Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF160 Gene

Aliases for ZNF160 Gene

  • Zinc Finger Protein 160 2 3
  • Zinc Finger Protein HZF5 3 4
  • Zinc Finger Protein Kr18 3 4
  • HKr18 3 4
  • KRAB Zinc Finger Protein KR18 3
  • Zinc Finger Protein 5 3
  • KIAA1611 4
  • HZF5 3
  • KR18 3
  • F11 3

External Ids for ZNF160 Gene

Summaries for ZNF160 Gene

Entrez Gene Summary for ZNF160 Gene

  • The protein encoded by this gene is a Kruppel-related zinc finger protein which is characterized by the presence of an N-terminal repressor domain, the Kruppel-associated box (KRAB). The KRAB domain is a potent repressor of transcription; thus this protein may function in transcription regulation. Three alternative transcripts encoding the same protein have been described. [provided by RefSeq, Jul 2008]

GeneCards Summary for ZNF160 Gene

ZNF160 (Zinc Finger Protein 160) is a Protein Coding gene. Among its related pathways are Hemostasis and Formation of Fibrin Clot (Clotting Cascade). An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF160 Gene

  • May be involved in transcriptional regulation

Gene Wiki entry for ZNF160 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF160 Gene

Genomics for ZNF160 Gene

Genomic Location for ZNF160 Gene

Start:
53,065,928 bp from pter
End:
53,103,436 bp from pter
Size:
37,509 bases
Orientation:
Minus strand

Genomic View for ZNF160 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF160 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF160 Gene

Regulatory Elements for ZNF160 Gene

Transcription factor binding sites by QIAGEN in the ZNF160 gene promoter:

Proteins for ZNF160 Gene

  • Protein details for ZNF160 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HCG1-ZN160_HUMAN
    Recommended name:
    Zinc finger protein 160
    Protein Accession:
    Q9HCG1
    Secondary Accessions:
    • Q14589
    • Q504Q8
    • Q96JC5
    • Q9BVY9
    • Q9H7N6

    Protein attributes for ZNF160 Gene

    Size:
    818 amino acids
    Molecular mass:
    94112 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA55528.1; Type=Miscellaneous discrepancy; Note=Dubious alternative splicing.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF160 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF160 Gene

Proteomics data for ZNF160 Gene at MOPED

Post-translational modifications for ZNF160 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF160 Gene

No data available for DME Specific Peptides for ZNF160 Gene

Domains for ZNF160 Gene

Gene Families for ZNF160 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN160_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q9HCG1
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9HCG1
Similarity:
  • Contains 20 C2H2-type zinc fingers.:
    • Q9HCG1
genes like me logo Genes that share domains with ZNF160: view

Function for ZNF160 Gene

Molecular function for ZNF160 Gene

GENATLAS Biochemistry: zinc finger protein 160 (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF160: view
genes like me logo Genes that share phenotypes with ZNF160: view

miRNA for ZNF160 Gene

miRTarBase miRNAs that target ZNF160

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF160 Gene

Localization for ZNF160 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF160 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF160 Gene COMPARTMENTS Subcellular localization image for ZNF160 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF160: view

Pathways for ZNF160 Gene

genes like me logo Genes that share pathways with ZNF160: view

Pathways by source for ZNF160 Gene

Interacting Proteins for ZNF160 Gene

Gene Ontology (GO) - Biological Process for ZNF160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0030097 hemopoiesis NAS 11410164
genes like me logo Genes that share ontologies with ZNF160: view

Transcripts for ZNF160 Gene

Unigene Clusters for ZNF160 Gene

Zinc finger protein 160:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF160 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11
SP1: - - - - - - - - - - - -
SP2: - - - - - - - - - - -
SP3: - -
SP4: - - - -
SP5: - - - - - -
SP6: - - -
SP7: - - - - -
SP8:
SP9:
SP10: - -

