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Aliases for ZNF177 Gene

Aliases for ZNF177 Gene

  • Zinc Finger Protein 177 2 3
  • PIGX 3

External Ids for ZNF177 Gene

Previous GeneCards Identifiers for ZNF177 Gene

  • GC19P009595
  • GC19P009696
  • GC19P009097
  • GC19P009114
  • GC19P009334
  • GC19P009475
  • GC19P009437

Summaries for ZNF177 Gene

GeneCards Summary for ZNF177 Gene

ZNF177 (Zinc Finger Protein 177) is a Protein Coding gene. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. An important paralog of this gene is ZNF558.

UniProtKB/Swiss-Prot for ZNF177 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF177 Gene

Genomics for ZNF177 Gene

Regulatory Elements for ZNF177 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF177 Gene

Start:
9,363,020 bp from pter
End:
9,382,617 bp from pter
Size:
19,598 bases
Orientation:
Plus strand

Genomic View for ZNF177 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF177 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF177 Gene

Proteins for ZNF177 Gene

  • Protein details for ZNF177 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q13360-ZN177_HUMAN
    Recommended name:
    Zinc finger protein 177
    Protein Accession:
    Q13360
    Secondary Accessions:
    • B4DY57
    • E9PDG0
    • I3L0I4
    • Q96ER2

    Protein attributes for ZNF177 Gene

    Size:
    481 amino acids
    Molecular mass:
    54782 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF177 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF177 Gene

Proteomics data for ZNF177 Gene at MOPED

Post-translational modifications for ZNF177 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF177 Gene

No data available for DME Specific Peptides for ZNF177 Gene

Domains for ZNF177 Gene

Gene Families for ZNF177 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF177 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q13360

UniProtKB/Swiss-Prot:

ZN177_HUMAN :
  • Q13360
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 10 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF177: view

Function for ZNF177 Gene

Molecular function for ZNF177 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF177 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF177: view

Phenotypes for ZNF177 Gene

GenomeRNAi human phenotypes for ZNF177:
genes like me logo Genes that share phenotypes with ZNF177: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF177

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF177 Gene

Localization for ZNF177 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF177 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF177 Gene COMPARTMENTS Subcellular localization image for ZNF177 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF177 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with ZNF177: view

Pathways for ZNF177 Gene

genes like me logo Genes that share pathways with ZNF177: view

Interacting Proteins for ZNF177 Gene

Selected Interacting proteins: Q13360-ZN177_HUMAN for ZNF177 Gene via UniProtKB

Symbol External ID(s) Details
ARHGAP21

Gene Ontology (GO) - Biological Process for ZNF177 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter TAS 8661005
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated --
genes like me logo Genes that share ontologies with ZNF177: view

Transcripts for ZNF177 Gene

mRNA/cDNA for ZNF177 Gene

Unigene Clusters for ZNF177 Gene

Zinc finger protein 177:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF177

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF177 Gene

No ASD Table

Relevant External Links for ZNF177 Gene

GeneLoc Exon Structure for
ZNF177
ECgene alternative splicing isoforms for
ZNF177

Expression for ZNF177 Gene

mRNA expression in normal human tissues for ZNF177 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ZNF177 Gene

SOURCE GeneReport for Unigene cluster for ZNF177 Gene Hs.728944

genes like me logo Genes that share expressions with ZNF177: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF177 Gene

Orthologs for ZNF177 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF177 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
OneToMany
ZNF177 35
  • 99.51 (n)
  • 98.75 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 64 (a)
OneToMany
ZNF177 35
  • 83.02 (n)
  • 76.94 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 48 (a)
OneToMany
ZNF177 35
  • 83.86 (n)
  • 78.5 (a)
mouse
(Mus musculus)
Mammalia 5730507C01Rik 36
  • 36 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 33 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
-- 36
  • 29 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ZNF557 36
  • 26 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG3407 37
  • 40 (a)
BG:DS02740.8 37
  • 37 (a)
Species with no ortholog for ZNF177:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF177 Gene

ENSEMBL:
Gene Tree for ZNF177 (if available)
TreeFam:
Gene Tree for ZNF177 (if available)

Paralogs for ZNF177 Gene

Paralogs for ZNF177 Gene

genes like me logo Genes that share paralogs with ZNF177: view

Variants for ZNF177 Gene

Sequence variations from dbSNP and Humsavar for ZNF177 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
VAR_031692 -
VAR_031693 -
VAR_057401 -

Structural Variations from Database of Genomic Variants (DGV) for ZNF177 Gene

Variant ID Type Subtype PubMed ID
nsv911020 CNV Gain 21882294

Relevant External Links for ZNF177 Gene

HapMap Linkage Disequilibrium report
ZNF177

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF177 Gene

Disorders for ZNF177 Gene

No disorders were found for ZNF177 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF177 Gene

Publications for ZNF177 Gene

  1. Transcripts from a novel human KRAB zinc finger gene contain spliced Alu and endogenous retroviral segments. (PMID: 8661005) Baban S. … Mager D.L. (Genomics 1996) 3 4
  2. Repetitive elements in the 5' untranslated region of a human zinc- finger gene modulate transcription and translation efficiency. (PMID: 11549323) Landry J.R. … Mager D.L. (Genomics 2001) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3

Products for ZNF177 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF177
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF177
    • Block miRNA regulation of ZNF177 using miScript Target Protectors

    Sources for ZNF177 Gene

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