Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF182 Gene

Aliases for ZNF182 Gene

  • Zinc Finger Protein 182 2 3
  • ZNF21 3 4 6
  • Zinc Finger Protein 21 (KOX 14) 2 3
  • Zinc Finger Protein KOX14 3 4
  • KOX14 3 4
  • Zinc Finger Protein 182 (HHZ150) 2
  • Zinc Finger Protein 21 4
  • HHZ150 3
  • Zfp182 3

External Ids for ZNF182 Gene

Previous HGNC Symbols for ZNF182 Gene

  • ZNF21

Previous GeneCards Identifiers for ZNF182 Gene

  • GC00U990427
  • GC0XM047719
  • GC0XM047834
  • GC0XM045547

Summaries for ZNF182 Gene

Entrez Gene Summary for ZNF182 Gene

  • Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a zinc finger protein, and belongs to the krueppel C2H2-type zinc-finger protein family. It may be involved in transcriptional regulation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2010]

GeneCards Summary for ZNF182 Gene

ZNF182 (Zinc Finger Protein 182) is a Protein Coding gene. An important paralog of this gene is ZNF248.

UniProtKB/Swiss-Prot for ZNF182 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF182 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF182 Gene

Genomics for ZNF182 Gene

Regulatory Elements for ZNF182 Gene

Genomic Location for ZNF182 Gene

47,974,851 bp from pter
48,003,995 bp from pter
29,145 bases
Minus strand

Genomic View for ZNF182 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF182 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF182 Gene

Proteins for ZNF182 Gene

  • Protein details for ZNF182 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 182
    Protein Accession:
    Secondary Accessions:
    • A2IDD7
    • Q3KP67
    • Q96QH7

    Protein attributes for ZNF182 Gene

    639 amino acids
    Molecular mass:
    73646 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF182 Gene


neXtProt entry for ZNF182 Gene

Proteomics data for ZNF182 Gene at MOPED

Post-translational modifications for ZNF182 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF182 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF182 Gene

Domains for ZNF182 Gene

Gene Families for ZNF182 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF182 Gene

Suggested Antigen Peptide Sequences for ZNF182 Gene

Graphical View of Domain Structure for InterPro Entry



  • P17025
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF182: view

Function for ZNF182 Gene

Molecular function for ZNF182 Gene

GENATLAS Biochemistry:
zinc finger 182,C2H2 type,Kruppel-like,Krab subfamily,involved in differentiation and development of heart
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF182 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF182: view

Phenotypes for ZNF182 Gene

GenomeRNAi human phenotypes for ZNF182:
genes like me logo Genes that share phenotypes with ZNF182: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF182 Gene

Localization for ZNF182 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF182 Gene

Subcellular locations from

Jensen Localization Image for ZNF182 Gene COMPARTMENTS Subcellular localization image for ZNF182 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF182 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF182: view

Pathways for ZNF182 Gene

SuperPathways for ZNF182 Gene

No Data Available

Interacting Proteins for ZNF182 Gene

Gene Ontology (GO) - Biological Process for ZNF182 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF182: view

No data available for Pathways by source for ZNF182 Gene

Transcripts for ZNF182 Gene

Unigene Clusters for ZNF182 Gene

Zinc finger protein 182:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF182

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF182 Gene

ExUns: 1 ^ 2a · 2b ^ 3
SP1: -
SP2: -

Relevant External Links for ZNF182 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF182 Gene

mRNA expression in normal human tissues for ZNF182 Gene

Protein differential expression in normal tissues for ZNF182 Gene

This gene is overexpressed in Uterus (68.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF182 Gene

SOURCE GeneReport for Unigene cluster for ZNF182 Gene Hs.189690

genes like me logo Genes that share expressions with ZNF182: view

Expression partners for ZNF182 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF182 Gene

Orthologs for ZNF182 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF182 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF182 35
  • 91.87 (n)
  • 93.21 (a)
ZNF182 36
  • 88 (a)
(Canis familiaris)
Mammalia ZNF182 35
  • 90.36 (n)
  • 91.11 (a)
ZNF182 36
  • 90 (a)
(Mus musculus)
Mammalia Zfp182 35
  • 85.7 (n)
  • 87.79 (a)
Zfp182 16
Zfp182 36
  • 84 (a)
(Pan troglodytes)
Mammalia ZNF182 35
  • 98.32 (n)
  • 97.56 (a)
ZNF182 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Zfp182 35
  • 85.8 (n)
  • 89.43 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 53 (a)
-- 36
  • 47 (a)
-- 36
  • 43 (a)
-- 36
  • 42 (a)
-- 36
  • 45 (a)
-- 36
  • 46 (a)
-- 36
  • 44 (a)
-- 36
  • 42 (a)
-- 36
  • 43 (a)
-- 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 41 (a)
Species with no ortholog for ZNF182:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF182 Gene

Gene Tree for ZNF182 (if available)
Gene Tree for ZNF182 (if available)

Paralogs for ZNF182 Gene

Selected SIMAP similar genes for ZNF182 Gene using alignment to 1 proteins: Pseudogenes for ZNF182 Gene

genes like me logo Genes that share paralogs with ZNF182: view

Variants for ZNF182 Gene

Sequence variations from dbSNP and Humsavar for ZNF182 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs492359 -- 47,994,483(-) TTTCC(G/T)ctctg intron-variant
rs500561 -- 47,981,251(-) ttcct(G/T)cctct intron-variant
rs519609 -- 47,974,902(+) GTACA(C/T)AGTAC utr-variant-3-prime
rs534472 -- 47,999,566(-) acccc(C/G)caacc intron-variant
rs558127 -- 47,979,555(-) CATCC(A/G)TTTGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF182 Gene

Variant ID Type Subtype PubMed ID
dgv2442e1 CNV Complex 17122850
esv8782 OTHER Inversion 19470904
dgv2443e1 CNV Complex 17122850
nsv6890 CNV Loss 18451855
dgv14n29 CNV Complex 16826518
nsv471601 CNV Gain 15918152
nsv522886 CNV Gain 19592680
dgv2444e1 CNV Complex 17122850
esv2752324 CNV Gain 17911159
esv25781 CNV Gain 19812545
esv32909 CNV Gain+Loss 17666407

Relevant External Links for ZNF182 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF182 Gene

Disorders for ZNF182 Gene

Relevant External Links for ZNF182

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for ZNF182 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZNF182 Gene

Publications for ZNF182 Gene

  1. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. (PMID: 2014798) Huebner K. … Thiesen H.J. (Am. J. Hum. Genet. 1991) 2 3
  2. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  3. Clustered organization of KrA1ppel zinc-finger genes at Xp11.23, flanking a translocation breakpoint at OATL1: a physical map with locus assignments for ZNF21, ZNF41, ZNF81, and ELK1. (PMID: 8088786) Knight J.C. … Coleman M.P. (Genomics 1994) 2 3
  4. Localization of a novel zinc finger gene to the human chromosome 7p11.2-p12 by fluorescence in situ hybridization. (PMID: 8914609) Wang R. … Liew C.C. (Somat. Cell Mol. Genet. 1996) 2 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for ZNF182 Gene

Sources for ZNF182 Gene

Back to Top