Relevant External Links for ZNF160 Gene

GeneLoc Exon Structure for
ZNF160
ECgene alternative splicing isoforms for
ZNF160

Expression for ZNF160 Gene

mRNA expression in normal human tissues for ZNF160 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF160 Gene

SOURCE GeneReport for Unigene cluster for ZNF160 Gene Hs.655967

mRNA Expression by UniProt/SwissProt for ZNF160 Gene

Q9HCG1-ZN160_HUMAN
Tissue specificity: Ubiquitous.
genes like me logo Genes that share expressions with ZNF160: view

Orthologs for ZNF160 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF160 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 51 (a)
ManyToMany
ZNF160 36
  • 99.43 (n)
  • 99.27 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 49 (a)
ManyToMany
-- 37
  • 44 (a)
ManyToMany
-- 37
  • 48 (a)
ManyToMany
-- 37
  • 49 (a)
ManyToMany
-- 37
  • 49 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp160 16
Zfp52 37
  • 40 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 37 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 42 (a)
ManyToMany
-- 37
  • 37 (a)
ManyToMany
-- 37
  • 38 (a)
ManyToMany
CSA.1668 37
  • 32 (a)
ManyToMany
Species with no ortholog for ZNF160:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF160 Gene

ENSEMBL:
Gene Tree for ZNF160 (if available)
TreeFam:
Gene Tree for ZNF160 (if available)

Paralogs for ZNF160 Gene

Selected SIMAP similar genes for ZNF160 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for ZNF160 Gene

genes like me logo Genes that share paralogs with ZNF160: view

Variants for ZNF160 Gene

Sequence variations from dbSNP and Humsavar for ZNF160 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs167917 -- 53,082,022(-) ttgtt(C/T)ttcta intron-variant
rs167918 -- 53,074,415(-) GCTGG(C/G)ATTAC intron-variant
rs179312 -- 53,071,855(-) ATAAT(A/G)AATAT intron-variant
rs184516 -- 53,083,878(-) tgagc(A/G)tactt intron-variant
rs184517 -- 53,081,369(-) ttatt(C/T)gtcag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF160 Gene

Variant ID Type Subtype PubMed ID
esv2718787 CNV Deletion 23290073
dgv1116e1 CNV Complex 17122850
nsv428370 CNV Loss 18775914
nsv912342 CNV Gain 21882294
nsv912343 CNV Loss 21882294
nsv9748 CNV Gain 18304495
dgv3991n71 CNV Gain+Loss 21882294
nsv435700 CNV Deletion 17901297
esv2488809 CNV Deletion 19546169
nsv527053 CNV Gain 19592680
nsv912345 CNV Loss 21882294
nsv470153 CNV Loss 18288195
dgv429n27 CNV Gain 19166990
esv2718810 CNV Deletion 23290073
esv8151 CNV Loss 19470904
nsv515862 CNV Gain+Loss 19592680
dgv3992n71 CNV Gain 21882294

Relevant External Links for ZNF160 Gene

HapMap Linkage Disequilibrium report
ZNF160

Disorders for ZNF160 Gene

No disorders were found for ZNF160 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF160 Gene

Publications for ZNF160 Gene

  1. Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937. (PMID: 7865130) Abrink M. … Hellman L. (DNA Cell Biol. 1995) 2 3 4
  2. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 3 4
  3. Characterization of long cDNA clones from human adult spleen. (PMID: 11214971) Hattori A. … Ohara O. (DNA Res. 2000) 3 4
  4. Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19. (PMID: 11410164) Mark C. … Hellman L. (DNA Cell Biol. 2001) 3 4
  5. A novel C2H2 zinc-finger protein gene (ZNF160) maps to human chromosome 19q13.3-q13.4. (PMID: 7774943) Halford S. … Scambler P.J. (Genomics 1995) 2 3

Products for ZNF160 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF160
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF160
    • Block miRNA regulation of ZNF160 using miScript Target Protectors

    Sources for ZNF160 Gene

    Back to Top

    Content