ZNF17 Gene
protein-coding GIFtS: 52
GCID: GC19P057922
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zinc finger protein 17(Previous names: zinc finger protein 17 (HPF3, KOX 10) )
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Aliases
for ZNF17 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 171 2 | | Zinc Finger Protein HPF32 3 | | KOX101 2 3 | | Zinc Finger Protein KOX102 3 | | HPF31 2 | | FLJ408641 | | Zinc Finger Protein 17 (HPF3, KOX 10)1 2 | | FLJ460581 | | KIAA19471 3 | | FLJ466151 |
Export aliases for ZNF17 gene to outside databasesPrevious GC identifers: GC19P058829 GC19P058376 GC19P062539 GC19P062615 GC19P062616 GC19P062617 GC19P054235 |
Summaries
for ZNF17 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZNF17_HUMAN, P17021Function: May be involved in transcriptional regulation
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Genomic Views
for ZNF17 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF17 gene promoter:
HTF XBP-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF17
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF17 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.4 Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19q13.43ZNF17 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P057922: view genomic region
(about GC identifiers)
Start:
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57,922,529 bp from pter |
End:
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57,933,307 bp from pter |
Size:
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10,779 bases |
Orientation:
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plus strand |
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Proteins
for ZNF17 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZNF17_HUMAN, P17021 (See
protein sequence)Recommended Name: Zinc finger protein 17 Size: 662 amino acids; 77204 Da
Subcellular location: Nucleus (Potential)
Sequence caution: Sequence=BAC04956.1; Type=Erroneous initiation; Sequence=BAC05252.1; Type=Erroneous termination;Positions=461; Note=Translated as Gln;
Secondary accessions: B3KXU2 B3KY20 Q8N7M1 Q8N893 Q8TF54Alternative splicing: 3 isoforms: P17021-1 P17021-2 P17021-3 Explore the universe of human proteins at neXtProt for ZNF17: NX_P17021
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P17021
ZNF17 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_008890.2
ENSEMBL proteins: ENSP00000302455 Reactome Protein details: P17021
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF17 for ontologies About GeneDecksing
ZNF17 Antibody Products:
Assay Products for ZNF17: |
Protein
Domains /
Families
for ZNF17 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF17 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P17021ProtoNet protein and cluster: P17021 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZNF17_HUMAN, P17021Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 17 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF17 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZNF17_HUMAN, P17021Function: May be involved in transcriptional regulation Genatlas biochemistry entry for ZNF17:zinc finger protein 17 (KOX10) (C2H2 type,Kruppel-like)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF17
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF17
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF17 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF17 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF17:
|
Pathways & Interactions
for ZNF17 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF17
ZNF17 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF17
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZNF17 (P170213 ENSP000003024554) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF17 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF17 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ZNF17 for compounds About GeneDecksing
 Browse Tocris compounds for ZNF17
2 Novoseek chemical compound relationships for ZNF17 gene About this table
Search CenterWatch for drugs/clinical trials and news about ZNF17
|
Transcripts
for ZNF17 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF17 gene: NM_006959.2 Unigene Cluster for ZNF17: Zinc finger protein 17 Hs.729403 [show with all ESTs]Unigene Representative Sequence: AK1284711 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000307658(uc021vck.1 uc002qoo.1 uc002qop.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF17
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF17
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF17 (NM_006959) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF17 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF17 |
Additional cDNA sequence: AK097123.1 AK098183.1 AK127948.1 AK128471.1 X52341.1 6 DOTS entries: DT.101973760 DT.40264556 DT.100020506 DT.100020504 DT.121454074 DT.121454139 24/25 AceView cDNA sequences (see all 25): X52341 AA454141 AK098183 BU569994 AA604653 AK128471 BX487316 AA418246 AK097123 AK127948 AB075827 BQ575507 BP871984 BU681756 BG943376 BQ937753 BF064020 NM_006959 BG116989 BM127451 BU664322 D81878 AA418360 CK906093
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF17 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d |
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| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF17
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Expression
for ZNF17 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF17 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTTGCTTAA
About this image
See ZNF17 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF17
SOURCE GeneReport for Unigene cluster: Hs.729403
SABiosciences Custom PCR Arrays for ZNF17
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF17
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF17 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF17 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF17 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF17 |
Orthologs
for ZNF17 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF17 (if available)
TreeFam Gene Tree for ZNF17 (if available) |
Paralogs
for ZNF17 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF17 gene
- ZNF5492 ZNF2112 ZNF4172 ZNF7922 ZNF7492 ZNF5512 ZNF7762 ZNF5472
- ZNF4162 ZNF5482 ZNF3042 ZNF587B2 ZNF7732 ZNF1322 ZIK12 ZNF6712
- ZNF1342 ZNF4182 ZNF2562 ZNF1542 ZNF5522 ZNF7722 ZNF5302 ZNF4192
18/485 SIMAP similar genes for ZNF17 using alignment to 3 protein entries: ZNF17_HUMAN (see all proteins)
(see all similar genes):FLJ00301 ZNF78L1 ZSCAN16 DKFZp686N14223 HZF36 kr-znf3
ZNF81 ZNF345 ZNF502 ZNF ZNF669 DKFZp313M0722
DKFZp666C237 ZNF146 ZNF157 ZNF323 ZNF391 ZNF818P
ZNF17 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF17 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF17 (57922529 - 57933307 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF17: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF17 |
|
Disorders
/ Diseases
for ZNF17 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF17 for disorders About GeneDecksing
5  diseases for ZNF17: About MalaCardsparainfluenza virus type 3 croup influenza choriocarcinoma
schizophrenia
1 disease from the University of Copenhagen DISEASES database for ZNF17:Croup 3 Novoseek disease relationships for ZNF17 gene About this table
Export disorders for ZNF17 gene to outside databases
|
Publications
for ZNF17 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF17 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with ZNF17) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PubMed id 11853319)1, 2 Nagase T.... Ohara O. (2001)
- Twenty-seven nonoverlapping zinc finger cDNAs from hu man T cells map to nine different chromosomes with apparent clustering. (PubMed id 2014798)1, 3 Huebner K....Thiesen H.J. (1991)
- Multiple genes encoding zinc finger domains are expressed in human T cells. (PubMed id 2288909)1, 2 Thiesen H.-J. (1990)
- Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Kruppel. (PubMed id 2115127)1, 3 Kato N.... Cohen M. (1990)
- Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia. (PubMed id 17043677)1 Camargo L.M....Brandon N.J. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Fusion properties of cells infected with human parainfluenza virus type 3: receptor requirements for viral spread and virus-mediated membrane fusion. (PubMed id 1328668)9 Moscona A. and Peluso R.W. (1992)
- The use of a quantitative fusion assay to evaluate HN-receptor interaction for human parainfluenza virus type 3. (PubMed id 10603317)9 Levin Perlman S....Moscona A. (1999)
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External Searches for ZNF17 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF17 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF17 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF17 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF17 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF17 gene:
Search GeneIP for patents involving ZNF17
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF17 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF17 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF17 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF17 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF17 | | OriGene 3'-UTR Clone for ZNF17 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF17 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF17 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF17 | | OriGene Custom Protein Services for ZNF17 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF17 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF17 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF17 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF17 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF17 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF17 |
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 | | | ZNF17 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF17 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF17 |
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