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ZNF213 Gene

protein-coding   GIFtS: 51
GCID: GC16P003179

Zinc Finger Protein 213

  See ZNF213-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 2131 2
Putative Transcription Factor CR532 3
Zinc Finger Protein With KRAB And SCAN Domains 212 3
ZKSCAN212 3
CR532 5
ZSCAN532

External Ids:    HGNC: 130051   Entrez Gene: 77602   Ensembl: ENSG000000856447   OMIM: 6083875   UniProtKB: O147713   

Export aliases for ZNF213 gene to outside databases

Previous GC identifers: GC16P003205 GC16P003185 GC16P003124 GC16P003126 GC16P003156


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZNF213 Gene:
C2H2 zinc finger proteins, such as ZNF213, have bipartite structures in which one domain binds DNA or RNA and the
other modulates target gene expression.(supplied by OMIM, Apr 2004)

GeneCards Summary for ZNF213 Gene:
ZNF213 (zinc finger protein 213) is a protein-coding gene. Diseases associated with ZNF213 include patent ductus arteriosus. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF446.

UniProtKB/Swiss-Prot: ZN213_HUMAN, O14771
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_010393.17  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF213 gene promoter:
         Nkx2-5   NF-E2   NF-E2 p45   AP-2alpha   LCR-F1   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF213 promoter sequence
   Search Chromatin IP Primers for ZNF213

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF213


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

ZNF213 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF213 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P003179:  view genomic region     (about GC identifiers)

Start:
3,179,778 bp from pter      End:
3,192,806 bp from pter
Size:
13,029 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZN213_HUMAN, O14771 (See protein sequence)
Recommended Name: Zinc finger protein 213  
Size: 459 amino acids; 51263 Da
Sequence caution: Sequence=AAB70531.1; Type=Frameshift; Positions=400, 405, 457;
Secondary accessions: A8K1B9 Q96IS1

Explore the universe of human proteins at neXtProt for ZNF213: NX_O14771

Explore proteomics data for ZNF213 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF213 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001128127.1  NP_004211.1  

    ENSEMBL proteins: 
     ENSP00000459967   ENSP00000460157   ENSP00000380087   ENSP00000459177   ENSP00000461024  
     ENSP00000459233   ENSP00000459293   ENSP00000403892  
    Reactome Protein details: O14771

    ZNF213 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZNF213

     
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    antibodies-online proteins for ZNF213 (4 products) 

     
    antibodies-online peptides for ZNF213

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    antibodies-online antibodies for ZNF213 (22 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 6):
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd

    Graphical View of Domain Structure for InterPro Entry O14771

    ProtoNet protein and cluster: O14771

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN


    UniProtKB/Swiss-Prot: ZN213_HUMAN, O14771
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 5 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain
    Similarity: Contains 1 SCAN box domain


    Find genes that share domains with ZNF213           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN213_HUMAN, O14771
    Function: May be involved in transcriptional regulation

         Genatlas biochemistry entry for ZNF213:
    zinc finger protein 213 (C2H2 type,Kruppel-like),ubiquitously expressed

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF213           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZNF213

    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate ZNF213:
    hsa-miR-4265 hsa-miR-124 hsa-miR-449c* hsa-miR-506 hsa-miR-4296
    SwitchGear 3'UTR luciferase reporter plasmidZNF213 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ZNF213

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN213_HUMAN, O14771: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZNF213           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF213 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF213           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF213
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF213
    Interactions:

        Search GeneGlobe Interaction Network for ZNF213

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----

    Find genes that share ontologies with ZNF213           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF213 (ZN213)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF213 gene (2 alternative transcripts): 
    NM_001134655.1  NM_004220.2  

    Unigene Cluster for ZNF213:

    Zinc finger protein 213
    Hs.115284  [show with all ESTs]
    Unigene Representative Sequence: AK055337
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000573771 ENST00000574902 ENST00000396878(uc010uws.2 uc002cud.3 uc010bth.3)
    ENST00000576416 ENST00000574928(uc010btf.3) ENST00000576863(uc010uwt.2)
    ENST00000572647 ENST00000574575 ENST00000416391
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate ZNF213:
    hsa-miR-4265 hsa-miR-124 hsa-miR-449c* hsa-miR-506 hsa-miR-4296
    SwitchGear 3'UTR luciferase reporter plasmidZNF213 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat ZNF213
      QuantiFast Probe-based Assays in human, mouse, rat ZNF213

    Additional mRNA sequence: 

    AF017433.1 AK055337.1 AK289834.1 AK291789.1 AK297454.1 BC007287.1 BC007598.1 BC012772.2 
    BC080572.1 

    7 DOTS entries:

    DT.100789991  DT.99953934  DT.95327378  DT.97845601  DT.105522  DT.120661143  DT.95297638 

    Selected AceView cDNA sequences (see all 83):

