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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF137P Gene

pseudogene   GIFtS: 34
GCID: GC19P053099

Zinc Finger Protein 137, Pseudogene

(Previous names: zinc finger protein 137 (clone pHZ-30), zinc finger protein...)
(Previous symbol: ZNF137)
  Search for ZNF137P
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 137, Pseudogene1 2     Zinc Finger Protein 137 (Pseudogene)1
ZNF1371 2 3 5     pHZ-302
Zinc Finger Protein 1371     Zinc Finger Protein 137 Pseudogene3
Zinc Finger Protein 137 (Clone PHZ-30)1     

External Ids:    HGNC: 129211   Entrez Gene: 76962   Ensembl: ENSG000001238707   OMIM: 6040795   UniProtKB: P527433   

Export aliases for ZNF137P gene to outside databases

Previous GC identifer: GC19P049428


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZNF137P Gene: 
ZNF137P (zinc finger protein 137, pseudogene) is a pseudogene.

UniProtKB/Swiss-Prot: ZN137_HUMAN, P52743
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011109.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for ZNF137P
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for ZNF137P

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF137P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.41   HGNC cytogenetic band: 19q13.4

ZNF137P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF137P gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P053099:  view genomic region     (about GC identifiers)

Start:
53,091,758 bp from pter      End:
53,103,405 bp from pter
Size:
11,648 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZN137_HUMAN, P52743 (See protein sequence)
Recommended Name: Putative zinc finger protein 137  
Size: 207 amino acids; 24115 Da
Subcellular location: Nucleus (Potential)
Caution: Product of a dubious CDS prediction. May be produced at very low levels due to a premature stop codon in
the mRNA, leading to nonsense-mediated mRNA decay
Secondary accessions: Q2TBC7

Explore the universe of human proteins at neXtProt for ZNF137P: NX_P52743

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P52743

  • ZNF137P Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry P52743

    ProtoNet protein and cluster: P52743

    1 Blocks protein domain: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: ZN137_HUMAN, P52743
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 5 C2H2-type zinc fingers


    ZNF137P for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN137_HUMAN, P52743
    Function: May be involved in transcriptional regulation

    Phenotypes:
         1 GenomeRNAi human phenotype for ZNF137P:

     Decreased POU5F1-GFP protein e 

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF137P

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF137P (ZN137)

    Search CenterWatch for drugs/clinical trials and news about ZNF137P

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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    About This Section

    REFSEQ mRNAs for ZNF137P gene: 
    NM_003438.2  

    Unigene Cluster for ZNF137P:

    Zinc finger protein 137, pseudogene
    Hs.373648  [show with all ESTs]
    Unigene Representative Sequence: NR_023311
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000597158 ENST00000456718 ENST00000333303 ENST00000406609 ENST00000446680

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    Additional mRNA sequence: NR_023311.1 

    3 DOTS entries:

    DT.40293189  DT.92415807  DT.100008251 

    24/70 AceView cDNA sequences (see all 70):

    CD244192 BQ690668 BC067346 BQ008299 AI953831 BQ958705 AI003260 BP871716 
    AK095562 BQ685199 CO249446 AK001753 AI244141 CO249357 BX955279 BC080612 
    BG324525 BQ060959 CO250069 AL833487 BQ016962 CO249449 CF595699 NM_018260 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF137P expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZNF137P Expression
    About this image


    Genevestigator expression for ZNF137P

    SOURCE GeneReport for Unigene cluster: Hs.373648
        SABiosciences Custom PCR Arrays for ZNF137P
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for ZNF137P (if available)
    TreeFam Gene Tree for ZNF137P (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF137P gene
    18/546 SIMAP similar genes for ZNF137P using alignment to 1 protein entry:     ZN137_HUMAN(see all similar genes):
    ZNF845    ZNF860    ZNF808    ZNF397    ZNF675    ZNF135
    ZNF813    ZNF420    HZF30    ZNF132    ZNF429    ZNF492
    ZNF519    ZNF56    ZNF708    ZNF724P    ZNF78L1    ZNF93

    ZNF137P for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/147 SNPs in ZNF137P are shown (see all 147)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1860267741,2
    --53097941(+) CTGTAA/TTTTTA 1 -- us2k10--------
    rs1915235291,2
    --53098065(+) CTGGCC/TCGTTC 1 -- us2k10--------
    rs116729991,2
    C,F,A,H--53098101(+) CATCTT/CTCACT 1 -- us2k18Minor allele frequency- C:0.40NA WA CSA EA 252
    rs129795461,2
    C,F,A--53098186(+) TCCTAC/GGGAGG 1 -- us2k111Minor allele frequency- G:0.43NA WA CSA EA 374
    rs81106861,2
    C,F,A,H--53098296(+) atggcG/Atgatc 1 -- us2k14Minor allele frequency- A:0.38NA CSA 8
    rs81107941,2
    C,F,A,H--53098306(+) ctccaG/Ctcact 1 -- us2k16Minor allele frequency- C:0.33NA CSA 12
    rs1506096451,2
    C--53098514(+) AACTA-/TTAT  
            
    TTACC
    1 -- us2k10--------
    rs65096531,2
    C,F,A,H--53098551(+) GGATTC/ATTGCT 1 -- us2k17Minor allele frequency- A:0.36NA WA CSA 14
    rs1480680361,2
    --53098568(+) CCCAGA/GCTGGA 1 -- us2k10--------
    rs113267551,2
    C,F--53098690(+) GCTAAT/-TTTTT 1 -- us2k13Minor allele frequency- -:0.50NA CSA 6

    HapMap Linkage Disequilibrium report for ZNF137P (53091758 - 53103405 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for ZNF137P:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2718787CNV Deletion23290073
    esv2718786CNV Deletion23290073
    nsv833874CNV Loss17160897
    nsv912304CNV Loss21882294
    nsv458743CNV Loss19166990
    nsv510772CNV Loss20534489
    dgv3981n71CNV Gain21882294
    dgv3980n71CNV Gain21882294
    nsv828616CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ZNF137P for disorders           About MalaCards
    OMIM gene information: 604079    OMIM disorders: --


    ZNF137P for disorders           About GeneDecksing


    Export disorders for ZNF137P gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF137P gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ZNF137P)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders. (PubMed id 7557990)1, 2, 3 Tommerup N. and Vissing H. (1995)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    4. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7696 HGNC: 12921 AceView: FLJ10891andZNF578andLOC388558 Ensembl:ENSG00000123870 euGenes: HUgn7696
    ECgene: ZNF137P H-InvDB: ZNF137P

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF137P Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF137P gene:
    Search GeneIP for patents involving ZNF137P

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
    transforming growth factor, beta 1
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