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Aliases for ZNF211 Gene

Aliases for ZNF211 Gene

  • Zinc Finger Protein 211 2 3 5
  • Zinc Finger Protein C2H2-25 3 4
  • CH2H2-25 3
  • C2H2-25 3
  • ZNF-25 3

External Ids for ZNF211 Gene

Previous GeneCards Identifiers for ZNF211 Gene

  • GC19P059043
  • GC19P058598
  • GC19P062820
  • GC19P062836
  • GC19P058141
  • GC19P054456

Summaries for ZNF211 Gene

Entrez Gene Summary for ZNF211 Gene

  • This gene encodes a protein containing a Kruppel-associated box domain and multiple zinc finger domains. This protein may play a role in developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

GeneCards Summary for ZNF211 Gene

ZNF211 (Zinc Finger Protein 211) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF256.

UniProtKB/Swiss-Prot for ZNF211 Gene

  • May be involved in transcriptional regulation.

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF211 Gene

Genomics for ZNF211 Gene

Regulatory Elements for ZNF211 Gene

Enhancers for ZNF211 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G057599 1.1 ENCODE 33.5 -30.4 -30358 1.5 PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF207 ZNF143 SP3 ZHX2 ZNF606 ZNF549 ZNF417 ZNF418 LOC100128398 ZNF17 ZNF773 LOC105372482 ZNF211 ENSG00000268201
GH19G057809 1.7 FANTOM5 ENCODE dbSUPER 18.2 +182.8 182823 7.2 CREB3L1 MLX ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 ZNF134 ZNF264 TRIM28 ZNF17 ZNF417 ZNF256 ZNF543 ZNF805 ZNF606 ZNF773
GH19G057650 1.1 Ensembl ENCODE 24.2 +21.5 21481 2.3 DRAP1 CTCF TFAP4 ESRRA KLF1 SAP130 TBL1XR1 RAD21 ZNF791 POLR2A ZNF211 ZNF134 ZNF548 ZNF550 ZNF417 ZNF551 ZNF264 ZNF671 RPS5 TRIM28
GH19G057632 1 ENCODE 18.4 +3.0 3022 1.8 PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF207 ZNF143 FOS ZNF548 ZNF264 ZNF550 TRIM28 ZNF134 ZNF211 ZNF805 ZNF417 ZNF551 ZNF549
GH19G057239 1.1 ENCODE 16.3 -389.2 -389247 2.6 PKNOX1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 ZNF264 ZNF134 ZNF543 ZNF551 ZNF211 ZNF805 AURKC ZNF606 ZNF471 ZNF549
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF211 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF211 Gene

Chromosome:
19
Start:
57,630,395 bp from pter
End:
57,642,779 bp from pter
Size:
12,385 bases
Orientation:
Plus strand

Genomic View for ZNF211 Gene

Genes around ZNF211 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF211 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF211 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF211 Gene

Proteins for ZNF211 Gene

  • Protein details for ZNF211 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13398-ZN211_HUMAN
    Recommended name:
    Zinc finger protein 211
    Protein Accession:
    Q13398
    Secondary Accessions:
    • B4DH10
    • B4DLC9
    • B4E3C9
    • B9ZVS7
    • B9ZVW1
    • F8WDV2
    • Q05BQ7
    • Q2TAL7
    • Q59EG4
    • Q59G36
    • Q5EBL6

    Protein attributes for ZNF211 Gene

    Size:
    564 amino acids
    Molecular mass:
    64535 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAA93261.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH34351.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAD93084.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF211 Gene

neXtProt entry for ZNF211 Gene

Post-translational modifications for ZNF211 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF211 Gene

Domains & Families for ZNF211 Gene

Gene Families for ZNF211 Gene

Suggested Antigen Peptide Sequences for ZNF211 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13398

UniProtKB/Swiss-Prot:

ZN211_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF211: view

Function for ZNF211 Gene

Molecular function for ZNF211 Gene

GENATLAS Biochemistry:
zinc finger protein 211,C2H2 type,expressed in the brain
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF211 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF211: view
genes like me logo Genes that share phenotypes with ZNF211: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF211 Gene

