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Aliases for ZNF184 Gene

Aliases for ZNF184 Gene

  • Zinc Finger Protein 184 2 3 5
  • Zinc Finger Protein 184 (Kruppel-Like) 2 3
  • Kr-ZNF3 3

External Ids for ZNF184 Gene

Previous GeneCards Identifiers for ZNF184 Gene

  • GC06M027476
  • GC06M027389
  • GC06M027435
  • GC06M027436
  • GC06M027526
  • GC06M027226

Summaries for ZNF184 Gene

GeneCards Summary for ZNF184 Gene

ZNF184 (Zinc Finger Protein 184) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF607.

UniProtKB/Swiss-Prot for ZNF184 Gene

  • May be involved in transcriptional regulation.

Gene Wiki entry for ZNF184 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF184 Gene

Genomics for ZNF184 Gene

Regulatory Elements for ZNF184 Gene

Promoters for ZNF184 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF184 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF184 Gene

Chromosome:
6
Start:
27,450,742 bp from pter
End:
27,473,118 bp from pter
Size:
22,377 bases
Orientation:
Minus strand

Genomic View for ZNF184 Gene

Genes around ZNF184 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF184 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF184 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF184 Gene

Proteins for ZNF184 Gene

  • Protein details for ZNF184 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q99676-ZN184_HUMAN
    Recommended name:
    Zinc finger protein 184
    Protein Accession:
    Q99676
    Secondary Accessions:
    • B2R715
    • O60792
    • Q8TBA9

    Protein attributes for ZNF184 Gene

    Size:
    751 amino acids
    Molecular mass:
    86174 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF184 Gene

Proteomics data for ZNF184 Gene at MOPED

Post-translational modifications for ZNF184 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF184 Gene

No data available for DME Specific Peptides for ZNF184 Gene

Domains & Families for ZNF184 Gene

Gene Families for ZNF184 Gene

Protein Domains for ZNF184 Gene

Suggested Antigen Peptide Sequences for ZNF184 Gene

Graphical View of Domain Structure for InterPro Entry

Q99676

UniProtKB/Swiss-Prot:

ZN184_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 19 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF184: view

Function for ZNF184 Gene

Molecular function for ZNF184 Gene

GENATLAS Biochemistry:
zinc finger 184,C2H2 type,Kruppel-like,Krab subfamily,predominantly but not exclusively expressed in testis
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF184: view

Animal Model Products

CRISPR Products

miRNA for ZNF184 Gene

miRTarBase miRNAs that target ZNF184

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF184 Gene

Localization for ZNF184 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF184 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF184 Gene COMPARTMENTS Subcellular localization image for ZNF184 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF184 Gene

Pathways & Interactions for ZNF184 Gene

SuperPathways for ZNF184 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF184: view

Pathways by source for ZNF184 Gene

2 Reactome pathways for ZNF184 Gene

Gene Ontology (GO) - Biological Process for ZNF184 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF184: view

No data available for SIGNOR curated interactions for ZNF184 Gene

Drugs & Compounds for ZNF184 Gene

No Compound Related Data Available

Transcripts for ZNF184 Gene

Unigene Clusters for ZNF184 Gene

Zinc finger protein 184:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF184 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - -
SP2: -
SP3:
SP4:

Relevant External Links for ZNF184 Gene

GeneLoc Exon Structure for
ZNF184
ECgene alternative splicing isoforms for
ZNF184

Expression for ZNF184 Gene

mRNA expression in normal human tissues for ZNF184 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF184 Gene

This gene is overexpressed in Plasma (65.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF184 Gene



SOURCE GeneReport for Unigene cluster for ZNF184 Gene Hs.158174

mRNA Expression by UniProt/SwissProt for ZNF184 Gene

Q99676-ZN184_HUMAN
Tissue specificity: Predominant expression in testis.
genes like me logo Genes that share expression patterns with ZNF184: view

Protein tissue co-expression partners for ZNF184 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for ZNF184 Gene

Orthologs for ZNF184 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF184 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC515674 35
  • 91.43 (n)
  • 91.61 (a)
ZNF184 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp184 35
  • 84.94 (n)
  • 84.75 (a)
Zfp184 16
Zfp184 36
  • 84 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF184 35
  • 99.78 (n)
  • 99.87 (a)
ZNF184 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp184 35
  • 85.19 (n)
  • 84.09 (a)
dog
(Canis familiaris)
Mammalia ZNF184 36
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 38 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 35 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 55 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 56 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 49 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 45 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 48 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
-- 36
  • 51 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 41 (a)
OneToMany
-- 36
  • 43 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 48 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG11902 37
  • 26 (a)
CG18476 37
  • 26 (a)
CG4282 37
  • 29 (a)
CG4707 37
  • 31 (a)
CG6254 37
  • 36 (a)
CG6689 37
  • 34 (a)
CG7987 37
  • 33 (a)
CG8484 37
  • 27 (a)
CG9609 37
  • 31 (a)
Kr 37
  • 44 (a)
Meics 37
  • 40 (a)
Neu2 37
  • 34 (a)
wdn 37
  • 39 (a)
zf30C 37
  • 30 (a)
crol 37
  • 39 (a)
Species with no ortholog for ZNF184:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF184 Gene

ENSEMBL:
Gene Tree for ZNF184 (if available)
TreeFam:
Gene Tree for ZNF184 (if available)

Paralogs for ZNF184 Gene

(461) SIMAP similar genes for ZNF184 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF184 Gene

genes like me logo Genes that share paralogs with ZNF184: view

Variants for ZNF184 Gene

Sequence variations from dbSNP and Humsavar for ZNF184 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1883216 - 27,457,406(+) CACCG(A/C)TTCCT reference, missense, utr-variant-5-prime
rs7509 -- 27,451,068(-) GAAGG(A/C)TTTGG utr-variant-3-prime
rs764460 -- 27,456,595(+) TCATA(A/G)AAAGG intron-variant
rs764461 -- 27,456,664(+) TGACA(A/T)AACAA intron-variant
rs726830 -- 27,455,411(+) TCAAT(A/G)TACAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF184 Gene

Variant ID Type Subtype PubMed ID
nsv830617 CNV Loss 17160897
nsv883508 CNV Loss 21882294

Variation tolerance for ZNF184 Gene

Residual Variation Intolerance Score: 8.57% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.32; 26.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF184 Gene

HapMap Linkage Disequilibrium report
ZNF184

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF184 Gene

Disorders for ZNF184 Gene

Relevant External Links for ZNF184

Genetic Association Database (GAD)
ZNF184
Human Genome Epidemiology (HuGE) Navigator
ZNF184
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF184

No disorders were found for ZNF184 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF184 Gene

Publications for ZNF184 Gene

  1. Common variants on chromosome 6p22.1 are associated with schizophrenia. (PMID: 19571809) Shi J. … Gejman P.V. (Nature 2009) 3 48 67
  2. GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. (PMID: 24871463) Armstrong D.L. … Jacob C.O. (Genes Immun. 2014) 3
  3. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  4. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF184 Gene

Sources for ZNF184 Gene

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