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ZNF197 Gene

protein-coding   GIFtS: 52
GCID: GC03P044783

Zinc Finger Protein 197

(Previous name: zinc finger protein 166)
(Previous symbol: ZNF166)
Microbiology & Infectious Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 1971 2     P182
ZNF1661 2 3     VHLaK2
Zinc Finger Protein 1661 2     ZNF202
Zinc Finger Protein With KRAB And SCAN Domains 92 3     ZSCAN412
ZKSCAN92 3     VHL-Associated KRAB-A Domain-Containing Protein2
PVHL-Associated KRAB Domain-Containing Protein2 3     Zinc Finger Protein 202
D3S1363E2     ZnF203

External Ids:    HGNC: 129881   Entrez Gene: 101682   Ensembl: ENSG000001864487   UniProtKB: O147093   

Export aliases for ZNF197 gene to outside databases

Previous GC identifers: GC03P044135 GC03P043850 GC03P044416 GC03P044631 GC03P044558 GC03P044645 GC03P044674 GC03P044688 GC03P044716


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ZNF197 Gene:
This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins
characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed
C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over
rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in
some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two
alternatively spliced transcripts encoding different isoforms have been described. (provided by RefSeq, Jul 2008)

GeneCards Summary for ZNF197 Gene:
ZNF197 (zinc finger protein 197) is a protein-coding gene. Diseases associated with ZNF197 include papillary carcinoma, and subacute sclerosing panencephalitis. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF616.

UniProtKB/Swiss-Prot: ZN197_HUMAN, O14709
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF197 gene promoter:
         ZID   MIF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF197 promoter sequence
   Search Chromatin IP Primers for ZNF197

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF197


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21

ZNF197 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF197 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P044783:  view genomic region     (about GC identifiers)

Start:
44,626,380 bp from pter      End:
44,689,963 bp from pter
Size:
63,584 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZN197_HUMAN, O14709 (See protein sequence)
Recommended Name: Zinc finger protein 197  
Size: 1029 amino acids; 118847 Da
Secondary accessions: B2RAH8 Q86VG0
Alternative splicing: 2 isoforms:  O14709-1   O14709-2   (Negative regulator of HIF1A transactivation)

Explore the universe of human proteins at neXtProt for ZNF197: NX_O14709

Explore proteomics data for ZNF197 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF197 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001020026.1  NP_008922.1  

    ENSEMBL proteins: 
     ENSP00000394713   ENSP00000373250   ENSP00000345809   ENSP00000373251   ENSP00000334616  
     ENSP00000379370  
    Reactome Protein details: O14709

    ZNF197 Human Recombinant Protein Products:

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    Novus Biologicals ZNF197 Protein
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    Cloud-Clone Corp. Proteins for ZNF197

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    Cloud-Clone Corp. CLIAs for ZNF197


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 6):
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd

    Graphical View of Domain Structure for InterPro Entry O14709

    ProtoNet protein and cluster: O14709

    3 Blocks protein domains:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN197_HUMAN, O14709
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 22 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain
    Similarity: Contains 1 SCAN box domain


    ZNF197 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN197_HUMAN, O14709
    Function: May be involved in transcriptional regulation

         Genatlas biochemistry entry for ZNF197:
    zinc finger protein 197

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IBA--
    GO:0046872metal ion binding IEA--
         
    ZNF197 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for ZNF197:
     Decreased POU5F1-GFP protein e  Decreased viability of wild-ty  G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF197
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF197
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF197

    miRNA
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    Block miRNA regulation of human, mouse, rat ZNF197 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZNF197 (see all 25):
    hsa-miR-30c hsa-miR-549 hsa-miR-676 hsa-let-7d hsa-miR-30d hsa-let-7c hsa-miR-138-2* hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidZNF197 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ZNF197
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF197

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for ZNF197

    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): ZNF197 (NM_001024855)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF197
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF197

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ZNF197 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF197


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN197_HUMAN, O14709: Nucleus (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    ZNF197 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF197 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF197
        Generic Transcription Pathway



    ZNF197 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF197
    Interactions:

        GeneGlobe Interaction Network for ZNF197

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for ZNF197 (O147093 ENSP000003458094) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DISC1Q9NRI53, ENSP000003555964I2D: score=2 STRING: ENSP00000355596
    NDEL1Q9GZM83, ENSP000003339824I2D: score=2 STRING: ENSP00000333982
    TRIM28Q132633, ENSP000002530244I2D: score=2 STRING: ENSP00000253024
    HIF1AQ166653, ENSP000003380184I2D: score=1 STRING: ENSP00000338018
    VHLP403373, ENSP000002564744I2D: score=2 STRING: ENSP00000256474
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IBA--

    ZNF197 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF197 (ZN197)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ZNF197 gene (2 alternative transcripts): 
    NM_001024855.1  NM_006991.3  

    Unigene Cluster for ZNF197:

    Zinc finger protein 197
    Hs.157035  [show with all ESTs]
    Unigene Representative Sequence: NM_006991
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000412641 ENST00000383744 ENST00000344387 ENST00000383745(uc003cnn.3 uc003cno.3 uc003cnp.3)
    ENST00000334075 ENST00000396058(uc003cnm.3)
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ZNF197 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ZNF197 (see all 25):
    hsa-miR-30c hsa-miR-549 hsa-miR-676 hsa-let-7d hsa-miR-30d hsa-let-7c hsa-miR-138-2* hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidZNF197 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ZNF197
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF197
    Clone
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    OriGene clones in human, mouse for ZNF197 (see all 9)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ZNF197 (NM_001024855)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF197
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF197
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF197
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF197
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF197
      QuantiFast Probe-based Assays in human, mouse, rat ZNF197

