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Aliases for ZNF20 Gene

Aliases for ZNF20 Gene

  • Zinc Finger Protein 20 2 3
  • KOX13 3 4 6
  • Zinc Finger Protein KOX13 3 4
  • Zinc Finger Protein 20 (KOX 13) 2

External Ids for ZNF20 Gene

Previous GeneCards Identifiers for ZNF20 Gene

  • GC19M012374
  • GC19M012465
  • GC19M012089
  • GC19M012241
  • GC19M011818

Summaries for ZNF20 Gene

GeneCards Summary for ZNF20 Gene

ZNF20 (Zinc Finger Protein 20) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF20 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF20 Gene

Genomics for ZNF20 Gene

Regulatory Elements for ZNF20 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF20 Gene

Start:
12,092,843 bp from pter
End:
12,140,407 bp from pter
Size:
47,565 bases
Orientation:
Minus strand

Genomic View for ZNF20 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF20 Gene

Proteins for ZNF20 Gene

  • Protein details for ZNF20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17024-ZNF20_HUMAN
    Recommended name:
    Zinc finger protein 20
    Protein Accession:
    P17024
    Secondary Accessions:
    • Q8N457
    • Q9UG41

    Protein attributes for ZNF20 Gene

    Size:
    532 amino acids
    Molecular mass:
    61567 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF20 Gene

Proteomics data for ZNF20 Gene at MOPED

Post-translational modifications for ZNF20 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF20 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF20 Gene

Domains for ZNF20 Gene

Gene Families for ZNF20 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF20 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17024

UniProtKB/Swiss-Prot:

ZNF20_HUMAN :
  • P17024
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF20: view

Function for ZNF20 Gene

Molecular function for ZNF20 Gene

GENATLAS Biochemistry: zinc finger protein 20 (KOX13) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF20: view

Animal Model Products

CRISPR Products

miRNA for ZNF20 Gene

miRTarBase miRNAs that target ZNF20

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF20

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF20 Gene

Localization for ZNF20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF20 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF20 Gene COMPARTMENTS Subcellular localization image for ZNF20 gene
Compartment Confidence
nucleus 3
cytosol 2
plasma membrane 1

Gene Ontology (GO) - Cellular Components for ZNF20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF20: view

Pathways for ZNF20 Gene

SuperPathways for ZNF20 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF20: view

Pathways by source for ZNF20 Gene

2 Reactome pathways for ZNF20 Gene

Gene Ontology (GO) - Biological Process for ZNF20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF20: view

Transcripts for ZNF20 Gene

Unigene Clusters for ZNF20 Gene

Zinc finger protein 20:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF20

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF20
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF20 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12a · 12b · 12c · 12d
SP1: - - - - - - - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - - - -
SP5: - - - - -
SP6:
SP7: - -
SP8: -
SP9: - - - -

Relevant External Links for ZNF20 Gene

GeneLoc Exon Structure for
ZNF20
ECgene alternative splicing isoforms for
ZNF20

Expression for ZNF20 Gene

mRNA expression in normal human tissues for ZNF20 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF20 Gene

This gene is overexpressed in Testis (13.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF20 Gene

SOURCE GeneReport for Unigene cluster for ZNF20 Gene Hs.512823

genes like me logo Genes that share expressions with ZNF20: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ZNF20 Gene

Orthologs for ZNF20 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF20 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF20 35
  • 99.75 (n)
  • 99.24 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 50 (a)
ManyToMany
Species with no ortholog for ZNF20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF20 Gene

ENSEMBL:
Gene Tree for ZNF20 (if available)
TreeFam:
Gene Tree for ZNF20 (if available)

Paralogs for ZNF20 Gene

Selected SIMAP similar genes for ZNF20 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF20 Gene

genes like me logo Genes that share paralogs with ZNF20: view

Variants for ZNF20 Gene

Structural Variations from Database of Genomic Variants (DGV) for ZNF20 Gene

Variant ID Type Subtype PubMed ID
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294
nsv833753 CNV Loss 17160897
esv2665806 CNV Deletion 23128226

Relevant External Links for ZNF20 Gene

HapMap Linkage Disequilibrium report
ZNF20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for ZNF20 Gene

Disorders for ZNF20 Gene

No disorders were found for ZNF20 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF20 Gene

Publications for ZNF20 Gene

  1. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  2. Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19. (PMID: 8262519) Rousseau-Merck M.F. … Berger R. (Hum. Genet. 1993) 3
  3. The zinc finger-associated SCAN box is a conserved oligomerization domain. (PMID: 10567577) Williams A.J. … Collins T. (Mol. Cell. Biol. 1999) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with zinc finger gene clusters predominantly in 23 chromosomal loci are confirmed by human sequences annotated in EnsEMBL. (PMID: 12697996) Rousseau-Merck M.F. … Thiesen H.J. (Cytogenet. Genome Res. 2002) 3

Products for ZNF20 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF20
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF20
    • Block miRNA regulation of ZNF20 using miScript Target Protectors

    Sources for ZNF20 Gene

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