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Aliases for ZNF17 Gene

Aliases for ZNF17 Gene

  • Zinc Finger Protein 17 2 3
  • Zinc Finger Protein 17 (HPF3, KOX 10) 2 3
  • Zinc Finger Protein KOX10 3 4
  • Zinc Finger Protein HPF3 3 4
  • KOX10 3 4
  • KIAA1947 4
  • ZNF175 6
  • OTK18 6
  • HPF3 3

External Ids for ZNF17 Gene

Summaries for ZNF17 Gene

GeneCards Summary for ZNF17 Gene

ZNF17 (Zinc Finger Protein 17) is a Protein Coding gene. Diseases associated with ZNF17 include croup and parainfluenza virus type 3. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF417.

UniProtKB/Swiss-Prot for ZNF17 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF17 Gene

Genomics for ZNF17 Gene

Genomic Location for ZNF17 Gene

Start:
57,411,161 bp from pter
End:
57,421,939 bp from pter
Size:
10,779 bases
Orientation:
Plus strand

Genomic View for ZNF17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF17 Gene

Regulatory Elements for ZNF17 Gene

Transcription factor binding sites by QIAGEN in the ZNF17 gene promoter:

Proteins for ZNF17 Gene

  • Protein details for ZNF17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17021-ZNF17_HUMAN
    Recommended name:
    Zinc finger protein 17
    Protein Accession:
    P17021
    Secondary Accessions:
    • B3KXU2
    • B3KY20
    • Q8N7M1
    • Q8N893
    • Q8TF54

    Protein attributes for ZNF17 Gene

    Size:
    662 amino acids
    Molecular mass:
    77204 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04956.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAC05252.1; Type=Erroneous termination; Positions=461; Note=Translated as Gln.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF17 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF17 Gene

Proteomics data for ZNF17 Gene at MOPED

Post-translational modifications for ZNF17 Gene

No Post-translational modifications

Other Protein References for ZNF17 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF17 Gene

Domains for ZNF17 Gene

Gene Families for ZNF17 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZNF17_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • P17021
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • P17021
Similarity:
  • Contains 17 C2H2-type zinc fingers.:
    • P17021
genes like me logo Genes that share domains with ZNF17: view

Function for ZNF17 Gene

Molecular function for ZNF17 Gene

GENATLAS Biochemistry: zinc finger protein 17 (KOX10) (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF17: view

Phenotypes for ZNF17 Gene

GenomeRNAi human phenotypes for ZNF17:
genes like me logo Genes that share phenotypes with ZNF17: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF17 Gene

Localization for ZNF17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF17 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF17 Gene COMPARTMENTS Subcellular localization image for ZNF17 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF17: view

Pathways for ZNF17 Gene

SuperPathways for ZNF17 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF17: view

Pathways by source for ZNF17 Gene

2 Reactome pathways for ZNF17 Gene

Gene Ontology (GO) - Biological Process for ZNF17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF17: view

Compounds for ZNF17 Gene

(2) Novoseek inferred chemical compound relationships for ZNF17 Gene

Compound -log(P) Hits PubMed IDs
zanamivir 82.7 1
sialic acid 75.8 8
genes like me logo Genes that share compounds with ZNF17: view

Transcripts for ZNF17 Gene

Unigene Clusters for ZNF17 Gene

Zinc finger protein 17:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF17 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d
SP1:
SP2: -
SP3: -
SP4: - -

Relevant External Links for ZNF17 Gene

GeneLoc Exon Structure for
ZNF17
ECgene alternative splicing isoforms for
ZNF17

Expression for ZNF17 Gene

mRNA expression in normal human tissues for ZNF17 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF17 Gene

SOURCE GeneReport for Unigene cluster for ZNF17 Gene Hs.729403

genes like me logo Genes that share expressions with ZNF17: view

Orthologs for ZNF17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF17 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF17 36
  • 99.3 (n)
  • 98.64 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 49 (a)
ManyToMany
ZNF17 36
  • 71.81 (n)
  • 61.57 (a)
Species with no ortholog for ZNF17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF17 Gene

ENSEMBL:
Gene Tree for ZNF17 (if available)
TreeFam:
Gene Tree for ZNF17 (if available)

Paralogs for ZNF17 Gene

Selected SIMAP similar genes for ZNF17 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF17: view

Variants for ZNF17 Gene

Sequence variations from dbSNP and Humsavar for ZNF17 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs886208 -- 57,418,423(+) CACTG(C/G)TTGTG intron-variant
rs2014827 - 57,419,935(+) CCTCA(A/C)ATGCA missense, reference, utr-variant-5-prime
rs2023761 -- 57,421,635(+) agtac(C/T)gttaa utr-variant-3-prime
rs2158009 -- 57,420,659(+) TGCAA(C/T)GAATG reference, synonymous-codon
rs3053672 -- 57,418,928(-) CATTG(-/CAA)CAAGA intron-variant

Relevant External Links for ZNF17 Gene

HapMap Linkage Disequilibrium report
ZNF17

No data available for Structural Variations from Database of Genomic Variants (DGV) for ZNF17 Gene

Disorders for ZNF17 Gene

(1) University of Copenhagen DISEASES for ZNF17 Gene

(3) Novoseek inferred disease relationships for ZNF17 Gene

Disease -log(P) Hits PubMed IDs
parainfluenza 91.2 13
influenza 39.4 2
virus infection 9.51 2
genes like me logo Genes that share disorders with ZNF17: view

No data available for UniProtKB/Swiss-Prot for ZNF17 Gene

Publications for ZNF17 Gene

  1. Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering. (PMID: 2014798) Huebner K. … Thiesen H.J. (Am. J. Hum. Genet. 1991) 2 3
  2. Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Kruppel. (PMID: 2115127) Kato N. … Cohen M. (Mol. Cell. Biol. 1990) 2 3
  3. Multiple genes encoding zinc finger domains are expressed in human T cells. (PMID: 2288909) Thiesen H.-J. (New Biol. 1990) 3 4
  4. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 3 4
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4

Products for ZNF17 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF17
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF17
    • Block miRNA regulation of ZNF17 using miScript Target Protectors

    Sources for ZNF17 Gene

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