    Additional mRNA sequence: 

    AF011573.1 AK314196.1 AL117657.1 AY074878.1 AY261677.1 AY279353.1 BC017584.1 BC031209.1 
    L32163.1 Z21707.1 

    8 DOTS entries:

    DT.87015004  DT.101974543  DT.92421579  DT.95241240  DT.40223028  DT.120928274  DT.95361407  DT.92062677 

    Selected AceView cDNA sequences (see all 94):

    AI341305 AY261677 BG170556 BX955582 BU184659 AI491958 CR610755 AI693874 
    AI091827 AI333785 NM_006991 AF011573 CF138878 AA385151 AL555231 AL134897 
    BQ002665 BF477932 CR624024 BQ018704 BP336356 BP336662 AU125702 AL577777 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF197    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6
    SP1:                                                
    SP2:              -                                 


    ECgene alternative splicing isoforms for ZNF197

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF197 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZNF197 Expression
    About this image

    ZNF197 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF197 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.157035
        Custom PCR Arrays for ZNF197
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF197

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ZNF197 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.49002 Transcribed sequence with weak similarity to protein more 72.56(n)    142031492 
            Species with no ortholog for ZNF197

    ENSEMBL Gene Tree for ZNF197 (if available)
    TreeFam Gene Tree for ZNF197 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF197 gene
    ZNF6162  ZNF4732  ZNF1602  ZNF4932  ZNF5462  ZNF992  ZNF8362  ZNF7212  
    ZNF5942  ZFP622  ZNF8412  ZNF432  ZNF780B2  ZNF1072  ZNF585A2  ZNF8082  
    ZNF3472  ZNF8452  ZNF585B2  ZNF6582  ZNF6292  ZNF6242  ZNF2682  ZNF8142  
    Selected SIMAP similar genes for ZNF197 using alignment to 4 protein entries:     ZN197_HUMAN (see all proteins) (see all similar genes):
    ZNF446    ZSCAN29    SCAND1    ZSCAN18    MZF1    ZSCAN21
    ZSCAN2    ZNF396    ZNF444    ZNF500    DKFZp434K202    ZNF394
    DKFZp686B16128    ZFS-1    ZSCAN32    LOC100128510    ZNF101    ZNF345

    ZNF197 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF197 (see all 472)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1857341531,2
    --44664596(+) GGTGGC/TGTGCG 2 -- us2k10--------
    rs1436545071,2
    C--44664664(+) CGGAGA/GTTGCA 2 -- us2k10--------
    rs1124603111,2
    C--44664706(+) TGGGCG/AACAGA 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1480977711,2
    C--44664714(+) AGAGTG/TAGACT 2 -- us2k10--------
    rs1902724161,2
    --44664797(+) AAACTC/TGGAGA 2 -- us2k10--------
    rs1810909411,2
    --44665084(+) CCTGGA/TGCAAT 2 -- us2k10--------
    rs1865345751,2
    --44665155(+) AAAAAC/TGACCC 2 -- us2k10--------
    rs1913439321,2
    --44665170(+) CTTATC/GATCAG 2 -- us2k10--------
    rs1822041121,2
    --44665180(+) GCTTTA/CACATT 2 -- us2k10--------
    rs1410896581,2
    C--44665201(+) TACCAC/TCACCT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for ZNF197 (44626380 - 44689963 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZNF197: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF197
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF197

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    6 diseases for ZNF197:    
    About MalaCards
    papillary carcinoma    subacute sclerosing panencephalitis    thyroiditis    measles
    thyroid cancer    schizophrenia


    ZNF197 for disorders           About GeneDecksing


    Export disorders for ZNF197 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF197 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZNF197)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of rapid turnover transcripts overexpressed in thyroid tumors and thyroid cancer cell lines: use of a targeted differential RNA display method to select for mRNA subsets. (PubMed id 9380504)1, 2, 3, 9 Gonsky R.... Fagin J.A. (Nucleic Acids Res. 1997)
    2. The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity. (PubMed id 12682018)1, 2, 9 Li Z.... Wu G. (EMBO J. 2003)
    3. YAC-assisted cloning of transcribed sequences from the human chromosome 3p21 region. (PubMed id 8353497)1, 3 Pengue G.... D'Urso M. (Hum. Mol. Genet. 1993)
    4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    5. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)1 Camargo L.M....Brandon N.J. (Mol. Psychiatry 2007)
    6. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Positional cloning of cDNAs from the human chromosome 3p21-22 region identifies a clustered organization of zinc-finger genes. (PubMed id 7814019)1 CalabrA^ V....Lania L. (Hum. Genet. 1995)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10168 HGNC: 12988 AceView: ZNF197 Ensembl:ENSG00000186448 euGenes: HUgn10168
    ECgene: ZNF197 H-InvDB: ZNF197

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF197 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ZNF197 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF197 gene:
    Search GeneIP for patents involving ZNF197

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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