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Aliases for ZNF19 Gene

Aliases for ZNF19 Gene

  • Zinc Finger Protein 19 2 3
  • KOX12 3 4 6
  • Zinc Finger Protein 19 (KOX 12) 2 3
  • Zinc Finger Protein KOX12 3 4

External Ids for ZNF19 Gene

Previous GeneCards Identifiers for ZNF19 Gene

  • GC16U990061
  • GC16M072231
  • GC16M071217
  • GC16M071284
  • GC16M070065
  • GC16M057276

Summaries for ZNF19 Gene

Entrez Gene Summary for ZNF19 Gene

  • The protein encoded by this gene contains a zinc finger, a nucleic acid-binding domain present in many transcription factors. This gene is located in a region next to ZNF23, a gene also encoding a zinc finger protein, on chromosome 16. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF19 Gene

ZNF19 (Zinc Finger Protein 19) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF662.

UniProtKB/Swiss-Prot for ZNF19 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF19 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF19 Gene

Genomics for ZNF19 Gene

Regulatory Elements for ZNF19 Gene

Genomic Location for ZNF19 Gene

Start:
71,464,555 bp from pter
End:
71,565,089 bp from pter
Size:
100,535 bases
Orientation:
Minus strand

Genomic View for ZNF19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF19 Gene

Proteins for ZNF19 Gene

  • Protein details for ZNF19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17023-ZNF19_HUMAN
    Recommended name:
    Zinc finger protein 19
    Protein Accession:
    P17023
    Secondary Accessions:
    • A8K895
    • Q86Y66
    • Q8NDE2
    • Q96M79
    • Q96NE5

    Protein attributes for ZNF19 Gene

    Size:
    458 amino acids
    Molecular mass:
    52449 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAA36814.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF19 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF19 Gene

Proteomics data for ZNF19 Gene at MOPED

Post-translational modifications for ZNF19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF19 Gene

Domains for ZNF19 Gene

Gene Families for ZNF19 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P17023

UniProtKB/Swiss-Prot:

ZNF19_HUMAN :
  • P17023
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF19: view

Function for ZNF19 Gene

Molecular function for ZNF19 Gene

GENATLAS Biochemistry: zinc finger protein 19 (KOX12) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity NAS 7557990
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF19: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF19 Gene

Localization for ZNF19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF19 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF19 Gene COMPARTMENTS Subcellular localization image for ZNF19 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus NAS 7557990
genes like me logo Genes that share ontologies with ZNF19: view

Pathways for ZNF19 Gene

SuperPathways for ZNF19 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF19: view

Pathways by source for ZNF19 Gene

2 Reactome pathways for ZNF19 Gene

Interacting Proteins for ZNF19 Gene

Gene Ontology (GO) - Biological Process for ZNF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS 7557990
genes like me logo Genes that share ontologies with ZNF19: view

Transcripts for ZNF19 Gene

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF19

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF19
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF19 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c
SP1: - - -
SP2: - - - -
SP3:
SP4: -
SP5: - -
SP6: -

Relevant External Links for ZNF19 Gene

GeneLoc Exon Structure for
ZNF19
ECgene alternative splicing isoforms for
ZNF19

Expression for ZNF19 Gene

mRNA expression in normal human tissues for ZNF19 Gene

genes like me logo Genes that share expressions with ZNF19: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF19 Gene

Orthologs for ZNF19 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF19 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToMany
ZNF19 35
  • 99.34 (n)
  • 98.69 (a)
cow
(Bos Taurus)
Mammalia ZNF19 35
  • 84.62 (n)
  • 79.69 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 85 (a)
OneToMany
ZNF19 35
  • 87.82 (n)
  • 82.71 (a)
Species with no ortholog for ZNF19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF19 Gene

ENSEMBL:
Gene Tree for ZNF19 (if available)
TreeFam:
Gene Tree for ZNF19 (if available)

Paralogs for ZNF19 Gene

Paralogs for ZNF19 Gene

Selected SIMAP similar genes for ZNF19 Gene using alignment to 10 proteins:

Pseudogenes.org Pseudogenes for ZNF19 Gene

genes like me logo Genes that share paralogs with ZNF19: view

Variants for ZNF19 Gene

Sequence variations from dbSNP and Humsavar for ZNF19 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs2288486 -- 71,479,131(-) GTTCT(G/T)TCACA intron-variant
rs2288487 -- 71,475,685(+) AAGTA(A/G)GGGTG reference, synonymous-codon
rs2288488 -- 71,475,731(+) TCATA(C/G)GGTTT reference, synonymous-codon
rs2288489 -- 71,475,782(+) CTACT(C/G/T)GTGAA synonymous-codon, reference
rs3813743 -- 71,489,148(+) CCACA(A/G)TTGTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF19 Gene

Variant ID Type Subtype PubMed ID
nsv7285 OTHER Inversion 18451855

Relevant External Links for ZNF19 Gene

HapMap Linkage Disequilibrium report
ZNF19

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF19 Gene

Disorders for ZNF19 Gene

Relevant External Links for ZNF19

Genetic Association Database (GAD)
ZNF19
genes like me logo Genes that share disorders with ZNF19: view

No data available for UniProtKB/Swiss-Prot for ZNF19 Gene

Publications for ZNF19 Gene

  1. Characterization and mapping of human genes encoding zinc finger proteins. (PMID: 1946370) Bray P.L. … Dawid I.B. (Proc. Natl. Acad. Sci. U.S.A. 1991) 2 3 4
  2. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 2 3
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for ZNF19 Gene

Sources for ZNF19 Gene

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