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Aliases for ZNF212 Gene

Aliases for ZNF212 Gene

  • Zinc Finger Protein 212 2 3
  • ZNFC150 3 4 6
  • Zinc Finger Protein C2H2-150 3 4
  • ZNF182 3 6
  • C2H2-150 3

External Ids for ZNF212 Gene

Previous GeneCards Identifiers for ZNF212 Gene

  • GC07P147194
  • GC07P148251
  • GC07P148328
  • GC07P148374
  • GC07P148567
  • GC07P148936
  • GC07P143014

Summaries for ZNF212 Gene

Entrez Gene Summary for ZNF212 Gene

  • This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF212 Gene

ZNF212 (Zinc Finger Protein 212) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include identical protein binding. An important paralog of this gene is ZNF746.

UniProtKB/Swiss-Prot for ZNF212 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF212 Gene

Genomics for ZNF212 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF212 Gene

Start:
149,239,651 bp from pter
End:
149,255,609 bp from pter
Size:
15,959 bases
Orientation:
Plus strand

Genomic View for ZNF212 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF212 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF212 Gene

Proteins for ZNF212 Gene

  • Protein details for ZNF212 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UDV6-ZN212_HUMAN
    Recommended name:
    Zinc finger protein 212
    Protein Accession:
    Q9UDV6
    Secondary Accessions:
    • B2RCF4
    • Q13396
    • Q8N664

    Protein attributes for ZNF212 Gene

    Size:
    495 amino acids
    Molecular mass:
    55447 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC51296.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAD45826.2; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF212 Gene

Proteomics data for ZNF212 Gene at MOPED

Post-translational modifications for ZNF212 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF212 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF212 Gene

Domains for ZNF212 Gene

Gene Families for ZNF212 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF212 Gene

Suggested Antigen Peptide Sequences for ZNF212 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UDV6

UniProtKB/Swiss-Prot:

ZN212_HUMAN :
  • Q9UDV6
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF212: view

Function for ZNF212 Gene

Molecular function for ZNF212 Gene

GENATLAS Biochemistry: zinc finger protein 122,KRAB subfamily (C2H2 Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF212 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003712 transcription cofactor activity IBA --
GO:0005515 protein binding IPI 18255255
GO:0008270 zinc ion binding NAS 7633419
genes like me logo Genes that share ontologies with ZNF212: view

Animal Model Products

CRISPR Products

miRNA for ZNF212 Gene

miRTarBase miRNAs that target ZNF212

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF212 Gene

Localization for ZNF212 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF212 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF212 Gene COMPARTMENTS Subcellular localization image for ZNF212 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF212 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with ZNF212: view

Pathways for ZNF212 Gene

SuperPathways for ZNF212 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF212: view

Pathways by source for ZNF212 Gene

2 Reactome pathways for ZNF212 Gene

Gene Ontology (GO) - Biological Process for ZNF212 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS 7633419
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF212: view

Transcripts for ZNF212 Gene

mRNA/cDNA for ZNF212 Gene

(3) Selected AceView cDNA sequences:
(4) Additional mRNA sequences :
(4) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF212 Gene

Zinc finger protein 212:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF212

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF212 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c
SP1: - -
SP2: - - -
SP3: -
SP4: - - -
SP5: - - -
SP6:
SP7: - - -
SP8: - - - -
SP9: - - -

Relevant External Links for ZNF212 Gene

GeneLoc Exon Structure for
ZNF212
ECgene alternative splicing isoforms for
ZNF212

Expression for ZNF212 Gene

mRNA expression in normal human tissues for ZNF212 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF212 Gene

SOURCE GeneReport for Unigene cluster for ZNF212 Gene Hs.490510

genes like me logo Genes that share expressions with ZNF212: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF212 Gene

Orthologs for ZNF212 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF212 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF212 35
  • 99.19 (n)
  • 99.39 (a)
ZNF212 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF212 35
  • 83.19 (n)
  • 78.03 (a)
ZNF212 36
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF212 35
  • 87.07 (n)
  • 86.26 (a)
mouse
(Mus musculus)
Mammalia Zfp212 35
  • 82.21 (n)
  • 80.04 (a)
Zfp212 16
Zfp212 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF212 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF212 36
  • 49 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp212 35
  • 81.33 (n)
  • 80.04 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 24 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia ZNF212 36
  • 29 (a)
OneToOne
Species with no ortholog for ZNF212:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF212 Gene

ENSEMBL:
Gene Tree for ZNF212 (if available)
TreeFam:
Gene Tree for ZNF212 (if available)

Paralogs for ZNF212 Gene

Paralogs for ZNF212 Gene

genes like me logo Genes that share paralogs with ZNF212: view

Variants for ZNF212 Gene

Sequence variations from dbSNP and Humsavar for ZNF212 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs38527 -- 149,244,510(+) gggtt(A/T)cacca intron-variant
rs38528 -- 149,246,576(+) agaga(C/T)ggggt intron-variant
rs886674 -- 149,248,186(+) attgg(A/G)aatac intron-variant, upstream-variant-2KB
rs1053297 -- 149,253,924(+) TGGCC(A/G)CACAT reference, missense
rs1053298 -- 149,254,901(+) CTGAA(G/T)AACCT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF212 Gene

Variant ID Type Subtype PubMed ID
nsv889402 CNV Loss 21882294
nsv465196 CNV Loss 19166990
nsv819456 CNV Gain 19587683

Relevant External Links for ZNF212 Gene

HapMap Linkage Disequilibrium report
ZNF212

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF212 Gene

Disorders for ZNF212 Gene

Relevant External Links for ZNF212

Genetic Association Database (GAD)
ZNF212
genes like me logo Genes that share disorders with ZNF212: view

No data available for UniProtKB/Swiss-Prot for ZNF212 Gene

Publications for ZNF212 Gene

  1. Molecular cloning and mapping of a novel human KRAB domain-containing C2H2-type zinc finger to chromosome 7q36.1. (PMID: 9169157) Becker K.G. … Drew P.D. (Genomics 1997) 2 3 4
  2. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. (PMID: 7633419) Becker K.G. … Drew P.D. (Hum. Mol. Genet. 1995) 3 4
  5. A protein-protein interaction network of transcription factors acting during liver cell proliferation. (PMID: 18255255) Gao J. … Yu Y. (Genomics 2008) 3

Products for ZNF212 Gene

Sources for ZNF212 Gene

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