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Aliases for ZNF213 Gene

Aliases for ZNF213 Gene

  • Zinc Finger Protein 213 2 3
  • Zinc Finger Protein With KRAB And SCAN Domains 21 3 4
  • Putative Transcription Factor CR53 3 4
  • ZKSCAN21 3 4
  • CR53 3 6
  • ZSCAN53 3

External Ids for ZNF213 Gene

Previous GeneCards Identifiers for ZNF213 Gene

  • GC16P003205
  • GC16P003185
  • GC16P003124
  • GC16P003126
  • GC16P003156
  • GC16P003179

Summaries for ZNF213 Gene

Entrez Gene Summary for ZNF213 Gene

  • C2H2 zinc finger proteins, such as ZNF213, have bipartite structures in which one domain binds DNA or RNA and the other modulates target gene expression.[supplied by OMIM, Apr 2004]

GeneCards Summary for ZNF213 Gene

ZNF213 (Zinc Finger Protein 213) is a Protein Coding gene. Diseases associated with ZNF213 include patent ductus arteriosus. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF396.

UniProtKB/Swiss-Prot for ZNF213 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF213 Gene

Genomics for ZNF213 Gene

Regulatory Elements for ZNF213 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF213 Gene

Start:
3,129,777 bp from pter
End:
3,142,805 bp from pter
Size:
13,029 bases
Orientation:
Plus strand

Genomic View for ZNF213 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF213 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF213 Gene

Proteins for ZNF213 Gene

  • Protein details for ZNF213 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O14771-ZN213_HUMAN
    Recommended name:
    Zinc finger protein 213
    Protein Accession:
    O14771
    Secondary Accessions:
    • A8K1B9
    • B4DMG6
    • Q96IS1

    Protein attributes for ZNF213 Gene

    Size:
    459 amino acids
    Molecular mass:
    51263 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAB70531.1; Type=Frameshift; Positions=400, 405, 457; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF213 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF213 Gene

Proteomics data for ZNF213 Gene at MOPED

Post-translational modifications for ZNF213 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF213 Gene

No data available for DME Specific Peptides for ZNF213 Gene

Domains for ZNF213 Gene

Gene Families for ZNF213 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF213 Gene

Graphical View of Domain Structure for InterPro Entry

O14771

UniProtKB/Swiss-Prot:

ZN213_HUMAN :
  • O14771
Domain:
  • Contains 1 KRAB domain.
  • Contains 1 SCAN box domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF213: view

Function for ZNF213 Gene

Molecular function for ZNF213 Gene

GENATLAS Biochemistry: zinc finger protein 213 (C2H2 type,Kruppel-like),ubiquitously expressed
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF213 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF213: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF213 Gene

Localization for ZNF213 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF213 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF213 Gene COMPARTMENTS Subcellular localization image for ZNF213 gene
Compartment Confidence
nucleus 3
cytosol 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF213 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF213: view

Pathways for ZNF213 Gene

SuperPathways for ZNF213 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF213: view

Pathways by source for ZNF213 Gene

2 Reactome pathways for ZNF213 Gene

Interacting Proteins for ZNF213 Gene

Gene Ontology (GO) - Biological Process for ZNF213 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF213: view

Transcripts for ZNF213 Gene

Unigene Clusters for ZNF213 Gene

Zinc finger protein 213:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF213

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF213 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b
SP1: - -
SP2: -
SP3:
SP4: - -

Relevant External Links for ZNF213 Gene

GeneLoc Exon Structure for
ZNF213
ECgene alternative splicing isoforms for
ZNF213

Expression for ZNF213 Gene

mRNA expression in normal human tissues for ZNF213 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF213 Gene

SOURCE GeneReport for Unigene cluster for ZNF213 Gene Hs.115284

mRNA Expression by UniProt/SwissProt for ZNF213 Gene

O14771-ZN213_HUMAN
Tissue specificity: Widely expressed with highest levels in testis.
genes like me logo Genes that share expressions with ZNF213: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF213 Gene

Orthologs for ZNF213 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF213 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF213 35
  • 99.35 (n)
  • 98.91 (a)
ZNF213 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF213 35
  • 85.89 (n)
  • 82.68 (a)
ZNF213 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF213 35
  • 85.01 (n)
  • 81.66 (a)
mouse
(Mus musculus)
Mammalia Zfp213 35
  • 80.24 (n)
  • 75.88 (a)
Zfp213 16
Zfp213 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF213 36
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF213 36
  • 69 (a)
OneToOne
Species with no ortholog for ZNF213:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF213 Gene

ENSEMBL:
Gene Tree for ZNF213 (if available)
TreeFam:
Gene Tree for ZNF213 (if available)

Paralogs for ZNF213 Gene

Selected SIMAP similar genes for ZNF213 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF213: view

Variants for ZNF213 Gene

Sequence variations from dbSNP and Humsavar for ZNF213 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs172792 -- 3,139,444(+) AGGCA(C/T)AGTTG intron-variant
rs224246 -- 3,139,378(+) TTTAC(A/G)CATAA intron-variant
rs224247 -- 3,141,482(+) TCGGA(A/G)CTCGC utr-variant-3-prime, nc-transcript-variant
rs224248 -- 3,141,507(+) TCTGA(A/G)GACCT utr-variant-3-prime, nc-transcript-variant
rs2238377 -- 3,140,334(+) CTTCT(A/G)CCTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF213 Gene

Variant ID Type Subtype PubMed ID
nsv905170 CNV Loss 21882294
nsv905185 CNV Loss 21882294
nsv509589 CNV Insertion 20534489
dgv2580n71 CNV Loss 21882294
nsv457355 CNV Gain 19166990
dgv2581n71 CNV Loss 21882294
dgv2582n71 CNV Loss 21882294
nsv905207 CNV Loss 21882294
nsv905208 CNV Loss 21882294
esv1496729 CNV Insertion 17803354
nsv103291 CNV Insertion 16902084

Relevant External Links for ZNF213 Gene

HapMap Linkage Disequilibrium report
ZNF213
Human Gene Mutation Database (HGMD)
ZNF213

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF213 Gene

Disorders for ZNF213 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for ZNF213 Gene including...

Search for ZNF213 Gene in MalaCards »

(1) University of Copenhagen DISEASES for ZNF213 Gene

genes like me logo Genes that share disorders with ZNF213: view

No data available for UniProtKB/Swiss-Prot for ZNF213 Gene

Publications for ZNF213 Gene

  1. Identification and characterization of a zinc finger gene (ZNF213) from 16p13.3. (PMID: 10023065) Chen X. … Fischel-Ghodsian N. (Biochim. Biophys. Acta 1999) 2 3 4
  2. A transcriptional map of the FMF region. (PMID: 9653642) Bernot A. … Weissenbach J. (Genomics 1998) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF213 Gene

Sources for ZNF213 Gene

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