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Aliases for ZNF205 Gene

Aliases for ZNF205 Gene

  • Zinc Finger Protein 205 2 3
  • ZNF210 3 4 6
  • Zinc Finger Protein 210 3 4
  • Transcriptional Repressor RhitH 3
  • RhitH 3
  • Zfp13 3

External Ids for ZNF205 Gene

Previous HGNC Symbols for ZNF205 Gene

  • ZNF210

Previous GeneCards Identifiers for ZNF205 Gene

  • GC16P003183
  • GC16P003162
  • GC16P003104
  • GC16P003105
  • GC16P003133

Summaries for ZNF205 Gene

GeneCards Summary for ZNF205 Gene

ZNF205 (Zinc Finger Protein 205) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression.

UniProtKB/Swiss-Prot for ZNF205 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF205 Gene

Genomics for ZNF205 Gene

Regulatory Elements for ZNF205 Gene

Genomic Location for ZNF205 Gene

Start:
3,112,560 bp from pter
End:
3,120,527 bp from pter
Size:
7,968 bases
Orientation:
Plus strand

Genomic View for ZNF205 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF205 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF205 Gene

Proteins for ZNF205 Gene

  • Protein details for ZNF205 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95201-ZN205_HUMAN
    Recommended name:
    Zinc finger protein 205
    Protein Accession:
    O95201
    Secondary Accessions:
    • A8MZK0
    • D3DUB4
    • Q9BU95

    Protein attributes for ZNF205 Gene

    Size:
    554 amino acids
    Molecular mass:
    60630 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC70007.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF205 Gene

Proteomics data for ZNF205 Gene at MOPED

Post-translational modifications for ZNF205 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF205 Gene

No data available for DME Specific Peptides for ZNF205 Gene

Domains for ZNF205 Gene

Gene Families for ZNF205 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF205 Gene

Suggested Antigen Peptide Sequences for ZNF205 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O95201

UniProtKB/Swiss-Prot:

ZN205_HUMAN :
  • O95201
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF205: view

Function for ZNF205 Gene

Molecular function for ZNF205 Gene

GENATLAS Biochemistry: zinc finger protein 205,C2H2 type,with an alternative transcript ZNF210,ubiquitously expressed
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF205 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 16713569
GO:0008270 zinc ion binding NAS 9787081
genes like me logo Genes that share ontologies with ZNF205: view

Phenotypes for ZNF205 Gene

MGI mutant phenotypes for ZNF205:
inferred from 1 alleles
GenomeRNAi human phenotypes for ZNF205:
genes like me logo Genes that share phenotypes with ZNF205: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF205 Gene

Localization for ZNF205 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF205 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF205 Gene COMPARTMENTS Subcellular localization image for ZNF205 gene
Compartment Confidence
nucleus 5
cytosol 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF205 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF205: view

Pathways for ZNF205 Gene

SuperPathways for ZNF205 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF205: view

Pathways by source for ZNF205 Gene

2 Reactome pathways for ZNF205 Gene

Gene Ontology (GO) - Biological Process for ZNF205 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IMP 22306510
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS 9787081
GO:0010729 positive regulation of hydrogen peroxide biosynthetic process IMP 22306510
GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IMP 22306510
genes like me logo Genes that share ontologies with ZNF205: view

Transcripts for ZNF205 Gene

Unigene Clusters for ZNF205 Gene

Zinc finger protein 205:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF205 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b
SP1: - -
SP2: - - -
SP3: -
SP4: - - -
SP5:

Relevant External Links for ZNF205 Gene

GeneLoc Exon Structure for
ZNF205
ECgene alternative splicing isoforms for
ZNF205

Expression for ZNF205 Gene

mRNA expression in normal human tissues for ZNF205 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF205 Gene Hs.592088

mRNA Expression by UniProt/SwissProt for ZNF205 Gene

O95201-ZN205_HUMAN
Tissue specificity: Expressed in heart, skeletal muscle, pancreas and brain. Weakly expressed in placenta, lung, liver, kidney and thymus
genes like me logo Genes that share expressions with ZNF205: view

No data available for mRNA differential expression in normal tissues and Protein expression for ZNF205 Gene

Orthologs for ZNF205 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF205 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF205 35
  • 98.92 (n)
  • 98.92 (a)
ZNF205 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF205 35
  • 84.52 (n)
  • 78.51 (a)
ZNF205 36
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF205 35
  • 83.8 (n)
  • 78.91 (a)
ZNF205 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp13 35
  • 79.39 (n)
  • 74.9 (a)
Zfp13 16
Zfp13 36
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp13 35
  • 81.76 (n)
  • 80.24 (a)
Species with no ortholog for ZNF205:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF205 Gene

ENSEMBL:
Gene Tree for ZNF205 (if available)
TreeFam:
Gene Tree for ZNF205 (if available)

Paralogs for ZNF205 Gene

Selected SIMAP similar genes for ZNF205 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF205: view

No data available for Paralogs for ZNF205 Gene

Variants for ZNF205 Gene

Sequence variations from dbSNP and Humsavar for ZNF205 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs12032 -- 3,120,187(+) TTGTG(C/T)GGCAA reference, synonymous-codon
rs224179 -- 3,118,066(+) accat(C/G)ttggc intron-variant
rs224180 -- 3,118,724(+) CAGCT(C/T)TGGCA intron-variant
rs224181 -- 3,118,835(+) AGTTT(A/G/T)GGGGA intron-variant
rs9922546 -- 3,117,794(+) GTTTT(A/C)ATACG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF205 Gene

Variant ID Type Subtype PubMed ID
nsv905170 CNV Loss 21882294
nsv905185 CNV Loss 21882294
nsv833125 CNV Loss 17160897
nsv509589 CNV Insertion 20534489
dgv2580n71 CNV Loss 21882294
nsv457355 CNV Gain 19166990

Relevant External Links for ZNF205 Gene

HapMap Linkage Disequilibrium report
ZNF205

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF205 Gene

Disorders for ZNF205 Gene

(1) University of Copenhagen DISEASES for ZNF205 Gene

genes like me logo Genes that share disorders with ZNF205: view

No data available for UniProtKB/Swiss-Prot for ZNF205 Gene

Publications for ZNF205 Gene

  1. Identification of two Kruppel-related zinc finger genes (ZNF200 and ZNF210) from human chromosome 16p13.3. (PMID: 9787081) Deng Z. … Kastner D.L. (Genomics 1998) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PMID: 16712791) Wang A.G. … Kim N.S. (Biochem. Biophys. Res. Commun. 2006) 3
  5. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PMID: 16713569) Lim J. … Zoghbi H.Y. (Cell 2006) 3

Products for ZNF205 Gene

Sources for ZNF205 Gene

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