Localization for ZNF211 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF211 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF211 gene
Compartment Confidence
nucleus 5
mitochondrion 2
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF211 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF211: view

Pathways & Interactions for ZNF211 Gene

SuperPathways for ZNF211 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF211: view

Pathways by source for ZNF211 Gene

2 Reactome pathways for ZNF211 Gene

Gene Ontology (GO) - Biological Process for ZNF211 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF211: view

No data available for SIGNOR curated interactions for ZNF211 Gene

Transcripts for ZNF211 Gene

Unigene Clusters for ZNF211 Gene

Zinc finger protein 211:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF211 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: - -
SP2: -
SP3: - - - - -
SP4: - - - - - - - - - -
SP5: - - - - - -
SP6: - -
SP7:
SP8: - -

Relevant External Links for ZNF211 Gene

GeneLoc Exon Structure for
ZNF211
ECgene alternative splicing isoforms for
ZNF211

Expression for ZNF211 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF211 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF211 Gene:

ZNF211

SOURCE GeneReport for Unigene cluster for ZNF211 Gene:

Hs.590977

Evidence on tissue expression from TISSUES for ZNF211 Gene

  • Heart(4.2)
  • Skin(4.2)
  • Nervous system(4.2)
  • Blood(4)
genes like me logo Genes that share expression patterns with ZNF211: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF211 Gene

Orthologs for ZNF211 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF211 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF211 34 35
  • 98.92 (n)
dog
(Canis familiaris)
Mammalia ZNF211 34 35
  • 84.24 (n)
cow
(Bos Taurus)
Mammalia LOC789996 34
  • 83.48 (n)
ZNF211 35
  • 78 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta Cf2 36
  • 48 (a)
CG3407 36
  • 40 (a)
CG8319 36
  • 36 (a)
CG6689 36
  • 30 (a)
Species where no ortholog for ZNF211 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF211 Gene

ENSEMBL:
Gene Tree for ZNF211 (if available)
TreeFam:
Gene Tree for ZNF211 (if available)

Paralogs for ZNF211 Gene

(551) SIMAP similar genes for ZNF211 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF211 Gene

genes like me logo Genes that share paralogs with ZNF211: view

Variants for ZNF211 Gene

Sequence variations from dbSNP and Humsavar for ZNF211 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000082868 -- 57,638,804(+) TTGAT(A/G)TCTCT intron-variant
rs1000117549 -- 57,635,062(+) CTAAC(A/G)TTTAT intron-variant
rs1000152828 -- 57,631,777(+) TGGGC(C/T)CTATA upstream-variant-2KB
rs1000261229 -- 57,632,752(+) GGAAG(C/T)GGATC upstream-variant-2KB
rs1000702944 -- 57,640,432(+) AAAAG(C/T)TATTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF211 Gene

Variant ID Type Subtype PubMed ID
dgv3685n100 CNV gain 25217958
esv3575120 CNV gain 25503493
nsv580402 CNV gain 21841781

Variation tolerance for ZNF211 Gene

Residual Variation Intolerance Score: 63.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.02; 87.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF211 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF211

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF211 Gene

Disorders for ZNF211 Gene

Relevant External Links for ZNF211

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF211

No disorders were found for ZNF211 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF211 Gene

Publications for ZNF211 Gene

  1. Molecular cloning and mapping of a novel developmentally regulated human C2H2-type zinc finger. (PMID: 9096115) Becker K.G. … Drew P.D. (Mamm. Genome 1997) 2 3 4 64
  2. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. (PMID: 7633419) Becker K.G. … Drew P.D. (Hum. Mol. Genet. 1995) 2 3 4 64
  3. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PMID: 17043677) Camargo L.M. … Brandon N.J. (Mol. Psychiatry 2007) 3 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64

Products for ZNF211 Gene

Sources for ZNF211 Gene

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