    AI474497 BM461723 BF916366 BE274943 BQ930371 BQ931481 BF510572 BM974318 
    BX280382 BC080572 BU734878 BG574413 BM916949 BM705589 BE387349 BF528452 
    BU537966 BI064016 BI063870 BI063871 BQ073702 BI117748 CB131471 AI197807 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF213    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b
    SP1:              -                 -                                 
    SP2:              -                                                   
    SP3:                                                                  
    SP4:                                            -     -               


    ECgene alternative splicing isoforms for ZNF213

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF213 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACAGGGACA
    ZNF213 Expression
    About this image

    ZNF213 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF213 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.115284

    UniProtKB/Swiss-Prot: ZN213_HUMAN, O14771
    Tissue specificity: Widely expressed with highest levels in testis

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZNF213 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Zfp2131 , 5 zinc finger protein 2131, 5 80.24(n)1
    75.88(a)1
      17 (11.67 cM)5
    4495211  NM_001033496.31  NP_001028668.21 
     235567695 


    ENSEMBL Gene Tree for ZNF213 (if available)
    TreeFam Gene Tree for ZNF213 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF213 gene
    ZNF4462  ZSCAN92  ZKSCAN12  ZNF3972  ZNF5002  ZNF2322  ZSCAN302  ZNF1742  
    ZNF32  ZKSCAN42  ZNF3962  ZSCAN122  ZNF3942  ZSCAN232  ZSCAN212  ZNF1652  
    ZSCAN162  ZKSCAN82  ZSCAN222  ZSCAN312  ZNF242  ZKSCAN32  ZNF182  
    Selected SIMAP similar genes for ZNF213 using alignment to 7 protein entries:     ZN213_HUMAN (see all proteins) (see all similar genes):
    kr-znf3    ZSCAN29    ZNF396    SCAND1    ZNF160    ZNF818P
    ZSCAN30    HZF36    ZNF774    ZNF78L1    ZNF852    ZNF665
    ZNF501    ZNF551    ZNF883    ZSCAN10    HZF30    ZIK1

    Find genes that share paralogs with ZNF213           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF213 (see all 192)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1831267701,2
    --3187027(+) GTCACA/GTGAGC 2 -- int10--------
    rs1468347481,2
    C--3187036(+) GCAAGA/GCATTA 2 -- int10--------
    rs1867339571,2
    --3187075(+) CATGAA/GAGGAT 2 -- int10--------
    rs1911973591,2
    --3187077(+) TGAAAA/GGATGG 2 -- int10--------
    rs1434873231,2
    C,F--3187372(+) AACAGG/CAATCT 4 /Q /E mis12Minor allele frequency- C:0.00NA EU 5821
    rs71972701,2
    C,F,A,H--3187431(+) CGGCAA/GTTCTG 4 Q syn1 ese313Minor allele frequency- G:0.02NS NA WA EU 7189
    rs2021429181,2
    C--3187472(+) CTTCAG/ACCAGC 4 /N /S mis11Minor allele frequency- A:0.00EU 1323
    rs1998748781,2
    C--3187618(+) GAAGCA/GGTGAG 4 S G mis10--------
    rs749477981,2
    C,F--3187632(+) GCTGTC/TGCCTT 4 V syn12Minor allele frequency- T:0.01EA NA 402
    rs1149345281,2
    --3187676(+) CTGGCG/AACAGG 4 /Q /R mis11Minor allele frequency- A:0.01NA 196

    HapMap Linkage Disequilibrium report for ZNF213 (3179778 - 3192806 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ZNF213 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1496729CNV Insertion17803354
    nsv509589CNV Insertion20534489
    nsv103291CNV Insertion16902084
    dgv2581n71CNV Loss21882294
    dgv2580n71CNV Loss21882294
    nsv905170CNV Loss21882294
    nsv905185CNV Loss21882294
    nsv905207CNV Loss21882294
    dgv2582n71CNV Loss21882294
    nsv905208CNV Loss21882294

    Human Gene Mutation Database (HGMD): ZNF213
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF213
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF213

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608387    OMIM disorders: --

    1 disease for ZNF213:    
    About MalaCards
    patent ductus arteriosus

    1 disease from the University of Copenhagen DISEASES database for ZNF213:
    Patent ductus arteriosus

    Find genes that share disorders with ZNF213           About GenesLikeMe


    Export disorders for ZNF213 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF213 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZNF213)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of a zinc finger gene (ZNF213) from 16p13.3. (PubMed id 10023065)1, 2, 3 Chen X.... Fischel-Ghodsian N. (Biochim. Biophys. Acta 1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A transcriptional map of the FMF region. (PubMed id 9653642)1, 3 Bernot A.... Weissenbach J. (Genomics 1998)
    5. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? (PubMed id 23314748)1 Nathan J.A....Goldberg A.L. (EMBO J. 2013)
    6. Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study. (PubMed id 23934736)1 Yu B....Boerwinkle E. (Genet. Epidemiol. 2013)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 7760 HGNC: 13005 AceView: ZNF213 Ensembl:ENSG00000085644 euGenes: HUgn7760
    ECgene: ZNF213 H-InvDB: ZNF213

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZNF213 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF213 gene:
    Search GeneIP for patents involving ZNF213

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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