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Aliases for ZNF17 Gene

Aliases for ZNF17 Gene

  • Zinc Finger Protein 17 2 3 5
  • Zinc Finger Protein 17 (HPF3, KOX 10) 2 3
  • Zinc Finger Protein KOX10 3 4
  • Zinc Finger Protein HPF3 3 4
  • KOX10 3 4
  • KIAA1947 4
  • HPF3 3

External Ids for ZNF17 Gene

Previous GeneCards Identifiers for ZNF17 Gene

  • GC19P058829
  • GC19P058376
  • GC19P062539
  • GC19P062615
  • GC19P062616
  • GC19P062617
  • GC19P057922
  • GC19P054235

Summaries for ZNF17 Gene

GeneCards Summary for ZNF17 Gene

ZNF17 (Zinc Finger Protein 17) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF417.

UniProtKB/Swiss-Prot for ZNF17 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF17 Gene

Genomics for ZNF17 Gene

Regulatory Elements for ZNF17 Gene

Enhancers for ZNF17 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF17 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF17 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF17 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF17 gene promoter:

Genomic Location for ZNF17 Gene

57,411,161 bp from pter
57,421,953 bp from pter
10,793 bases
Plus strand

Genomic View for ZNF17 Gene

Genes around ZNF17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF17 Gene

Proteins for ZNF17 Gene

  • Protein details for ZNF17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 17
    Protein Accession:
    Secondary Accessions:
    • B3KXU2
    • B3KY20
    • Q8N7M1
    • Q8N893
    • Q8TF54

    Protein attributes for ZNF17 Gene

    662 amino acids
    Molecular mass:
    77204 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC04956.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC05252.1; Type=Erroneous termination; Positions=461; Note=Translated as Gln.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF17 Gene


neXtProt entry for ZNF17 Gene

Proteomics data for ZNF17 Gene at MOPED

Post-translational modifications for ZNF17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF17 Gene

No data available for DME Specific Peptides for ZNF17 Gene

Domains & Families for ZNF17 Gene

Gene Families for ZNF17 Gene

Protein Domains for ZNF17 Gene

Suggested Antigen Peptide Sequences for ZNF17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF17: view

Function for ZNF17 Gene

Molecular function for ZNF17 Gene

GENATLAS Biochemistry:
zinc finger protein 17 (KOX10) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF17: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF17 Gene

Localization for ZNF17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF17 Gene

Subcellular locations from

Jensen Localization Image for ZNF17 Gene COMPARTMENTS Subcellular localization image for ZNF17 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF17 Gene

Pathways & Interactions for ZNF17 Gene

SuperPathways for ZNF17 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF17: view

Pathways by source for ZNF17 Gene

2 Reactome pathways for ZNF17 Gene

Gene Ontology (GO) - Biological Process for ZNF17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF17: view

No data available for SIGNOR curated interactions for ZNF17 Gene

Drugs & Compounds for ZNF17 Gene

(1) Drugs for ZNF17 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(1) Additional Compounds for ZNF17 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with ZNF17: view

Transcripts for ZNF17 Gene

Unigene Clusters for ZNF17 Gene

Zinc finger protein 17:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF17 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d
SP2: -
SP3: -
SP4: - -

Relevant External Links for ZNF17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF17 Gene

mRNA expression in normal human tissues for ZNF17 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF17 Gene

SOURCE GeneReport for Unigene cluster for ZNF17 Gene Hs.729403

genes like me logo Genes that share expression patterns with ZNF17: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF17 Gene

Orthologs for ZNF17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF17 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF17 35
  • 71.81 (n)
  • 61.57 (a)
-- 36
  • 49 (a)
(Pan troglodytes)
Mammalia ZNF17 35
  • 99.3 (n)
  • 98.64 (a)
Species with no ortholog for ZNF17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF17 Gene

Gene Tree for ZNF17 (if available)
Gene Tree for ZNF17 (if available)

Paralogs for ZNF17 Gene

(494) SIMAP similar genes for ZNF17 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF17: view

Variants for ZNF17 Gene

Sequence variations from dbSNP and Humsavar for ZNF17 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs2014827 - 57,419,935(+) CCTCA(A/C)ATGCA reference, missense
rs12980700 -- 57,418,915(+) TTGAG(A/G)TGGAG intron-variant
rs8101982 -- 57,414,615(+) caggt(A/G)tgagc intron-variant
rs12982691 -- 57,418,888(+) GTTTT(G/T)TTTTT intron-variant
rs886208 -- 57,418,423(+) CACTG(C/G)TTGTG intron-variant

Variation tolerance for ZNF17 Gene

Residual Variation Intolerance Score: 22.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.42; 42.70% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZNF17 Gene

Disorders for ZNF17 Gene

Relevant External Links for ZNF17

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF17 Gene

Publications for ZNF17 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. (PMID: 2014798) Huebner K. … Thiesen H.J. (Am. J. Hum. Genet. 1991) 2 3
  3. Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Kruppel. (PMID: 2115127) Kato N. … Cohen M. (Mol. Cell. Biol. 1990) 2 3
  4. A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities. (PMID: 24104479) Vizeacoumar F.J. … Moffat J. (Mol. Syst. Biol. 2013) 3
  5. Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PMID: 17043677) Camargo L.M. … Brandon N.J. (Mol. Psychiatry 2007) 3

Products for ZNF17 Gene

Sources for ZNF17 Gene