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Aliases for ZNF169 Gene

Aliases for ZNF169 Gene

  • Zinc Finger Protein 169 2 3
  • EC 63

External Ids for ZNF169 Gene

Previous GeneCards Identifiers for ZNF169 Gene

  • GC09U990077
  • GC09M088768
  • GC09P090320
  • GC09P092363
  • GC09P092382
  • GC09P094101
  • GC09P096061
  • GC09P097021
  • GC09P066701

Summaries for ZNF169 Gene

GeneCards Summary for ZNF169 Gene

ZNF169 (Zinc Finger Protein 169) is a Protein Coding gene. Diseases associated with ZNF169 include hereditary sensory neuropathy. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HKR1.

UniProtKB/Swiss-Prot for ZNF169 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF169 Gene

Genomics for ZNF169 Gene

Regulatory Elements for ZNF169 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF169 Gene

94,259,296 bp from pter
94,303,009 bp from pter
43,714 bases
Plus strand

Genomic View for ZNF169 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF169 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF169 Gene

Proteins for ZNF169 Gene

  • Protein details for ZNF169 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 169
    Protein Accession:
    Secondary Accessions:
    • A2AGP5
    • A8K127
    • Q6PI28

    Protein attributes for ZNF169 Gene

    603 amino acids
    Molecular mass:
    68488 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH47702.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAF82431.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF169 Gene

Proteomics data for ZNF169 Gene at MOPED

Selected DME Specific Peptides for ZNF169 Gene

Post-translational modifications for ZNF169 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF169 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Domains for ZNF169 Gene

Gene Families for ZNF169 Gene

  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry



  • Q14929
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF169: view

Function for ZNF169 Gene

Molecular function for ZNF169 Gene

GENATLAS Biochemistry: zinc finger protein 169 (C2H2,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Enzyme Numbers (IUBMB) for ZNF169 Gene

Gene Ontology (GO) - Molecular Function for ZNF169 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF169: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF169

In Situ Assay Products

Flow Cytometry Products

No data available for Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF169 Gene

Localization for ZNF169 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF169 Gene

Subcellular locations from

Jensen Localization Image for ZNF169 Gene COMPARTMENTS Subcellular localization image for ZNF169 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF169 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF169: view

Pathways for ZNF169 Gene

SuperPathways for ZNF169 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF169: view

Pathways by source for ZNF169 Gene

2 Reactome pathways for ZNF169 Gene

Gene Ontology (GO) - Biological Process for ZNF169 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF169: view

Transcripts for ZNF169 Gene

Unigene Clusters for ZNF169 Gene

Zinc finger protein 169:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF169

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF169 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b
SP1: - - -
SP2: -
SP3: - -
SP4: -

Relevant External Links for ZNF169 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF169 Gene

mRNA expression in normal human tissues for ZNF169 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF169 Gene

SOURCE GeneReport for Unigene cluster for ZNF169 Gene Hs.387623

mRNA Expression by UniProt/SwissProt for ZNF169 Gene

Tissue specificity: Highly expressed in kidney, weakly expressed in heart, liver, spleen, and small intestine. Not expressed in adult brain or spinal cord
genes like me logo Genes that share expressions with ZNF169: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF169 Gene

Orthologs for ZNF169 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZNF169 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF169 35
  • 99.23 (n)
  • 98.34 (a)
ZNF169 36
  • 98 (a)
(Bos Taurus)
Mammalia ZNF169 35
  • 81.38 (n)
  • 78.76 (a)
ZNF169 36
  • 78 (a)
(Canis familiaris)
Mammalia ZNF169 35
  • 81.1 (n)
  • 80.11 (a)
(Mus musculus)
Mammalia Zfp169 35
  • 72.26 (n)
  • 63.56 (a)
Zfp169 16
Zfp169 36
  • 43 (a)
(Rattus norvegicus)
Mammalia Zfp169 35
  • 72.28 (n)
  • 63.95 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes RSF2 38
Species with no ortholog for ZNF169:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF169 Gene

Gene Tree for ZNF169 (if available)
Gene Tree for ZNF169 (if available)

Paralogs for ZNF169 Gene

Paralogs for ZNF169 Gene

Selected SIMAP similar genes for ZNF169 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF169: view

Variants for ZNF169 Gene

Sequence variations from dbSNP and Humsavar for ZNF169 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs592574 -- 94,265,558(+) ctggg(G/T)gacag intron-variant
rs615313 -- 94,265,566(-) gtctc(A/G)ctctg intron-variant
rs615338 -- 94,265,551(-) ccagg(A/C)tggag intron-variant
rs722353 -- 94,299,703(+) TGCCC(C/T)TGTGG utr-variant-5-prime, intron-variant
rs1064560 -- 94,295,532(+) CTTTC(A/G)CCTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF169 Gene

Variant ID Type Subtype PubMed ID
nsv831655 CNV Gain 17160897
nsv893592 CNV Gain 21882294
esv1152524 CNV Insertion 17803354

Relevant External Links for ZNF169 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF169 Gene

Disorders for ZNF169 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for ZNF169 Gene including...

Search for ZNF169 Gene in MalaCards »

Relevant External Links for ZNF169

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with ZNF169: view

No data available for UniProtKB/Swiss-Prot for ZNF169 Gene

Publications for ZNF169 Gene

  1. Characterization of a YAC contig containing the NBCCS locus and a novel Kruppel-type zinc finger sequence on chromosome segment 9q22.3. (PMID: 9071574) Chidambaram A. … Dean M. (Genes Chromosomes Cancer 1997) 2 3 4
  2. Pulsed-field gel electrophoresis and FISH mapping of chromosome 9q22: placement of a novel zinc finger gene within the NBCCS and ESS1 region. (PMID: 9186526) Levanat S. … Bale A.E. (Cytogenet. Cell Genet. 1997) 2 3
  3. Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. (PMID: 22344221) Okada Y. … Tanaka T. (Nat. Genet. 2012) 3 48
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF169 Gene

Sources for ZNF169 Gene

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