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Aliases for ZNF214 Gene

Aliases for ZNF214 Gene

  • Zinc Finger Protein 214 2 3
  • BWSCR2-Associated Zinc Finger Protein 1 3 4
  • BAZ-1 3 4
  • BAZ1 3 4
  • BAZ 1 3

External Ids for ZNF214 Gene

Summaries for ZNF214 Gene

GeneCards Summary for ZNF214 Gene

ZNF214 (Zinc Finger Protein 214) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF155.

UniProtKB/Swiss-Prot for ZNF214 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF214 Gene

Genomics for ZNF214 Gene

Genomic Location for ZNF214 Gene

Start:
6,999,318 bp from pter
End:
7,020,368 bp from pter
Size:
21,051 bases
Orientation:
Minus strand

Genomic View for ZNF214 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF214 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF214 Gene

Regulatory Elements for ZNF214 Gene

Proteins for ZNF214 Gene

  • Protein details for ZNF214 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UL59-ZN214_HUMAN
    Recommended name:
    Zinc finger protein 214
    Protein Accession:
    Q9UL59
    Secondary Accessions:
    • B2R8Q1

    Protein attributes for ZNF214 Gene

    Size:
    606 amino acids
    Molecular mass:
    70992 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF214 Gene

Proteomics data for ZNF214 Gene at MOPED

Post-translational modifications for ZNF214 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF214 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF214 Gene

Domains for ZNF214 Gene

Gene Families for ZNF214 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN214_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q9UL59
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9UL59
Similarity:
  • Contains 11 C2H2-type zinc fingers.:
    • Q9UL59
genes like me logo Genes that share domains with ZNF214: view

Function for ZNF214 Gene

Molecular function for ZNF214 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF214 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0008270 zinc ion binding NAS 10762538
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with ZNF214: view

miRNA for ZNF214 Gene

miRTarBase miRNAs that target ZNF214

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF214 Gene

Localization for ZNF214 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF214 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF214 Gene COMPARTMENTS Subcellular localization image for ZNF214 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF214 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF214: view

Pathways for ZNF214 Gene

SuperPathways for ZNF214 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF214: view

Pathways by source for ZNF214 Gene

2 Reactome pathways for ZNF214 Gene

Interacting Proteins for ZNF214 Gene

Gene Ontology (GO) - Biological Process for ZNF214 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF214: view

Transcripts for ZNF214 Gene

mRNA/cDNA for ZNF214 Gene

Unigene Clusters for ZNF214 Gene

Zinc finger protein 214:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF214 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d
SP1: -
SP2: - -
SP3: - -
SP4:
SP5: - -

Relevant External Links for ZNF214 Gene

GeneLoc Exon Structure for
ZNF214
ECgene alternative splicing isoforms for
ZNF214

Expression for ZNF214 Gene

mRNA expression in normal human tissues for ZNF214 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF214 Gene

SOURCE GeneReport for Unigene cluster for ZNF214 Gene Hs.733636

genes like me logo Genes that share expressions with ZNF214: view

Orthologs for ZNF214 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF214 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF214 36
  • 99.34 (n)
  • 98.84 (a)
ZNF214 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF214 36
  • 86.67 (n)
  • 80 (a)
ZNF214 37
  • 79 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF214 36
  • 88.5 (n)
  • 84.49 (a)
ZNF214 37
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm13242 37
  • 33 (a)
ManyToMany
Gm14443 37
  • 38 (a)
ManyToMany
Gm26919 37
  • 27 (a)
ManyToMany
Rex2 37
  • 32 (a)
ManyToMany
Zfp109 37
  • 35 (a)
ManyToMany
Zfp229 37
  • 32 (a)
ManyToMany
Zfp53 37
  • 35 (a)
ManyToMany
Zfp54 37
  • 32 (a)
ManyToMany
Zfp677 37
  • 35 (a)
ManyToMany
Zfp760 37
  • 33 (a)
ManyToMany
Zfp948 37
  • 30 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 30 (a)
ManyToMany
-- 37
  • 37 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
-- 37
  • 48 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 47 (a)
ManyToMany
-- 37
  • 34 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 37
  • 43 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 36 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ZNF214 37
  • 11 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG5245 37
  • 32 (a)
ManyToMany
CG11695 38
  • 29 (a)
CG2120 38
  • 35 (a)
worm
(Caenorhabditis elegans)
Secernentea C27A12.2 37
  • 18 (a)
ManyToMany
tag-146 37
  • 21 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 23 (a)
ManyToMany
-- 37
  • 42 (a)
ManyToMany
Species with no ortholog for ZNF214:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF214 Gene

ENSEMBL:
Gene Tree for ZNF214 (if available)
TreeFam:
Gene Tree for ZNF214 (if available)

Paralogs for ZNF214 Gene

Selected SIMAP similar genes for ZNF214 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF214: view

Variants for ZNF214 Gene

Sequence variations from dbSNP and Humsavar for ZNF214 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1156525 - 7,001,300(+) TCCTG(A/C/T)GACTT missense, reference
rs1156526 - 7,001,486(+) GCCAG(C/T)AGGAA reference, missense, utr-variant-5-prime
rs2035845 -- 7,017,019(-) CATTT(C/G)TCATA intron-variant
rs2087719 -- 7,008,610(+) agaaa(G/T)aaaag intron-variant
rs2239734 - 7,001,129(-) GCTCA(G/T)AGTTC missense, reference

Structural Variations from Database of Genomic Variants (DGV) for ZNF214 Gene

Variant ID Type Subtype PubMed ID
nsv832061 CNV Loss 17160897

Relevant External Links for ZNF214 Gene

HapMap Linkage Disequilibrium report
ZNF214

Disorders for ZNF214 Gene

(2) University of Copenhagen DISEASES for ZNF214 Gene

genes like me logo Genes that share disorders with ZNF214: view

No data available for UniProtKB/Swiss-Prot for ZNF214 Gene

Publications for ZNF214 Gene

  1. Disruption of a novel imprinted zinc-finger gene, ZNF215, in Beckwith-Wiedemann syndrome. (PMID: 10762538) Alders M. … Mannens M. (Am. J. Hum. Genet. 2000) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Reduced transcript expression of genes affected by inherited and de novo CNVs in autism. (PMID: 21448237) Nord A.S. … McClellan J.M. (Eur. J. Hum. Genet. 2011) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for ZNF214 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF214
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF214
    • Block miRNA regulation of ZNF214 using miScript Target Protectors

    Sources for ZNF214 Gene

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