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Aliases for ZNF19 Gene

Aliases for ZNF19 Gene

  • Zinc Finger Protein 19 2 3 5
  • Zinc Finger Protein 19 (KOX 12) 2 3
  • Zinc Finger Protein KOX12 3 4
  • KOX12 3 4

External Ids for ZNF19 Gene

Previous GeneCards Identifiers for ZNF19 Gene

  • GC16U990061
  • GC16M072231
  • GC16M071217
  • GC16M071284
  • GC16M070065
  • GC16M057276

Summaries for ZNF19 Gene

Entrez Gene Summary for ZNF19 Gene

  • The protein encoded by this gene contains a zinc finger, a nucleic acid-binding domain present in many transcription factors. This gene is located in a region next to ZNF23, a gene also encoding a zinc finger protein, on chromosome 16. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF19 Gene

ZNF19 (Zinc Finger Protein 19) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF454.

UniProtKB/Swiss-Prot for ZNF19 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF19 Gene

Additional gene information for ZNF19 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF19 Gene

Genomics for ZNF19 Gene

Regulatory Elements for ZNF19 Gene

Enhancers for ZNF19 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H071425 1.4 Ensembl ENCODE 49.9 +138.5 138477 1.7 PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 SLC30A9 DHX38 ZNF23 SF3B3 ZNF19 ENSG00000247324 ATXN1L PHLPP2 IST1 CMTR2 AP1G1
GH16H071707 1.3 FANTOM5 Ensembl ENCODE 48.1 -143.8 -143765 3.3 MAX RAD21 FOSL1 ZNF664 ZNF121 GATA3 ZNF316 SMC3 FOSL2 FOS ZNF19 PMFBP1 PHLPP2 MARVELD3 RNU6-208P HPR HYDIN ENSG00000261513 SNORA70D
GH16H071893 1.5 FANTOM5 ENCODE 20.1 -330.6 -330559 3.8 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC PPARGC1A ZFP41 PHLPP2 HYDIN IST1 ENSG00000247324 ZNF19 DHX38 ENSG00000261673 LOC105371335 TLE7 ENSG00000262120
GH16H070986 1.3 Ensembl ENCODE 22.2 +577.6 577628 1.1 PKNOX1 ZNF133 GLI4 ZNF2 FOS SP3 YY2 REST TSHZ1 ZNF518A SF3B3 PDPR PDXDC2P-NPIPB14P DDX19A LOC400541 EXOSC6 HYDIN DDX19B NPIPB14P PDXDC2P
GH16H070711 1.8 FANTOM5 Ensembl ENCODE dbSUPER 14.9 +850.6 850637 6 PKNOX1 FOXA2 MLX ARID4B DMAP1 YY1 SLC30A9 ZNF143 FOS MXD4 ZNF19 ZNF23 VAC14-AS1 FUK NPIPB14P EXOSC6 VAC14 PDXDC2P ENSG00000279412 PIR61375
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF19 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF19 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Locations for ZNF19 Gene

Genomic Locations for ZNF19 Gene
100,535 bases
Minus strand

Genomic View for ZNF19 Gene

Genes around ZNF19 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF19 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF19 Gene

Proteins for ZNF19 Gene

  • Protein details for ZNF19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 19
    Protein Accession:
    Secondary Accessions:
    • A8K895
    • Q86Y66
    • Q8NDE2
    • Q96M79
    • Q96NE5

    Protein attributes for ZNF19 Gene

    458 amino acids
    Molecular mass:
    52449 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAA36814.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF19 Gene


neXtProt entry for ZNF19 Gene

Post-translational modifications for ZNF19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF19 Gene

Domains & Families for ZNF19 Gene

Gene Families for ZNF19 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF19 Gene

Suggested Antigen Peptide Sequences for ZNF19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF19: view

Function for ZNF19 Gene

Molecular function for ZNF19 Gene

GENATLAS Biochemistry:
zinc finger protein 19 (KOX12) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding NAS 7557990
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF19: view
genes like me logo Genes that share phenotypes with ZNF19: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF19 Gene

Localization for ZNF19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF19 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF19 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus NAS 7557990
genes like me logo Genes that share ontologies with ZNF19: view

Pathways & Interactions for ZNF19 Gene

SuperPathways for ZNF19 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF19: view

Pathways by source for ZNF19 Gene

2 Reactome pathways for ZNF19 Gene

Gene Ontology (GO) - Biological Process for ZNF19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated NAS,IEA 7557990
genes like me logo Genes that share ontologies with ZNF19: view

No data available for SIGNOR curated interactions for ZNF19 Gene

Drugs & Compounds for ZNF19 Gene

No Compound Related Data Available

Transcripts for ZNF19 Gene

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF19 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c
SP1: - - -
SP2: - - - -
SP4: -
SP5: - -
SP6: -

Relevant External Links for ZNF19 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF19 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF19 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF19 Gene:


Evidence on tissue expression from TISSUES for ZNF19 Gene

  • Lung(4.1)
  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF19: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF19 Gene

Orthologs for ZNF19 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF19 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF19 33
  • 99.34 (n)
-- 34
  • 99 (a)
(Canis familiaris)
Mammalia ZNF19 33
  • 87.82 (n)
-- 34
  • 85 (a)
(Bos Taurus)
Mammalia ZNF19 33
  • 84.62 (n)
Species where no ortholog for ZNF19 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF19 Gene

Gene Tree for ZNF19 (if available)
Gene Tree for ZNF19 (if available)

Paralogs for ZNF19 Gene

Paralogs for ZNF19 Gene

(546) SIMAP similar genes for ZNF19 Gene using alignment to 10 proteins: Pseudogenes for ZNF19 Gene

genes like me logo Genes that share paralogs with ZNF19: view

Variants for ZNF19 Gene

Sequence variations from dbSNP and Humsavar for ZNF19 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000058973 -- 71,488,985(+) ATCAG(C/T)TGGAG intron-variant
rs1000300451 -- 71,488,579(+) GGATC(A/C/G)CCTGA intron-variant
rs1000317683 -- 71,488,343(+) TGACA(A/G)AACGA intron-variant
rs1000328498 -- 71,488,681(+) GTAAT(C/T)CCAGC intron-variant
rs1000532036 -- 71,477,145(+) TGTGG(G/T)TTACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF19 Gene

Variant ID Type Subtype PubMed ID
nsv7285 OTHER inversion 18451855

Variation tolerance for ZNF19 Gene

Residual Variation Intolerance Score: 34% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.24; 40.24% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF19 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF19 Gene

Disorders for ZNF19 Gene

Relevant External Links for ZNF19

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF19 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF19 Gene

Publications for ZNF19 Gene

  1. Characterization and mapping of human genes encoding zinc finger proteins. (PMID: 1946370) Bray P … Dawid IB (Proceedings of the National Academy of Sciences of the United States of America 1991) 2 3 4 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P … Ward DC (Genomics 1992) 2 3 60
  5. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen HJ (The New biologist 1990) 3 4 60

Products for ZNF19 Gene

Sources for ZNF19 Gene

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