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Aliases for ZNF184 Gene

Aliases for ZNF184 Gene

  • Zinc Finger Protein 184 2 3
  • Zinc Finger Protein 184 (Kruppel-Like) 2

External Ids for ZNF184 Gene

Previous GeneCards Identifiers for ZNF184 Gene

  • GC06M027476
  • GC06M027389
  • GC06M027435
  • GC06M027436
  • GC06M027526
  • GC06M027226

Summaries for ZNF184 Gene

GeneCards Summary for ZNF184 Gene

ZNF184 (Zinc Finger Protein 184) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF184 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF184 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF184 Gene

Genomics for ZNF184 Gene

Regulatory Elements for ZNF184 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF184 Gene

Start:
27,450,742 bp from pter
End:
27,473,118 bp from pter
Size:
22,377 bases
Orientation:
Minus strand

Genomic View for ZNF184 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF184 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF184 Gene

Proteins for ZNF184 Gene

  • Protein details for ZNF184 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q99676-ZN184_HUMAN
    Recommended name:
    Zinc finger protein 184
    Protein Accession:
    Q99676
    Secondary Accessions:
    • B2R715
    • O60792
    • Q8TBA9

    Protein attributes for ZNF184 Gene

    Size:
    751 amino acids
    Molecular mass:
    86174 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF184 Gene

Proteomics data for ZNF184 Gene at MOPED

Post-translational modifications for ZNF184 Gene

  • Ubiquitination at Lys416
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF184 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF184 Gene

Domains for ZNF184 Gene

Gene Families for ZNF184 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF184 Gene

Suggested Antigen Peptide Sequences for ZNF184 Gene

Graphical View of Domain Structure for InterPro Entry

Q99676

UniProtKB/Swiss-Prot:

ZN184_HUMAN :
  • Q99676
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF184: view

Function for ZNF184 Gene

Molecular function for ZNF184 Gene

GENATLAS Biochemistry: zinc finger 184,C2H2 type,Kruppel-like,Krab subfamily,predominantly but not exclusively expressed in testis
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF184 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0008270 zinc ion binding NAS 9073517
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with ZNF184: view

Phenotypes for ZNF184 Gene

GenomeRNAi human phenotypes for ZNF184:
genes like me logo Genes that share phenotypes with ZNF184: view

Animal Model Products

CRISPR Products

miRNA for ZNF184 Gene

miRTarBase miRNAs that target ZNF184

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF184 Gene

Localization for ZNF184 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF184 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF184 Gene COMPARTMENTS Subcellular localization image for ZNF184 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF184 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF184: view

Pathways for ZNF184 Gene

SuperPathways for ZNF184 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF184: view

Pathways by source for ZNF184 Gene

2 Reactome pathways for ZNF184 Gene

Gene Ontology (GO) - Biological Process for ZNF184 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF184: view

Transcripts for ZNF184 Gene

Unigene Clusters for ZNF184 Gene

Zinc finger protein 184:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF184

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF184 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - -
SP2: -
SP3:
SP4:

Relevant External Links for ZNF184 Gene

GeneLoc Exon Structure for
ZNF184
ECgene alternative splicing isoforms for
ZNF184

Expression for ZNF184 Gene

mRNA expression in normal human tissues for ZNF184 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF184 Gene

SOURCE GeneReport for Unigene cluster for ZNF184 Gene Hs.158174

mRNA Expression by UniProt/SwissProt for ZNF184 Gene

Q99676-ZN184_HUMAN
Tissue specificity: Predominant expression in testis
genes like me logo Genes that share expressions with ZNF184: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF184 Gene

Orthologs for ZNF184 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF184 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF184 35
  • 99.78 (n)
  • 99.87 (a)
ZNF184 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC515674 35
  • 91.43 (n)
  • 91.61 (a)
ZNF184 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF184 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp184 35
  • 84.94 (n)
  • 84.75 (a)
Zfp184 16
Zfp184 36
  • 84 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 38 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 35 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 55 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 41 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 48 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Zfp184 35
  • 85.19 (n)
  • 84.09 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11902 37
  • 26 (a)
CG8484 37
  • 27 (a)
CG9609 37
  • 31 (a)
CG4707 37
  • 31 (a)
Meics 37
  • 40 (a)
zf30C 37
  • 30 (a)
Kr 37
  • 44 (a)
CG6254 37
  • 36 (a)
Neu2 37
  • 34 (a)
CG7987 37
  • 33 (a)
CG18476 37
  • 26 (a)
CG4282 37
  • 29 (a)
CG6689 37
  • 34 (a)
wdn 37
  • 39 (a)
crol 37
  • 39 (a)
Species with no ortholog for ZNF184:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF184 Gene

ENSEMBL:
Gene Tree for ZNF184 (if available)
TreeFam:
Gene Tree for ZNF184 (if available)

Paralogs for ZNF184 Gene

Selected SIMAP similar genes for ZNF184 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF184 Gene

genes like me logo Genes that share paralogs with ZNF184: view

Variants for ZNF184 Gene

Sequence variations from dbSNP and Humsavar for ZNF184 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs7509 -- 27,451,068(-) GAAGG(A/C)TTTGG utr-variant-3-prime
rs726830 -- 27,455,411(+) TCAAT(A/G)TACAT intron-variant
rs726831 -- 27,455,469(+) TTTAA(C/T)TTGTA intron-variant
rs764460 -- 27,456,595(+) TCATA(A/G)AAAGG intron-variant
rs764461 -- 27,456,664(+) TGACA(A/T)AACAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF184 Gene

Variant ID Type Subtype PubMed ID
nsv830617 CNV Loss 17160897
nsv883508 CNV Loss 21882294

Relevant External Links for ZNF184 Gene

HapMap Linkage Disequilibrium report
ZNF184

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF184 Gene

Disorders for ZNF184 Gene

Relevant External Links for ZNF184

Genetic Association Database (GAD)
ZNF184
Human Genome Epidemiology (HuGE) Navigator
ZNF184
genes like me logo Genes that share disorders with ZNF184: view

No data available for UniProtKB/Swiss-Prot for ZNF184 Gene

Publications for ZNF184 Gene

  1. Common variants on chromosome 6p22.1 are associated with schizophrenia. (PMID: 19571809) Shi J. … Gejman P.V. (Nature 2009) 3 48
  2. Identification of a novel Krueppel-related zinc finger gene (ZNF184) mapping to 6p21.3. (PMID: 9073517) Goldwurm S. … Jazwinska E.C. (Genomics 1997) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF184 Gene

Sources for ZNF184 Gene

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