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Aliases for ZNF200 Gene

Aliases for ZNF200 Gene

  • Zinc Finger Protein 200 2 3
  • ZNFMF 4

External Ids for ZNF200 Gene

Previous GeneCards Identifiers for ZNF200 Gene

  • GC16M003292
  • GC16M003272
  • GC16M003212

Summaries for ZNF200 Gene

GeneCards Summary for ZNF200 Gene

ZNF200 (Zinc Finger Protein 200) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF597.

UniProtKB/Swiss-Prot for ZNF200 Gene

  • Could have a role in spermatogenesis

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF200 Gene

Genomics for ZNF200 Gene

Regulatory Elements for ZNF200 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF200 Gene

Start:
3,222,325 bp from pter
End:
3,236,221 bp from pter
Size:
13,897 bases
Orientation:
Minus strand

Genomic View for ZNF200 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF200 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF200 Gene

Proteins for ZNF200 Gene

  • Protein details for ZNF200 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P98182-ZN200_HUMAN
    Recommended name:
    Zinc finger protein 200
    Protein Accession:
    P98182
    Secondary Accessions:
    • D3DUB7
    • D3DUB8
    • O15361
    • Q5XKM5
    • Q7Z5V1

    Protein attributes for ZNF200 Gene

    Size:
    395 amino acids
    Molecular mass:
    45534 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC70008.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH54005.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF200 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF200 Gene

Proteomics data for ZNF200 Gene at MOPED

Post-translational modifications for ZNF200 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF200 Gene

Domains for ZNF200 Gene

Gene Families for ZNF200 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF200 Gene

Graphical View of Domain Structure for InterPro Entry

P98182

UniProtKB/Swiss-Prot:

ZN200_HUMAN :
  • P98182
Similarity:
  • Contains 5 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF200: view

Function for ZNF200 Gene

Molecular function for ZNF200 Gene

GENATLAS Biochemistry: zinc finger protein 200,C2H2 type,predominantly expressed in testis
UniProtKB/Swiss-Prot Function: Could have a role in spermatogenesis

Gene Ontology (GO) - Molecular Function for ZNF200 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF200: view

Phenotypes for ZNF200 Gene

GenomeRNAi human phenotypes for ZNF200:
genes like me logo Genes that share phenotypes with ZNF200: view

Animal Model Products

CRISPR Products

miRNA for ZNF200 Gene

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF200

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF200 Gene

Localization for ZNF200 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF200 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF200 Gene COMPARTMENTS Subcellular localization image for ZNF200 gene
Compartment Confidence
nucleus 5
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ZNF200 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF200: view

Pathways for ZNF200 Gene

SuperPathways for ZNF200 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF200: view

Pathways by source for ZNF200 Gene

2 Reactome pathways for ZNF200 Gene

Gene Ontology (GO) - Biological Process for ZNF200 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF200: view

Transcripts for ZNF200 Gene

Unigene Clusters for ZNF200 Gene

Zinc finger protein 200:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF200

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF200 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
SP1: - - -
SP2: - - -
SP3: -
SP4: -
SP5: - -
SP6: - - - -
SP7:

Relevant External Links for ZNF200 Gene

GeneLoc Exon Structure for
ZNF200
ECgene alternative splicing isoforms for
ZNF200

Expression for ZNF200 Gene

mRNA expression in normal human tissues for ZNF200 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF200 Gene

This gene is overexpressed in Testis (5.1) and Whole Blood (4.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF200 Gene

SOURCE GeneReport for Unigene cluster for ZNF200 Gene Hs.632222

mRNA Expression by UniProt/SwissProt for ZNF200 Gene

P98182-ZN200_HUMAN
Tissue specificity: Highly expressed in testis, weakly expressed in spleen, thymus, prostate, ovary, small intestine colon and peripheral blood leukocytes
genes like me logo Genes that share expressions with ZNF200: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for ZNF200 Gene

Orthologs for ZNF200 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF200 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF200 35
  • 99.41 (n)
  • 98.98 (a)
ZNF200 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF200 35
  • 88.01 (n)
  • 86.73 (a)
ZNF200 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF200 35
  • 87.44 (n)
  • 83.33 (a)
ZNF200 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF200 36
  • 57 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii CR352258.1 36
  • 35 (a)
OneToMany
Species with no ortholog for ZNF200:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF200 Gene

ENSEMBL:
Gene Tree for ZNF200 (if available)
TreeFam:
Gene Tree for ZNF200 (if available)

Paralogs for ZNF200 Gene

Paralogs for ZNF200 Gene

genes like me logo Genes that share paralogs with ZNF200: view

Variants for ZNF200 Gene

Sequence variations from dbSNP and Humsavar for ZNF200 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs11228 -- 3,222,391(+) ACCAA(C/G)AAACT utr-variant-3-prime
rs224235 -- 3,226,444(+) CAAAA(A/G)CAGCT intron-variant
rs224236 -- 3,227,298(+) tttga(A/G)tctta intron-variant
rs401298 -- 3,230,974(+) GGAAG(A/G)TTACA intron-variant
rs442387 -- 3,236,118(+) GCCCA(C/T)TCCAG upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF200 Gene

Variant ID Type Subtype PubMed ID
nsv457355 CNV Gain 19166990
nsv905208 CNV Loss 21882294
nsv833127 CNV Gain+Loss 17160897
nsv471074 CNV Gain 18288195
nsv905209 CNV Gain 21882294
nsv516280 CNV Gain 19592680
nsv509592 CNV Insertion 20534489
dgv2583n71 CNV Loss 21882294

Relevant External Links for ZNF200 Gene

HapMap Linkage Disequilibrium report
ZNF200

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF200 Gene

Disorders for ZNF200 Gene

No disorders were found for ZNF200 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF200 Gene

Publications for ZNF200 Gene

  1. Identification of two Kruppel-related zinc finger genes (ZNF200 and ZNF210) from human chromosome 16p13.3. (PMID: 9787081) Deng Z. … Kastner D.L. (Genomics 1998) 2 3 4
  2. A candidate gene for familial Mediterranean fever. (PMID: 9288094) Bernot A. … Grateau G. (Nat. Genet. 1997) 2 3 4
  3. A transcriptional map of the FMF region. (PMID: 9653642) Bernot A. … Weissenbach J. (Genomics 1998) 3
  4. Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library. (PMID: 8401585) Adams M.D. … Venter J.C. (Nat. Genet. 1993) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF200 Gene

Sources for ZNF200 Gene

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