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Aliases for ZNF165 Gene

Aliases for ZNF165 Gene

  • Zinc Finger Protein 165 2 3
  • Cancer/Testis Antigen 53 2 3 4
  • LD65 3 4 6
  • Zinc Finger And SCAN Domain-Containing Protein 7 3 4
  • ZSCAN7 3 4
  • CT53 3 4
  • ZPF165 4

External Ids for ZNF165 Gene

Previous GeneCards Identifiers for ZNF165 Gene

  • GC06P028106
  • GC06P028155
  • GC06P028159
  • GC06P028164
  • GC06P028165
  • GC06P028046
  • GC06P027856

Summaries for ZNF165 Gene

Entrez Gene Summary for ZNF165 Gene

  • This gene encodes a member of the Kruppel family of zinc finger proteins. Members of this DNA-binding protein family act as transcriptional regulators. This gene is located within a cluster of zinc finger family members. The encoded protein may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF165 Gene

ZNF165 (Zinc Finger Protein 165) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZNF396.

UniProtKB/Swiss-Prot for ZNF165 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF165 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF165 Gene

Genomics for ZNF165 Gene

Regulatory Elements for ZNF165 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF165 Gene

28,080,704 bp from pter
28,089,563 bp from pter
8,860 bases
Plus strand

Genomic View for ZNF165 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF165 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF165 Gene

Proteins for ZNF165 Gene

  • Protein details for ZNF165 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 165
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ZNF165 Gene

    485 amino acids
    Molecular mass:
    55771 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF165 Gene

Proteomics data for ZNF165 Gene at MOPED

Post-translational modifications for ZNF165 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF165 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF165 Gene

Domains for ZNF165 Gene

Gene Families for ZNF165 Gene

  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF165 Gene

Graphical View of Domain Structure for InterPro Entry



  • P49910
  • Contains 1 SCAN box domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF165: view

Function for ZNF165 Gene

Molecular function for ZNF165 Gene

GENATLAS Biochemistry: zinc finger protein 165,C2H2 type,Kruppel-like,specifically expressed in testis
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF165 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF165: view

Animal Model Products

CRISPR Products

miRNA for ZNF165 Gene

miRTarBase miRNAs that target ZNF165

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF165 Gene

Localization for ZNF165 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF165 Gene

Subcellular locations from

Jensen Localization Image for ZNF165 Gene COMPARTMENTS Subcellular localization image for ZNF165 gene
Compartment Confidence
nucleus 5
cytoskeleton 1
lysosome 1

Gene Ontology (GO) - Cellular Components for ZNF165 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF165: view

Pathways for ZNF165 Gene

SuperPathways for ZNF165 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF165 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF165: view

No data available for Pathways by source for ZNF165 Gene

Transcripts for ZNF165 Gene

mRNA/cDNA for ZNF165 Gene

(7) Additional mRNA sequences :
(26) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF165 Gene

Zinc finger protein 165:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF165

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF165 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5
SP2: - -
SP3: -
SP4: - - - -

Relevant External Links for ZNF165 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF165 Gene

mRNA expression in normal human tissues for ZNF165 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ZNF165 Gene

This gene is overexpressed in Testis (11.7).

SOURCE GeneReport for Unigene cluster for ZNF165 Gene Hs.55481

mRNA Expression by UniProt/SwissProt for ZNF165 Gene

Tissue specificity: Expressed specifically in testis
genes like me logo Genes that share expressions with ZNF165: view

In Situ Assay Products

No data available for Protein expression for ZNF165 Gene

Orthologs for ZNF165 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF165 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF165 35
  • 99.59 (n)
  • 99.38 (a)
ZNF165 36
  • 99 (a)
(Bos Taurus)
Mammalia ZNF165 35
  • 86.19 (n)
  • 80.41 (a)
ZNF165 36
  • 80 (a)
(Canis familiaris)
Mammalia ZNF165 35
  • 84.24 (n)
  • 75.79 (a)
Species with no ortholog for ZNF165:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF165 Gene

Gene Tree for ZNF165 (if available)
Gene Tree for ZNF165 (if available)

Paralogs for ZNF165 Gene

Selected SIMAP similar genes for ZNF165 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF165: view

Variants for ZNF165 Gene

Sequence variations from dbSNP and Humsavar for ZNF165 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs203866 -- 28,083,572(-) CTGCA(C/T)AGTCT intron-variant
rs203867 -- 28,083,040(-) ATGAA(C/T)ATATA intron-variant
rs1321504 -- 28,084,991(+) ATTTC(C/G)TATTT intron-variant, upstream-variant-2KB
rs1321505 -- 28,085,045(+) ATTTC(A/C)TGTTT intron-variant, upstream-variant-2KB
rs2295594 -- 28,085,319(+) ATATA(A/G)TAAAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF165 Gene

Variant ID Type Subtype PubMed ID
nsv830619 CNV Loss 17160897
esv33436 CNV Gain 17666407
dgv1005n67 CNV Gain 20364138

Relevant External Links for ZNF165 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF165 Gene

Disorders for ZNF165 Gene

No disorders were found for ZNF165 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF165 Gene

Publications for ZNF165 Gene

  1. Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis. (PMID: 7490084) Tirosvoutis K.N. … Affara N.A. (Genomics 1995) 2 3 4
  2. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain. (PMID: 9244436) Lee P.L. … Beutler E. (Genomics 1997) 3 4
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for ZNF165 Gene

Sources for ZNF165 Gene

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