ZNF160 Gene

Aliases
for ZNF160 gene

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Previous GC identifers: GC19U990141 GC19M058102 GC19M058260 GC19M049897

Summaries
for ZNF160 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Genomic Views
for ZNF160 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000019.9  NT_011109.17  NC_018930.2  

SwitchGear Promoter luciferase reporter plasmid: ZNF160 promoter sequence

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF160

ZNF160 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M053569:  view genomic region     (about GC identifiers)

Proteins
for ZNF160 gene

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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Explore the universe of human proteins at neXtProt for ZNF160: NX_Q9HCG1

Explore proteomics data for ZNF160 at MOPED

Post-translational modifications: 

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Domains /
Families
for ZNF160 gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
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ProtoNet protein and cluster: Q9HCG1

Find genes that share domains with ZNF160           About GenesLikeMe

Function
for ZNF160 gene

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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     Gene Ontology (GO): 3 molecular function terms:    About this table

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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF160

Localization
for ZNF160 gene

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Subcellular locations from COMPARTMENTS: 

Compartment	Confidence
nucleus	5
cytosol	2

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Gene Ontology (GO): 2 cellular component terms:    About this table

Pathways & Interactions
for ZNF160 gene

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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SuperPaths for ZNF160 About     See pathways by source

Powered by

	SuperPath	Contained pathways About
1	Gene Expression	Generic Transcription Pathway 0.40 Gene Expression 0.40

3 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for ZNF160

	MSP-RON Signaling
	Blood Coagulation Cascade
	Intrinsic Prothrombin Activation Pathway

1 Reactome Pathway for ZNF160

Generic Transcription Pathway

Gene Ontology (GO): 3 biological process terms:    About this table

Drugs & Compounds
for ZNF160 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
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Transcripts
for ZNF160 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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Expression
for ZNF160 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ZNF160 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CCTGTAAATC

About this image

Thymus (Hematopoietic System)
Double Positive Thymocytes Thymus
Blood (Cardiovascular System)
Double Positive Thymocytes Thymus

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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF160

Orthologs
for ZNF160 gene

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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Paralogs
for ZNF160 gene

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
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Paralogs for ZNF160 gene

ZNF616²  ZNF473²  ZNF493²  ZNF546²  ZNF99²  ZNF836²  ZNF721²  ZNF594²  

ZFP62²  ZNF841²  ZNF43²  ZNF780B²  ZNF197²  ZNF107²  ZNF585A²  ZNF808²  

ZNF347²  ZNF845²  ZNF585B²  ZNF658²  ZNF629²  ZNF624²  ZNF268²  ZNF814²  

Selected SIMAP similar genes for ZNF160 using alignment to 6 protein entries:     ZN160_HUMAN (see all proteins) (see all similar genes):

DKFZp686B16128    ZNF78L1    kr-znf3    ZNF616    HZF30    ZFS-1

ZNF702P    ZNF665    DKFZp686M04222    HZF36    ZFS-4    ZNF213

ZNF826P    ZNF146    ZNF818P    ZNF420    HZF16    ZNF232

Find genes that share paralogs with ZNF160           About GenesLikeMe


2 Pseudogenes.org Pseudogenes for ZNF160
PGOHUM00000262842 PGOHUM00000248805

Genomic Variants
for ZNF160 gene

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for ZNF160 (see all 961)    About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1430200861,2	C	--	53569428(+)	CCTCCC/TAAAGT	3	--	ds5001		0	--	--	--	--
rs1482047451,2		--	53569458(+)	GCCACC/TGTGCC	3	--	ds5001		0	--	--	--	--
rs1427510421,2		--	53569484(+)	TTCTCA/GCATTC	3	--	ds5001		0	--	--	--	--
rs795831831,2	C,F	--	53569523(+)	CAAGAT/GGCAAA	3	--	ds5001		3		CSA WA NA	240
rs3297371,2	C,H	--	53569527(-)	ATGCTA/TTGCAT	3	--	ds5001		20		MN NS EA NA WA CSA	877
rs1124651021,2	C,F	--	53569712(+)	AAATGC/TGGTTA	3	--	ds5001		2		CSA WA	120
rs1929645211,2		--	53569787(+)	CCTAGC/TGGTGT	3	--	ds5001		0	--	--	--	--
rs1473794751,2		--	53569806(+)	TGTGTC/TATGGA	3	--	ds5001		0	--	--	--	--
rs1384450441,2	C	--	53569922(+)	ATTCTA/GAATAA	3	--	ut31		0	--	--	--	--
rs779383941,2	C	--	53569968(+)	AGTTCT/CACTAA	3	--	ut31		2		CSA WA	120

HapMap Linkage Disequilibrium report for ZNF160 (53569859 - 53606689 bp)

Structural Variations
     Database of Genomic Variants (DGV) Selected variations for ZNF160 (see all 17):    About this table    

Variant ID	Type	Subtype	PubMed ID
esv2718787	CNV	Deletion	23290073
esv2488809	CNV	Deletion	19546169
nsv435700	CNV	Deletion	17901297
esv2718810	CNV	Deletion	23290073
esv8151	CNV	Loss	19470904
nsv428370	CNV	Loss	18775914
nsv912345	CNV	Loss	21882294
nsv470153	CNV	Loss	18288195
nsv912343	CNV	Loss	21882294
dgv429n27	CNV	Gain	19166990

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing ZNF160

DNA2.0 Custom Variant and Variant Library Synthesis for ZNF160

Disorders / Diseases
for ZNF160 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
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Publications
for ZNF160 gene

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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1. Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PubMed id 7865130)^{1, 2, 3} Abrink M.... Hellman L. (DNA Cell Biol. 1995)
2. Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19. (PubMed id 11410164)^{1, 2} Mark C.... Hellman L. (DNA Cell Biol. 2001)
3. Characterization of long cDNA clones from human adult spleen. (PubMed id 11214971)^{1, 2} Hattori A.... Ohara O. (DNA Res. 2000)
4. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)^{1, 2} Nagase T.... Ohara O. (DNA Res. 2000)
5. A novel C2H2 zinc-finger protein gene (ZNF160) maps to human chromosome 19q13.3-q13.4. (PubMed id 7774943)^{1, 3} Halford S....Scambler P.J. (Genomics 1995)
6. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (amp 2012)
7. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)¹ Wang J....Yang X. (Mol. Syst. Biol. 2011)
8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (amp 2011)
9. Epigenetic regulation of TLR4 gene expression in intestinal epithelial cells for the maintenance of intestinal homeostasis. (PubMed id 19846881)¹ Takahashi K....Kaminogawa S. (J. Immunol. 2009)
10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (Genome Res. 2006)

External Searches for ZNF160 gene

Genome Databases showing ZNF160 gene

Other Databases showing ZNF160 gene

Specialized Databases showing ZNF160 gene

Products
for ZNF160 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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