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Aliases for ZNF212 Gene

Aliases for ZNF212 Gene

  • Zinc Finger Protein 212 2 3 5
  • Zinc Finger Protein C2H2-150 3 4
  • ZNFC150 3 4
  • C2H2-150 3
  • ZNF182 3

External Ids for ZNF212 Gene

Previous GeneCards Identifiers for ZNF212 Gene

  • GC07P147194
  • GC07P148251
  • GC07P148328
  • GC07P148374
  • GC07P148567
  • GC07P148936
  • GC07P143014

Summaries for ZNF212 Gene

Entrez Gene Summary for ZNF212 Gene

  • This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF212 Gene

ZNF212 (Zinc Finger Protein 212) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription cofactor activity. An important paralog of this gene is ZNF746.

UniProtKB/Swiss-Prot for ZNF212 Gene

  • May be involved in transcriptional regulation.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF212 Gene

Genomics for ZNF212 Gene

Regulatory Elements for ZNF212 Gene

Enhancers for ZNF212 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF212 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF212 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF212 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF212 Gene

149,239,648 bp from pter
149,255,609 bp from pter
15,962 bases
Plus strand

Genomic View for ZNF212 Gene

Genes around ZNF212 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF212 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF212 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF212 Gene

Proteins for ZNF212 Gene

  • Protein details for ZNF212 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 212
    Protein Accession:
    Secondary Accessions:
    • B2RCF4
    • Q13396
    • Q8N664

    Protein attributes for ZNF212 Gene

    495 amino acids
    Molecular mass:
    55447 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC51296.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAD45826.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF212 Gene

Proteomics data for ZNF212 Gene at MOPED

Post-translational modifications for ZNF212 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF212 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF212 Gene

Domains & Families for ZNF212 Gene

Gene Families for ZNF212 Gene

Protein Domains for ZNF212 Gene

Suggested Antigen Peptide Sequences for ZNF212 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 4 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF212: view

Function for ZNF212 Gene

Molecular function for ZNF212 Gene

GENATLAS Biochemistry:
zinc finger protein 122,KRAB subfamily (C2H2 Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF212 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with ZNF212: view
genes like me logo Genes that share phenotypes with ZNF212: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF212 Gene

Localization for ZNF212 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF212 Gene

Subcellular locations from

Jensen Localization Image for ZNF212 Gene COMPARTMENTS Subcellular localization image for ZNF212 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF212 Gene

Pathways & Interactions for ZNF212 Gene

SuperPathways for ZNF212 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF212: view

Pathways by source for ZNF212 Gene

2 Reactome pathways for ZNF212 Gene

Gene Ontology (GO) - Biological Process for ZNF212 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IEA,NAS 7633419
genes like me logo Genes that share ontologies with ZNF212: view

No data available for SIGNOR curated interactions for ZNF212 Gene

Drugs & Compounds for ZNF212 Gene

No Compound Related Data Available

Transcripts for ZNF212 Gene

mRNA/cDNA for ZNF212 Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF212 Gene

Zinc finger protein 212:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF212 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c
SP1: - -
SP2: - - -
SP3: -
SP4: - - -
SP5: - - -
SP7: - - -
SP8: - - - -
SP9: - - -

Relevant External Links for ZNF212 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF212 Gene

mRNA expression in normal human tissues for ZNF212 Gene

Protein differential expression in normal tissues from HIPED for ZNF212 Gene

This gene is overexpressed in Liver, secretome (57.2) and Peripheral blood mononuclear cells (10.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF212 Gene

SOURCE GeneReport for Unigene cluster for ZNF212 Gene Hs.490510

genes like me logo Genes that share expression patterns with ZNF212: view

Protein tissue co-expression partners for ZNF212 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF212 Gene

Orthologs for ZNF212 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF212 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF212 35
  • 83.19 (n)
  • 78.03 (a)
ZNF212 36
  • 77 (a)
(Canis familiaris)
Mammalia ZNF212 35
  • 87.07 (n)
  • 86.26 (a)
(Mus musculus)
Mammalia Zfp212 35
  • 82.21 (n)
  • 80.04 (a)
Zfp212 16
Zfp212 36
  • 80 (a)
(Pan troglodytes)
Mammalia ZNF212 35
  • 99.19 (n)
  • 99.39 (a)
ZNF212 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zfp212 35
  • 81.33 (n)
  • 80.04 (a)
(Monodelphis domestica)
Mammalia ZNF212 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF212 36
  • 49 (a)
(Gallus gallus)
Aves -- 36
  • 24 (a)
(Anolis carolinensis)
Reptilia ZNF212 36
  • 29 (a)
Species with no ortholog for ZNF212:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF212 Gene

Gene Tree for ZNF212 (if available)
Gene Tree for ZNF212 (if available)

Paralogs for ZNF212 Gene

Paralogs for ZNF212 Gene

genes like me logo Genes that share paralogs with ZNF212: view

Variants for ZNF212 Gene

Sequence variations from dbSNP and Humsavar for ZNF212 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs34185245 - 149,253,804(-) CCTAT(A/G)AGATT reference, missense
rs886674 -- 149,248,186(+) attgg(A/G)aatac intron-variant, upstream-variant-2KB
rs1053297 -- 149,253,924(+) TGGCC(A/G)CACAT reference, missense
rs1053298 -- 149,254,901(+) CTGAA(G/T)AACCT utr-variant-3-prime
rs1202427 -- 149,240,045(+) TCTGA(A/C)GCTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF212 Gene

Variant ID Type Subtype PubMed ID
nsv889402 CNV Loss 21882294
nsv465196 CNV Loss 19166990
nsv819456 CNV Gain 19587683

Variation tolerance for ZNF212 Gene

Residual Variation Intolerance Score: 68.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.77; 73.50% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF212 Gene

Disorders for ZNF212 Gene

Relevant External Links for ZNF212

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF212 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF212 Gene

Publications for ZNF212 Gene

  1. Molecular cloning and mapping of a novel human KRAB domain-containing C2H2-type zinc finger to chromosome 7q36.1. (PMID: 9169157) Becker K.G. … Drew P.D. (Genomics 1997) 2 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3
  4. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3
  5. A protein-protein interaction network of transcription factors acting during liver cell proliferation. (PMID: 18255255) Gao J. … Yu Y. (Genomics 2008) 3

Products for ZNF212 Gene

Sources for ZNF212 Gene