries for ZNF215 Gene

GeneCards Summary for ZNF215 Gene

ZNF215 (Zinc Finger Protein 215) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZSCAN18.

UniProtKB/Swiss-Prot for ZNF215 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF215 Gene

Genomics for ZNF215 Gene

Regulatory Elements for ZNF215 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF215 Gene

Start:
6,926,404 bp from pter
End:
6,988,487 bp from pter
Size:
62,084 bases
Orientation:
Plus strand

Genomic View for ZNF215 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF215 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF215 Gene

Proteins for ZNF215 Gene

  • Protein details for ZNF215 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UL58-ZN215_HUMAN
    Recommended name:
    Zinc finger protein 215
    Protein Accession:
    Q9UL58
    Secondary Accessions:
    • Q96C84

    Protein attributes for ZNF215 Gene

    Size:
    517 amino acids
    Molecular mass:
    60034 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF215 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF215 Gene

Proteomics data for ZNF215 Gene at MOPED

Post-translational modifications for ZNF215 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF215 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF215 Gene

Domains for ZNF215 Gene

Gene Families for ZNF215 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF215 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UL58

UniProtKB/Swiss-Prot:

ZN215_HUMAN :
  • Q9UL58
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF215: view

Function for ZNF215 Gene

Molecular function for ZNF215 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF215 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IBA --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity NAS 10762538
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF215: view

Animal Model Products

CRISPR Products

miRNA for ZNF215 Gene

miRTarBase miRNAs that target ZNF215

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF215 Gene

Localization for ZNF215 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF215 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF215 Gene COMPARTMENTS Subcellular localization image for ZNF215 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF215 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF215: view

Pathways for ZNF215 Gene

SuperPathways for ZNF215 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF215: view

Pathways by source for ZNF215 Gene

2 Reactome pathways for ZNF215 Gene

Interacting Proteins for ZNF215 Gene

Gene Ontology (GO) - Biological Process for ZNF215 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF215: view

Transcripts for ZNF215 Gene

Unigene Clusters for ZNF215 Gene

Zinc finger protein 215:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF215

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF215
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF215 Gene

No ASD Table

Relevant External Links for ZNF215 Gene

GeneLoc Exon Structure for
ZNF215
ECgene alternative splicing isoforms for
ZNF215

Expression for ZNF215 Gene

mRNA expression in normal human tissues for ZNF215 Gene

SOURCE GeneReport for Unigene cluster for ZNF215 Gene Hs.523457

genes like me logo Genes that share expressions with ZNF215: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF215 Gene

Orthologs for ZNF215 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF215 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF215 35
  • 99.23 (n)
  • 98.26 (a)
ZNF215 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF215 35
  • 85.12 (n)
  • 74.66 (a)
ZNF215 36
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF215 35
  • 84.6 (n)
  • 72.43 (a)
ZNF215 36
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 44 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 31 (a)
OneToMany
Species with no ortholog for ZNF215:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF215 Gene

ENSEMBL:
Gene Tree for ZNF215 (if available)
TreeFam:
Gene Tree for ZNF215 (if available)

Paralogs for ZNF215 Gene

Paralogs for ZNF215 Gene

Pseudogenes.org Pseudogenes for ZNF215 Gene

genes like me logo Genes that share paralogs with ZNF215: view

Variants for ZNF215 Gene

Sequence variations from dbSNP and Humsavar for ZNF215 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs762853 -- 6,983,695(-) AACAA(C/G)TTTAA intron-variant
rs762854 -- 6,983,663(-) ATTTC(C/T)ACTTC intron-variant
rs957747 -- 6,945,583(-) AGGAA(C/T)GTCTC intron-variant
rs957748 -- 6,945,477(-) gggta(C/T)ggaat intron-variant
rs969651 -- 6,977,404(-) CATCT(A/G)TATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF215 Gene

Variant ID Type Subtype PubMed ID
nsv832061 CNV Loss 17160897
nsv896973 CNV Loss 21882294
esv2557168 CNV Deletion 19546169
nsv896974 CNV Loss 21882294

Relevant External Links for ZNF215 Gene

HapMap Linkage Disequilibrium report
ZNF215

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF215 Gene

Disorders for ZNF215 Gene

(2) University of Copenhagen DISEASES for ZNF215 Gene

genes like me logo Genes that share disorders with ZNF215: view

No data available for UniProtKB/Swiss-Prot for ZNF215 Gene

Publications for ZNF215 Gene

  1. Disruption of a novel imprinted zinc-finger gene, ZNF215, in Beckwith-Wiedemann syndrome. (PMID: 10762538) Alders M. … Mannens M. (Am. J. Hum. Genet. 2000) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  5. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PMID: 22939624) Taipale M. … Lindquist S. (Cell 2012) 3

Products for ZNF215 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF215
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF215
  • Block miRNA regulation of ZNF215 using miScript Target Protectors

Sources for ZNF215 Gene

Back to Top

Content